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Interpretation and Medical Application of Laser Biospeckle

Interpretation and Medical Application of Laser Biospeckle
Author: Oliver Bendix Thompson
Publisher:
Total Pages: 152
Release: 2014
Genre: Blood flow
ISBN:
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Laser biospeckle is the dynamic laser speckle pattern produced by illuminating tissue with laser light. The dynamic nature of the speckle indicates the movement of particles in the tissue, particularly blood cells. Contrast analysis of laser biospeckle generates flow maps showing areas of higher or lower blood flow, for example vessels or background perfusion, and can detect changes in flow associated with inflammation, wounds or disease. This thesis presents methods of analysing laser speckle contrast, particularly a method using multiple camera exposures to generate the find the same spectral information from laser speckle fluctuations as laser Doppler, allowing quantitative measurements of flow. This work also presents a correction for spatial averaging in speckle, and confirms the validity of that correction using simulation and experiment. Spatial effects on laser speckle imaging techniques in tissues are tested experimentally. Multiple exposure speckle imaging was tested in vivo in a variety of situations, and clinically in measurements around diabetic foot ulcers. Measurements were made on three groups: patients with diabetic foot ulcers, patients with peripheral vascular disease, and normal control subjects. No difference in mean flow speed was found between the groups, but a significant difference in mean static contrast, indicating blood volume in tissue, was found.

Medical Applications of Lasers

Medical Applications of Lasers
Author: D.R. Vij
Publisher: Springer Science & Business Media
Total Pages: 381
Release: 2013-11-27
Genre: Technology & Engineering
ISBN: 1461509297
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A careful review of the literature covering various aspects of applications of lasers in science and technology reveals that lasers are being applied very widely throughout the entire gamut of physical medicine. After surveying the current developments taking place in the field of medical applications of lasers, it was considered appropriate to bring together these efforts of international research scientists and experts into one volume. It is with this aim that the editors have prepared this volume which brings current research and recent developments to the attention of a wide spectrum of readership associated with hospitals, medical institutions and universities world wide, including also the medical instrument industry. Both teachers and students in the medical faculties will especially find this compendium quite useful. This book is comprised of eleven chapters. All of the important medical applications of lasers are featured. The editors have made every effort that individual chapters are self-contained and written by experts. Emphasis has been placed on straight and simple presentation of the subject matter so that even the new entrants into the field will find the book of value.

Laser Applications in Medicine and Biology

Laser Applications in Medicine and Biology
Author: M.L. Wolbarsht
Publisher: Springer Science & Business Media
Total Pages: 307
Release: 2013-06-29
Genre: Science
ISBN: 1461307457
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The diversity of the chapters presented in this volume illustrates not only the many applications of lasers, but also the fact that, in many cases, these are not new uses of lasers, but rather improvements of laser techniques already widely accepted in both research and clinical situations. Biological reactions to some special aspects of laser exposure continue to show new effects, which have implications for the ever-present topic of laser safety. Such biological reactions are included in fields of research which depend on properties of electromagnetic radiation exposure only possible with lasers, for example, the short pulses necessary for the temperature-jump experiments reviewed by Reiss: Speciality lasers, such as the transverse excitation atmospheric (TEA) or excimer lasers, add new wavelengths and pulse domains to those already available for biological application. A description of these new types of lasers by Osgood is included to indicate new possibilities for future use and to avoid limiting our coverage to well-developed present-day applications. Hillenkamp and Kaufmann describe a microprobe mass spectrograph for analysis of the minute amounts of material evaporated by a laser pulse. The analytical possibilities of this instrument are far-reaching, and some of the various results are described to illustrate the power of their method, as well as to show the types of problems that are suitable for it. The initial steps in photosynthesis have become the subject of intensive investigation.

