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Immunotherapy

Immunotherapy
Author: Aung Naing
Publisher: Springer Nature
Total Pages: 445
Release: 2022-01-01
Genre: Medical
ISBN: 3030793087

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The field of immuno-oncology continues to rapidly evolve as new insights to fight and treat cancer emerge. The fourth edition of Immunotherapy provides the most current overview of immuno-oncology in different cancer types and toxicities associated with immunotherapy. While immunotherapy has revolutionized the treatment landscape of several solid malignancies, several challenges still exist. Only a subset of patients derive clinical benefits; some do not respond at all, and others respond initially, only for their disease to progress later. Because these drugs can activate a broad range of immune cells, patients suffer from a unique set of side effects known as immune-related adverse events. As more immunotherapeutic agents are used in the clinic, it is important to provide updates about current and ongoing developments in the field to further research efforts and inform treatment decisions. The fourth edition will have a new focus on strategies to overcome the challenges associated with immunotherapy. Chapters will discuss topics such as biomarkers of response, resistance mechanisms, role of imaging in predicting immune-related adverse events, and management of immune-related adverse events. Written by leading experts conducting cutting-edge research, readers will gain up-to-date knowledge on the current state and future of immunotherapy.


Immunotherapeutics

Immunotherapeutics
Author: Rossen Donev
Publisher: Academic Press
Total Pages: 494
Release: 2022-03-17
Genre: Science
ISBN: 0323992285

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Immunotherapeutics, Volume 129 in the Advances in Protein Chemistry and Structural Biology series highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Vaccines for the prophylaxis and treatment of HPV, Lung-targeted RNA-based therapeutics, Clostridium difficile: Current overview and future perspectives, Antivenoms for treatment of snake bites, Natural killer cell-based strategies for immunotherapy of cancer, Immunological insights of selectins in human disease mechanism, Current update, challenges, and future aspects of immunotherapeutics in non-small cell lung cancer, In silico interaction analysis of NEMO binding domain peptide on the NFkB protein, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Advances in Protein Chemistry and Structural Biology series Updated release includes the latest information on Immunotherapeutics


Immunotherapy – A Novel Facet of Modern Therapeutics

Immunotherapy – A Novel Facet of Modern Therapeutics
Author: Sujata P. Sawarkar
Publisher: Springer Nature
Total Pages: 267
Release: 2020-12-16
Genre: Medical
ISBN: 9811590389

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This book illustrates the significance and relevance of immunotherapy in modern-day therapeutics. Focusing on the application of immunotherapy in oncology, neurodegenerative and autoimmune diseases, it discusses the drug delivery systems, and pre-clinical and clinical methodologies for immunotherapy-based drugs. It also comprehensively reviews various aspects of immunotherapy, such as regulatory affairs, quality control, safety, and pharmacovigilance. Further, the book discusses the in vitro validation of therapeutic strategies prior to patient application and management of immunotherapy-related side effects and presents case studies demonstrating the design and development (pre-clinical to clinical) of immunotherapy for various diseases. It also describes various design considerations and the scale-up synthesis of immunotherapeutics and screening methods. Lastly, it explores the important aspect of cost-effectiveness and rational immunotherapy strategies.


The Basics of Cancer Immunotherapy

The Basics of Cancer Immunotherapy
Author: Haidong Dong
Publisher: Springer Nature
Total Pages: 228
Release:
Genre:
ISBN: 3031594754

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Cancer Immunology and Immunotherapy

Cancer Immunology and Immunotherapy
Author: Mansoor M. Amiji
Publisher: Elsevier
Total Pages: 548
Release: 2021-08-27
Genre: Business & Economics
ISBN: 0128233974

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Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. Nanotechnology-based targeted delivery strategies could improve the delivery efficiency of IO agents as well as provide additional avenues for novel therapeutic and vaccination strategies. Additionally, a number of locally-administered immunogenic scaffolds and therapeutic strategies, such as the use of STING agonist, could benefit from rationally designed biomaterials and delivery approaches. Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side. Comprehensive treaty covering all aspects of immuno-oncology (IO) Novel strategies for delivery of IO therapeutics and vaccines Forecasting on the future of nanotechnology and drug delivery for IO


