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Infant Gut Microbiota Colonization and Food Impact

Infant Gut Microbiota Colonization and Food Impact
Author: Christophe Lacroix
Publisher: Frontiers Media SA
Total Pages: 184
Release: 2019-05-23
Genre:
ISBN: 2889458687

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.


Pediatric Nutrition in Practice

Pediatric Nutrition in Practice
Author: B. Koletzko
Publisher: Karger Medical and Scientific Publishers
Total Pages: 349
Release: 2015-04-17
Genre: Medical
ISBN: 3318026913

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There is no other time in life when the provision of adequate and balanced nutrition is of greater importance than during infancy and childhood. During this dynamic phase characterized by rapid growth, development and developmental plasticity, a sufficient amount and appropriate composition of nutrients both in health and disease are of key importance for growth, functional outcomes such as cognition and immune response, and the metabolic programming of long-term health and well-being. This compact reference text provides concise information to readers who seek quick guidance on practical issues in the nutrition of infants, children and adolescents. After the success of the first edition, which sold more than 50'000 copies in several languages, the editors prepared this thoroughly revised and updated second edition which focuses again on nutritional challenges in both affluent and poor populations around the world. Serving as a practical reference guide, this book will contribute to further improving the quality of feeding of healthy infants and children, as well as enhancing the standards of nutritional care in sick children.


How Fermented Foods Feed a Healthy Gut Microbiota

How Fermented Foods Feed a Healthy Gut Microbiota
Author: M. Andrea Azcarate-Peril
Publisher: Springer Nature
Total Pages: 367
Release: 2019-11-28
Genre: Technology & Engineering
ISBN: 3030287378

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This book examines the role of fermented foods on human gut health and offers a unique contribution to this rapidly growing area of study. Fermented foods have been consumed by humans for millennia. This method of food preservation provided early humans with beneficial bacteria that re-populated the gut microbiota upon consumption. However, novel methods of production and conservation of food have led to severed ties between the food that modern humans consume and the gut microbiota. As a consequence, there has been a documented increase in the prevalence of autoimmune diseases and obesity, which has been correlated to decreased diversity of gut microbes, while infectious disorders have decreased in the three past decades. With the intention of providing a thorough overview of the relationship between fermented foods, nutrition, and health, the editors have grouped the chapters into three thematic sections: food and their associated microbes, the oral microbiome, and the gut microbiome. After an introduction dedicated to the environmental microbiome, Part I provides an overview of what is currently known about the microbes associated with different foods, and compares traditional forms of food preparation with current industrial techniques in terms of the potential loss of microbial diversity. The chapters in Part 2 explore the oral microbiota as a microbial gatekeeper and main contributor to the gut microbiota. Part 3 introduces beneficial modulators of the gut microbiome starting with the establishment of a healthy gut microbiota during infancy, and continuing with the role of probiotics and prebiotics in health preservation and the imbalances of the gut microbiota. In the final section the editors offer concluding remarks and provide a view of the future brought by the microbiome research revolution. This study is unique in its emphasis on the convergence of two very relevant fields of research: the field of studies on Lactic Acid Bacteria (LAB) and fermented foods, and microbiome research. The relationship between these fields, as presented by the research in this volume, demonstrates the intimate connection between fermented foods, the oral and gut microbiota, and human health. Although research has been done on the impact of diet on the gut microbiome there are no publications addressing the restorative role of food as microbe provider to the gut microbiota. This novel approach makes the edited volume a key resource for scientific researchers working in this field.


