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Inflammation in Psychiatry

Inflammation in Psychiatry
Author: A. Halaris
Publisher: Karger Medical and Scientific Publishers
Total Pages: 218
Release: 2013-02-27
Genre: Medical
ISBN: 3318023116

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Psychoimmunology is a rapidly maturing area of scientific endeavor that provides a compelling integrative link between the immune system and its response to stress and psychiatric illness. Stress initiates pathological changes by activating the immune and endocrine systems. Inflammation is at the core of the complex and interactive systems that both contribute to and result from psychopathology. Consequently, inflammation research advances our knowledge of the pathology of depression, schizophrenia, chronic fatigue syndrome, posttraumatic stress disorder and a host of co-morbid conditions, notably diabetes, cardiovascular disease and cerebrovascular disease. The possible mechanisms underlying the bidirectionality of co-morbid medical and psychiatric disorders can be viewed as a consequence of inflammatory changes. These emerging novel concepts illustrate how the knowledge of inflammation can enable meaningful integration of psychopathology with physical co-morbidity. The innovative articles in this volume highlight the intricate link between psychiatry and psychoimmunology and underscore the central role of inflammation in furthering our understanding of the pathophysiology underlying mental health and illness.


Inflammation in Neuropsychiatric Disorders

Inflammation in Neuropsychiatric Disorders
Author: Rossen Donev
Publisher: Academic Press
Total Pages: 202
Release: 2012-08-02
Genre: Medical
ISBN: 0123983142

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Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics. Covers reviews of methodology and research in all aspects of protein chemistry Brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics


Inflammation-Associated Depression: Evidence, Mechanisms and Implications

Inflammation-Associated Depression: Evidence, Mechanisms and Implications
Author: Robert Dantzer
Publisher: Springer
Total Pages: 357
Release: 2016-12-28
Genre: Medical
ISBN: 3319511521

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Inflammation has invaded the field of psychiatry. The finding that cytokines are elevated in various affective and psychotic disorders brings to the forefront the necessity of identifying the precise research domain criteria (RDoCs) that inflammation is responsible for. This task is certainly the most advanced in major depressive disorders. The reason is that a dearth of clinical and preclinical studies has demonstrated that inflammation can cause symptoms of depression and conversely, cytokine antagonists can attenuate symptoms of depression in medical and psychiatric patients with chronic low grade inflammation. Important knowledge has been gained on the symptom dimensions that inflammation is driving and the mechanisms of action of cytokines in the brain, providing new targets for drug research and development. The aim of the book “Inflammation-Associated Depression” is to present this field of research and its implications in a didactic and comprehensive manner to basic and clinical scientists, psychiatrists, physicians, and students at the graduate level.


The Role of Inflammation in the Etiology and Treatment of Schizophrenia

The Role of Inflammation in the Etiology and Treatment of Schizophrenia
Author: Ole Köhler-Forsberg
Publisher: Frontiers Media SA
Total Pages: 130
Release: 2020-12-23
Genre: Medical
ISBN: 2889662691

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.


Mechanisms of Neuroinflammation

Mechanisms of Neuroinflammation
Author: Gonzalo Emiliano Aranda Abreu
Publisher: BoD – Books on Demand
Total Pages: 320
Release: 2017-08-23
Genre: Medical
ISBN: 9535134515

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"Mechanisms of Neuroinflammation" book explains how the neuronal cells become swollen at the moment of the blood-brain barrier disruption and how they lose their immunological isolation. A cascade of cytokines and immune cells from the bloodstream enters the nervous system, inflaming neurons and activating the glia. This produces a neuroinflammatory process that can generate different neurodegenerative diseases. Better understanding of mechanisms that are activated at the time when the damage to the brain occurs could lead to the development of suitable therapies that revert the neuronal inflammation and thus prevent further damage to the nervous system.


Neuroinflammation and Cognition

Neuroinflammation and Cognition
Author: Ashok Kumar
Publisher: Frontiers Media SA
Total Pages: 191
Release: 2019-03-22
Genre:
ISBN: 2889457605

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Aging is one of the major risk factors for the onset and progression of various neurodegenerative diseases. Neuroinflammation is a common feature of virtually every central nervous system disease, and is acknowledged as a likely mediator of cognitive impairments. Systemic inflammation levels are augmented with advanced age and neurodegeneration. The influence of age on neuroinflammatory responses including glial activation, increased production of proinflammatory cytokines, and aberrant neuronal signaling could magnify the deterioration of the central nervous system microenvironment in disease, and may contribute to enhanced cognitive impairment. This eBook is a collection of highly informative original research articles, providing comprehensive aspect of neuroinflammation and possible therapeutic interventions in rescuing cognitive impairments.


