Inflammation And Epilepsy PDF Download
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Author | : Damir Janigro |
Publisher | : Springer Nature |
Total Pages | : 242 |
Release | : 2021-05-18 |
Genre | : Medical |
ISBN | : 3030674037 |
Download Inflammation and Epilepsy: New Vistas Book in PDF, ePub and Kindle
This book provides comprehensive information, both for clinicians and scientists, on the basic mechanisms, clinical features, and therapeutic approaches to epilepsy as an inflammatory disease. Inflammation has been for many years considered as an etiologic player (and a therapeutic target) for a specific group of epilepsies. However, it turns out that this concept underestimated the impact of inflammation in seizure disorders. Many accepted therapies for non-inflammatory epilepsies act in part as an inflammatory drug. The CNS actively responds to acute immune challenges by altering body temperature, stimulating the HPA axis, as well as up- and down-regulating specific sympathetic pathways.
Author | : Isam Jaber Al-Zwaini |
Publisher | : BoD – Books on Demand |
Total Pages | : 221 |
Release | : 2019-11-13 |
Genre | : Medical |
ISBN | : 1789238676 |
Download Epilepsy Book in PDF, ePub and Kindle
Epilepsy is the most common neurological disorder globally, affecting approximately 50 million people of all ages. It is one of the oldest diseases described in literature from remote ancient civilizations 2000-3000 years ago. Despite its long history and wide spread, epilepsy is still surrounded by myth and prejudice, which can only be overcome with great difficulty. The term epilepsy is derived from the Greek verb epilambanein, which by itself means to be seized and to be overwhelmed by surprise or attack. Therefore, epilepsy is a condition of getting over, seized, or attacked. The twelve very interesting chapters of this book cover various aspects of epileptology from the history and milestones of epilepsy as a disease entity, to the most recent advances in understanding and diagnosing epilepsy.
Author | : Andrea Bernasconi |
Publisher | : Cambridge University Press |
Total Pages | : 263 |
Release | : 2019-01-10 |
Genre | : Medical |
ISBN | : 1107108357 |
Download Imaging Biomarkers in Epilepsy Book in PDF, ePub and Kindle
Assembles world-class expertise on clinical and molecular imaging-derived biomarkers, presenting neuroimaging in epilepsy in a broad neuroscientific context.
Author | : Simon Shorvon |
Publisher | : Cambridge University Press |
Total Pages | : 1013 |
Release | : 2019-05-02 |
Genre | : Medical |
ISBN | : 1108420753 |
Download The Causes of Epilepsy Book in PDF, ePub and Kindle
Expanded and revised, this unique book provides concise descriptions of the many causes of epilepsy, for use in clinical practice.
Author | : Jianxiong Jiang |
Publisher | : Frontiers Media SA |
Total Pages | : 130 |
Release | : 2022-12-01 |
Genre | : Medical |
ISBN | : 2832508251 |
Download Neuroinflammation in Acquired Epilepsy Book in PDF, ePub and Kindle
Author | : Jacqueline A. Hubbard |
Publisher | : Academic Press |
Total Pages | : 395 |
Release | : 2016-07-05 |
Genre | : Medical |
ISBN | : 0128026243 |
Download Astrocytes and Epilepsy Book in PDF, ePub and Kindle
Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become "medically refractory". Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects. Recent findings indicate a critical contribution of astrocytes, star-shaped glial cells in the brain, to neuronal and network excitability and seizure activity. Furthermore, many important cellular and molecular changes occur in astrocytes in epileptic tissue in both humans and animal models of epilepsy. The goal of Astrocytes and Epilepsy is to comprehensively review exciting findings linking changes in astrocytes to functional changes responsible for epilepsy for the first time in book format. These insights into astrocyte contribution to seizure susceptibility indicate that astrocytes may represent an important new therapeutic target in the control of epilepsy. Astrocytes and Epilepsy includes background explanatory text on astrocyte morphology and physiology, epilepsy models and syndromes, and evidence from both human tissue studies and animal models linking functional changes in