Lymphatic Metastasis And Sentinel Lymphonodectomy PDF Download
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| Author | : P.M. Schlag |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 520 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 3642571514 |
Download Lymphatic Metastasis and Sentinel Lymphonodectomy Book in PDF, ePub and Kindle
Metastases determine malignancy. The main attention so far has been focused upon organ metastases. The molecular mechanisms thereof, while far from being totally elucidated, are increasingly well understood. Modern diagnostic tools now enable detection and precise localization of small lesions. In contrast, our knowl edge and diagnostic capabilities regarding metastatic spread to the'lymphatic system are rather limited. However, there have re cently been a number of interesting advances. It is the aim of this volume to submit these developments to detailed analysis. The therapeutic relevance of enhanced sensitivity in detection of lymph node metastases has to be considered in the light of in creased morbidity versus eventual prognostic improvements by modification of therapy. An interesting concept which might im prove diagnostic accuracy while reducing operative morbidity is the "sentinel node" technique. Surgical standards are lacking, however, and many fundamental questions pertaining to precise lymphatic mapping remain unanswered. Whether the sentinel node concept is of general relevance or whether it is applicable in only a few organs remains to be determined. This book offers intensive discussion of the concept from methodological and tu mor biological viewpoints. World-renowned experts with long term involvement in related basic and clinical research provide the reader with a broad survey of actual knowledge together with a critical appraisal of recent and future developments. We sincerely hope this book succeeds in providing an outlook as a reference for all clinicians on future prospects and serving and researchers in this extremely important field.
| Author | : Peter M. Schlag |
| Publisher | : |
| Total Pages | : |
| Release | : 2000 |
| Genre | : |
| ISBN | : |
Download Lymphatic metastasis and sentinel lymphonodectomy Book in PDF, ePub and Kindle
| Author | : Alfred Schauer |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 572 |
| Release | : 2005-10-28 |
| Genre | : Medical |
| ISBN | : 3540263934 |
Download The Sentinel Lymph Node Concept Book in PDF, ePub and Kindle
The practical application of the sentinel node concept is evaluated in this book. The concept is analyzed for breast cancer, malignant melanoma, tumors of the face, oropharynx, lung, gastrointestinal and urogenital tract. The first part of the book describes the function and use of the nuclear medicine equipment, the tracers used, colloid solutions and modern developments in histological and immunohistochemical lymph node investigations, as well as possible pitfalls. In the second part, specific tumor-related problems are described.
| Author | : Hiram S. Cody |
| Publisher | : CRC Press |
| Total Pages | : 300 |
| Release | : 2001-11-08 |
| Genre | : Medical |
| ISBN | : 9781841840345 |
Download Sentinel Lymph Node Biopsy Book in PDF, ePub and Kindle
An intuitive, ingenious and powerful technique, sentinel lymph node biopsy has entered clinical practice with astonishing rapidity and now represents a new standard of care for melanoma and breast cancer patients, while showing great promise for the treatment of urologic, colorectal, gynecologic, and head and neck cancers. This text, written by international experts in the technique, provides a clear and comprehensive guide, presenting a detailed overview and discussing the various mapping techniques available and how these are applied in a number of leading institutions. This essential resource for surgical onocologists, pathologists, and specialists in nuclear medicine will also provide key information for those planning to start a sentinel lymph node program.
| Author | : S. David Nathanson |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2022 |
| Genre | : Cancer |
| ISBN | : 9783030930851 |
Download Cancer Metastasis Through the Lymphovascular System Book in PDF, ePub and Kindle
This textbook describes in detail the process of cancer metastasis from a single cell in the primary site through its arduous journey to the sentinel lymph node as the main gateway and beyond to distant sites. The most up-to-date knowledge on key topics in the molecular biology, diagnosis, and treatment of metastatic cancer is highlighted by a large panel of experts. The book begins with a comprehensive overview of the genetic and molecular mechanisms that promote or inhibit cancer metastasis through lymphatic pathways to lymph nodes or through vascular pathways to distant sites, providing the reader with an essential basic knowledge. This is followed by further details on the role of the immune system within the primary tumor and the lymph node and the importance of the microenvironment at the metastatic site. The role of the sentinel lymph node in cancer metastasis is emphasized. Special attention is also given to state-of-the-art imaging techniques for the detection of early-stage cancer and cancer metastases, as well as the use of liquid biopsies in sarcoma, prostate, gastrointestinal, and lung cancer. Clinical patterns of malignant tumors arising in different organ systems are compared, described, and discussed with the goal of determining what similarities and/or differences exist. The book concludes with a detailed discussion of surgical intervention, radiation, and systemic therapy of primary and metastatic cancer, and briefly previews several emerging topics, such as the latest findings on personalized cancer therapy, cancer stem cells, unique molecular mechanisms of virus-induced cancer, the impact of the microbiome on cancer metastasis and the application of artificial intelligence in cancer metastasis research. By providing fundamental knowledge of the biological and clinical aspects of cancer metastasis, this book will be an important reference for cancer researchers, clinical oncologists, teachers, and students. Written by experts in the field, each chapter includes a summary of the chapter's key points and open-ended questions that address pressing issues in the field and encourage the reader to consider future directions. .
