Immunotherapies Towards HIV Cure
| Author | : Carolina Garrido |
| Publisher | : Frontiers Media SA |
| Total Pages | : 153 |
| Release | : 2021-07-08 |
| Genre | : Science |
| ISBN | : 2889669815 |
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Immunotherapies Towards Hiv Cure PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Immunotherapies Towards Hiv Cure PDF full book. Access full book title Immunotherapies Towards Hiv Cure.
HIV and Cancer Immunotherapy: Similar Challenges and Converging Approaches
| Author | : Mirko Paiardini |
| Publisher | : Frontiers Media SA |
| Total Pages | : 157 |
| Release | : 2020-05-15 |
| Genre | : |
| ISBN | : 2889637166 |
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HIV Vaccines and Cure
| Author | : Linqi Zhang |
| Publisher | : Springer |
| Total Pages | : 318 |
| Release | : 2018-07-20 |
| Genre | : Medical |
| ISBN | : 981130484X |
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This book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate persistent HIV and the rational design of vaccines to induce protective immunity are covered. This book also discusses the challenges related to the design of clinical trials for testing the safety and efficacy of these innovative approaches. This book will provide a systematic overview and also discuss controversial issues for researchers in virology and immunology, as well as practicing physicians, and scientists in the pharmaceutical industry.
HIV-1 Latency
| Author | : Guido Silvestri |
| Publisher | : Springer |
| Total Pages | : 248 |
| Release | : 2018-10-11 |
| Genre | : Medical |
| ISBN | : 303002816X |
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This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.
Lymph Node T Cell Dynamics and Novel Strategies for HIV Cure
| Author | : Constantinos Petrovas |
| Publisher | : Frontiers Media SA |
| Total Pages | : 186 |
| Release | : 2019-02-11 |
| Genre | : |
| ISBN | : 2889457583 |
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Currently, more than 36 million people are infected with HIV. Although the introduction of highly active anti-retroviral therapy (HAART) has led to substantial advances in the clinical management of HIV infected individuals, HAART cannot completely eliminate the virus. This is because CD4 T helper cells, harboring the virus, remain dormant reservoirs. These reservoirs are difficult to measure and are present even in HAART-treated HIV infected individuals with undetectable levels of HIV in the blood. A growing body of studies has revealed follicular helper (Tfh) CD4 T cells, a highly differentiated CD4 T cell population localized in immunologically sanctuary sites (follicle/germinal center), as a major reservoir of HIV. The present Frontiers in Immunology eBook compiles 16 timely review articles focusing on the dynamics of major follicular immune cell types in HIV/SIV infection and their potential role for disease pathogenesis and the viral persistence in the lymph node. This eBook provides a comprehensive presentation of recent published work on lymph node and especially Tfh cell dynamics in HIV infection and we hope that it will be useful for our further understanding of how such dynamics affect the interplay between virus and host as well as for the discovery of novel therapeutic targets in the fight against HIV.
Immunotreatment and Gene Therapy of HIV Infection
| Author | : Ulrich R. Hengge |
| Publisher | : |
| Total Pages | : 144 |
| Release | : 2004 |
| Genre | : |
| ISBN | : 9783895997020 |
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Tremendous progress in the understanding of the immune pathogenesis of HIV disease has been made in the last two decades like in no other field of science ever before. Besides the inhibition of viral replication with highly active antiretroviral therapy (HAART) immunoreconstitution remains an important mainstay to be achieved in the battle against HIV. Intensive research has led to worldwide phase-III studies of immunotreatment of HIV infection such as the SILCAAT and ESPRIT trials to boost existing immune responses and to restore the immune system leading to the control of viral replication. The science and practical management of immunotherapy of HIV patients is described by famous experts from immunology, virology, gene therapy, dermatology, and clinical medicine.
Hiv/AIDS
| Author | : Kayleigh Lee |
| Publisher | : Independently Published |
| Total Pages | : 0 |
| Release | : 2024-01-30 |
| Genre | : Health & Fitness |
| ISBN | : |
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Struggling with the daily grind of HIV treatment and care? Feeling overwhelmed trying to make sense of the dizzying array of emerging science around finding a cure? You're not alone. That's why I wrote this helpful guidebook demystifying all the latest advances toward better therapies and maybe even one day ending HIV for good. Inside, you'll find a comprehensive yet readable overview of virtually every major branch of current HIV research translated clearly for non-scientists. I walk you step-by-step through exciting new approaches, like using gene editing technologies to snip out HIV from infected cells. Or powering up the immune system's natural defenses with custom-designed vaccines and supercharged cells. You'll discover promising new long-acting treatments on the horizon that may finally free patients from daily medication routines. And you'll learn how scientists creatively combine multiple cutting-edge platforms to help control the virus. Along the way, my goal is to educate and inspire fresh hope by revealing all the remarkable innovation emerging from labs worldwide. I peel back the curtain so you can appreciate the intricate coordination evolving across diverse fields - from immunotherapy to nanomedicine to curative stem cell transplantation. Whether you're newly diagnosed or an HIV health advocate, this guide aims to be a trusted knowledge base answering your questions and a reassuring companion rekindling motivation during the toughest moments. Because knowing the brightest scientific minds wake up working to improve our futures every day is reason enough not to lose hope. The journey is long but progress continues.
Hacking the Immune System to Cure HIV-1
| Author | : Ariola Bardhi |
| Publisher | : |
| Total Pages | : 420 |
| Release | : 2018 |
| Genre | : |
| ISBN | : |
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Disease Control Priorities, Third Edition (Volume 6)
| Author | : King K. Holmes |
| Publisher | : World Bank Publications |
| Total Pages | : 506 |
| Release | : 2017-11-06 |
| Genre | : Medical |
| ISBN | : 1464805253 |
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Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Models of Protection Against HIV/SIV
| Author | : Gianfranco Pancino |
| Publisher | : Academic Press |
| Total Pages | : 362 |
| Release | : 2011-12-02 |
| Genre | : Medical |
| ISBN | : 0123877156 |
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A successful vaccine for the prevention and/or immunotherapy against HIV/AIDS is one of the prominent challenges of the 21st century. To date, all human vaccine trials against this virus/disease have resulted in failure, or at best have shown very low efficacy. The scientific community dealing with HIV/AIDS has unanimously proposed a focus on basic science, with the intention of identifying correlates of protection that can serve as guides in developing and evaluating vaccine preparation. However, Nature seems to have already found several ways of dealing with infections by HIV and related primate lentiviruses, either by resisting infection or, once infected, avoiding immune damage and immunodeficiency. Models of Protection Against HIV/SIV will allow for an in-depth reflection on the perspectives for vaccine and therapy research derived from important recent studies. It will be authored by some of the most well known specialists in the field of HIV resistance/protection: including F. Barré-Sinoussi (2008 Nobel Prize for Medicine winner), B. Walker, S. Rowland-Jones, A. Telenti, M. Lederman and F. Plummer. This book is structured in a unique way, looking at three models of resistance/protection separately and then comparing the models against one another to provide its readership with a detailed examination of the research that is most predominant in the search for a vaccine. This structure presents the information in an easy-to-understand format and gives the book a cross-discipline appeal -- an important reference for those in the scientific community, medical care, public health and academia alike. Provides extensive descriptions and comparisons on the different models of protection agains HIV/AIDS Comprehensive writing and illustrations Contributors are among the most eminent specialists in the field