Inflammation and Oxidative Stress in Neurological Disorders

Inflammation and Oxidative Stress in Neurological Disorders
Author: Akhlaq A. Farooqui
Publisher: Springer Science & Business Media
Total Pages: 355
Release: 2014-01-27
Genre: Medical
ISBN: 3319041118

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Unless new discoveries are made in the prevention or treatment of stroke, Alzheimer's Disease and depression, the number of patients with these diseases is sure to increase dramatically by the year 2050. Thus, developing strategies to retard or delay the onset of stroke, AD and depression these neurological disorders is of critical important. The present monograph will provide current and comprehensive information on the relationship between neuroinflammation and oxidative stress in age-related neurological disorders at the molecular level. The information described in this monograph on lifestyle (diet and exercise), genes and age is intended to facilitate and promote new discoveries for the treatment of age-related neurological disorders.


Perinatal Inflammation and Adult Psychopathology

Perinatal Inflammation and Adult Psychopathology
Author: Antonio L. Teixeira
Publisher: Springer Nature
Total Pages: 276
Release: 2020-04-07
Genre: Medical
ISBN: 3030393356

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Perinatal psychiatry is an emerging field that investigates the role of perinatal events – for example pregnancy complications and infections – in the development of neuropsychiatric conditions, such as schizophrenia and mood disorders. Among the implicated pathological mechanisms, perinatal-induced inflammation seems to play a major role and is being considered as a potential target for therapeutic intervention. Bringing together various approaches in the field (preclinical and clinical, epidemiological, immunological and genetic methods), the book discusses the available evidence, the putative mechanisms and the challenges ahead.


Neuroinflammation, Gut-Brain Axis and Immunity in Neuropsychiatric Disorders

Neuroinflammation, Gut-Brain Axis and Immunity in Neuropsychiatric Disorders
Author: Yong-Ku Kim
Publisher:
Total Pages: 0
Release: 2023
Genre:
ISBN: 9789811973772

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This book reviews the relationship between cytokines, glia, and neurons in the pathophysiology of neuropsychiatric disorders and examines the mechanisms of action of the drugs used for the treatment of these disorders. Increasing evidence has suggested that glia perform important roles in various brain functions, but much remains to be learned about these crucial cells and their interplay with neurons. In addition, a better understanding of the interaction between inflammatory mediators, such as cytokines, and the activated immune response will be of critical importance for the development of new therapeutic strategies. These key areas are the focus of this book, which documents the latest research findings in the field. Evidence is provided for the role of inflammation-induced toxic metabolites from the tryptophan pathway in a wide range of neuropsychiatric disorders, including depression, schizophrenia, and Alzheimer's disease. In presenting state of the art knowledge on the interactions between cytokines, glia, and neurons, the book will help to pave the way for the development of novel targets for the prevention and treatment of neuropsychiatric disorders.


Comorbidity of Mental and Physical Disorders

Comorbidity of Mental and Physical Disorders
Author: N. Sartorius
Publisher: Karger Medical and Scientific Publishers
Total Pages: 202
Release: 2014-11-26
Genre: Medical
ISBN: 3318026042

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This publication presents evidence about the magnitude and severe consequences of comorbidity of mental and physical illnesses from a personal and societal perspective. Leading experts address the huge burden of co-morbidity to the affected individual as well as the public health aspects, the costs to society and interaction with factors stemming from the context of socioeconomic developments. The authors discuss the clinical challenge of managing cardiovascular illnesses, cancer, infectious diseases and other physical illness when they occur with a range of mental and behavioral disorders, including substance abuse, eating disorders and anxiety. Also covered are the organization of health services, the training of different categories of health personnel and the multidisciplinary engagement necessary to prevent and manage comorbidity effectively. The book is essential reading for general practitioners, internists, public health specialists, psychiatrists, cardiologists, oncologists, medical educationalists and other health care professionals.