| Author | : Mandi Murph |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 414 |
| Release | : 2015-04-01 |
| Genre | : Medical |
| ISBN | : 9535120360 |
Download Melanoma Book in PDF, ePub and Kindle
Melanoma - Current Clinical Management and Future Therapeutics serves as an advanced course in melanoma or an addendum to further polish expertise. Sections of the book include a thorough introduction on epidemiology and disease, the current surgical management of melanoma and lymph node dissection, immunotherapy along with drug toxicities and emerging research topics, like RAGE and autotaxin, that have potential therapeutic applications. The chapters in this book explore the most common subtype of melanoma, cutaneous disease, as well as a rare form, acral lentiginous melanoma and even canine tumors. Experts from around the globe contributed chapters, most of which have visual illustrations to depict aspects of disease management and therapy, allowing readers to grasp the advanced concepts presented.
| Author | : Giuliano Mariani |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 319 |
| Release | : 2010-05-10 |
| Genre | : Medical |
| ISBN | : 0387383271 |
Download Radioguided Surgery Book in PDF, ePub and Kindle
This multidisciplinary textbook is designed to be the standard on the subject and is geared for use by physicians who are involved in the care and/or diagnosis of cancer patients. Comprehensive coverage is provided on all aspects of radioguided surgery. Practical information is readily accessible and throughout there is an emphasis on improved decision making. Tables present the indications, performance, and interpretation of procedures at a glance. A wealth of illustrations, including a full-color insert, enhances the application of new concepts.
| Author | : Stanley P. L. Leong |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 125 |
| Release | : 2006-04-18 |
| Genre | : Medical |
| ISBN | : 0306478226 |
Download Atlas of Selective Sentinel Lymphadenectomy for Melanoma, Breast Cancer and Colon Cancer Book in PDF, ePub and Kindle
Atlas of Selective Lymphadenectomy for Melanoma, Breast Cancer and Colon Cancer emphasizes a multidisciplinary approach combining the experiences of a nuclear medicine physician, surgeon, and pathologist. This is an important reference also for researchers and clinicians who want to become familiar with sentinel lymph node mapping. The underlying thesis in solid tumor biology is that metastasis in general starts in an orderly progression with lymphatic spread first to the sentinel lymph node (SLN) in the nearest lymph node basin. Therefore, the logical approach is to harvest that specific SLN for thorough analysis.
| Author | : Vincent J. Hearing |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 673 |
| Release | : 2007-11-05 |
| Genre | : Medical |
| ISBN | : 159259994X |
Download From Melanocytes to Melanoma Book in PDF, ePub and Kindle
Leading researchers and clinicians join forces to explain how malignant melanoma develops from its benign precursor cell type. The authors focus on the molecular mechanisms involved in melanogenesis, in the malignant transformation of melanocytes, and in the further progression of primary melanomas into invasive and metastatic melanomas. They also review recent advances in our understanding of the basic biology of melanocytes and the development, migration, and differentiation of melanoblasts into melanocytes. The book provides an up-to-date understanding of the progressive mechanisms of oncological development in malignant melanoma, a likely model of malignant progress for other types of cancer, and the ongoing development of novel therapeutics.
| Author | : Cumali Aktolun |
| Publisher | : Lippincott Williams & Wilkins |
| Total Pages | : 1964 |
| Release | : 2014-09-04 |
| Genre | : Medical |
| ISBN | : 146988349X |
Download Nuclear Oncology Book in PDF, ePub and Kindle
Nuclear Oncology a contemporary narrative of the role of nuclear medicine in oncology with an emphasis on SPECT/CT and PET/CT with additional comments when appropriate on the potential application of PET/MR and to a lesser degree, targeted radionuclide therapy. This book focuses on the use of radionuclides in the diagnosis and treatment of malignant diseases. It describes relevant approved and investigational clinical applications, instrumentation & technology, chemistry and practical clinical issues in nuclear oncology. The basic science and current research topics of nuclear oncology are addressed in separate chapters. Nuclear medicine has become an essential component to all phases of the management of the patient with a malignant tumor and in some cases, even benign neoplasms. The standard of practice for many tumors requires PET/CT imaging at various stages of diagnosis and management. In addition to clinical applications, ongoing investigational efforts, which more and more involve multi-institutional protocols, are also presented. Features: • Focuses on the use of radionuclides in the diagnosis and treatment of malignant diseases • Emphasizes SPECT/CT and PET/CT with additional emphasis on the potential application of PET/MR • Describes relevant approved and investigational clinical applications, instrumentation & technology, chemistry and practical clinical issues in nuclear oncology
