Long Non Coding Rnas PDF Download
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| Author | : M.R.S. Rao |
| Publisher | : Springer |
| Total Pages | : 323 |
| Release | : 2017-08-16 |
| Genre | : Medical |
| ISBN | : 9811052034 |
Download Long Non Coding RNA Biology Book in PDF, ePub and Kindle
This contributed volume offers a comprehensive and detailed overview of the various aspects of long non-coding RNAs and discusses their emerging significance. Written by leading experts in the field, it motivates young researchers around the globe, and offers graduate and postgraduate students fascinating insights into genes and their regulation in eukaryotes and higher organisms.
| Author | : Santosh Kumar Upadhyay |
| Publisher | : Academic Press |
| Total Pages | : 390 |
| Release | : 2020-11-13 |
| Genre | : Science |
| ISBN | : 0128214635 |
Download Long Noncoding RNAs in Plants Book in PDF, ePub and Kindle
The growth of human population has increased the demand for improved yield and quality of crops and horticultural plants. However, plant productivity continues to be threatened by stresses such as heat, cold, drought, heavy metals, UV radiations, bacterial and fungal pathogens, and insect pests. Long noncoding RNAs are associated with various developmental pathways, regulatory systems, abiotic and biotic stress responses and signaling, and can provide an alternative strategy for stress management in plants. Long Noncoding RNAs in Plants: Roles in development and stress provides the most recent advances in LncRNAs, including identification, characterization, and their potential applications and uses. Introductory chapters include the basic features and brief history of development of lncRNAs studies in plants. The book then provides the knowledge about the lncRNAs in various important agricultural and horticultural crops such as cereals, legumes, fruits, vegetables, and fiber crop cotton, and their roles and applications in abiotic and biotic stress management. Includes the latest advances and research in long noncoding RNAs in plants Provides alternative strategies for abiotic and biotic stress management in horticultural plants and agricultural crops Focuses on the application and uses of long noncoding RNAs
| Author | : Muller Fabbri |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 287 |
| Release | : 2013-10-28 |
| Genre | : Medical |
| ISBN | : 1461484448 |
Download Non-coding RNAs and Cancer Book in PDF, ePub and Kindle
The discovery of microRNAs and its role as gene expression regulators in human carcinogenesis represents one of the most important scientific achievements of the last decade. More recently, other non-coding RNAs have been discovered and its implications in cancer are emerging as well, suggesting a broader than anticipated involvement of the non-coding genome in cancer. Moreover, completely new and unexpected functions for microRNAs are being revealed, leading to the identification of new anticancer molecular targets. This book represents a comprehensive guide on non-coding RNAs and cancer, spanning from its role as cancer biomarkers, to providing the most useful bioinformatic tools, to presenting some of the most relevant discoveries, which indicates how these fascinating molecules act as fine orchestrators of cancer biology.
| Author | : Lesley J. Collins |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 297 |
| Release | : 2011-09-15 |
| Genre | : Medical |
| ISBN | : 1461403324 |
Download RNA Infrastructure and Networks Book in PDF, ePub and Kindle
RNAs form complexes with proteins and other RNAs. The RNA‐infrastructure represents the spatiotemporal interaction of these proteins and RNAs in a cell‐wide network. RNA Infrastructure and Networks brings together these ideas to illustrate the scope of RNA‐based biology, and how connecting RNA mechanisms is a powerful tool to investigate regulatory pathways. This book is but a taste of the wide range of RNA‐based mechanisms that connect in the RNA infrastructure.
| Author | : Ahmad M. Khalil |
| Publisher | : Springer |
| Total Pages | : 187 |
| Release | : 2019-06-06 |
| Genre | : Medical |
| ISBN | : 3030170861 |
Download Molecular Biology of Long Non-coding RNAs Book in PDF, ePub and Kindle
This second edition shows how long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity. So, while their function is not entirely clear, they may serve as key organizers of protein complexes that allow for higher order regulatory events. Advances in the field also include better characterization of human long non-coding RNAs, novel insights into their roles in human development and disease, their diverse mechanisms of action and novel technologies to study them.