Gut Microbiome and Its Impact on Health and Diseases

Gut Microbiome and Its Impact on Health and Diseases
Author: Debabrata Biswas
Publisher: Springer Nature
Total Pages: 288
Release: 2020-08-27
Genre: Technology & Engineering
ISBN: 3030473848

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This book provides a comprehensive examination of the role of gut microbiome/microflora in nutrition, metabolism, disease prevention and health issues, including farm animal health and food value, and human gastrointestinal health and immunity. Indigenous microbiotas, particularly the gut microflora/microbiome, are an essential component in the modern concept of human and animal health. The diet and lifestyle of the host and environment have direct impact on gut microflora and the patterns of gut microbial colonization associated with health and diseases have been documented. Contributing authors cover the impact of gut microbiome in farm animal health, and explore the possibility of modulating the human gut microbiome with better animal products to prevent human diseases, including endemic and emerging diseases such as obesity, cancer and cardiac diseases. Dieting plan and control methods are examined, with attention paid to balance dieting with natural food and drink components. In addition, the role of gut microbiota in enteric microbial colonization and infections in farm animals is also discussed. The volume also explores the possibility of improving human health by modulating the microbiome with better food, including bio-active foods and appropriate forms of intake. Throughout the chapters, authors examine cutting edge research and technology, as well as future directions for better practices regarding emerging issues, such as the safety and production of organic food.


The Human Microbiome, Diet, and Health

The Human Microbiome, Diet, and Health
Author: Food Forum
Publisher: National Academies Press
Total Pages: 197
Release: 2013-02-27
Genre: Medical
ISBN: 030926586X

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The Food Forum convened a public workshop on February 22-23, 2012, to explore current and emerging knowledge of the human microbiome, its role in human health, its interaction with the diet, and the translation of new research findings into tools and products that improve the nutritional quality of the food supply. The Human Microbiome, Diet, and Health: Workshop Summary summarizes the presentations and discussions that took place during the workshop. Over the two day workshop, several themes covered included: The microbiome is integral to human physiology, health, and disease. The microbiome is arguably the most intimate connection that humans have with their external environment, mostly through diet. Given the emerging nature of research on the microbiome, some important methodology issues might still have to be resolved with respect to undersampling and a lack of causal and mechanistic studies. Dietary interventions intended to have an impact on host biology via their impact on the microbiome are being developed, and the market for these products is seeing tremendous success. However, the current regulatory framework poses challenges to industry interest and investment.


Maternal Microbial Contributions and Ontogenesis of the Infant Microbiome in Health and Behavior

Maternal Microbial Contributions and Ontogenesis of the Infant Microbiome in Health and Behavior
Author: Danielle Nicole Rendina
Publisher:
Total Pages: 203
Release: 2019
Genre:
ISBN:

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Over the last decade, myriad scientific discoveries have highlighted the essential role of the gut microbiota during infancy for normal development, including for nutrient extraction and metabolism, maturation of immune competence and neurobehavioral phenotypes. Microbes begin colonizing the gastrointestinal tract rapidly during vaginal delivery and acquisition continues postpartum through exposure to microbes derived from the mother, breastmilk, and the rearing environment. This dissertation utilizes a rhesus monkey ([Macaca mulatta]) model and recent advancements in gene sequencing to gain further insights into the evolved expectation for early exposure to microbes, aiming to elucidate the salience of maternal contributions to the infant's gut microbiome and to improve our understanding of the bidirectional signaling pathways in the gut-brain axis. Through a descriptive examination of the trajectory of microbiota across infancy, we first establish that the bacterial community structure of the infant gut is dynamic, gradually becoming more diverse, with the maturation of microbial community structure influenced by the transition from breastmilk to solid foods. After characterizing the normative patterns of microbial succession, an observational study explored how the maturation of gut microbiota was influenced by maternal care, and was associated with the infant's behavior, and neurodevelopment (as determined by neuroimaging). Commensal taxa were found to vary with consummatory behavior and infant activity levels, but only the variation in the abundance of [Faecalibacterium] was significantly associated with infant temperament and neurodevelopment. Delayed acquisition of microbial community evenness and richness had physiological consequences and was predictive of slower growth trajectories and decreased neural volume at 1 year. Lastly, the early rearing environment was manipulated to investigate the benefits of exposure to the mother and breast milk for gut colonization and infant health outcomes. Cesarean-delivered and formula-fed infants had delayed trajectories of bacterial colonization, which were characterized by lower abundances of commensal taxa and a greater susceptibility to [Campylobacter]-induced diarrheic symptoms. Collectively, these studies further characterized several critical windows of infant development during which the patterns of gut microbial acquisition can impact host physiology, behavioral and brain maturation, and consequently, may have important implications for understanding the role of microbes and a dysbiotic gut in neurodevelopmental disorders.


