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Neuroendocrine-immune Interactions

Neuroendocrine-immune Interactions
Author: Rolf C. Gaillard
Publisher: Karger Medical and Scientific Publishers
Total Pages: 144
Release: 2002
Genre: Medical
ISBN: 3805572824

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Interactions between the immune, endocrine and nervous systems seldom appear as main issues in the neurosciences and in immunology. So far this was most likely due to the need to focus on the molecular and cellular bases of single neural, endocrine and immune processes. But hormones, neurotransmitters and neuropeptides can also influence more subtle mechanisms underlying immune cell activity. The contents of this volume aim at listing some aspects which show that not only the bases for neuroendocrine control of more refined mechanisms related to the organization and functioning of the immune systems to exist, but also that the immune system can actively communicate with neuroendocrine structures. The evidence is divided into three categories: - Anatomical, cellular and molecular bases for the exchange of information between immune, endocrine and neural cells, - reciprocal effects between immune and neuroendocrine mechanisms, and - immune-neuroendocrine regulatory circuits. Immunologically triggered neuroendocrine responses can be either beneficial or deleterious for the host. A systematic approach would imply the simultaneous evaluation of neuroendocrine and immune parameters and thus provide the basis for therapeutic interventions based on antagonizing or blocking undesirable effects.


Neuroendocrine-Immune System Interactions

Neuroendocrine-Immune System Interactions
Author: Jan Pieter Konsman
Publisher: Springer Nature
Total Pages: 393
Release: 2023-03-03
Genre: Medical
ISBN: 3031213580

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The concepts of the neuroendocrine system and the immune system emerged more or less simultaneously in the second half of the 20th century. Although these systems have a high degree of autonomy, it has also become clear that they interact in many ways and at different levels. This book focuses on the neuroendocrine and immune interactions that are fundamental to normal development and maintenance of health. The first introductory chapters are devoted to the historical and philosophical concepts within the field, as well as evolutionary considerations, offering critical interdisciplinary perspectives on the development of this field of research. Without attempting an exhaustive overview, the book then introduces some of the regulatory pathways that mediate interactions between the neuroendocrine and immune systems and examines modulating factors such as age and sex. In addition, several chapters address the importance of neuroendocrine-immune interactions in some disease states. Readers can expect to gain a broad perspective of neuroendocrine-immune interactions in development, health, and disease, along with a critical evaluation of current methods used in the field. Given its scope, the book is essential reading for undergraduate and graduate students with an interest in neuroendocrinology, neuroimmunology, and neuroscience, as well as postdoctoral fellows and established researchers seeking a comprehensive overview and historical perspective of the field of neuroendocrine-immune interactions.


An Introduction to Neuroendocrinology

An Introduction to Neuroendocrinology
Author: Richard E. Brown
Publisher: Cambridge University Press
Total Pages: 434
Release: 1994-01-27
Genre: Science
ISBN: 9780521426657

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This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.


The Neuroendocrine Immune Network

The Neuroendocrine Immune Network
Author: S. Freier
Publisher: CRC Press
Total Pages: 278
Release: 2018-01-18
Genre: Medical
ISBN: 1351085646

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This informative publication updates the study of interaction of the nervous and endocrine systems with the immune system in the body. It describes the anatomical basis of these interactions, reviewing the innervation of lymphoid tissue and mast cells. The book discusses the effect of the endocrine system on immune function, including the relation of sex to the immune response. Emphasis is given to opioids, substance P, neurotensin, vasoactive intestinal peptide, somatostatin and cholecystokinin. Also addressed is the immunoregulatory effect of leukotrienes and platelet-activating factors. Scrutinized within are stress as an aspect of neuro-immune interactions, and the central role of the hypothalamus in this context. The book reviews the eye and the gastrointestinal tract with respect to the coordination of the nervous, endocrine, and immune systems in serving these organs. This work is of particular value to those in immunology, endocrinology, gastroenterology, and developmental biology.


Neuroendocrine-Immune Interactions

Neuroendocrine-Immune Interactions
Author: Rolf C. Gaillard
Publisher:
Total Pages: 0
Release: 2001
Genre: Medical
ISBN: 9783318007558

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Interactions between the immune, endocrine and nervous systems seldom appear as main issues in the neurosciences and in immunology. So far this was most likely due to the need to focus on the molecular and cellular bases of single neural, endocrine and immune processes. But hormones, neurotransmitters and neuropeptides can also influence more subtle mechanisms underlying immune cell activity. The contents of this volume aim at listing some aspects which show that not only the bases for neuroendocrine control of more refined mechanisms related to the organization and functioning of the immune systems do exist, but also that the immune system can actively communicate with neuroendocrine structures. The evidence is divided into three categories: - anatomical, cellular and molecular bases for the exchange of information between immune, endocrine and neural cells - reciprocal effects between immune and neuroendocrine mechanisms - immune-neuroendocrine regulatory circuits Immunologically triggered neuroendocrine responses can be either beneficial or deleterious for the host. A systematic approach would imply the simultaneous evaluation of neuro-endocrine and immune parameters and thus provide the basis for therapeutic interventions based on antagonizing or blocking undesirable effects.


