Ligand And Electronically Induced Activation Patterns In Myenteric Neuronal Networks PDF Download
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Author | : Raf Bisschops |
Publisher | : Leuven University Press |
Total Pages | : 160 |
Release | : 2005 |
Genre | : Autonomic nervous system |
ISBN | : 9789058674555 |
Download Ligand and Electronically Induced Activation Patterns in Myenteric Neuronal Networks Book in PDF, ePub and Kindle
Gastrointestinal motility regulated by hormonal, myogenic and neuronal mechanisms. The neuronal control consists of two elements: on the one hand the extrinsic innervation by para- and ortho-sympathetic nerve fibres and on the other hand intrinsic intrinsic innervation by the enteric nervous system (ENS). The myenteric plexus as part of the ENS, is to a great extent involved in the control of gastrointestinal motility. The guinea-pig myenteric plexus has been the subject of intense research over the last three decades, resulting in a better understanding of gastrointestinal physiology and motility. The ENS comprises a large diversity of neurons. Current classification schemes of enteric neurons are mainly based on the data obtained from classical electrophysical experiments, immunohistochemistry and retrograde labeling techniques. Electrophysiological recordings give real-time information concerning the electrical activity of one impaled myenteric neuron (S/AH type neurons), but this information is mostly limited to a single neuron. Immunohistochemical staining for different neurotransmitters or different functionally relevant proteins provides information about an activity due to intrinsic technical limitations of fixation techniques.
Author | : Katleen Vantieghem |
Publisher | : Leuven University Press |
Total Pages | : 146 |
Release | : 2006 |
Genre | : Keratinocytes |
ISBN | : 9789058675613 |
Download Photoproduction of Vitamin D3 and Activation into 1a,25-Dihydroxyvitamin D3 in Human Epiderman Keratinocytes, Dermal Fibroblasts and Other Cells Book in PDF, ePub and Kindle
Author | : Maarten Leyssen |
Publisher | : Leuven University Press |
Total Pages | : 142 |
Release | : 2006 |
Genre | : Axons |
ISBN | : 9789058675682 |
Download Axon Growth, Injury and Regeneration in the Fly Brain Book in PDF, ePub and Kindle
Author | : Karel Allegaert |
Publisher | : Leuven University Press |
Total Pages | : 168 |
Release | : 2005 |
Genre | : Pain in infants |
ISBN | : 9789058675057 |
Download Neonatal Analgesia Book in PDF, ePub and Kindle
Author | : An van Nieuwenhuyse |
Publisher | : Leuven University Press |
Total Pages | : 168 |
Release | : 2005 |
Genre | : Back |
ISBN | : 9789058674951 |
Download A Prospective Study of Risk Factors for Low Back Disorders in Occupational Settings Book in PDF, ePub and Kindle
Author | : Nico Hendrickx |
Publisher | : Leuven University Press |
Total Pages | : 154 |
Release | : 2006 |
Genre | : Cyclooxygenase 2 |
ISBN | : 9789058675286 |
Download Mechanism and Role of Cyclooxygenase-2 Up-Regulation by Photodynamic Therapy Book in PDF, ePub and Kindle
Author | : Jos Tournoy |
Publisher | : Leuven University Press |
Total Pages | : 124 |
Release | : 2006 |
Genre | : Alzheimer's disease |
ISBN | : 9789058675262 |
Download Physiological Study of Presenilins and Baces, Two Proteases Involved in the Pathogenesis of Alzheimer's Disease Book in PDF, ePub and Kindle
Author | : Bert Bammens |
Publisher | : Leuven University Press |
Total Pages | : 276 |
Release | : 2005 |
Genre | : Cresol |
ISBN | : 9789058674821 |
Download The Protein-bound Solute P-cresol Book in PDF, ePub and Kindle
Author | : Leifu Jiang |
Publisher | : Leuven University Press |
Total Pages | : 128 |
Release | : 2006-09 |
Genre | : |
ISBN | : 9789058675422 |
Download Role of Nitric Oxide Synthase in the Regulation of Pulmonary Vascular Tone Book in PDF, ePub and Kindle
Author | : Ellen De Schrijver |
Publisher | : Leuven University Press |
Total Pages | : 158 |
Release | : 2005 |
Genre | : Antimitotic agents |
ISBN | : 9789058674562 |
Download Fatty Acid Synthase Book in PDF, ePub and Kindle
Fatty acid synthase (FAS) is a key lipogenic enzyme catalyzing the terminal steps in the synthesis of fatty acids. In the majority of normal tissues, FAS expression is low. In many human cancers, however, including cancer of the prostate, FAS expression and FAS activity are very high. As shown in the laboratory, overexpression of FAS in tumor cells is part of a more general and coordinate upregulation of multiple lipogenic genes caused, at least in part, by activation of sterol regulatory element binding proteins (SREBPs), transcription factors that play a key role in cellular lipid homeostasis. The mechanisms underlying the activation of the SREBP pathway and the increase in lipogenesis in tumor cells as well as the ultimate biological significance of this phenomenon remain poorly understood. Nonetheless there is evidence that overexpression of lipogenic genes occurs early in tumor development and that the degree of overexpression correlates with increasing tumor grade. Moreover, a number of studies suggest that inhibition of FAS selectively reduces proliferation of tumor cells and causes apoptosis, implying that FAS and other lipogenic enzymes may constitute interesting targets for antineoplastic therapy.