Laser Applications in Medicine and Biology

Laser Applications in Medicine and Biology
Author: Myron Wolbarsht
Publisher: Springer Science & Business Media
Total Pages: 358
Release: 2012-12-06
Genre: Technology & Engineering
ISBN: 1461573262
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Much of the material in this book represents a departure from that presented earlier in the series. Volumes 1 and 2 presented almost exclusively reviews by American authors of American work. As science is international, it is rare that in two different parts of the world large groups of researchers in the same field remain relatively uninformed about each other's work. However, during the time since the initiation of this series, a large body of research has grown up in Russia that is almost unknown outside, as the original reports are largely untranslated. For this reason, an extensive review is presented here of the entire field of Russian applications of lasers in medicine and biology. Although the author, Dr. Gamaleya, has not worked directly with many of the applications, he has a general background in laser usage and has received much help from his colleagues in assembling the material. His review is restricted to Russian research. This does not mean that he is unaware of Western advances, rather that he has restricted his material to the parts that are peculiarly Russian or are significant confir mations of earlier work. Some of the Russian developments are quite novel and will certainly suggest to the careful reader new interpretations of old data, and possibly even new lines of research. The mechanisms proposed for the interaction of the high-intensity monochromatic light from lasers with biological material continue to grow in complexity.

Laser Applications in Medicine and Biology

Laser Applications in Medicine and Biology
Author: Myron Wolbarsht
Publisher: Springer Science & Business Media
Total Pages: 420
Release: 2013-06-29
Genre: Technology & Engineering
ISBN: 1461573238
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In the intervening years since the publication of Volume I, the develop ment of new uses for the various types of lasers has proceeded at a rate more rapid than even the most fanciful dreamers envisioned. Of course, the main effort has been on the laser itself-new wavelengths, shorter and longer time domains for pulses, increases in power, and, most important, greater reliability. In its first stage the laser was described as a solution in search of a problem. The production of holograms was one problem whose solution seemed to involve large number of lasers. However that proposal had its own difficulties, for the hologram itself was described as a solution searching for a problem. But all of that now is a chapter from ancient history . On the current scene the laser is used in industrial pro duction lines, as a classroom item at all levels of education, and in com mercial usage such that the public is generally exposed to the laser devices themselves. Trial runs have been made, e. g. , of laser-based supermarket checkout devices and as commercial exploitation of this item begins, cer tainly many more similar adaptations will follow. However, the shift in emphasis from research usage of lasers to de velopment and production has been relative rather than absolute. The use of the laser in research has not lessened; rather it has grown at as fast a pace. Yet a similar trend is seen there also.

Lasers in Medicine

Lasers in Medicine
Author: Ronald W. Waynant
Publisher: CRC Press
Total Pages: 354
Release: 2011-12-20
Genre: Medical
ISBN: 142004074X
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The use of lasers in medical practice has dramatically increased over the years. Lasers and modern optics have largely been unexplored in medical science. This contributed work is both optimistic and cautionary in its expert evaluation of the state-of-the-art medical use of laser technology. The use of lasers to improve upon conventional practice i

Lasers for Medical Applications

Lasers for Medical Applications
Author: Helena Jelínková
Publisher: Elsevier
Total Pages: 827
Release: 2013-09-30
Genre: Technology & Engineering
ISBN: 0857097547
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Lasers have a wide and growing range of applications in medicine. Lasers for Medical Applications summarises the wealth of recent research on the principles, technologies and application of lasers in diagnostics, therapy and surgery. Part one gives an overview of the use of lasers in medicine, key principles of lasers and radiation interactions with tissue. To understand the wide diversity and therefore the large possible choice of these devices for a specific diagnosis or treatment, the respective types of the laser (solid state, gas, dye, and semiconductor) are reviewed in part two. Part three describes diagnostic laser methods, for example optical coherence tomography, spectroscopy, optical biopsy, and time-resolved fluorescence polarization spectroscopy. Those methods help doctors to refine the scope of involvement of the particular body part or, for example, to specify the extent of a tumor. Part four concentrates on the therapeutic applications of laser radiation in particular branches of medicine, including ophthalmology, dermatology, cardiology, urology, gynecology, otorhinolaryngology (ORL), neurology, dentistry, orthopaedic surgery and cancer therapy, as well as laser coatings of implants. The final chapter includes the safety precautions with which the staff working with laser instruments must be familiar. With its distinguished editor and international team of contributors, this important book summarizes international achievements in the field of laser applications in medicine in the past 50 years. It provides a valuable contribution to laser medicine by outstanding experts in medicine and engineering. Describes the interaction of laser light with tissue Reviews every type of laser used in medicine: solid state, gas, dye and semiconductor Describes the use of lasers for diagnostics

