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Immunoregulation in Health and Disease

Immunoregulation in Health and Disease
Author: Miodrag L. Lukic
Publisher: Academic Press
Total Pages: 489
Release: 1997-05-14
Genre: Medical
ISBN: 0080534570

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Immunoregulation in Health and Disease, edited by Lukic, Colic, Mostarica-Stojkovic and Cuperlovic is a multi-authored volume covering the field of Immunoregulation, and will be essential reading for all researchers working in Immunology. Each section includes at least 10 papers contributed by experts from around the World, and covers in detail the wealth of knowledge relating to immunoregulation, both in health and disease. This book will provide an invaluable overview of immune system behaviour. The book is divided into four sections: Regulatory, effectory, and accessory cells of the immune response Molecular and cellular immunoregulatory mechanisms Hypersensitivity and autoimmunity Host reactivity to graft, tumour and infection


Essential Aspects of Immunometabolism in Health and Disease

Essential Aspects of Immunometabolism in Health and Disease
Author: Niels Olsen Saraiva Camara
Publisher: Springer Nature
Total Pages: 285
Release: 2021-10-21
Genre: Medical
ISBN: 303086684X

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Immunometabolism has emerged as an intersectional crossroad between metabolism and immune response. Over the past decade, it has become clear that most - if not all - immune cell functions are not separated from cellular metabolism. Although seminal works have addressed the metabolic fate of immune cells during differentiation and function, the physiological status of a given tissue is also dependent on the cell metabolism. The dialogue between immune cells and their microenvironment can also modulate cellular metabolism, which can trigger the onset and progression of a multitude of inflammation-mediated diseases. Thus, uncovering the specific characteristics of the metabolism in different immune cells types and in different conditions, can shed light into the molecular mechanisms of disease and help develop new drugs and therapeutic strategies to treat immune diseases. The edited volume Essentials aspects of Immunometabolism will give the readers a broad view on how metabolic pathways can influence many types of immune cells during activation, differentiation and function, in health and disease. Of note, the structure of the book was created thinking not only on the experienced immunologist but also on undergraduate and graduate students, physicians, and all members of the scientific community interested in this exciting field of research.


Stress, Immune Function, and Health

Stress, Immune Function, and Health
Author: Bruce S. Rabin
Publisher: Wiley-Liss
Total Pages: 368
Release: 1999-03-05
Genre: Medical
ISBN:

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Written by a renowned figure in the field of immunology and compiling a wealth of scientific information, Stress, Immune Function, and Health: The Connection looks at the long-term effects of stress on human health from a psychoneuroimmunological approach. The recent changes in dietary modifications, clinical applications, and evolution in the field of immunology have created the need for a book which addresses the growing awareness of health benefits that can be achieved by buffering the effects of stress on the immune system. Emphasizing the importance of the interaction among the mind, the body, and physical health, this reference includes important developmental procedures that can be used to resist stress on the immune system. By examining components of the immune system, along with the effects of psychological stress and the capacity for hormonal response, author Bruce Rabin demonstrates, in a concise, accessible manner, the ability of an individual's immune system to alter susceptibility to immune-mediated diseases. In addition, the book examines several key issues in this rapidly expanding field, including: * Information and examples that illustrate how distinct areas of the brain that perceive the presence of a stressor are able to communicate with the cells of the immune system * The correlation between stress-related changes in health practices and stressor-induced risks of disease development * The effect on the immune system due to stress from an increased concentration of neuropeptides and hormones * Behaviors and beliefs that can reduce the harmful effects of stress on the immune system by interfering with the stress-responsive areas of the brain * The issue of stress during pregnancy and the early period of development on behaviors and immune functions in children An authoritative guide for all researchers and students in the fields of immunology, neuroscience, and psychology, Stress, Immune Function, and Health: The Connection is also an essential reference for physicians and nurses concerned with stress and immune-related diseases.


Immunoregulation

Immunoregulation
Author: Nicola Fabris
Publisher: Springer Science & Business Media
Total Pages: 473
Release: 2012-12-06
Genre: Medical
ISBN: 1468445472

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Immunoregulation is one of the areas which has witnessed the most explosive advances of immunology during the past decade. It is in this area that the current view of the immune system has arisen and developed. There is indeed little doubt that immune reactions are primarily determined by messages which are genera ted within the immune system and passed among different types of immunologie cells. This cell communication not only determines the type, intensity and duration of the response after perturbation of the immune system by exogenous antigens, but it is also essential for preventing autoimmune reactions and their clinical conse quences. In order to assure aperfect balance within the enormous com plexity of the immune system, it is not surprising that multiple self-regulatory mechanisms are organized at different levels, such as antibody feedback, idiotypic-anti-idiotypic responses, suppres sor and helper T cells, lymphokine signals and genetic require ments. A nu mb er of observations in recent years have, however, demonstrated that consistent contributions to the immunological homeostasis are given also by signals generated outside of the immune system, namely,in the central and autonomous nervous system as weIl as in the endocrine apparatus. Furthermore, the interactions between the immune system and the other body homestatic mechanisms seem to be bidirectional: if immunological cells may be targets of neuroendocrinological factors, immunological products seem in turn to contribute to the neuro endocrine homeostasis.


