JOSEPH DUDEK V JOHN M. POPP, 373 MICH 300 (1964)
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50251
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Total Pages | : 108 |
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Total Pages | : 454 |
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Total Pages | : 74 |
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Total Pages | : 1084 |
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Total Pages | : 536 |
Release | : 1911 |
Genre | : College yearbooks |
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Author | : Vladimir Parpura |
Publisher | : Springer Science & Business Media |
Total Pages | : 701 |
Release | : 2008-12-11 |
Genre | : Medical |
ISBN | : 0387794921 |
Astrocytes were the original neuroglia that Ramón y Cajal visualized in 1913 using a gold sublimate stain. This stain targeted intermediate filaments that we now know consist mainly of glial fibrillary acidic protein, a protein used today as an astrocytic marker. Cajal described the morphological diversity of these cells with some ast- cytes surrounding neurons, while the others are intimately associated with vasculature. We start the book by discussing the heterogeneity of astrocytes using contemporary tools and by calling into question the assumption by classical neuroscience that neurons and glia are derived from distinct pools of progenitor cells. Astrocytes have long been neglected as active participants in intercellular communication and information processing in the central nervous system, in part due to their lack of electrical excitability. The follow up chapters review the “nuts and bolts” of ast- cytic physiology; astrocytes possess a diverse assortment of ion channels, neu- transmitter receptors, and transport mechanisms that enable the astrocytes to respond to many of the same signals that act on neurons. Since astrocytes can detect chemical transmitters that are released from neurons and can release their own extracellular signals there is an increasing awareness that they play physiological roles in regulating neuronal activity and synaptic transmission. In addition to these physiological roles, it is becoming increasingly recognized that astrocytes play critical roles during pathophysiological states of the nervous system; these states include gliomas, Alexander disease, and epilepsy to mention a few.
Author | : Monica Levy Andersen |
Publisher | : Springer |
Total Pages | : 514 |
Release | : 2015-11-26 |
Genre | : Medical |
ISBN | : 3319115782 |
The objective of this book is to concisely present information with respect to appropriate use of experimental rodents in research. The principles elaborated seek to provide knowledge of the techniques involved in both management and scientific research to all who use laboratory animals, with a focus on the well-being and ethics regarding rodents and also to fortify the awareness of the importance of the animal as a study object and to offer orientation and assistance in conducting laboratory research, education or tests.
Author | : K. D. Rainsford |
Publisher | : Springer |
Total Pages | : 288 |
Release | : 2015-07-30 |
Genre | : Medical |
ISBN | : 3034809271 |
In recent years there have been a number of significant developments of natural products for the treatment of rheumatic diseases, pain and gastro-intestinal ulcers and inflammation. The volume covers some of these novel developments of natural products which are of current and future interest as therapies for the above-mentioned conditions. Most available volumes cover a wide range of biological and technicological aspects of natural products and their discovery, some involving synthesis and properties of chemical compounds. The difference in this volume is that the natural products have a focus on their therapeutic effects on pain, arthritic and gastrointestinal diseases. Some of the natural products covered are either at the experimental stage of development while others are well-established clinically-used products. Each has its own unique place in therapy.
Author | : United States. Administrative Office of the United States Courts |
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Total Pages | : 288 |
Release | : 1966 |
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