Long Non Coding Rnas In Human Disease PDF Download
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Author | : Kevin V. Morris |
Publisher | : Springer |
Total Pages | : 267 |
Release | : 2016-04-13 |
Genre | : Medical |
ISBN | : 3319239074 |
Download Long Non-coding RNAs in Human Disease Book in PDF, ePub and Kindle
This volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing. The role of lncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, past retroelements integrated within the human genome, as well as the role these pseudogene-derived lncRNAs play in cancer development are discussed in detail. Further, the book examines the function of lncRNAs in diseases such as diabetes, in smooth muscle formation, and in the modulation of nuclear receptors, as well as in connection with perspectives on the development of personalized therapeutics. It offers an appealing and insightful resource for scientists and clinicians alike.
Author | : Yujing Li |
Publisher | : Frontiers Media SA |
Total Pages | : 346 |
Release | : 2020-07-08 |
Genre | : |
ISBN | : 2889638324 |
Download Non-Coding RNAs and Human Diseases Book in PDF, ePub and Kindle
Author | : Jing Zhang |
Publisher | : Frontiers Media SA |
Total Pages | : 325 |
Release | : 2023-04-14 |
Genre | : Science |
ISBN | : 2832520804 |
Download RNA modification and non-coding RNAs in human disease Book in PDF, ePub and Kindle
Author | : Lütfi Tutar |
Publisher | : BoD – Books on Demand |
Total Pages | : 150 |
Release | : 2020-03-04 |
Genre | : Medical |
ISBN | : 1789856558 |
Download Non-Coding RNAs Book in PDF, ePub and Kindle
Noncoding RNAs (ncRNAs) are an attractive research field in the RNA world. ncRNAs play important roles in regulating gene expression in animals, plants, and various human diseases. It is clear that current and further research on ncRNAs will change our knowledge of the nature of genome composition by editing previous dogmas. This book provides an overview of current knowledge on ncRNA research by dealing with miRNA and ncRNA-related human diseases, plant miRNA markers, and the roles of lncRNAs in cancer and epigenetics.
Author | : Santosh Kumar Upadhyay |
Publisher | : Academic Press |
Total Pages | : 390 |
Release | : 2020-11-13 |
Genre | : Science |
ISBN | : 0128214635 |
Download Long Noncoding RNAs in Plants Book in PDF, ePub and Kindle
The growth of human population has increased the demand for improved yield and quality of crops and horticultural plants. However, plant productivity continues to be threatened by stresses such as heat, cold, drought, heavy metals, UV radiations, bacterial and fungal pathogens, and insect pests. Long noncoding RNAs are associated with various developmental pathways, regulatory systems, abiotic and biotic stress responses and signaling, and can provide an alternative strategy for stress management in plants. Long Noncoding RNAs in Plants: Roles in development and stress provides the most recent advances in LncRNAs, including identification, characterization, and their potential applications and uses. Introductory chapters include the basic features and brief history of development of lncRNAs studies in plants. The book then provides the knowledge about the lncRNAs in various important agricultural and horticultural crops such as cereals, legumes, fruits, vegetables, and fiber crop cotton, and their roles and applications in abiotic and biotic stress management. Includes the latest advances and research in long noncoding RNAs in plants Provides alternative strategies for abiotic and biotic stress management in horticultural plants and agricultural crops Focuses on the application and uses of long noncoding RNAs
Author | : Syed Mudasir Andrabi |
Publisher | : Cambridge Scholars Publishing |
Total Pages | : 201 |
Release | : 2020-09-03 |
Genre | : Science |
ISBN | : 1527559106 |
Download Long Non-Coding RNA Book in PDF, ePub and Kindle
Long non-coding RNAs (LncRNAs) were originally regarded as “noise” in the genome due to their lack of protein-encoding capacity. However, their roles are now understood to cover various biological functions like gene regulation, cell proliferation, survival, differentiation, and chromatin remodeling. As an emerging group of non-coding RNA molecules, LncRNAs are involved in diverse diseases like cancer, cardiovascular, autoimmune, hormonal disorders, neurodegeneration, and infection, among others. However, knowledge of the mechanisms by which they act is still ambiguous. As such, this book meets the essential need for a textbook dedicated to this topic and provides a comprehensive and captivating account of lncRNA research.
