Kolb, Jr. V. Spitz
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Total Pages | : 20 |
Release | : 1977 |
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Author | : |
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Total Pages | : 20 |
Release | : 1977 |
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Author | : |
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Total Pages | : 20 |
Release | : 1977 |
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Author | : Ian J. S. Fairlamb |
Publisher | : Royal Society of Chemistry |
Total Pages | : 185 |
Release | : 2008 |
Genre | : Reference |
ISBN | : 0854043535 |
This Specialist Periodical Report aims to reflect the growing interest in the potential of organometallic chemistry.
Author | : Darla K. Deardorff |
Publisher | : SAGE |
Total Pages | : 560 |
Release | : 2009-08-31 |
Genre | : Language Arts & Disciplines |
ISBN | : 1412960452 |
Containing chapters by some of the world's leading experts and scholars on the subject, this book provides a broad context for intercultural competence. Including the latest research on intercultural models and theories, it presents guidance on assessing intercultural competence through the exploration of key assessment principles.
Author | : R. Po-chia Hsia |
Publisher | : John Wiley & Sons |
Total Pages | : 592 |
Release | : 2008-04-15 |
Genre | : History |
ISBN | : 1405178655 |
This volume brings together 29 new essays by leading international scholars, to provide an inclusive overview of recent work in Reformation history. Presents Catholic Renewal as a continuum of the Protestant Reformation. Examines Reformation in Eastern and Western Europe, Asia and the Americas. Takes a broad, inclusive approach – covering both traditional topics and cutting-edge areas of debate.
Author | : |
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Total Pages | : 604 |
Release | : 1895 |
Genre | : Birds |
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Author | : Retina Research Foundation (U.S.). Symposium |
Publisher | : MIT Press |
Total Pages | : 330 |
Release | : 1991 |
Genre | : Neuroreguladores |
ISBN | : 9780262121545 |
Development of the Visual System presents a selection of current studies that clearly illustrate principles of visual system development. These range from retinal development in fish and frogs to the effects of abnormal visual experience on the primary visual cortex of the cat. The book is unique in addressing four specific and fundamental aspects of development: cell lineage and cell fate, specificity and targeting of axons, specification of visual cortex, and correlates of the critical period. Encompassing technical advances in cellular and molecular biology and in video imaging and microscopy, contributions in each of these areas provide new information at the cellular and molecular levels to complement the now classic descriptions of visual development previously available at the level of neural systems.ContributorsKaren L. Allendoerfer, David M. Altshuler, Antonella Antonini, Seymour Benzer, Edward M. Callaway, Constance L. Cepko, Hollis T. Cline, Max S. Cynader, N. W. Daw, Scott E. Fraser, K. Fox, Eckhard Friauf, Anirvan Ghosh, R. W. Guillery, William A. Harris, Christine E. Holt, Lawrence C. Katz, Susan McConnell, Pamela A. Raymond, Thomas A. Reh, Carla J. Shatz, Michael P. Stryker, Claudia A. 0. Stuermer, Mriganka Sur, David L. Turner, T. N. Wiesel
Author | : |
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Total Pages | : 292 |
Release | : 1907 |
Genre | : Food |
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Author | : W. Andy Tao |
Publisher | : John Wiley & Sons |
Total Pages | : 448 |
Release | : 2019-07-10 |
Genre | : Science |
ISBN | : 1118970217 |
PROVIDES STRATEGIES AND CONCEPTS FOR UNDERSTANDING CHEMICAL PROTEOMICS, AND ANALYZING PROTEIN FUNCTIONS, MODIFICATIONS, AND INTERACTIONS—EMPHASIZING MASS SPECTROMETRY THROUGHOUT Covering mass spectrometry for chemical proteomics, this book helps readers understand analytical strategies behind protein functions, their modifications and interactions, and applications in drug discovery. It provides a basic overview and presents concepts in chemical proteomics through three angles: Strategies, Technical Advances, and Applications. Chapters cover those many technical advances and applications in drug discovery, from target identification to validation and potential treatments. The first section of Mass Spectrometry-Based Chemical Proteomics starts by reviewing basic methods and recent advances in mass spectrometry for proteomics, including shotgun proteomics, quantitative proteomics, and data analyses. The next section covers a variety of techniques and strategies coupling chemical probes to MS-based proteomics to provide functional insights into the proteome. In the last section, it focuses on using chemical strategies to study protein post-translational modifications and high-order structures. Summarizes chemical proteomics, up-to-date concepts, analysis, and target validation Covers fundamentals and strategies, including the profiling of enzyme activities and protein-drug interactions Explains technical advances in the field and describes on shotgun proteomics, quantitative proteomics, and corresponding methods of software and database usage for proteomics Includes a wide variety of applications in drug discovery, from kinase inhibitors and intracellular drug targets to the chemoproteomics analysis of natural products Addresses an important tool in small molecule drug discovery, appealing to both academia and the pharmaceutical industry Mass Spectrometry-Based Chemical Proteomics is an excellent source of information for readers in both academia and industry in a variety of fields, including pharmaceutical sciences, drug discovery, molecular biology, bioinformatics, and analytical sciences.
Author | : Naidong Weng |
Publisher | : John Wiley & Sons |
Total Pages | : 397 |
Release | : 2017-07-31 |
Genre | : Medical |
ISBN | : 1119103061 |
The first book to offer a blueprint for overcoming the challenges to successfully quantifying biomarkers in living organisms The demand among scientists and clinicians for targeted quantitation experiments has experienced explosive growth in recent years. While there are a few books dedicated to bioanalysis and biomarkers in general, until now there were none devoted exclusively to addressing critical issues surrounding this area of intense research. Target Biomarker Quantitation by LC-MS provides a detailed blueprint for quantifying biomarkers in biological systems. It uses numerous real-world cases to exemplify key concepts, all of which were carefully selected and presented so as to allow the concepts they embody to be easily expanded to future applications, including new biomarker development. Target Biomarker Quantitation by LC-MS primarily focuses on the assay establishment for biomarker quantitation—a critical issue rarely treated in depth. It offers comprehensive coverage of three core areas of biomarker assay establishment: the relationship between the measured biomarkers and their intended usage; contemporary regulatory requirements for biomarker assays (a thorough understanding of which is essential to producing a successful and defendable submission); and the technical challenges of analyzing biomarkers produced inside a living organism or cell. Covers the theory of and applications for state-of-the-art mass spectrometry and chromatography and their applications in biomarker analysis Features real-life examples illustrating the challenges involved in target biomarker quantitation and the innovative approaches which have been used to overcome those challenges Addresses potential obstacles to obtain effective biomarker level and data interpretation, such as specificity establishment and sample collection Outlines a tiered approach and fit-for-purpose assay protocol for target biomarker quantitation Highlights the current state of the biomarker regulatory environment and protocol standards Target Biomarker Quantitation by LC-MS is a valuable resource for bioanalytical scientists, drug metabolism and pharmacokinetics scientists, clinical scientists, analytical chemists, and others for whom biomarker quantitation is an important tool of the trade. It also functions as an excellent text for graduate courses in pharmaceutical, biochemistry and chemistry.