Immunobiology

Immunobiology
Author: Charles Janeway
Publisher: Churchill Livingstone
Total Pages: 586
Release: 1997-01-01
Genre: Immune system
ISBN: 9780443059957

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Military Strategies for Sustainment of Nutrition and Immune Function in the Field

Military Strategies for Sustainment of Nutrition and Immune Function in the Field
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 722
Release: 1999-05-13
Genre: Medical
ISBN: 0309173183

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Every aspect of immune function and host defense is dependent upon a proper supply and balance of nutrients. Severe malnutrition can cause significant alteration in immune response, but even subclinical deficits may be associated with an impaired immune response, and an increased risk of infection. Infectious diseases have accounted for more off-duty days during major wars than combat wounds or nonbattle injuries. Combined stressors may reduce the normal ability of soldiers to resist pathogens, increase their susceptibility to biological warfare agents, and reduce the effectiveness of vaccines intended to protect them. There is also a concern with the inappropriate use of dietary supplements. This book, one of a series, examines the impact of various types of stressors and the role of specific dietary nutrients in maintaining immune function of military personnel in the field. It reviews the impact of compromised nutrition status on immune function; the interaction of health, exercise, and stress (both physical and psychological) in immune function; and the role of nutritional supplements and newer biotechnology methods reported to enhance immune function. The first part of the book contains the committee's workshop summary and evaluation of ongoing research by Army scientists on immune status in special forces troops, responses to the Army's questions, conclusions, and recommendations. The rest of the book contains papers contributed by workshop speakers, grouped under such broad topics as an introduction to what is known about immune function, the assessment of immune function, the effect of nutrition, and the relation between the many and varied stresses encountered by military personnel and their effect on health.


Potentiating Health and the Crisis of the Immune System

Potentiating Health and the Crisis of the Immune System
Author: S. Fulder
Publisher: Springer Science & Business Media
Total Pages: 289
Release: 2013-06-29
Genre: Medical
ISBN: 1489900594

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With all the enormous resources that are invested in medicine, it is sometimes a mystery why there is so much sickness still in evidence. Our life span, though higher than at any time in history, has now leveled off and has not significantly increased in the last two generations. There is a one-third increase in long-term illness in the last 20 years and a 44% increase in cancer incidence, which are not related to demographic issues. In some modern countries, the level of morbidity (defined as days off work because of sickness) has increased by two thirds in this time. Despite $1 trillion spent on cancer research in 20 years, the "War On Cancer" has recently been pronounced a complete failure by the u. s. President's Cancer Panel. Evidently we still have a long way to go. The goal of "Health for All by the Year 2000" as the World Health Organization has put it, is another forgotten dream. As ever, the answer will be found in breaking out of the old philosophical patterns and discovering the new, as yet unacceptable concepts. The problems of medicine today require a Kuhnian breakthrough into new paradigms, and new ways of thinking. And these new ways will not be mere variations of the old, but radical departures. This book, and the conference upon which it was based, is part of a search for these new pathways.


Immunomodulatory Functions of Nutritional Ingredients in Health and Disease

Immunomodulatory Functions of Nutritional Ingredients in Health and Disease
Author: Jia Sun
Publisher: Frontiers Media SA
Total Pages: 195
Release: 2019-04-09
Genre:
ISBN: 2889457966

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Nutritional immunology is a rapidly developing field. An expanding body of evidence demonstrates the impact of foods and nutritional components on gut and systemic immunity of consumers. During recent years, the implications of nutrition and nutritional intervention on prevention of disease have become accepted and has become an important tool in management of several diseases. Nutritional immunology might become even more important in the prevention of disease when the interplay between nutritional processes and immune system is better understood. Particularly, specific cellular and molecular immune responses provoked by nutrition and the role of the gut barrier and microbiota in the interplay needs more study. This content of eBook was designed to provide a timely collection on mechanistic, translational and clinical research on the interplay between foods, nutritional components and immunity in physiological and pathophysiological conditions.