Krug Dna I Noci PDF Download
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| Author | : Richard D. Granstein |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 248 |
| Release | : 2009-02-08 |
| Genre | : Medical |
| ISBN | : 3540359893 |
Download Neuroimmunology of the Skin Book in PDF, ePub and Kindle
Much anecdotal information has suggested an influence of psychology and the nervous system on immunity within the skin and the expression of inflammatory skin disorders. Recent years have seen an explosion of knowledge providing a scientific basis for important regulatory interactions between the nervous system, the endocrine system and the immune system within the skin. The results of recent investigations have important implications, not only for an understanding of cutaneous immunity, but also for the development of novel treatments for diseases involving abnormal inflammation or immune reactivity within the skin. This book provides a comprehensive and interdisciplinary review of the molecular biology, cell biology, biochemistry and clinical aspects of nervous system–immune system interactions within the skin. It includes contributions from leading world experts in these areas. The contents are relevant to both investigators and clinicians interested in the skin, its functions and its disorders.
| Author | : Vincenzo Guidetti |
| Publisher | : Springer |
| Total Pages | : 246 |
| Release | : 2017-09-01 |
| Genre | : Medical |
| ISBN | : 3319547267 |
Download Headache and Comorbidities in Childhood and Adolescence Book in PDF, ePub and Kindle
This book aims to provide clinicians and other practitioners and professionals with up-to-date information on how to evaluate and manage headaches in children and adolescents, highlighting the most recent recommendations. Unlike in other books on the subject, detailed attention is devoted to the various comorbidities commonly associated with headache, including psychiatric comorbidities such as depression, anxiety, attention deficit hyperactivity disorder, and learning disabilities and medical conditions such as epilepsy, vascular disorders, brain tumors, atopic disease, and obesity. The intimate link between these conditions and headache is explained with a view to enabling the reader to recognize their presence and, on that basis, to institute the most effective pharmacological or non-pharmacological treatment strategy. Moreover, knowledge of the comorbidities associated with headache will help readers to understand more fully the causes of this serious disorder and also its consequences, e.g., for school performance, relationships, and daily activities. The authors are all international experts who care for children with headache or the other described disorders.
| Author | : Jason B. Wolf |
| Publisher | : Oxford University Press, USA |
| Total Pages | : 348 |
| Release | : 2000 |
| Genre | : Science |
| ISBN | : 9780195128062 |
Download Epistasis and the Evolutionary Process Book in PDF, ePub and Kindle
Over the last two decades, research into epistasis has seen explosive growth and has moved the focus of research in evolutionary genetics from a traditional additive approach. We now know the effects of genes are rarely independent, and to reach a fuller understanding of the process of evolution we need to look at gene interactions as well as gene-environment interactions. This book is an overview of non-additive evolutionary genetics, integrating all work to date on all levels of evolutionary investigation of the importance of epistasis in the evolutionary process in general. It includes a historical perspective on this emerging field, in-depth discussion of terminology, discussions of the effects of epistasis at several different levels of biological organization and combinations of theoretical and experimental approaches to analysis.
| Author | : Beverley Greenwood-Van Meerveld |
| Publisher | : Springer |
| Total Pages | : 446 |
| Release | : 2017-04-19 |
| Genre | : Medical |
| ISBN | : 3319563602 |
Download Gastrointestinal Pharmacology Book in PDF, ePub and Kindle
This volume aims to connect current ideas and concepts about GI disorders with the search for novel therapeutics. Towards this goal, authors provide a timely state-of-the-art overview of the GI tract in health and disease, current treatment approaches and ongoing developments in drug discovery, and their potential for the better treatment of patients with GI disorders.
| Author | : Nikolaos Labrou |
| Publisher | : Springer Nature |
| Total Pages | : 388 |
| Release | : 2019-09-03 |
| Genre | : Science |
| ISBN | : 981137709X |
Download Therapeutic Enzymes: Function and Clinical Implications Book in PDF, ePub and Kindle
Therapeutic enzymes exhibit fascinating features and opportunities, and represent a significant and promising subcategory of modern biopharmaceuticals for the treatment of several severe diseases. Research and drug developments efforts and the advancements in biotechnology over the past twenty years have greatly assisted the introduction of efficient and safe enzyme-based therapies for a range of both rare and common disorders. The introduction and regulatory approval of twenty different recombinant enzymes has enabled effective enzyme-replacement therapy. This volume aims to overview these therapeutic enzymes, focusing in particular on more recently approved enzymes produced by recombinant DNA technology. This volume is composed of four sections. Section 1 provides an overview of the production process and biochemical characterization of therapeutic enzymes, while Section 2 focuses upon the engineering strategies and delivery methods of therapeutic enzymes. Section 3 highlights the clinical applications of approved therapeutic enzymes, including aspects on their structure, indications and mechanisms of action. Together with information on these mechanisms, safety and immunogenicity issues and various adverse events of the recombinant enzymes used for therapy are discussed. Section 4, provides discussion on the prospective and future developments of new therapeutic enzymes. This book is aimed at academics, researchers and students undertaking advanced undergraduate/postgraduate programs in the biopharmaceutical/biotechnology area who wish to gain a comprehensive understanding of enzyme-based therapeutic molecules.