Laser Applications in Medicine and Biology

Laser Applications in Medicine and Biology
Author: Myron Wolbarsht
Publisher: Springer Science & Business Media
Total Pages: 299
Release: 2012-12-06
Genre: Technology & Engineering
ISBN: 1461573203
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If a basic advance in physics has any practical applications, among the first are those in biology and medicine. This is quite striking when one considers even such unlikely things as the Mössbauer effect and X rays. Within a very short period of their discovery, they had welI-formulated biological and medical applications. The discovery of the laser is no exception. AIthough the theoretical basis for it was established in 1917 by Einstein, the techniques and materials necessary for building a laser were not then available. The laser has revitalized everything connected with optics. It has furnished the experimenter and the teacher with a pseudo-point source. It has translated many a theoretical experiment into one that can be realized practicalIy. The highly monochromatic and coherent aspects of the light, in addition to the high power levels that can be attained, add greatly to the usefulness in this regard. The industrial applictions range from punching holes in baby bottle nipples to a surveyor's instrument of such accuracy that it can plot tlie position of the moon relative to the earth within a few feet. Many years of very informal meeting on the subject of lasers in medicine and biology have been sponsored by the Gordon Research Conferences. The present book is an outgrowth of the discussions that took place at these meetings, aIthough it is in no sense a symposium report.

The Biomedical Laser

The Biomedical Laser
Author: Leon Goldman
Publisher: Springer Science & Business Media
Total Pages: 341
Release: 2013-11-09
Genre: Technology & Engineering
ISBN: 1461259223
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The laser's range of application is extraordinary. Arthur Schawlow says, "What instrument can shuck a bucket of oysters, correct typing errors, fuse atoms, lay a straight line for a garden bed, repair detached retinas, and drill holes in dia monds?"O The laser's specifically biomedical uses cover a similarly broad and interesting spectrum. In this book, I have endeavored to convey some of the fas cination that the laser has long held for me. It is my hope that both clinicians and researchers in the various medical and surgical specialties will find the book a use ful introduction. Biologists, particularly molecular biologists, should also find a great deal of relevant information herein. This volume's distinguished contributors provide admirably lucid discussions of laser principles, instrumentation, and current practice in their respective special ties. Safety, design, capabilities, and costs of various lasers are also reviewed. We have aimed to create a practical text that is comprehensive but not exhaustive. Our emphasis on the practical, rather than the esoteric, is dictated not only by the short history of biomedical laser use, but by the extent of the community to which this information will appeal.

Applied Laser Medicine

Applied Laser Medicine
Author: H. Breuer
Publisher: Springer Science & Business Media
Total Pages: 762
Release: 2012-12-06
Genre: Medical
ISBN: 3642189792
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This handbook is intended for the advanced specialist and for the practitioner interested in the application of lasers in medicine. It provides summaries of all available medical laser systems and their clinical use. The first part introduces basic laser physics, including laser-tissue interactions as well as technical equipment and particular techniques developed for medical use in connection with laser. The second part of the text covers all areas of laser application in medicine and has been written by senior specialists from different countries. The book includes about 300 line drawings, more than 100 high quality photographs, an extensive subject and author register, and an exhaustive list of references.