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Magnetic Resonance of Myelin, Myelination and Myelin Disorders

Magnetic Resonance of Myelin, Myelination and Myelin Disorders
Author: Marjo S. van der Knaap
Publisher: Springer Science & Business Media
Total Pages: 1255
Release: 2013-06-29
Genre: Medical
ISBN: 3662030780

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Clearly structured, each chapter describes: * clinical features and laboratory investigations * pathology * pathogenetic considerations * therapy * case presentation * MRI and spectroscopy of a specific myelin disorder Completely updated and expanded by 20 chapters to include the latest information on: - inborn errors of metabolism and neurodegenerative disorders - the role of subcellular structures - enzyme biochemistry - the pathophysiological mechanisms of posthypoxic-ischemic cerebral damage - inflammatory and infectious disorders Plus: Greater coverage of the genetic and pathophysiological mechanisms underlying white matter disorders. Finally: 250 high-quality illustrations depict rare disorders which previously were only described.


Magnetic Resonance of Myelination and Myelin Disorders

Magnetic Resonance of Myelination and Myelin Disorders
Author: Marjo S. van der Knaap
Publisher: Springer Science & Business Media
Total Pages: 1097
Release: 2005-08-15
Genre: Medical
ISBN: 3540276602

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Our thanks go to our colleagues at the VU Univer- Preface to the Third Edition sity Medical Center and to those in other hospitals Reading through the prefaces of the two previous edi- who referred their patients to us. We are indebted to tions,we can say that much of what was said there still all colleagues who allowed us to use their MR images, holds. At the same time,however,much has changed. published or unpublished,making it possible for us to There has been immense progress in the technical present illustrations of nearly all known white matter possibilities of magnetic resonance and in the know- disorders. Two colleagues were particularly helpful ledge of genetic defects, biochemical abnormalities, and provided us with essential and unpublished f- and cellular processes underlying myelin disorders. ures: our friends Susan Blaser,from the Hospital for This immense progress has prompted us to embark Sick Children in Toronto,and Zoltán Patay,from the upon the enormous task of rewriting the previous King Faisal Hospital in Riyadh. edition and adding 40 chapters. In doing so we have Many people at the VU University Medical Center tried to cover most white matter disorders,hereditary have been of great technical help to us in producing and acquired,and to present a collection of images to high quality images and in providing secretarial illustrate the field to the fullest possible extent. This assistance. The contributions of these people are edition will therefore be more complete than the pre- mentioned separately in the acknowledgements.


Magnetic Resonance of Myelin, Myelination, and Myelin Disorders

Magnetic Resonance of Myelin, Myelination, and Myelin Disorders
Author: Marjo S. van der Knaap
Publisher:
Total Pages: 558
Release: 1995
Genre: Demyelination
ISBN: 9783662030806

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This is the second, completely rewritten edition of the widely acclaimed book on MR of myelin, myelination and myelin disorders (1989). In the last five years many new data became available with regard to genetics, molecular biology, the role of cellular substructures on one side and on the other side regarding the growing experience with MR patterns of less common myelin disorders. Not only, therefore, the text has been updated, but many new chapters have been added on disorders of which previously the white matter involvement was less clear. The acquired myelin disorders were reorganized and their backgrounds were more extensively elucidated, to place the MR examinations in the clinical context where they belong.


Myelination and Demyelination

Myelination and Demyelination
Author: Seung U. Kim
Publisher: Springer Science & Business Media
Total Pages: 276
Release: 2012-12-06
Genre: Science
ISBN: 1461307775

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In June 1987, neurobiologists, immunologists, molecular biologists, virologists and neurologists from several countries met in Vancouver to discuss recent advances of relevance to multiple sclerosis. The symposium was a part of the 22nd Canadian Congress of Neurological Sciences meeting and was sponsored by funds from the Multiple Sclerosis Society of Canada and the Medical Research Council of Canada. The presentations covered five major topics: basic neurobiology, molecular biology, the role of viruses in demyelination, immune function and dysfunction in multiple sclerosis, and clinical magnetic resonance imaging studies. It was heartening to note that scientists from several different disciplines were working towards a common end-point: the understanding and treatment of multiple sclerosis. In this book, speakers at the symposium have each presented a chapter of their findings and discussions. In addition, some non-participants at the symposium have been invited to submit chapters in order to give this volume a more complete scope. It is hoped that the reader will find this book a useful reference for several subjects of interest to multiple sclerosis. In closing, I would like to thank the following for their help and support: the Multiple Sclerosis Society of Canada and the Medical Research Council of Canada for their financial support; the contributors of this book for their manuscripts; Dr. A. Eisen, Mrs. K. Eisen, Mrs. P. Bodnarchuk and Mrs. M. Kim for their efforts in planning and organizing the symposium; and Ms. Catherine Schikowski for her secretarial assistance. Seung U. Kim, M.D. Ph.D.


MR Imaging in White Matter Diseases of the Brain and Spinal Cord

MR Imaging in White Matter Diseases of the Brain and Spinal Cord
Author: Massimo Filippi
Publisher: Springer Science & Business Media
Total Pages: 508
Release: 2005-05-09
Genre: Medical
ISBN: 9783540402305

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In recent decades, the use of neuroimaging techniques has resulted in outstanding progress in the diagnosis and management of neurological diseases, and this is particularly true of those diseases that affect the white matter of the brain and spinal cord. This book, written by internationally acclaimed experts, comprises a series of comprehensive and up-to-date reviews on the use of MR imaging in these major neurological conditions. The diverse available MR techniques, such as magnetization transfer MRI, diffusion-weighted MRI, MR spectroscopy, functional MRI, cell-specific MRI, perfusion MRI, and microscopic imaging with ultra-high field MRI, offer an extraordinarily powerful means of gaining fundamental in vivo insights into disease processes. The strengths and weaknesses of all these techniques in the study of multiple sclerosis and other relevant diseases are extensively considered. After an introductory section on neuroimaging technology, subsequent sections address disorders of myelination, demyelinating diseases, immune-mediated disorders, and white matter disorders related to aging and other conditions. This book provides a valuable summary of the state of the art in the field, and defines important areas for future research.


Myelin Biology and Disorders

Myelin Biology and Disorders
Author: Robert A. Lazzarini
Publisher:
Total Pages:
Release: 2004
Genre:
ISBN: 0124395104

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Quantitative Magnetic Resonance Imaging

Quantitative Magnetic Resonance Imaging
Author: Nicole Seiberlich
Publisher: Academic Press
Total Pages: 1094
Release: 2020-11-18
Genre: Computers
ISBN: 0128170581

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Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches