Ion Channels As Therapeutic Targets PDF Download
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Author | : |
Publisher | : Academic Press |
Total Pages | : 468 |
Release | : 2016-03-31 |
Genre | : Science |
ISBN | : 0128052422 |
Download Ion Channels as Therapeutic Targets, Part B Book in PDF, ePub and Kindle
This volume is the second part of the thematic on Ion Channels as Therapeutic Targets. The popular Advances in Protein Chemistry and Structural Biology series, an essential resource for protein chemists, brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics. Provides cutting-edge developments in protein chemistry and structural biology Discusses the use of ion channels as therapeutic targets Chapters are written by authorities in their field Targeted to a wide audience of researchers, specialists, and students
Author | : Gary Stephens |
Publisher | : Springer Nature |
Total Pages | : 540 |
Release | : |
Genre | : |
ISBN | : 3031521978 |
Download Ion Channels as Targets in Drug Discovery Book in PDF, ePub and Kindle
Author | : |
Publisher | : Academic Press |
Total Pages | : 404 |
Release | : 2016-02-23 |
Genre | : Science |
ISBN | : 0128052104 |
Download Ion Channels as Therapeutic Targets, Part A Book in PDF, ePub and Kindle
Ion Channels as Therapeutic Targets is the latest volume in the popular Advances in Protein Chemistry and Structural Biology series, an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics. Provides cutting-edge developments in protein chemistry and structural biology Discusses the use of ion channels as therapeutic targets Chapters are written by authorities in their field Targeted to a wide audience of researchers, specialists, and students
Author | : Arpad Szallasi |
Publisher | : Academic Press |
Total Pages | : 530 |
Release | : 2015-04-09 |
Genre | : Medical |
ISBN | : 0124200796 |
Download TRP Channels as Therapeutic Targets Book in PDF, ePub and Kindle
TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use is authored by experts across academia and industry, providing readers with a complete picture of the therapeutic potential and challenges associated with using TRP channels as drug targets. This book offers a unique clinical approach by covering compounds that target TRP channels in pre-clinical and clinical phases, also offering a discussion of TRP channels as biomarkers. An entire section is devoted to the novel and innovative uses of these channels across a variety of diseases, offering strategies that can be used to overcome the adverse effects of first generation TRPV1 antagonists. Intended for all researchers and clinicians working toward the development of successful drugs targeting TRP channels, this book is an essential resource chocked full of the latest clinical data and findings. Contains comprehensive coverage of TRP channels as therapeutic targets, from emerging clinical indications to completed clinical trials Discusses TRP channels as validated targets, ranging from obesity and diabetes through cancer and respiratory disorders, kidney diseases, hypertension, neurodegenerative disorders, and more Provides critical analysis of the complications and side effects that have surfaced during clinical trials, offering evidence-based suggestions for overcoming them
Author | : Rossen Donev |
Publisher | : |
Total Pages | : |
Release | : 2016 |
Genre | : Ion channels |
ISBN | : |
Download Ion Channels as Therapeutic Targets Book in PDF, ePub and Kindle
Author | : Brian Cox |
Publisher | : Royal Society of Chemistry |
Total Pages | : 384 |
Release | : 2014-09-24 |
Genre | : Medical |
ISBN | : 1849731861 |
Download Ion Channel Drug Discovery Book in PDF, ePub and Kindle
A rapidly growing field, this book covers the recent advances in screening technology, ion channel structure and modelling, with up-to-date case histories.
Author | : John T. Farrar |
Publisher | : |
Total Pages | : 54 |
Release | : 2006 |
Genre | : |
ISBN | : |
Download Ion Channels as Therapeutic Targets in Neuropathic Pain Book in PDF, ePub and Kindle
Author | : |
Publisher | : Academic Press |
Total Pages | : 338 |
Release | : 2017-05-18 |
Genre | : Medical |
ISBN | : 0128104147 |
Download Ion Channels Down Under Book in PDF, ePub and Kindle
Ion Channels Down Under, Volume 79 provides up-to-date information on ion channel pharmacology, their pharmacological modulators, and their role in a diverse range of poorly treated medical conditions. This new volume covers specific topics relating to Receptors and the Diversity in their Structure and Pharmacology, Acid-Sensing Ion Channel Pharmacology, Past, Present and Future, Sodium Channels and Venom Peptide Pharmacology, the Role of Non-Neuronal TRPV4 Signaling in Inflammatory Processes, and Genetically Encoded Calcium Indicators as Probes to Assess the Role of Calcium Channels in Disease and for High-Throughput Drug Discovery. Contributors in this series include prominent scientists and highly-recognized experts with major accomplishments in the field of ion channel pharmacology. Topics covered include the role of ion channels in health and disease, ion channels as therapeutic targets and the molecular pharmacology of ion channels. Provides a must read book on ion channel pharmacology Contains up-to-date information on a number of ion channels, their pharmacological modulators, and their role in a diverse range of poorly treated medical conditions Contains contributions from prominent scientists and highly-recognized experts with major accomplishments in the field
Author | : Steven Howard |
Publisher | : Royal Society of Chemistry |
Total Pages | : 314 |
Release | : 2015-06-17 |
Genre | : Medical |
ISBN | : 1782625658 |
Download Fragment-Based Drug Discovery Book in PDF, ePub and Kindle
Fragment-based drug discovery is a rapidly evolving area of research, which has recently seen new applications in areas such as epigenetics, GPCRs and the identification of novel allosteric binding pockets. The first fragment-derived drug was recently approved for the treatment of melanoma. It is hoped that this approval is just the beginning of the many drugs yet to be discovered using this fascinating technique. This book is written from a Chemist's perspective and comprehensively assesses the impact of fragment-based drug discovery on a wide variety of areas of medicinal chemistry. It will prove to be an invaluable resource for medicinal chemists working in academia and industry, as well as anyone interested in novel drug discovery techniques.
Author | : David J. Triggle |
Publisher | : John Wiley & Sons |
Total Pages | : 492 |
Release | : 2006-08-21 |
Genre | : Science |
ISBN | : 3527607749 |
Download Voltage-Gated Ion Channels as Drug Targets Book in PDF, ePub and Kindle
Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology. After an introduction to the topic, the authors evaluate the structure and function of ion channels, as well as related drug interaction. A section on assay technologies is followed by a section each on calcium, sodium and potassium channels. Further chapters cover genetic and acquired channelopathies, before the book closes with a look at safety issues in ion channel drug development. For medicinal and pharmaceutical chemists, biochemists, molecular biologists and those working in the pharmaceutical industry.