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Understanding Insulin and Insulin Resistance

Understanding Insulin and Insulin Resistance
Author: Anil Gupta
Publisher: Elsevier
Total Pages: 321
Release: 2021-11-17
Genre: Medical
ISBN: 012820379X

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Understanding Insulin and Insulin Resistance is written in a simple and clear language illustrated with diagrams that show the complex interplay of various factors in the initiation of insulin resistance. The design is systematic and meticulous, portraying topics in a flow from simple to complex. This resource is intended for a broad audience spanning across biochemistry, medicine, dentistry, academia, physicians, and research scholars. It extends the approach to biochemistry, physiology, metabolism of insulin along with the coverage of pathophysiology of insulin resistance, its effects on the body tissues, and its analysis on insulin resistance syndrome.


Insulin Action

Insulin Action
Author: Ashok K. Srivastava
Publisher: Springer Science & Business Media
Total Pages: 206
Release: 1998-05-31
Genre: Science
ISBN: 9780792381136

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In 1996 the 75th anniversary of the discovery of insulin was celebrated at the University of Toronto, the scene of that discovery in 1921. This volume was stimulated by the scientific program which was staged at that time and brought together much of the world's best talent to discuss and analyze the most recent developments in our understanding of pancreatic function, insulin secretion, the interaction of insulin with its target tissues, the mechanism of insulin action at the cellular level, and the defects which underlie both Type I (insulin-dependent diabetes mellitus, IDDM) and Type II (noninsulin-dependent diabetes mellitus, NIDDM) forms of the disease. We have chosen to focus the present volume on work related to insulin action.


The Discovery of Insulin

The Discovery of Insulin
Author: Michael Bliss
Publisher: University of Toronto Press
Total Pages: 320
Release: 2017-06-22
Genre: Medical
ISBN: 1487516746

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The discovery of insulin at the University of Toronto in 1921-22 was one of the most dramatic events in the history of the treatment of disease. Insulin was a wonder-drug with ability to bring patients back from the very brink of death, and it was no surprise that in 1923 the Nobel Prize for Medicine was awarded to its discoverers, the Canadian research team of Banting, Best, Collip, and Macleod. In this engaging and award-winning account, historian Michael Bliss recounts the fascinating story behind the discovery of insulin – a story as much filled with fiery confrontation and intense competition as medical dedication and scientific genius. Originally published in 1982 and updated in 1996, The Discovery of Insulin has won the City of Toronto Book Award, the Jason Hannah Medal of the Royal Society of Canada, and the William H. Welch Medal of the American Association for the History of Medicine.


Using Insulin

Using Insulin
Author: John Walsh
Publisher:
Total Pages: 0
Release: 2003
Genre: Health & Fitness
ISBN: 9781884804854

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Using Insulin shows how to set, test, and adjust fast-acting and long-acting insulin doses for those with Type 1 or Type 2 diabetes. It covers Lantus, Detemir, Humalog and Novolog insulins. Helpful chapters explain carb counting, the glycemic index, safe exercise, insulin use in pregnancy and gestational diabetes, combining insulin with diabetes medications, dosage guidelines for children and teens, prevention and treatment for highs and lows, and reversing hypoglycemia unawareness.


Galenics of Insulin

Galenics of Insulin
Author: Jens Brange
Publisher: Springer Science & Business Media
Total Pages: 108
Release: 2012-12-06
Genre: Medical
ISBN: 3662025264

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Galenical pharmacy or galenics is the science dealing with the pro duction of drug substances from raw materials, the purity of such substances, their formulation into pharmaceutical preparations with the desired effects and safety in use, and the quality control, stability and storage of the preparations. The field has taken its name from the Greek physician Galen (131-201 A.D.), who had a profound influence on medicine for many centuries because he collected and systematized the medicinal knowledge of his time. The discovery of insulin is attributed to Banting and Best who, in 1921, prepared an extract of the pancreas of the fetal calf and showed that the extract was capable of reducing the blood sugar level of a diabetic dog. This outstanding discovery gave rise to the rapid develop ment of the manufacture of insulin of bovine and porcine origin. By 1925, two Danish manufacturers of insulin preparations were established; both have since been in the forefront ofthe development of insulin preparations, the latest achievement being the marketing of human insulin by Novo in 1982. The development of highly purified human insulin produced semisynthetically from porcine insulin or by DNA recombinant methods are significant contributions to safe and efficient insulin therapy. Insulin is a protein which is destroyed in the gastrointestinal tract.