| Author | : Kevin V. Morris |
| Publisher | : Springer |
| Total Pages | : 267 |
| Release | : 2016-04-13 |
| Genre | : Medical |
| ISBN | : 3319239074 |
Download Long Non-coding RNAs in Human Disease Book in PDF, ePub and Kindle
This volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing. The role of lncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, past retroelements integrated within the human genome, as well as the role these pseudogene-derived lncRNAs play in cancer development are discussed in detail. Further, the book examines the function of lncRNAs in diseases such as diabetes, in smooth muscle formation, and in the modulation of nuclear receptors, as well as in connection with perspectives on the development of personalized therapeutics. It offers an appealing and insightful resource for scientists and clinicians alike.
| Author | : Ahmad Khalil |
| Publisher | : Springer |
| Total Pages | : 0 |
| Release | : 2013-09-20 |
| Genre | : Medical |
| ISBN | : 9781461486206 |
Download Molecular Biology of Long Non-coding RNAs Book in PDF, ePub and Kindle
Long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity. So, while their function is not entirely clear, they may serve as key organizers of protein complexes that allow for higher order regulatory events. Discovering these functions has been the result of intense research done of the last few years, and lncRNA research has had several critical developments during that time. This book will consolidate these ideas and models to better examine the most important issues in lncRNA biology. This will include critical studies that have led to the discovery and annotation of lncRNAs in numerous species, and the molecular mechanisms for a few lncRNA that have begun to emerge.
| Author | : Adam Williams |
| Publisher | : Frontiers Media SA |
| Total Pages | : 68 |
| Release | : 2021-06-29 |
| Genre | : Medical |
| ISBN | : 2889669173 |
Download Long Non-Coding RNAs and Immunity Book in PDF, ePub and Kindle
We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). We hereby state publicly that the IUIS has had no editorial input in articles included in this Research Topic, thus ensuring that all aspects of this Research Topic are evaluated objectively, unbiased by any specific policy or opinion of the IUIS.
| Author | : Jayprokas Chakrabarti |
| Publisher | : Academic Press |
| Total Pages | : 576 |
| Release | : 2017-10-13 |
| Genre | : Medical |
| ISBN | : 0128134372 |
Download Cancer and Noncoding RNAs Book in PDF, ePub and Kindle
Cancer and Noncoding RNAs offers an in-depth exploration of noncoding RNAs and their role in epigenetic regulation of complex human disease, most notably cancer. In addition to examining microRNAs, this volume provides a unique evaluation of more recently profiled noncoding RNAs now implicated in carcinogenesis, including lncRNAs, piRNAs, circRNAs, and tRNAs, identifying differences in function between these noncoding RNAs and how they interact with the rest of the epigenome. A broad range of chapters from experts in the field detail epigenetic regulation of various cancer types, along with recent next generation sequencing technologies, genome-wide association studies (GWAS) and bioinformatics approaches. This book will help researchers in genomic medicine and cancer biology better understand the role of noncoding RNAs in epigenetics, aiding in the development of useful biomarkers for diagnosis, prognosis and new RNA-based disease therapies. Provides a comprehensive analysis of noncoding RNAs implicated in epigenetic regulation of gene expression and chromatin dynamics Educates researchers and graduate students by highlighting, in addition to miRNAs, a range of noncoding RNAs newly associated with carcinogenesis Applies current knowledge of noncoding RNAs and epigenomics towards developing cancer and RNA-based disease therapies Features contributions by leading experts in the field
| Author | : Durdica Ugarkovic |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 216 |
| Release | : 2011-02-01 |
| Genre | : Science |
| ISBN | : 3642165028 |
Download Long Non-Coding RNAs Book in PDF, ePub and Kindle
Long non-coding RNAs (lncRNAs), tentatively defined as ncRNAs of more than two hundred nucleotides in length, are characterized by the complexity and diversity of their sequences and mechanisms of action. Based on genome-wide studies, more than 3,300 of them exist, but to date only the limited number of functional lncRNAs have been identified and characterized. Nonetheless, lncRNAs have emerged as key molecules involved in the control of transcriptional and posttranscriptional gene regulatory pathways. They take part in the recruitment of chromatin modifying complexes and regulate splicing, localization, stability and translation of the target mRNAs. This book provides an overview of the rapidly advancing field of long ncRNAs, describing the epigenetic and non-epigenetic mechanisms by which they regulate various biological functions in model systems, from yeast to mammals. The role of ncRNAs in sex chromosome dosage compensation in flies and mammals is described, as well as their role in centromere and telomere biology. Long non-coding RNAs involved in environmental stress response and development are presented and their mechanisms of action discussed.