astrocytes to epilepsy. Beautifully labelled diagrams are presented and relevant figures from the literature are reproduced to elucidate key findings and concepts in this rapidly emerging field. Astrocytes and Epilepsy is written for neuroscientists, epilepsy researchers, astrocyte investigators as well as neurologists and other specialists caring for patients with epilepsy. Presents the first comprehensive book to synthesize historical and recent research on astrocytes and epilepsy into one coherent volume Provides a great resource on the field of astrocyte biology and astrocyte-neuron interactions Details potential therapeutic targets, including chapters on gap junctions, water and potassium channels, glutamate and adenosine metabolism, and inflammation
Author | : Marco Mula |
Publisher | : Academic Press |
Total Pages | : 413 |
Release | : 2019-04-20 |
Genre | : Medical |
ISBN | : 0128148780 |
Download The Comorbidities of Epilepsy Book in PDF, ePub and Kindle
Epilepsy is one of most frequent neurological disorders affecting about 50 million people worldwide and 50% of them have at least another medical problem in comorbidity; sometimes this is a the cause of the epilepsy itself or it is due to shared neurobiological links between epilepsy and other medical conditions; other times it is a long-term consequence of the antiepileptic drug treatment. The Comorbidities of Epilepsy offers an up-to-date, comprehensive overview of all comorbidities of epilepsy (somatic, neurological and behavioral), by international authorities in the field of clinical epileptology, with an emphasis on epidemiology, pathophysiology, diagnosis and management. This book includes also a critical appraisal of the methodological aspects and limitations of current research on this field. Pharmacological issues in the management of comorbidities are discussed, providing information on drug dosages, side effects and interactions, in order to enable the reader to manage these patients safely. The Comorbidities of Epilepsy is aimed at all health professionals dealing with people with epilepsy including neurologists, epileptologists, psychiatrists, clinical psychologists, epilepsy specialist nurses and clinical researchers. Provides a comprehensive overview of somatic, neurological and behavioral co-morbidities of epilepsy Discusses up-to-date management of comorbidities of epilepsy Written by a group of international experts in the field
Author | : G.A. Higgs |
Publisher | : Springer |
Total Pages | : 248 |
Release | : 1985-06-18 |
Genre | : Medical |
ISBN | : 1349078344 |
Download Inflammatory Mediators Book in PDF, ePub and Kindle
Author | : Harry Chugani, MD |
Publisher | : Oxford University Press |
Total Pages | : |
Release | : 2010-11-23 |
Genre | : Medical |
ISBN | : 0199711526 |
Download Neuroimaging in Epilepsy Book in PDF, ePub and Kindle
Perhaps the most important achievements in the field of epileptology in the past two decades have been in the neuroimaging and genetic breakthroughs as applied to patients with epilepsy. Indeed, neuroimaging has become a vital part in the study of epilepsy, affecting broad aspects of the disorder ranging from diagnosis and classification to treatment and prognosis. Neuroimaging in epilepsy encompasses many different approaches that have reached various levels of expertise across epilepsy centers worldwide. This book discusses every imaging modality used to gather information on epilepsy. Each technique is described by world experts and epilepsy centers worldwide.
Author | : Jerome Engel Jr |
Publisher | : Oxford University Press |
Total Pages | : 737 |
Release | : 2013-01-31 |
Genre | : Medical |
ISBN | : 019532854X |
Download Seizures and Epilepsy Book in PDF, ePub and Kindle
This second edition of 'Seizures and Epilepsy' is completely revised, due to tremendous advances in the understanding of the fundamental neuronal mechanisms underlying epileptic phenomena, as well as current diagnosis and treatment, which have been heavily influenced over the past several decades by seminal neuroscientific developments, particularly the introduction of molecular neurobiology, genetics, and modern neuroimaging. This resource covers a broad range of both basic and clinical epileptology.