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iPSCs from Diverse Species

iPSCs from Diverse Species
Author: Alexander Birbrair
Publisher: Academic Press
Total Pages: 274
Release: 2020-09-29
Genre: Science
ISBN: 0323851851

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The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs from Diverse Species, Volume 2 addresses how induced pluripotent stem cells (iPSCs) can be derived from different species. The volume teaches the reader about modern state-of-the-art methodologies to derive iPSCs from distinct species. This volume will cover how to derive iPSCs from species like nonhuman primates, horses, dogs, pigs, rats, rabbits, and others. It also discusses the importance of iPSCs in species conservation. Detailed description on methods used to obtain iPSCs from humans and other species expands the knowledge and understanding of stem cell biology and provides a potent tool to model diseases. The volume is written for researchers and scientists in stem cell biology, and regenerative medicine and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of iPSC technology Covers iPCSs from the following species: humans, monkeys, horses, dogs, pigs, rats, rabbits, and more Consists of contributions from stem cell leaders around the world


IPSCs in Tissue Engineering

IPSCs in Tissue Engineering
Author: Alexander Birbrair
Publisher: Elsevier
Total Pages: 430
Release: 2021-08-17
Genre: Science
ISBN: 0128238097

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The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs in Tissue Engineering, Volume 11 addresses how induced pluripotent stem cells (iPSCs) are being used to advance tissue engineering. Somatic cells can be reprogrammed into iPSCs by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This book will address the advances in research of how iPSCs are being used for the generation of different tissues and organs such as the lungs, trachea, salivary glands, skeletal muscle, liver, intestine, kidney, even the brain, and much more. This volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and tissue engineering and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine, and therapeutics Covers the engineering of the following organs: lungs, trachea, salivary glands, skeletal muscle, liver, intestine, kidney, even the brain, and more Is contributed from stem cell leaders around the world


Current Progress in IPSC-derived Cell Types

Current Progress in IPSC-derived Cell Types
Author: Alexander Birbrair
Publisher: Elsevier
Total Pages: 336
Release: 2021-06-09
Genre: Science
ISBN: 0128238844

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The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Current Progress in iPSC-derived Cell Types, Volume 10 addresses how induced pluripotent stem cells can be differentiated into different cell types. Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how research of induced pluripotent stem cells can be reprogrammed to develop new treatment technologies in regenerative medicine. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers iPSCs derived cardiomyocytes, skeletal muscles, brown adipocytes, airway epithelial cells, and much more Contributed by world-renown experts in the field


In Situ Tissue Regeneration

In Situ Tissue Regeneration
Author: Sang Jin Lee
Publisher: Academic Press
Total Pages: 458
Release: 2016-07-17
Genre: Medical
ISBN: 012802500X

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In Situ Tissue Regeneration: Host Cell Recruitment and Biomaterial Design explores the body’s ability to mobilize endogenous stem cells to the site of injury and details the latest strategies developed for inducing and supporting the body’s own regenerating capacity. From the perspective of regenerative medicine and tissue engineering, this book describes the mechanism of host cell recruitment, cell sourcing, cellular and molecular roles in cell differentiation, navigational cues and niche signals, and a tissue-specific smart biomaterial system that can be applied to a wide range of therapies. The work is divided into four sections to provide a thorough overview and helpful hints for future discoveries: endogenous cell sources; biochemical and physical cues; smart biomaterial development; and applications. Explores the body’s ability to mobilize endogenous stem cells to the site of injury Details the latest strategies developed for inducing and supporting the body’s own regenerating capacity Presents smart biomaterials in cell-based tissue engineering applications—from the cell level to applications—in the first unified volume Features chapter authors and editors who are authorities in this emerging field Prioritizes a discussion of the future direction of smart biomaterials for in situ tissue regeneration, which will affect an emerging and lucrative industry


Human Embryonic Stem Cells

Human Embryonic Stem Cells
Author: Arlene Chiu
Publisher: Springer Science & Business Media
Total Pages: 455
Release: 2003-08-01
Genre: Science
ISBN: 1592594239

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A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.