Protecting Infants through Human Milk

Protecting Infants through Human Milk
Author: Larry K. Pickering
Publisher: Springer Science & Business Media
Total Pages: 506
Release: 2013-06-29
Genre: Medical
ISBN: 1475742428

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Protecting Infants through Human Milk: Advancing the Scientific Evidence provides a forum in which basic scientists, clinicians, epidemiologists, and policy makers exchange the latest findings regarding the effects of human milk and breastfeeding on infant and maternal health, thereby fostering new and promising collaborations. This volume also integrates data from animal and in vitro laboratory studies with clinical and population studies to examine human milk production and composition, the mechanisms of infant protection and/or risk from human milk feeding, and proposed interventions related to infant feeding practices. Additionally, it stimulates critical evaluation of, and advances in, the scientific evidence base and research methods, and identifies the research priorities in various areas.


The Antibiotic Resistome

The Antibiotic Resistome
Author: Gerry Wright
Publisher: Wiley
Total Pages: 384
Release: 2016-08-22
Genre: Science
ISBN: 9781118376737

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Intestinal Microbiome: Functional Aspects in Health and Disease

Intestinal Microbiome: Functional Aspects in Health and Disease
Author: E. Isolauri
Publisher: Karger Medical and Scientific Publishers
Total Pages: 192
Release: 2017-03-27
Genre: Medical
ISBN: 3318060313

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The intestinal microbiome is especially important during the first thousand days of life. Exposure to microbes in utero significantly impacts fetal development, in part through epigenetic processes and in part through hormonal influences which cause a change in the mother's intestinal microbiome. The nature of delivery and perinatal antibiotic treatment, as well as diet (especially in the postpartum period), can also influence initial microbial colonization and the development of appropriate intestinal defense mechanisms. These, in turn, can affect the expression of allergy, autoimmune disease, and brain function, among other things, later in life. The first part of this publication focuses on the development of the human microbiome in utero and the importance of normal colonization of the newborn gut in immune development and disease prevention. The second section deals with the normal development of gut microbiota and with clinical conditions associated with dysbiosis. The final chapters cover various aspects of human milk evolution and oligosaccharides.


The Hologenome Concept: Human, Animal and Plant Microbiota

The Hologenome Concept: Human, Animal and Plant Microbiota
Author: Eugene Rosenberg
Publisher: Springer Science & Business Media
Total Pages: 187
Release: 2014-01-31
Genre: Science
ISBN: 3319042416

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Groundbreaking research over the last 10 years has given rise to the hologenome concept of evolution. This concept posits that the holobiont (host plus all of its associated microorganisms) and its hologenome (sum of the genetic information of the host and its symbiotic microorganisms), acting in concert, function as a unique biological entity and therefore as a level of selection in evolution. All animals and plants harbor abundant and diverse microbiota, including viruses. Often the amount of symbiotic microorganisms and their combined genetic information far exceed that of their host. The microbiota with its microbiome, together with the host genome, can be transmitted from one generation to the next and thus propagate the unique properties of the holobiont. The microbial symbionts and the host interact in a cooperative way that affects the health of the holobiont within its environment. Beneficial microbiota protects against pathogens, provides essential nutrients, catabolizes complex polysaccharides, renders harmful chemicals inert, and contributes to the performance of the immune system. In humans and animals, the microbiota also plays a role in behavior. The sum of these cooperative interactions characterizes the holobiont as a unique biological entity. Genetic variation in the hologenome can be brought about by changes in either the host genome or the microbial population genomes (microbiome). Evolution by cooperation can occur by amplifying existing microbes, gaining novel microbiota and by acquiring microbial and viral genes. Under environmental stress, the microbiome can change more rapidly and in response to more processes than the host organism alone and thus influences the evolution of the holobiont. Prebiotics, probiotics, synbiotics and phage therapy are discussed as applied aspects of the hologenome concept.