Ionic Channels Of Excitable Membranes PDF Download
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Author | : Bertil Hille |
Publisher | : Sinauer Associates, Incorporated |
Total Pages | : 638 |
Release | : 1992 |
Genre | : Medical |
ISBN | : |
Download Ionic Channels of Excitable Membranes Book in PDF, ePub and Kindle
This new, fully revised and expanded edition of Ionic Channels of Excitable Membranes includes new chapters on fast chemical synapses, modulation through G protein coupled receptors and second messenger systems, molecules cloning, site directed mutagenesis, and cell biology. It begins with the classical biophysical work of Hodgkin and Huxley and then weaves a description of the known ionic channels together with their biological functions. The book continues by developing the physical and molecular principles needed for explaining permeation, gating, pharmacological modification, and molecular diversity, and ends with a discussion of channel evolution. Ionic Channels of Excitable Membranes is written to be accessible and interesting to biological and physical scientists of all kinds.
Author | : Jie Zheng |
Publisher | : CRC Press |
Total Pages | : 682 |
Release | : 2015-02-25 |
Genre | : Medical |
ISBN | : 1466551429 |
Download Handbook of Ion Channels Book in PDF, ePub and Kindle
The New Benchmark for Understanding the Latest Developments of Ion ChannelsIon channels control the electrical properties of neurons and cardiac cells, mediate the detection and response to sensory stimuli, and regulate the response to physical stimuli. They can often interact with the cellular environment due to their location at the surface of ce
Author | : Bruce Alberts |
Publisher | : |
Total Pages | : 0 |
Release | : 2002 |
Genre | : Cytology |
ISBN | : 9780815332183 |
Download Molecular Biology of The Cell Book in PDF, ePub and Kindle
Author | : János Salánki |
Publisher | : |
Total Pages | : 0 |
Release | : 1981 |
Genre | : |
ISBN | : 9789630526913 |
Download Physiology of Excitable Membranes Book in PDF, ePub and Kindle
Author | : David J. Aidley |
Publisher | : Cambridge University Press |
Total Pages | : 324 |
Release | : 1996-08-13 |
Genre | : Medical |
ISBN | : 9780521498821 |
Download Ion Channels Book in PDF, ePub and Kindle
Ion channels are crucial components of living cells. Situated in the cell's membranes. they allow particular ions to pass from one side of the membrane to the other. In recent years the patch clamp technique has allowed the activity of individual channels to be measured, and recombinant DNA technology has led to fascinating detail on their structure. Together, these technical advances have produced a great flowering of knowledge and understanding about the subject, itself leading to further breakthroughs in science and medicine. Ion Channels provides an introduction to this scientific endeavour. It emphasises the molecular structure of channels as determined by gene cloning technology. This knowledge illuminates discussions of the permeability and selectivity of channels, their gating and modulation, their responses to drugs and toxins and the human diseases caused when they do not function properly.
Author | : Frances M. Ashcroft |
Publisher | : Academic Press |
Total Pages | : 505 |
Release | : 1999-10-20 |
Genre | : Science |
ISBN | : 0080535216 |
Download Ion Channels and Disease Book in PDF, ePub and Kindle
Ion channels are membrane proteins that act as gated pathways for the movement of ions across cell membranes. They play essential roles in the physiology of all cells. In recent years, an ever-increasing number of human and animal diseases have been found to result from defects in ion channel function. Most of these diseases arise from mutations in the genes encoding ion channel proteins, and they are now referred to as the channelopathies. Ion Channels and Disease provides an informative and up-to-date account of our present understanding of ion channels and the molecular basis of ion channel diseases. It includes a basic introduction to the relevant aspects of molecular biology and biophysics and a brief description of the principal methods used to study channelopathies. For each channel, the relationship between its molecular structure and its functional properties is discussed and ways in which genetic mutations produce the disease phenotype are considered. This book is intended for research workers and clinicians, as well as graduates and advanced undergraduates. The text is clear and lively and assumes little knowledge, yet it takes the reader to frontiers of what is currently known about this most exciting and medically important area of physiology. Introduces the relevant aspects of molecular biology and biophysics Describes the principal methods used to study channelopathies Considers single classes of ion channels with summaries of the physiological role, subunit composition, molecular structure and chromosomal location, plus the relationship between channel structure and function Looks at those diseases associated with defective channel structures and regulation, including mutations affecting channel function and to what extent this change in channel function can account for the clinical phenotype
Author | : Piergiorgio Strata |
Publisher | : Springer Science & Business Media |
Total Pages | : 153 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 3642756360 |
Download Mg2+ and Excitable Membranes Book in PDF, ePub and Kindle
This volume presents the most recent research findings on the key role played by Mg2+ in the regulation of ion channels in excitable tissue. Contributions describe the multiple actions exerted by Mg2+ on the different types on ion channels controlling nerve and cardiac cell activity. Recent developments in the detection of single ion channel activity provide important insights into the mechanisms of action of Mg2+ at the channel level.
Author | : Werner Schiebler |
Publisher | : |
Total Pages | : 22 |
Release | : 1977 |
Genre | : |
ISBN | : |
Download Biochemical investigations of ionic channels in excitable membranes Book in PDF, ePub and Kindle
Author | : Wolfgang B. Liedtke, MD, PH.D. |
Publisher | : CRC Press |
Total Pages | : 502 |
Release | : 2006-09-29 |
Genre | : Medical |
ISBN | : 1420005847 |
Download TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades Book in PDF, ePub and Kindle
Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st
Author | : Wulfram Gerstner |
Publisher | : Cambridge University Press |
Total Pages | : 591 |
Release | : 2014-07-24 |
Genre | : Computers |
ISBN | : 1107060834 |
Download Neuronal Dynamics Book in PDF, ePub and Kindle
This solid introduction uses the principles of physics and the tools of mathematics to approach fundamental questions of neuroscience.