Inositol Lipids In Cellular Signaling PDF Download
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| Author | : R. H. Michell |
| Publisher | : |
| Total Pages | : 568 |
| Release | : 1989 |
| Genre | : Science |
| ISBN | : |
Download Inositol Lipids in Cell Signalling Book in PDF, ePub and Kindle
The discovery that inositol lipids are integral in cellular signaling mechanisms has been one of the most exciting breakthroughs in recent years. As secondary messengers in a wide variety of tissues and involved processes as diverse as rapid contraction of skeletal muscle, insulin secretion, and the slow activation of cell proliferation in cancer cells, their impact on biochemistry is akin to that of cyclic AMP two decades ago. Drawing together the many strands of research on inositol lipid-mediated signalling and containing contributions by leading authorities in their fields, Inositol Lipids in Cell Signalling is essential for any involved biochemist, cell biologist, or pharmacologist.
| Author | : R. H. Michell |
| Publisher | : Cold Spring Harbor Laboratory Press |
| Total Pages | : 184 |
| Release | : 1987 |
| Genre | : Biochemistry |
| ISBN | : |
Download Inositol Lipids in Cellular Signaling Book in PDF, ePub and Kindle
| Author | : John N. Fain |
| Publisher | : Academic Press |
| Total Pages | : 376 |
| Release | : 2013-10-22 |
| Genre | : Science |
| ISBN | : 1483288323 |
Download Lipid Metabolism in Signaling Systems Book in PDF, ePub and Kindle
Many of the phospholipases and even the receptor for inositol 1,4,5-trisphosphate have recently been cloned and sequenced and play an important role in neurotransmission. Methods developed in recent years for the study of the enzymes and intermediates involved in the regulation of neuronal signal transduction involving phospholipid turnover are presented in this volume. Techniques for examining the role of phosphoinositides in signal transduction Techniques related to protein kinase C Analysis of inositol phosphates Techniques to analyze phospholipid turnover in the brain
| Author | : A. Kuksis |
| Publisher | : Elsevier |
| Total Pages | : 1002 |
| Release | : 2003-09-12 |
| Genre | : Science |
| ISBN | : 0444513213 |
Download Inositol Phospholipid Metabolism and Phosphatidyl Inositol Kinases Book in PDF, ePub and Kindle
Offers a review of developments along with tried and tested methods for isolation, resolution and quantification of inositol phospholipids and inositol polyphosphates in both cells and tissues. This book includes detailed methodology for identification of molecular species of inositol phospholipids, including their phosphates and glycans.
| Author | : Xuemin Wang |
| Publisher | : Frontiers E-books |
| Total Pages | : 249 |
| Release | : 2013-07-30 |
| Genre | : |
| ISBN | : 2889191486 |
Download Lipid signaling in plants Book in PDF, ePub and Kindle
Cell membranes are the initial and focal sites of stimulus perception and signal transduction. Membrane lipids are rich sources for the production of signaling messengers that mediate plant growth, development, and response to nutrient status and stresses. In recent years, substantial progress has been made toward understanding lipid signaling in plants, but many fundamental questions remain: What lipids are signaling messengers or mediators in plants? How are the signaling lipids produced and metabolized? In what plant cellular and physiological processes are various lipid mediators involved? How do they carry out their signaling functions? How do lipid signaling networks contribute to modulating plant growth, development, and responses to hormones and stresses? In this Research Topic issue, we invite the broad plant community to address the above questions.Cell membranes are the initial and focal sites of stimulus perception and signal transduction. Membrane lipids are rich sources for the production of signaling messengers that mediate plant growth, development, and response to nutrient status and stresses. In recent years, substantial progress has been made toward understanding lipid signaling in plants, but many fundamental questions remain: What lipids are signaling messengers or mediators in plants? How are the signaling lipids produced and metabolized? In what plant cellular and physiological processes are various lipid mediators involved? How do they carry out their signaling functions? How do lipid signaling networks contribute to modulating plant growth, development, and responses to hormones and stresses? In this Research Topic issue, we invite the broad plant community to address the above questions.
