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Interfacial Instability

Interfacial Instability
Author: Lewis E. Johns
Publisher: Springer Science & Business Media
Total Pages: 359
Release: 2007-05-08
Genre: Technology & Engineering
ISBN: 0387227016

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Essays are written to fulfill the needs of both teachers and graduate students; Problems have been selected so that they can be solved by hand; Discussion notes are at the end of many of the essays to serve as a basis for discussion; Endnotes provide background information which the reader may need in order to enjo the essay


Interfacial Instability

Interfacial Instability
Author: Lewis E. Johns
Publisher:
Total Pages: 364
Release: 2014-01-15
Genre:
ISBN: 9781475777352

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Protein Instability at Interfaces During Drug Product Development

Protein Instability at Interfaces During Drug Product Development
Author: Jinjiang Li
Publisher: Springer Nature
Total Pages: 338
Release: 2021-02-12
Genre: Medical
ISBN: 3030571777

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Proteins are exposed to various interfacial stresses during drug product development. They are subjected to air-liquid, liquid-solid, and, sometimes, liquid-liquid interfaces throughout the development cycle-from manufacturing of drug substances to storage and drug delivery. Unlike small molecule drugs, proteins are typically unstable at interfaces where, on adsorption, they often denature and form aggregates, resulting in loss of efficacy and potential immunogenicity. This book covers both the fundamental aspects of proteins at interfaces and the quantification of interfacial behaviors of proteins. Importantly, this book introduces the industrial aspects of protein instabilities at interfaces, including the processes that introduce new interfaces, evaluation of interfacial instabilities, and mitigation strategies. The audience that this book targets encompasses scientists in the pharmaceutical and biotech industry, as well as faculty and students from academia in the surface science, pharmaceutical, and medicinal chemistry areas.


A Study of the Interfacial Stability of Ti/Al2O3, Ti3Al/Al2O3 and TiAl/Al2O3 Composite Materials

A Study of the Interfacial Stability of Ti/Al2O3, Ti3Al/Al2O3 and TiAl/Al2O3 Composite Materials
Author: Joel Alan DeKock
Publisher:
Total Pages: 352
Release: 1995
Genre:
ISBN:

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This thesis is a study of the interfacial stability of the Ti-Base metal matrix composites Ti/Al2O3, Ti3Al/Al2O3 and TiAl/Al2O3. Interfacial stability is discussed in view of the importance of thermodynamics and kinetics as the primary considerations which govern the type of stability observed. From a thermodynamics approach, the application of phase equilibrium diagrams is essential in the design of composite systems. A classification system, with reference to phase equilibrium, is used to describe the type of interfacial stability observed for the composites studied. In addition, electron-probe microanalysis, atom-probe field ion microscopy and X-ray diffraction results are used to establish Ti-Al-O phase relations for the temperature range 900-to-1250 deg C. The kinetics of interfacial stability is discussed with particular attention given to the kinetic considerations; diffusion path, phase formation sequence, steady-state layer growth and interface morphology. Kinetic results in the form of parabolic growth constants and calculated interdiffusion coefficients are presented.


Liquid Interfacial Systems

Liquid Interfacial Systems
Author: Rudolph V. Birikh
Publisher: CRC Press
Total Pages: 389
Release: 2003-06-17
Genre: Science
ISBN: 0824755847

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Despite factoring in countless natural, biological, and industrial processes, fixed attention on the singular attributes and behavior of fluids near or at interfaces has not received enough attention in the surface science literature. Liquid Interfacial Systems assembles and analyzes concepts and findings as an inclusive summation of fluid-fluid interfacial phenomena. This book covers excitation, stabilization, and suppression of instability at liquid interfaces. From the influential original research and scholarship of leaders in the discipline comes a volume to impart and explain definitions, scales, governing equations, and boundary conditions used in liquid interfacial system research.


Interfacial Instability

Interfacial Instability
Author: William Terry Mitchell
Publisher:
Total Pages: 220
Release: 1964
Genre:
ISBN:

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Interfacial Phenomena

Interfacial Phenomena
Author: Clarence A. Miller
Publisher: CRC Press
Total Pages: 524
Release: 2007-10-08
Genre: Science
ISBN: 1420044435

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Since the publication of the first edition of Interfacial Phenomena, the interest in interfaces and surfactants has multiplied, along with their applications. Experimental and theoretical advances have provided scientists with greater insight into the structure, properties, and behavior of surfactant and colloid systems. Emphasizing equil


Coextrusion

Coextrusion
Author: D. Djordjevic
Publisher: iSmithers Rapra Publishing
Total Pages: 160
Release: 1992
Genre: Technology & Engineering
ISBN: 9780902348714

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This report reviews sheet and profile extrusion, wire and cable coating and co-injection, describing both the rheological and structural considerations and the design and selection of machinery. Problems of layer instability and the c094 of layer c098 are addressed, as well as the selection of polymers and the recyclability of coextruded scrap. An additional indexed section containing several hundred abstracts from the Rapra Polymer Library database provides useful references for further reading.


Extruding Plastics

Extruding Plastics
Author: D.V. Rosato
Publisher: Springer Science & Business Media
Total Pages: 798
Release: 1998-10-31
Genre: Technology & Engineering
ISBN: 9780412828102

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Worldwide, extrusion lines successfully process more plastics into prod ucts than other processes by consuming at least 36 wt% of all plastics. They continue to find practical solutions for new products and/ or prob lems to meet new product performances. This book, with its practical industry reviews, is a unique handbook (the first of its kind) that covers over a thousand of the potential combina tions of basic variables or problems with solutions that can occur from up-stream to down-stream equipment. Guidelines are provided for maxi mizing processing efficiency and operating at the lowest possible cost. It has been prepared with an awareness that its usefulness will depend greatly upon its simplicity and provision of essential information. It should be useful to: 0) those already extruding and desiring to obtain additional information for their line and/ or prOVide a means of reviewing other lines that can provide their line with operating improvements; (2) those processing or extruding plastics for the first time; (3) those consider ing going into another extrusion process; (4) those desiring additional information about employing the design of various products more effi ciently, with respect to both performance and cost; (5) those contemplat ing entering the business of extrusion; (6) those in new venture groups, materials development, and/ or market development; (7) those in disci plines such as nonplastics manufacturers, engineers, designers, quality control, financial, and management; and (8) those requiring a textbook on extrusion in trade schools and high schools or colleges.