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Ivermectin and Abamectin

Ivermectin and Abamectin
Author: William C. Campbell
Publisher: Springer Science & Business Media
Total Pages: 380
Release: 2012-12-06
Genre: Medical
ISBN: 1461236266

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Ivermectin and abamectin, members of the avermectin family of compounds, were introduced to the market in the 1980's as a veterinary antiparasitic drug and agricultural pesticide, respectively. Their acceptance and commercial success have been remarkable; both are highly effective and in worldwide use. The efficacy of ivermectin in river blindness has expanded the interest in its use in human medicine. In response to the intense scientific and industrial interest in ivermectin and abamectin and the likelihood that they will be forerunners of an expanding family of drugs, this comprehensive monograph satisfies the need for a review and synthesis of current knowledge about the use of these substances in crop protection as well as in cattle, sheep, swine, horses, dogs, cats, birds, fish, reptiles, and in man. This overview presents chemical, biochemical, and microbiological data, as well as pharmacological, safety, and environmental aspects and covers practical use of the compounds as antiparasitic and pesticide agents, as well as the available safety data that have emerged from the clinical experience with human applications.


Insecticides with Novel Modes of Action

Insecticides with Novel Modes of Action
Author: Isaac Ishaaya
Publisher: Springer Science & Business Media
Total Pages: 442
Release: 2013-06-29
Genre: Technology & Engineering
ISBN: 3662035650

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The future of insect control looked very bright in the 1950s and 1960s with new insecticides constantly coming onto the market. Today, however, whole classes of pesticide chemistry have fallen by the wayside due to misuse which generated resistance problems reaching crisis proportions, severe adverse effects on the environment, and public outcry that has led to increasingly stricter regulation and legislation. It is with this background, demanding the need for safer, environmentally friendly pesticides and new strategies to reduce resistance problems, that this book was written. The authors of the various chapters have a wealth of experience in pesticide chemistry, biochemical modes of action, mechanism of resistance and application, and have presented concise reviews. Each is actively involved in thedevelopment of new groups of pesticide chemistry which led to the development of novel insecticides with special impact in controlling agricultural pests. Emphasis has been given to insecticides with selective properties, such as insect growth regulators hormone mimics, ecdysone agonists), (chitin synthesis inhibitors, juvenile chloronicotinyl insecticides (imidacloprid, acetamiprid), botanical insecticides (neem, plant oils), pymetrozine, diafenthiuron, pyrrole insecticides, and others. The importance of these compounds, as components in integrated pest management programs and in insecticide resistance management strategies, is discussed. The data presented are essential in establishing new technologies and developing novel groups of compounds which will have impact on our future agricultural practices.


Approaches to Design and Synthesis of Antiparasitic Drugs

Approaches to Design and Synthesis of Antiparasitic Drugs
Author: N. Anand
Publisher: Elsevier
Total Pages: 525
Release: 1997-07-10
Genre: Medical
ISBN: 0080527523

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This book presents a comprehensive and up to date account of the chemotherapy of parasitic diseases, both human and veterinary. The book starts with an overview of parasitic diseases. The body of the book is divided into two parts: antihelminthic drugs, and antiprotozoal drugs. Both parts start with chapters highlighting the 'biochemical targets' available for chemotherapeutic interference. Individual chapters deal with one chemical class of compounds and describe their origin, structure-activity relationship, mode of action, and methods of synthesis and their status both in clinical and veterinary practice. The book will be useful to a wide spectrum of readers: students embarking on a research career in parasitic chemotherapy, clinicians (and veterinarians) and clinical pharmacologists desiring detailed information about the drugs currently in use, and pharmaceutical technologists wanting to update their knowledge of the methods of manufacture.


Clinical Veterinary Toxicology - E-Book

Clinical Veterinary Toxicology - E-Book
Author: Konnie Plumlee
Publisher: Elsevier Health Sciences
Total Pages: 504
Release: 2003-12-10
Genre: Medical
ISBN: 0323058345

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This book covers all aspects of toxicology, including toxic diseases of large animals, small animals, and exotic pets. It provides key information on how poisons affect the body, how the body responds to a foreign substance, how poisonings are diagnosed, and how poisonings are treated. Coverage includes every organ system of every species of animal with details on each body system's susceptibility to poison. Poisons affect animals differently depending on species, breed, age, gender, health status, and reproductive status. This resource addresses these differences, allowing the veterinarian to determine the class of toxicant, the mechanism of action, and the proper course of treatment. If confronted with an unknown poison, the information in this book will assist the veterinarian in formulating a list of potential poisons based on the clinical signs that the animal is exhibiting, and in choosing the appropriate tests to narrow the list to one or a few possible poisons. Most comprehensive toxicology book available Written in a user-friendly style that makes it easy to master the content Covers poisonings in both large and small domestic animals The Principles of Toxicology section provides comprehensive coverage of concepts & terminology, toxicokinetics, treatments, and regulatory information The Manifestations of Toxicoses section is devoted to differentiating between poisons based on lesions and clinical signs The Classes of Toxicants section offers detailed information on each poison, including sources, risk factors, pathophysiology, clinical signs and lesions, diagnostic testing, and treatment The author is board-certified in toxicology, and the contributors are all toxicologists and educators, ensuring authoritative, up-to-date clinical information


Canine Parasites and Parasitic Diseases

Canine Parasites and Parasitic Diseases
Author: Seppo Saari
Publisher: Academic Press
Total Pages: 287
Release: 2018-11-07
Genre: Medical
ISBN: 0128141131