Author | : |
Publisher | : Academic Press |
Total Pages | : 444 |
Release | : 2020-08-19 |
Genre | : Medical |
ISBN | : 0128171944 |
Download RNA-Based Regulation in Human Health and Disease Book in PDF, ePub and Kindle
RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA-binding proteins, alternative splicing, RNA editing, antisense transcripts and RNA G-quadruplexes), dynamic aspects of RNA regulation modulating physiological homeostasis (aging), role of RNA beyond humans, tools and technologies for RNA research (wet lab and computational) and future prospects for RNA-based diagnostics and therapeutics. One of the core strengths of the book includes spectrum of disease-specific chapters from experts in the field highlighting RNA-based regulation in metabolic & neurodegenerative disorders, cancer, inflammatory disease, viral and bacterial infections. We hope the book helps researchers, students and clinicians appreciate the role of RNA-based regulation in genome regulation, aiding the development of useful biomarkers for prognosis, diagnosis, and novel RNA-based therapeutics. Comprehensive information of non-canonical RNA-based genome regulation modulating human health and disease Defines RNA classes with special emphasis on unexplored world of noncoding RNA at different hierarchies Disease specific role of RNA - causal, prognostic, diagnostic and therapeutic Features contributions from leading experts in the field
Author | : Alfons Navarro |
Publisher | : Humana |
Total Pages | : 0 |
Release | : 2022-06-25 |
Genre | : Medical |
ISBN | : 9781071615836 |
Download Long Non-Coding RNAs in Cancer Book in PDF, ePub and Kindle
This volume presents techniques needed for the study of long non-coding RNAs (lncRNAs) in cancer from their identification to functional characterization. Chapters guide readers through identification of lncRNA expression signatures in cancer tissue or liquid biopsies by RNAseq, single Cell RNAseq, Phospho RNAseq or Nanopore Sequencing techniques; validation of lncRNA signatures by Real time PCR, digital PCR or in situ hybridization; and functional analysis by siRNA or CRISPR based methods for lncRNA silencing or overexpression. Lipid based nanoparticles for delivery of siRNAs in vivo, lncRNA-protein interactions, viral lncRNAs and circRNAs are also treated in this volume. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Long Non-Coding RNAs in Cancer aims to provide a collection of laboratory protocols, bioinformatic pipelines, and review chapters to further research in this vital field.
Author | : Lin Zhang |
Publisher | : Humana |
Total Pages | : 0 |
Release | : 2022-09-04 |
Genre | : Medical |
ISBN | : 9781071616994 |
Download Long Non-Coding RNAs Book in PDF, ePub and Kindle
This second edition provides a broad spectrum of methods used in long non-coding RNAs (lncRNA) research, ranging from computational annotation of lncRNA genes to molecular and cellular analyses of the function of individual lncRNA. Chapters guide readers through studies used to circular RNAs, RNA splicing, and findings on lncRNA in human diseases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Long Non-Coding RNAs: Methods and Protocols,Second Edition aims to ensure successful results in the further study of this vital field.
Author | : M.R.S. Rao |
Publisher | : Springer |
Total Pages | : 336 |
Release | : 2017-08-16 |
Genre | : Medical |
ISBN | : 9811052034 |
Download Long Non Coding RNA Biology Book in PDF, ePub and Kindle
This contributed volume offers a comprehensive and detailed overview of the various aspects of long non-coding RNAs and discusses their emerging significance. Written by leading experts in the field, it motivates young researchers around the globe, and offers graduate and postgraduate students fascinating insights into genes and their regulation in eukaryotes and higher organisms.