| Author | : Bruce Alberts |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2002 |
| Genre | : Cytology |
| ISBN | : 9780815332183 |
Download Molecular Biology of The Cell Book in PDF, ePub and Kindle
| Author | : M.P. Mattson |
| Publisher | : Elsevier |
| Total Pages | : 237 |
| Release | : 2003-05-06 |
| Genre | : Science |
| ISBN | : 0080522505 |
Download Membrane Lipid Signaling in Aging and Age-Related Disease Book in PDF, ePub and Kindle
The lipids of cellular membranes not only serve roles in controlling the structure and fluidity of the membrane, but are increasingly recognized for their roles as signalling molecules and modifiers of membrane protein function. Recent studies described in this volume reveal striking changes in membrane lipids during aging and in age-related diseases such as cancer, cardiovascular disease and neurodegenerative disorders. Lipids including inositol phospholipids, cholesterol, sphingolipids and ceramides play important roles in signalling cellular responses to stress and specific stimuli such as growth factors, cytokines and neurotransmitters. One or more of these lipid mediators has been linked to the pathogenesis of age-related diseases. This book provides a comprehensive review of specific membrane lipid mediators and their roles in aging and age-related disease.
| Author | : Jose M. Mato |
| Publisher | : CRC Press |
| Total Pages | : 225 |
| Release | : 2018-01-18 |
| Genre | : Medical |
| ISBN | : 1351092421 |
Download Phospholipid Metabolism in Cellular Signaling Book in PDF, ePub and Kindle
Phospholipids are no longer considered exclusively as the building blocks of biomembranes, but are now regarded to be exceptionally important to cellular signalling.Another conclusion resulting from studies over the past several years is that no single general scheme for the role of phospholipids during cell activation can be drawn as representative of all cells. This book presents a comprehensive view of the recent advances made in certain major research areas within the field of phospholipid metabolism in cellular signalling. Topics discussed within this volume include lipid composition of cellular membranes and their organization in biological systems, the dynamic aspects of phospholipid metabolism and its regulation by extracellular stimuli, and the role of newly discovered glycosyl-phosphatidylinositols in insulin action . The book also discusses two biologically active phospholipids: the sphingolipids, and ether-linked glycerophospholipids (the platelet activating factor). Phospholipid Metabolism in Cellular Signaling is an important research reference that should be considered required reading by all scientists and graduate students working on cell activation (e.g., growth factors, hormones, and oncogenes).
| Author | : |
| Publisher | : Elsevier |
| Total Pages | : 387 |
| Release | : 2007-11-12 |
| Genre | : Science |
| ISBN | : 0080554091 |
Download Lipidomics and Bioactive Lipids: Lipids and Cell Signaling Book in PDF, ePub and Kindle
This volume in the well-established Methods in Enzymology series features methods for the study of lipids using mass spectrometry techniques. Articles in this volume cover topics such as Phospholipase A1 assays using a radio-labeled substrate and mass spectrometry; Real-time Cell Assays of Phospholipases A2 Using Fluorogenic Phospholipids; Analysis and Pharmacological Targeting of Phospholipase C â interactions with G proteins; Biochemical Analysis of Phospholipase D.; Measurement of Autotaxin/Lysophospholipase D Activity; Platelet-Activating Factor; Quantitative measurement of PtdIns(3,4,5)P3; Measuring Phosphorylated Akt And Other Phosphoinositide 3-Kinase-Regulated Phosphoproteins In Primary Lymphocytes; Regulation of Phosphatidylinositol 4-Phosphate 5-Kinase activity by partner proteins; Biochemical Analysis of Inositol Phosphate Kinases; Analysis of the phosphoinositides and their aqueous metabolites; Combination of C17-sphingoid base homologues and mass spectrometry analysis as a new approach to study sphingolipid metabolism; Measurement of mammalian sphingosine-1-phosphate phosphohydrolase activity in vitro and in vivo; A rapid and sensitive method to measure secretion of sphingosine-1-phosphate; Ceramide Kinase and Ceramide-1-Phosphate; Measurement of Mammalian Diacylglycerol Kinase Activity in vitro and in Cells; Lipid Phosphate Phosphatases from Saccharomyces cerevisiae.
| Author | : Daniel G.S. Capelluto |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 227 |
| Release | : 2013-06-17 |
| Genre | : Medical |
| ISBN | : 940076331X |
Download Lipid-mediated Protein Signaling Book in PDF, ePub and Kindle
This book provides the most updated information of how membrane lipids mediate protein signaling from studies carried out in animal and plant cells. Also, there are some chapters that go beyond and expand these studies of protein-lipid interactions at the structural level. The book begins with a literature review from investigations associated to sphingolipids, followed by studies that describe the role of phosphoinositides in signaling and closing with the function of other key lipids in signaling at the plasma membrane and intracellular organelles.