Psychoneuroimmunology

Psychoneuroimmunology
Author:
Publisher: Elsevier
Total Pages: 1291
Release: 2011-10-10
Genre: Science
ISBN: 0080465013

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Psychoneuroimmunology is the study of interactions among behavioral, neural and endocrine, and immunologic processes of adaptation. These two volumes provide a clearly written, extensively referenced summary of some of the behavioral, neural and endocrine regulators of immune responses and immunologically mediated disease processes and of the behavioral and neuroendocrine effects of immune system activity. Several chapters expand upon topics reviewed in earlier editions of this series; most chapters cover active areas of research that have not previously been reviewed. As illustrated in this fourth edition, interdisciplinary research continues to provide evidence that the brain and immune system represent a single, integrated system of defense. Fully revised and updated fourth edition of the classic reference Provides a neuroendocrine and immunologic perspective for the behavioral scientist Provides a behavioral and neuroscience perspective for the immunologist Helps the reader translate basic science findings into clinically relevant information Provides the reader with the background for and foundation of integrative research and integrative medicine Provides an encyclopedic resource for advanced undergraduates and for pre- and post-doctoral students as well as active researchers


Handbook of Human Stress and Immunity

Handbook of Human Stress and Immunity
Author: Ronald Glaser
Publisher: Academic Press
Total Pages: 436
Release: 2014-06-28
Genre: Medical
ISBN: 1483295125

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In 1964, George Solomon coined the term psychoneuroimmunology. In the intervening 30 years, this term has emerged into a dynamic field of study which investigates the unique interactions between the nervous, endocrine, and immune systems. The Handbook of Human Stress and Immunity is a comprehensive reference for this dynamic new field. Focusing on how stressors impact the central nervous system and the resulting changes in immune responses, the Handbook is the first to describehow stress specifically affects human immune systems. It discusses how stress generally makes people more susceptible to infection, how personal support systems can counteract the physiological effects of stress, and how stress, or lack of stress, affects the aging process. Chapters are authored by the leading names in the field and cover such diseases as autoimmune disease, viral pathogenesis, herpes, HIV, and AIDS.


Psychoimmunology

Psychoimmunology
Author: Alan J. Husband
Publisher: CRC Press
Total Pages: 192
Release: 1993-03-24
Genre: Medical
ISBN: 9780849348792

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Psychoimmunology: CNS-Immune Interactions is based on papers presented at the Second International Scientific Meeting of the Australian Behavioral Immunology Group, held at the University of Newcastle in Australia on March 7 and 8, 1992. Information featured in the volume confirms the longstanding perception that state of mind and behavioral patterns have an impact on general health. Clinicians discuss correlations between lifestyle, stress, and disease, while scientists reveal their findings on ways in which deliberate manipulations of the central nervous systems and behavioral patterns are reflected in changes in immunological outcome. Other papers present findings regarding the mediators of these interactions, which include cytokines, hormones, and neurotransmitters. Psychoimmunology: CNS-Immune Interactions will be a useful reference for psychoimmunologists, immunologists, psychologists, microbiologists, and all medical and behavioral scientists interested in the links between brain behavior and disease.


The Brain Immune Axis and Substance Abuse

The Brain Immune Axis and Substance Abuse
Author: Burt M. Sharp
Publisher: Springer
Total Pages: 0
Release: 2012-10-21
Genre: Medical
ISBN: 9781461358015

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This volume represents the proceedings of the 2nd annual symposium on the Brain Immune Axis and Substance Abuse held at the Breakers Hotel in Palm Beach, FL in June 1994. The history of productive studies concerning the relationship between the nervous and the immune systems is relatively recent. Studies on the effects of drugs of abuse on the immune system and on infections among individuals who abuse drugs are also of recent vintage. Only in the last decade have investigators begun to describe the role of drugs of abuse and their endogenous counterparts on the brain-immune axis. Thus, the involvement of the neuroendocrine system in the interactions of drugs of abuse and the immune system has only recently been appreciated. In addition, it has been recognized that direct neural inputs impact immune function. Given the complexity of these interactions, characterization of biologically significant phenomena and elucidation of their mechanisms of action often requires a multidisciplinary approach. This meeting, on which the chapters in this book are based, brought together scientists from an array of biomedical disciplines whose work is focused on the effects of drugs of abuse on the neuro-endocrine immune axis. The meeting was unique in focusing on the brain-immune axis from the viewpoint of drugs of abuse rather than either immunity itself or the brain itself. Presentations addressed the direct effects of drugs of abuse on various components of the immune system, as well as those mediated indirectly by the central nervous system and the neuroendocrine system.