Translational Immunotherapy of Brain Tumors

Translational Immunotherapy of Brain Tumors
Author: John H. Sampson
Publisher: Academic Press
Total Pages: 406
Release: 2017-02-06
Genre: Science
ISBN: 0128026251

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Translational Immunotherapy of Brain Tumors gives researchers and practitioners an up-to-date and comprehensive overview of the field. Chapters include adoptive immunotherapy, immunosuppression, CAR therapy of brain tumors, and dendritic cell therapy for brain tumors. Very few agents have been shown to be efficacious in the treatment of malignant gliomas. Recently, there have been a number of studies demonstrating the potential success of immunotherapy for brain tumors. Immunotherapeutics are becoming the most frequent drugs to be used in cancer therapy. These new breakthroughs, now approved by the FDA, are a part of multiple phase III international trials and ongoing research in malignant glioma, meaning that the information in this cutting-edge book will be of great importance to practitioners and researchers alike. Comprehensive overview, providing an update on immunology, translational immunotherapy, and clinical trials relating to malignant gliomas Edited by a prominent neurosurgeon with contributions by leading researchers in the field Ideal resource for researchers and practitioners interested in learning about mechanisms that use the immune system to treat brain tumors


Concepts in Immunology and Immunotherapeutics

Concepts in Immunology and Immunotherapeutics
Author: Blaine T. Smith
Publisher: ASHP
Total Pages: 313
Release: 2008
Genre: Medical
ISBN: 1585281271

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Concepts in Immunology and Immunotherapeutics, 4th Edition provides a wide-ranging introduction to both basic and applied immunology.


Vaccines for Cancer Immunotherapy

Vaccines for Cancer Immunotherapy
Author: Nima Rezaei
Publisher: Academic Press
Total Pages: 198
Release: 2018-10-17
Genre: Medical
ISBN: 0128140402

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Therapeutic cancer vaccines represent a type of active cancer immunotherapy. Clinicians, scientists, and researchers working on cancer treatment require evidence-based and up-to-date resources relating to therapeutic cancer vaccines. Vaccines for Cancer Immunotherapy provides a reference for cancer treatment for clinicians and presents a well-organized resource for determining high-potential research areas. The book considers that this promising modality can be made more feasible as a treatment for cancer. Chapters cover cancer immunology, general approaches to cancer immunotherapy, vaccines, tumor antigens, the strategy of allogeneic and autologous cancer vaccines, personalized vaccines, whole-tumor antigen vaccines, protein and peptide vaccines, dendritic cell vaccines, genetic vaccines, candidate cancers for vaccination, obstacles to developing therapeutic cancer vaccines, combination therapy, future perspectives and concluding remarks on therapeutic cancer vaccines. Introduces the feasible immunotherapeutic vaccines for patients with different types of cancer Presents the status of past and current vaccines for cancer treatment Considers advantages and disadvantages of different therapeutic cancer vaccines Looks at the combination of vaccines and other modalities, including immunotherapeutic and conventional methods Analyzes obstacles to development of therapeutic cancer vaccines Gives a view on future perspectives in the application of therapeutic cancer vaccines


ImmunoTherapeutics: Market Overview

ImmunoTherapeutics: Market Overview
Author: Stephen Smith
Publisher: Xlibris Corporation
Total Pages: 257
Release: 2011-03-25
Genre: Health & Fitness
ISBN: 1456849301

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This book provides a complete overview for the international market surrounding immunosuppressants and immunostimulants for the years 2009 - 2014. Information includes regulatory landscape, new product development outlook, fi nancial overview and etc.


Cancer Immunotherapy Principles and Practice

Cancer Immunotherapy Principles and Practice
Author: Lisa H. Butterfield
Publisher:
Total Pages: 0
Release: 2017
Genre: Cancer
ISBN: 9781620700976

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Part 1: Intratumoral Signatures Associated With Immune Responsiveness