Interesting Topics In Drug Metabolism PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Interesting Topics In Drug Metabolism PDF full book. Access full book title Interesting Topics In Drug Metabolism.
| Author | : Corina Ionescu |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 444 |
| Release | : 2006-02-28 |
| Genre | : Medical |
| ISBN | : 9781402041419 |
Download Drug Metabolism Book in PDF, ePub and Kindle
Drug Metabolism: Current Concepts provides a comprehensive understanding of the processes that take place following ingestion of a medicinal agent or xenobiotic, with an emphasis on the crucial role of metabolism (biotransformation). How a sound knowledge of these phenomena is incorporated into the design of effective new drug candidates is also explained. The user-friendly text focuses on concepts rather than extraneous details and is supported by many illustrated examples of biotransformations as well as frequent references to current critical reviews and articles highlighting the nature of research objectives in this vibrant area of medicinal development. The final topic on strategies for drug design relies on the background provided by the rest of the book. This book is ideally suited as an advanced text for courses in drug metabolism for students of medicine, pharmacy, pharmacology, biochemistry; and for courses in drug design and drug delivery for students of medicinal chemistry. It is also appropriate for professional seminars or courses that relate to the fate of a drug in the body, drug interactions, adverse reactions and drug design.
| Author | : Drug Metabolism Discussion Group |
| Publisher | : |
| Total Pages | : |
| Release | : |
| Genre | : |
| ISBN | : |
Download Interesting Topics in Drug Metabolism Book in PDF, ePub and Kindle
| Author | : Siamak Cyrus Khojasteh |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 222 |
| Release | : 2011-04-07 |
| Genre | : Medical |
| ISBN | : 1441956298 |
Download Drug Metabolism and Pharmacokinetics Quick Guide Book in PDF, ePub and Kindle
Drug Metabolism and Pharmacokinetics Quick Guide covers a number of aspects of drug assessment at drug discovery and development stages, topics such as pharmacokinetics, absorption, metabolism, enzyme kinetics, drug transporters, drug interactions, drug-like properties, assays and in silico calculations. It covers key concepts, with useful tables on physiological parameters (eg. blood flow to organs in x-species, expression and localization of enzymes and transporters), chemical structure, nomenclature, and moieties leading to bioactivation (with examples). Overall it includes a number of key topics useful at the drug discovery stage, which would serve as a quick reference with several examples from the literature to illustrate the concept.
| Author | : Dennis A. Smith |
| Publisher | : John Wiley & Sons |
| Total Pages | : 269 |
| Release | : 2012-05-14 |
| Genre | : Medical |
| ISBN | : 3527329544 |
Download Pharmacokinetics and Metabolism in Drug Design Book in PDF, ePub and Kindle
In this new edition of a bestseller, all the contents have been brought upto-date by addressing current standards and best practices in the assessment and prediction of ADMET properties. Although the previous chapter layout has been retained, substantial revisions have been made, with new topics such as pro-drugs, active metabolites and transporters covered in detail in a manner useful to the Drug Discovery scientist. The authors discuss the parameters and processes important for the absorption, distribution and retention of drug compounds in the body, plus the potential problems created by their transformation into toxic byproducts. While aimed at all those dealing professionally with the development and application of pharmaceutical substances, the readily comprehensible style makes this book equally suitable for students of pharmacy and related subjects. Uniquely comprehensive, the book relates physicochemistry and chemical structure to pharmacokinetic properties and ultimately drug efficacy and safety.
| Author | : James Paxton |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 310 |
| Release | : 2012-02-22 |
| Genre | : Medical |
| ISBN | : 9535100998 |
Download Topics on Drug Metabolism Book in PDF, ePub and Kindle
In order to avoid late-stage drug failure due to factors such as undesirable metabolic instability, toxic metabolites, drug-drug interactions, and polymorphic metabolism, an enormous amount of effort has been expended by both the pharmaceutical industry and academia towards developing more powerful techniques and screening assays to identify the metabolic profiles and enzymes involved in drug metabolism. This book presents some in-depth reviews of selected topics in drug metabolism. Among the key topics covered are: the interplay between drug transport and metabolism in oral bioavailability; the influence of genetic and epigenetic factors on drug metabolism; impact of disease on transport and metabolism; and the use of novel microdosing techniques and novel LC/MS and genomic technologies to predict the metabolic parameters and profiles of potential new drug candidates.
