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Invertebrate Cytokines and the Phylogeny of Immunity

Invertebrate Cytokines and the Phylogeny of Immunity
Author: Alain Beschin
Publisher: Springer Science & Business Media
Total Pages: 192
Release: 2012-12-06
Genre: Science
ISBN: 364218670X

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Based on the assumption that invertebrates as well as vertebrates possess factors regulating hematopoiesis, response to infection or wounding, studies dealing with the evolution of immunity have focused on the isolation and characterization of putative cytokine-related molecules from invertebrates. Until recently, most of our knowledge of cytokine- and cytokine receptor-like molecules in invertebrates has relied on functional assays and similarities at the physicochemical level. As such, a phylogenetic relationship between invertebrate cytokine-like molecules and invertebrate counterparts could not be convincingly demonstrated. In the present book, recent studies demonstrating cytokine-like activities and related signaling pathways in invertebrates are critically reviewed, focusing on findings from molecular biology and taking advantage of the completion of the genome from the fly Drosophila and the worm Caenorhabditis elegans.


Phylogenetic Perspectives on the Vertebrate Immune System

Phylogenetic Perspectives on the Vertebrate Immune System
Author: Gregory Becker
Publisher: Springer Science & Business Media
Total Pages: 380
Release: 2012-12-06
Genre: Science
ISBN: 1461512913

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This book contains the proceedings of the first meeting on invertebrate immunity ever sponsored as a summer research conference by the Federation of American Societies for Experimental Biology (FASEB). The conference was held in Copper Mountain, CO from July 11-16, 1999. It was a an extension of a New York Academy of Sciences meeting entitled "Primordial Immunity: Foundations for the Vertebrate Immune System" held on May 2-5,1993 at the Marine Biological Laboratories in Woods Hole, MA. The proceedings of that meeting were published in The Annals of the New York Academy of Sciences (volume 712). At that meeting all the attendes agreed that this type of conference (a relatively small focused gathering) allowed for participation by investigators at all levels of their careers. We further agreed that we should search for a forum that would allow this meeting to continue. The FASEB Summer Research Conference was an excellent vehicle for this type of meeting. Furthermore, this year's participants decided to continue this meeting as a regularly scheduled FASEB sponsored event. This was a unique conference in the sense that it focused upon mechanisms of development and defense in protostome and deuterostome invertebrates and lower vertebrates. There was a strong emphasis on evolutionary cell biology, phylogenetic inferences and the evolution of recognition and regulatory systems.


Immunology of Annelids

Immunology of Annelids
Author: Martin Bilej
Publisher: CRC Press
Total Pages: 316
Release: 1993-12-16
Genre: Medical
ISBN: 9780849349096

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Immunology of Annelids provides a state-of-the-art review of the biological and biochemical processes involved in defense reactions of annelids. The book covers phylogeny, taxonomy, and fundamental body structure to provide basic information essential to developing a full understanding of the defense system of an organism. Physiological aspects of the relationship between the immune systems and cells and their limitations are discussed in detail, and the role of cells in cellular defense, transplantation, and humoral defenses is explained. The importance of annelids and their defense reaction from the phylogenetic standpoint is examined in a chapter comparing vertebrate and invertebrate defense strategies. Immunology of Annelids is a practical reference for cell biologists, immunologists, evolutionary and developmental biologists, and other researchers who need insight into the development and hierarchy of immune reactions.


Evolution of Immune Reactions

Evolution of Immune Reactions
Author: Petr Sima
Publisher: CRC Press
Total Pages: 272
Release: 1990-08-27
Genre: Medical
ISBN: 9780849365935

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This book on phylogeny and immunity reconstructs the history and evolutionary pathways of immunity among the various forms of life. The authors argue that the immunity could have evolved different adequately successful patterns in the animal sub-regnum which are strictly determined by the morpho-physiological possibilities of the animals. They state that the vertebrate type of immunity evolved only in the chordate branch. The publication devotes special attention to the arthropods and molluscs, as they have attracted more investigative efforts than any other invertebrate taxa. The authors selected Agnatha, Chondrichthyes, and Osteichthyes from the vertebrate taxa in order to show where and how the morphofunctional basis of the truly adapative immunity of the endothermic tetrapods gradually evolved. Each chapter gives the description of the origin and interrelationships of the representatives of the taxon in question. Also given are the main biological, morphological, non-morphological and immune attributes. Emphasized throughout the book is the central idea that immunological reactions are a part of the overall biological phenomena and should be studied only from this aspect. The authors express that the fields of comparative and evolutionary immunology will provide inspiration for further investigations in biomedicine in the near future.