Human Stem Cell Manual

Human Stem Cell Manual
Author: Suzanne Peterson
Publisher: Academic Press
Total Pages: 652
Release: 2012-10-22
Genre: Science
ISBN: 0123854741

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This manual is a comprehensive compilation of "methods that work" for deriving, characterizing, and differentiating hPSCs, written by the researchers who developed and tested the methods and use them every day in their laboratories. The manual is much more than a collection of recipes; it is intended to spark the interest of scientists in areas of stem cell biology that they may not have considered to be important to their work. The second edition of the Human Stem Cell Manual is an extraordinary laboratory guide for both experienced stem cell researchers and those just beginning to use stem cells in their work. Offers a comprehensive guide for medical and biology researchers who want to use stem cells for basic research, disease modeling, drug development, and cell therapy applications Provides a cohesive global view of the current state of stem cell research, with chapters written by pioneering stem cell researchers in Asia, Europe, and North America Includes new chapters devoted to recently developed methods, such as iPSC technology, written by the scientists who made these breakthroughs


Stem Cells in Reproductive Medicine

Stem Cells in Reproductive Medicine
Author: Carlos Simón
Publisher: Cambridge University Press
Total Pages: 199
Release: 2013-07-04
Genre: Medical
ISBN: 1107034477

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Stem cell science has the potential to impact human reproductive medicine significantly - cutting edge technologies allow the production and regeneration of viable gametes from human stem cells offering potential to preciously infertile patients. Written by leading experts in the field Stem Cells in Reproductive Medicine brings together chapters on the genetics and epigenetics of both the male and female gametes as well as advice on the production and regeneration of gene cells in men and women, trophoblasts and endometrium from human embryonic and adult stem cells. Although focussing mainly on the practical elements of the use of stem cells in reproductive medicine, the book also contains a section on new developments in stem cell research. The book is essential reading for reproductive medicine clinicians, gynecologists and embryologists who want to keep abreast of practical developments in this rapidly developing field.


Kidney Transplantation, Bioengineering, and Regeneration

Kidney Transplantation, Bioengineering, and Regeneration
Author: Giuseppe Orlando
Publisher: Academic Press
Total Pages: 1252
Release: 2017-06-08
Genre: Science
ISBN: 0128018364

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Kidney Transplantation, Bioengineering, and Regeneration: Kidney Transplantation in the Regenerative Medicine Era investigates how the field of regenerative medicine is changing the traditional premises of solid organ transplantation, specifically within the field of kidney transplantation. In Section 1, chapters illustrate the state of the art in kidney transplantation as well as the research behind the bioengineering and regeneration of kidney organoids for therapeutic renal replacement. In Section II, chapters catalog the technologies that are being developed and the methods that are being implemented to bioengineer or regenerate kidneys in order to restore function, while critically highlighting those technological advances which hold the most promise. The book thus encompasses clinical renal transplantation, tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, as they are all applied to the kidney. Focuses on the synergy between renal organ transplantation and regenerative medicine, highlighting the advances within transplantation, bioengineering, regeneration, and repair Educates the transplant community on important regenerative medicine research pertinent to kidney transplantation Develops a shared language for clinicians, surgeons, and basic researchers to reach across the fields of transplantation and regenerative medicine, and facilitate more productive investigation and research Catalogs the technologies being developed and methods being implemented to bioengineer or regenerate kidneys to restore function


Conservation Genetics in the Age of Genomics

Conservation Genetics in the Age of Genomics
Author: George Amato
Publisher: Columbia University Press
Total Pages: 504
Release: 2009-08-07
Genre: Science
ISBN: 0231502311

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Genome sequencing enables scientists to study genes over time and to test the genetic variability of any form of life, from bacteria to mammals. Thanks to advances in molecular genetics, scientists can now determine an animal's degree of inbreeding or compare genetic variation of a captive species to wild or natural populations. Mapping an organism's genetic makeup recasts such terms as biodiversity and species and enables the conservation of rare or threatened species, populations, and genes. By introducing a new paradigm for studying and preserving life at a variety of levels, genomics offers solutions to previously intractable problems in understanding the biology of complex organisms and creates new tools for preserving the patterns and processes of life on this planet. Featuring a number of high-profile researchers, this volume introduces the use of molecular genetics in conservation biology and provides a historical perspective on the opportunities and challenges presented by new technologies. It discusses zoo-, museum-, and herbarium-based biological collections, which have expanded over the past decade, and covers the promises and problems of genomic and reproductive technology. The collection concludes with the philosophical and legal issues of conservation genetics and their potential effects on public policy.


Novel Concepts in iPSC Disease Modeling

Novel Concepts in iPSC Disease Modeling
Author: Alexander Birbrair
Publisher: Academic Press
Total Pages: 338
Release: 2022-01-08
Genre: Science
ISBN: 0128238836

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The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs - Novel Concepts, Volume 15 addresses how important induced pluripotent stems cells are and how can they can help treat certain diseases. Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how induced pluripotent stem cells are being used for treatment of different disorders, such as liver disease, type-1 diabetes, Parkinson’s disease, macular degeneration of the retina and much more. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers spinal cord injuries, type-1 diabetes, liver disease, Parkinson’s disease, graft vs. host disease, and much more Contributed by world-renown experts in the field