| Author | : Robert S. Rozman |
| Publisher | : |
| Total Pages | : 229 |
| Release | : 1981 |
| Genre | : Drugs |
| ISBN | : |
Download Fourth Annual Symposium on Interesting Topics in Drug Metabolism Book in PDF, ePub and Kindle
| Author | : Drug Metabolism Discussion Group |
| Publisher | : |
| Total Pages | : |
| Release | : |
| Genre | : |
| ISBN | : |
Download Special Topics in Drug Metabolism Book in PDF, ePub and Kindle
| Author | : Mino R. Caira |
| Publisher | : Springer |
| Total Pages | : 422 |
| Release | : 2006-02-28 |
| Genre | : Medical |
| ISBN | : 9781402041419 |
Download Drug Metabolism Book in PDF, ePub and Kindle
Drug Metabolism: Current Concepts provides a comprehensive understanding of the processes that take place following ingestion of a medicinal agent or xenobiotic, with an emphasis on the crucial role of metabolism (biotransformation). How a sound knowledge of these phenomena is incorporated into the design of effective new drug candidates is also explained. The user-friendly text focuses on concepts rather than extraneous details and is supported by many illustrated examples of biotransformations as well as frequent references to current critical reviews and articles highlighting the nature of research objectives in this vibrant area of medicinal development. The final topic on strategies for drug design relies on the background provided by the rest of the book. This book is ideally suited as an advanced text for courses in drug metabolism for students of medicine, pharmacy, pharmacology, biochemistry; and for courses in drug design and drug delivery for students of medicinal chemistry. It is also appropriate for professional seminars or courses that relate to the fate of a drug in the body, drug interactions, adverse reactions and drug design.
| Author | : Wen Xie |
| Publisher | : Academic Press |
| Total Pages | : 296 |
| Release | : 2016-09-12 |
| Genre | : Medical |
| ISBN | : 0128029633 |
Download Drug Metabolism in Diseases Book in PDF, ePub and Kindle
Drug Metabolism in Diseases is a comprehensive reference devoted to the current state of research on the impact of various disease states on drug metabolism. The book contains valuable insights into mechanistic effects and examples of how to accurately predict drug metabolism during these different pathophysiological states. Each chapter clearly presents the effects of changes in drug metabolism and drug transporters on pharmacokinetics and disposition. This is a unique and useful approach for all those involved in drug discovery and development, and for clinicians and researchers in drug metabolism, pharmacology, and clinical pharmacology. Written and edited by leaders in drug metabolism from academia and industry Covers important topics, such as pharmacogenomics, drug metabolism in transplant patients, xenobiotic receptors, drug metabolism in geriatric and pediatric populations, and more Highlights topics of importance in drug discovery and development, and for safe and effective drug use in the clinic
| Author | : Alexander Lyubimov |
| Publisher | : Anchor Books |
| Total Pages | : 631 |
| Release | : 2012 |
| Genre | : Drug interactions |
| ISBN | : 9781118149751 |
Download Encyclopedia of Drug Metabolism and Interactions Book in PDF, ePub and Kindle
This multi-volume, state-of-the-art encyclopedia discusses all preclinical, clinical, toxicological, regulatory and marketing perspectives of drug metabolism and interactions. Methods and detailed protocols describing how to perform studies of metabolism and drug interactions are presented in one of the volumes. All aspects of drug metabolism and interactions in silico, in laboratory animals and in humans, are backed with a range of examples. This reference is essential for researchers interested in all aspects of drug development, and chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular toxicologists, and clinicians including practitioners and physicians.