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Canine Parasites and Parasitic Diseases offers a concise summary, including the distribution, epidemiology, lifecycle, morphology, clinical manifestations, diagnosis, prophylaxis and therapeutic measures on the most important parasites affecting dogs. The book includes their classification, structure, lifecycles, occurrence, and the diagnosis and treatment of infestations. Chapters are presented in a consistent and logical format with extensive use of tables, photographs and line drawings that help veterinarians and students quickly find answers to questions. The book informs on 100 different species of parasite related to the canine world and is is aimed not only at veterinary practitioners but also in dog enthusiasts, pharmacies and laboratories. Fully illustrated with high-quality figures and illustrations Provides insights on the risk factors and prevention of parasite infections in dogs and gives guidelines for anthelmintic treatment Serves professionals, students, parasitologists and veterinary scientists Present an easy-to-use handbook on the identification of canine parasites and the diseases associated with parasitic infection


Hayes' Handbook of Pesticide Toxicology

Hayes' Handbook of Pesticide Toxicology
Author:
Publisher: Academic Press
Total Pages: 2407
Release: 2010-02-15
Genre: Medical
ISBN: 0080922015

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The Handbook of Pesticide Toxicology is a comprehensive, two-volume reference guide to the properties, effects, and regulation of pesticides that provides the latest and most complete information to researchers investigating the environmental, agricultural, veterinary, and human-health impacts of pesticide use. Written by international experts from academia, government, and the private sector, the Handbook of Pesticide Toxicology is an in-depth examination of critical issues related to the need for, use of, and nature of chemicals used in modern pest management. This updated 3e carries on the book’s tradition of serving as the definitive reference on pesticide toxicology and recognizes the seminal contribution of Wayland J. Hayes, Jr., co-Editor of the first edition. Feature: Presents a comprehensive look at all aspects of pesticide toxicology in one reference work. Benefit: Saves researchers time in quickly accessing the very latest definitive details on toxicity of specific pesticides as opposed to searching through thousands of journal articles. Feature: Clear exposition of hazard identification and dose response relationships in each chapter featuring pesticide agents and actions Benefit: Connects the experimental laboratory results to real-life applications in human health, animal health and the environment. Feature: All major classes of pesticide considered. Benefit: Provides relevance to a wider variety of researchers who are conducting comparative work in pesticides or their health impacts. Feature: Different routes of exposure critically evaluated. Benefit: Connects the loop between exposure and harmful affects to those who are researching the affects of pesticides on humans or wildlife.


Synthesis of Best-Seller Drugs

Synthesis of Best-Seller Drugs
Author: Ruben Vardanyan
Publisher: Academic Press
Total Pages: 870
Release: 2016-01-07
Genre: Medical
ISBN: 0124115241

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Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation


Pesticide Chemistry and Bioscience

Pesticide Chemistry and Bioscience
Author: G. T. Brooks
Publisher: Elsevier
Total Pages: 450
Release: 1999-01-01
Genre: Technology & Engineering
ISBN: 184569841X

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This volume, with contributions from leading international experts, reports on the need to produce high quality food whilst satisfying environmental concerns. Including material on natural products, modes of action and metabolism, it covers all the key areas in pesticide chemistry and related activities. The contents outline the developments that have taken place in approaches to crop protection and our ability to develop complex, environmentally acceptable strategies for weed, pest and disease control.


Optimal Health with Multiple Sclerosis

Optimal Health with Multiple Sclerosis
Author: Allen C. Bowling, MD, PhD
Publisher: Demos Medical Publishing
Total Pages: 449
Release: 2014-10-20
Genre: Health & Fitness
ISBN: 1617052086

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The only source for reliable, evidence-based information on the relevance, safety, and effectiveness of alternative and lifestyle medicine approaches to MS treatment and the best ways to safely integrate them with conventional medicine. In addition to conventional medicine, many people with MS also use some form of alternative medicine, and there is growing evidence and interest in the effects of lifestyle factors, such as diet and exercise, on MS. Yet, until now, it has been difficult to obtain unbiased information about the MS-relevant aspects of these nonmedication approaches. Optimal Health with Multiple Sclerosis provides the accurate and unbiased information people with MS, their friends and family, health care professionals, and educators need to make responsible decisions and achieve the very best outcome. Find other options that may provide symptomatic relief when conventional therapies are limited Learn about potentially dangerous interactions between alternative therapies and medical treatments used in the management of MS Identify alternative and lifestyle therapies that are effective, low risk, and inexpensive Recognize ineffective, dangerous, or costly alternative therapies


Physical Medicine and Rehabilitation Pocketpedia

Physical Medicine and Rehabilitation Pocketpedia
Author: Matthew Shatzer, DO
Publisher: Springer Publishing Company
Total Pages: 330
Release: 2017-12-28
Genre: Medical
ISBN: 1617052930

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Pocketpedia is the essential quick reference for medical students, residents, and attending physicians in the field of physical medicine and rehabilitation. Designed for the busy clinician, this pocket-sized compendium is crammed with useful tables, charts, illustrations, and clinical tips and guidelines for effective patient care and restoration of function. Covering core topics in PM&R and field-tested in the clinic and at the bedside over two successful editions, this indispensable resource delivers the information practitioners need on a daily basis. The Third Edition has been reorganized and thoroughly updated to include the latest evidence-based treatment recommendations and protocols. Features PM&R in your pocket—perfect for rounding or concise review Distills the practical essentials with focused coverage of key topics New chapters on Ultrasound, Cancer Rehabilitation, Acupuncture, and Quality Improvement Expanded coverage of musculoskeletal rehabilitation, concussion, and interventional pain procedures Enhanced illustrations and charts Now includes downloadable ebook for anytime access on mobile devices or computer