Hypoglycemia in Diabetes

Hypoglycemia in Diabetes
Author: Philip Cryer
Publisher: American Diabetes Association
Total Pages: 194
Release: 2016-07-12
Genre: Medical
ISBN: 1580406491

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Intended for diabetes researchers and medical professionals who work closely with patients with diabetes, this newly updated and expanded edition provides new perspectives and direct insight into the causes and consequences of this serious medical condition from one of the foremost experts in the field. Using the latest scientific and medical developments and trends, readers will learn how to identify, prevent, and treat this challenging phenomenon within the parameters of the diabetes care regimen.


Insulin Resistance

Insulin Resistance
Author: Gerald M. Reaven
Publisher: Springer Science & Business Media
Total Pages: 388
Release: 1999-04
Genre: Medical
ISBN: 9780896035881

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In Insulin Resistance: The Metabolic Syndrome X, outstanding investigators thoughtfully summarize our current understanding of how insulin resistance and its compensating hyperinsulinemia (Syndrome X) play a major role in the pathogenesis and clinical course of high blood pressure and cardiovascular disease-the so-called diseases of Western civilization-as well as polycystic ovary disease. Under the aegis of Gerald Reaven, the discoverer of Syndrome X, the distinguished authorities writing here detail for the first time the pathophysiological consequences and the clinical syndromes, excluding Type 2 diabetes, related to insulin resistance. They also examine the genetic and lifestyle factors that contribute to the wide differences in insulin action that exist in the population at large. Each author has been encouraged to present a point of view that reflects their unique insights. The first authoritative book on the subject, Insulin Resistance: The Metabolic Syndrome X illuminates the special importance of insulin resistance as a major cause of hypertension, heart disease, and polycystic ovary syndrome. Its thoughtful and detailed approach will make it an essential reference for basic and clinical researchers seeking to understand these critical phenomena.


Breakthrough

Breakthrough
Author: Thea Cooper
Publisher: Macmillan + ORM
Total Pages: 319
Release: 2010-09-14
Genre: Medical
ISBN: 142996569X

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It is 1919 and Elizabeth Hughes, the eleven-year-old daughter of America's most-distinguished jurist and politician, Charles Evans Hughes, has been diagnosed with juvenile diabetes. It is essentially a death sentence. The only accepted form of treatment – starvation – whittles her down to forty-five pounds skin and bones. Miles away, Canadian researchers Frederick Banting and Charles Best manage to identify and purify insulin from animal pancreases – a miracle soon marred by scientific jealousy, intense business competition and fistfights. In a race against time and a ravaging disease, Elizabeth becomes one of the first diabetics to receive insulin injections – all while its discoverers and a little known pharmaceutical company struggle to make it available to the rest of the world. Relive the heartwarming true story of the discovery of insulin as it's never been told before. Written with authentic detail and suspense, and featuring walk-ons by William Howard Taft, Woodrow Wilson, and Eli Lilly himself, among many others.


Think Like a Pancreas

Think Like a Pancreas
Author: Gary Scheiner
Publisher: Da Capo Lifelong Books
Total Pages: 205
Release: 2012-01-24
Genre: Health & Fitness
ISBN: 0738215376

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The all-in-one, comprehensive resource for the millions of people with diabetes who use insulin, revised and updated. Few diabetes books focus specifically on the day-to-day issues facing people who use insulin. Diabetes educator Gary Scheiner provides the tools to "think like a pancreas" -- to successfully master the art and science of matching insulin to the body's ever-changing needs. Comprehensive, free of medical jargon, and packed with useful information not readily available elsewhere, such as: Day-to-day blood glucose control and monitoring Designing an insulin program to best match your lifestyle Up-to date medication and technology New insulin formulations and combinations and more With detailed information on new medications and technologies -- both apps and devices -- surrounding insulin, as well as new injection devices, and dietary recommendations, Think Like a Pancreas is the insulin user's go-to guide.


Mechanisms of Insulin Action

Mechanisms of Insulin Action
Author: Alan R. Saltiel
Publisher: Springer Science & Business Media
Total Pages: 223
Release: 2007-10-05
Genre: Medical
ISBN: 0387722041

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More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.