Immunity in Evolution

Immunity in Evolution
Author: John J. Marchalonis
Publisher:
Total Pages: 344
Release: 1977
Genre: Science
ISBN:

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Origin and Evolution of the Vertebrate Immune System

Origin and Evolution of the Vertebrate Immune System
Author: L. Du Pasquier
Publisher: Springer
Total Pages: 326
Release: 2014-03-12
Genre: Medical
ISBN: 9783642596759

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The comparative approach to immunology can be traced to the era of Pasteur and Metchnikov in which observations regarding foreign recognition in invertebrates was a factor in the develop ment of the principal concepts that created the foundation of what now is the broad field of immunology. With each major experimental and conceptual breakthrough, the classical, albeit essential, question has been asked "are the immune systems of phylogenetically primitive vertebrates and invertebrates similar to that of mammals?" Somewhat surprisingly for the jawed verte brates, the general answer has been a qualified form of "yes", whereas for agnathans and invertebrate phyla it has been "no" so far. The apparent abruptness in the appearance of the immune system of vertebrates is linked to the introduction of the somatic generation of the diversity of its antigen specific receptors. Therefore the questions regarding the origin and evolution of the specific immune system revolve around this phenomenon. With respect to the origin of the system (aside from the or igin of the rearranging machinery itself, the study of which is still in its infancy) one can ask questions about the cellular and mo lecular contexts in which the mechanism was introduced.


New Advances and Contributions to Fish Biology

New Advances and Contributions to Fish Biology
Author: Hakan Turker
Publisher: BoD – Books on Demand
Total Pages: 310
Release: 2012-11-21
Genre: Science
ISBN: 953510909X

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This book provides an understanding on a large variety of related topics in fish biology. The further development on molecular and cellular biology and ecology leads to assimilate the newer scientific knowledge in this area. Leading research works from around the world are brought together in this book to produce a valuable source of reference for teachers, researcher, and advanced students of biological science. The fist three chapters of this book give a general description of the complex biology of the immune response. Detailed descriptions were also included on understanding of cytokine regulation in teleost immune system. The second three chapters provide information on the environmental stressors on the responses of freshwater fish across molecular to population level. Then, the following two chapters review two special topics; the roles of the atrium and the ventricle across teleost species and the tracer methodologies on the measurements of carbohydrate metabolism. The last chapter discusses the variables that are involved in the feeding behavior of a predatory freshwater fish species.


The Evolution of the Immune System

The Evolution of the Immune System
Author: Davide Malagoli
Publisher: Academic Press
Total Pages: 384
Release: 2016-07-21
Genre: Medical
ISBN: 012802013X

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The Evolution of the Immune System: Conservation and Diversification is the first book of its kind that prompts a new perspective when describing and considering the evolution of the immune system. Its unique approach summarizes, updates, and provides new insights on the different immune receptors, soluble factors, and immune cell effectors. Helps the reader gain a modern idea of the evolution of the immune systems in pluricellular organisms Provides a complete overview of the most studied and hot topics in comparative and evolutionary immunology Reflects the organisation of the immune system (cell-based, humoral [innate], humoral [adaptive]) without introducing further and misleading levels of organization Brings concepts and ideas on the evolution of the immune system to a wide readership


Invertebrate Immune Responses

Invertebrate Immune Responses
Author: E.L. Cooper
Publisher: Springer Science & Business Media
Total Pages: 254
Release: 2013-06-29
Genre: Medical
ISBN: 3642798470

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E. L. Cooper In Volume 23 we considered, in seven chapters, the basic armamentarium of the invertebrate immune system and its cells, as well as an analysis of antigens, setting the stage for the initiation of an immune response. We studied cell products, natural or induced, as revealed by nonspecific and specific responses following antigenic challenge such as the pro phenol oxidase system, the lytic responses, the Ig superfamily, and the place this family offers invertebrates and insect hemolymph proteins as candidates for membership. At this point, these various topics seemed to converge, almost to overlap, in some instances, presenting a challenge as to how to move from one subject to another. Chapter 1, in this volume offers the bridge to Volume 23 and its final Chapter 7. This Volume 24 contains contributions pertaining to cell activities and the environment. Chapters 1-4 refer specifically to interactions between cells and the integration of cell activities. The focus is on a functional immune system, with antigenic challenge as a subtopic. In Chapters 5-7, the environment is considered from several points of view and the main subtopic here is the result of the consequences of connections and missed signals. The internal and external environments are treated, revealing what may happen when normal immune responses are interfered with. All this is integrated by the consideration of the three great regulatory systems, the ever-present network that somehow acts as the monitor or control for all incoming and outgoing signals.


Insect Immunology

Insect Immunology
Author: Nancy E. Beckage
Publisher: Academic Press
Total Pages: 360
Release: 2011-04-28
Genre: Science
ISBN: 9780080556338

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This work is the first book-length publication on the topic of insect immunology since 1991, complementing earlier works by offering a fresh perspective on current research. Interactions of host immune systems with both parasites and pathogens are presented in detail, as well as the genomics and proteomics, approaches which have been lacking in other publications. Beckage provides comprehensive coverage of topics important to medical researchers, including Drosophila as a model for studying cellular and humoral immune mechanisms, biochemical mediators of immunity, and insect blood cells and their functions. Encompasses the most important topics of insect immunology including mechanisms, genes, proteins, evolution and phylogeny Provides comprehensive coverage of topics important to medical researchers including Drosophila as a model for studying cellular and humoral immune mechanisms, biochemical mediators of immunity, and insect blood cells and their functions Most up-to-date information published with contributions from international leaders in the field