| Author | : Robert Burns |
| Publisher | : |
| Total Pages | : 878 |
| Release | : 1913 |
| Genre | : |
| ISBN | : |
Download Songs & Poems Book in PDF, ePub and Kindle
| Author | : Marc G. Jeschke |
| Publisher | : Springer Nature |
| Total Pages | : 217 |
| Release | : 2020-12-21 |
| Genre | : Medical |
| ISBN | : 3030391930 |
Download Burn Care and Treatment Book in PDF, ePub and Kindle
The second edition of this practical guide offers a comprehensive summary of the most important and most immediate therapeutic approaches in the assessment and treatment of burn injuries. Taking into account age-specific needs in pediatric, adult, and elderly burn patients, several chapters on key issues – such as pre-hospital treatment, wound care and infection control, burn nursing, critical care, burn reconstructive surgery and rehabilitation for burn victims – have now been updated. In addition, the book has been supplemented with the latest information on fluid resuscitation, organ support for burn patients, necrotizing soft tissue infections, and TEN/SJS. Written in a concise manner, the updated edition of this book provides essential guidelines for optimal care to improve patient outcomes, and thus will be a valuable reference resource for physicians, surgeons, residents, nurses, and other burn care providers.
| Author | : Ceana H. Nezhat |
| Publisher | : Springer |
| Total Pages | : 439 |
| Release | : 2018-10-29 |
| Genre | : Medical |
| ISBN | : 3319907522 |
Download Non-Obstetric Surgery During Pregnancy Book in PDF, ePub and Kindle
As minimally invasive surgical techniques evolve, the outlook for patients continues to brighten. This is also true for pregnant women experiencing conditions requiring surgical intervention during gestation. A physician’s ability to identify potential risk factors in pregnant patients that present pre-op directly corresponds with their success in monitoring patients in post-op for adverse obstetric outcomes from non-obstetric surgeries. The utilization of laparoscopic techniques during surgery for pregnant patients has decreased the risk of fetal complications and increased the positive outlook for the duration of the pregnancy. This text is designed to present a minimally invasive approach to surgery that is non-obstetrics related and to educate readers on the potential risk factors and negative outcomes on pregnant patients following non-obstetric surgery. The various sections of this book will address issues faced by surgeons who undertake the task of operating on the pregnant patient. When performing non-obstetric surgery on a pregnant patient the ability to identify possible risk factors for adverse obstetric outcomes is important. Risk factors can be maternal-, surgical-, obstetrical-, or disease-associated. Common adverse obstetric outcomes following non-obstetric surgery include preterm delivery, preterm labor without preterm delivery, and miscarriage. Fetal well-being is an additional risk-benefit factor to be considered when weighing options before conducting non-obstetric surgeries on pregnant patients. This book will provide physicians with the knowledge and tools to identify common risk factors and successfully apply evidence-based risk reduction. To date, no comprehensive resource is available for non-obstetric surgery during pregnancy. Types of pregnancies, potential complications, proper use of anesthesia, types of risk factors (maternal-, surgical-, obstetrical-, and disease-associated), etc. will be thoroughly explained and depicted within these pages. All chapters will be written by subject matter experts in their fields. All information communicated will be comprised of the most currently available knowledge
| Author | : Arkadi Vigalok |
| Publisher | : Springer |
| Total Pages | : 198 |
| Release | : 2010-06-30 |
| Genre | : Science |
| ISBN | : 3642120733 |
Download C-X Bond Formation Book in PDF, ePub and Kindle
Contents: Kilian Muñiz: Transition Metal Catalyzed Electrophilic Halogenation of C-H bonds in alpha-Position to Carbonyl Groups; Arkadi Vigalok * and Ariela W Kaspi: Late Transition Metal-Mediated Formation of Carbon-Halogen Bonds; Paul Bichler and Jennifer A. Love*: Organometallic Approaches to Carbon-Sulfur Bond Formation; David S. Glueck: Recent Advances in Metal-Catalyzed C-P Bond Formation; Andrei N. Vedernikov: C-O Reductive Elimination from High Valent Pt and Pd Centers; Lukas Hintermann: Recent Developments in Metal-Catalyzed Additions of Oxygen Nucleophiles to Alkenes and Alkynes; Moris S. Eisen: Catalytic C-N, C-O and C-S bond formation promoted by organoactinide complexes.
| Author | : Mauro Varotto |
| Publisher | : Springer |
| Total Pages | : 357 |
| Release | : 2018-12-06 |
| Genre | : Technology & Engineering |
| ISBN | : 3319968157 |
Download World Terraced Landscapes: History, Environment, Quality of Life Book in PDF, ePub and Kindle
This volume collects the best scientific contribution presented in the 3rd World Conference on Terraced Landscapes held in Italy from 6th to 15th October 2016, offering a deep and multifaceted insight into the remarkable heritage of terraced landscapes in Italy, in Europe and in the World (America, Asia, Australia). It consists of 2 parts: a geographical overview on some of the most important terraced systems in the world (1st part), and a multidisciplinary approach that aims to promote a multifunctional vision of terraces, underlining how these landscapes meet different needs: cultural and historical values, environmental and hydrogeological functions, quality and variety of food, community empowerment and sustainable development (2nd part). The volume offers a great overview on strengths, weaknesses, functions and strategies for terraced landscapes all over the world, summarizing in a final manifest the guidelines to provide a future for these landscapes as natural and cultural heritage.
