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Image-Guided High-Precision Radiotherapy

Image-Guided High-Precision Radiotherapy
Author: Esther G. C. Troost
Publisher: Springer Nature
Total Pages: 314
Release: 2022-10-11
Genre: Medical
ISBN: 3031086015

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This book equips readers with detailed knowledge on the current status of image-guided radiotherapy with photons and particles and highlights issues that need to be addressed in order to further improve treatment outcomes. The opening chapters cover clinical and technical aspects of target volume definition using anatomic (computed tomography and magnetic resonance imaging; MRI) as well as functional (MRI and positron emission tomography) imaging. Up-to-date information is then provided on the full range of image-guided high-precision radiotherapy techniques, including IMRT/VMAT, stereotactic body radiation therapy, MR-guided linear accelerators, MR-guided brachytherapy, and particle therapy. The role of ultrasonography in image-guided radiotherapy is discussed, as are the available means for target volume demarcation and stabilization and adaptive radiation therapy. Finally, outcome evaluation is explored in depth, with a particular focus on the role of multimodality imaging in predicting tumor control and normal tissue toxicity. The authors are experts in different specialties and the book will be of high value for radiation oncologists, medical physicists, radiologists, nuclear medicine physicians, and radiation technicians.


Image-Guided Radiation Therapy

Image-Guided Radiation Therapy
Author: J. Daniel Bourland
Publisher: Taylor & Francis
Total Pages: 254
Release: 2012-02-22
Genre: Medical
ISBN: 1439802742

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Image-Guided Radiation Therapy presents key image-guided radiation treatment (IGRT) technologies for external beam radiotherapy. The book explores the decades-long technological developments that have occurred in the realm of image-guided conformal, customized radiation treatment. Expert authors, all of whom have actively participated in the develo


Image-Guided Stereotactic Radiosurgery

Image-Guided Stereotactic Radiosurgery
Author: Harun Badakhshi
Publisher: Springer
Total Pages: 263
Release: 2016-07-28
Genre: Medical
ISBN: 3319391895

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This book provides the reader with a detailed update on the use of stereotactic radiosurgery (SRS) in patients with lesions of the brain and other parts of the body. The aim is not simply to explain the application of SRS and document its value with reference to the author's own clinical experiences and other published evidence, but also to contextualize the technology within a new strategic concept of cancer care. When embedded within an appropriate conceptual framework, technology becomes pivotal in changing therapeutic strategies. A new paradigm that is increasingly impacting on clinical practice is the oligometastatic state, on the basis that long-term survival might be achieved in patients with a low volume and number of metastatic lesions. This book accordingly addresses the value of SRS in patients with oligometastases of solid tumors to the brain, lung, spine, and liver. In addition, it examines the use of SRS in patients with diverse brain lesions, early-stage stage lung cancer, liver cancer, and early-stage prostate cancer. Readers will be persuaded that SRS, using cutting-edge imaging technologies to deliver precisely targeted radiation therapy, represents an exciting non-invasive procedure that holds great promise for the present and the future of cancer care.


Adaptive Radiation Therapy

Adaptive Radiation Therapy
Author: X. Allen Li
Publisher: CRC Press
Total Pages: 404
Release: 2011-01-27
Genre: Medical
ISBN: 1439816352

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Modern medical imaging and radiation therapy technologies are so complex and computer driven that it is difficult for physicians and technologists to know exactly what is happening at the point-of-care. Medical physicists responsible for filling this gap in knowledge must stay abreast of the latest advances at the intersection of medical imaging an


Image-Guided Radiotherapy for Effective Radiotherapy Delivery

Image-Guided Radiotherapy for Effective Radiotherapy Delivery
Author: Nam Phong Nguyen
Publisher: Frontiers Media SA
Total Pages: 113
Release: 2016-04-22
Genre: Medicine (General)
ISBN: 2889198499

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Image-guided radiotherapy (IGRT) is a new radiotherapy technology that combines the rapid dose fall off associated with intensity-modulated radiotherapy (IMRT) and daily tumor imaging allowing for high precision tumor dose delivery and effective sparing of surrounding normal organs. The new radiation technology requires close collaboration between radiologists, nuclear medicine specialists, and radiation oncologists to avoid marginal miss. Modern diagnostic imaging such as positron emission tomography (PET) scans, positron emission tomography with Computed Tomograpgy (PET-CT), and magnetic resonance imaging (MRI) allows the radiation oncologist to target the positive tumor with high accuracy. As the tumor is well visualized during radiation treatment, the margins required to avoid geographic miss can be safely reduced , thus sparing the normal organs from excessive radiation. When the tumor is located close to critical radiosensitive structures such as the spinal cord, IGRT can deliver a high dose of radiation to the tumor and simultaneously decreasing treatment toxicity, thus potentially improving cure rates and patient quality of life. During radiotherapy, tumor shrinkage and changes of normal tissues/volumes can be detected daily with IGRT. The volume changes in the target volumes and organs at risk often lead to increased radiation dose to the normal tissues and if left uncorrected may result in late complications. Adaptive radiotherapy with re-planning during the course of radiotherapy is therefore another advantage of IGRT over the conventional radiotherapy techniques. This new technology of radiotherapy delivery provides the radiation oncologist an effective tool to improve patient quality of life. In the future, radiation dose-escalation to the residual tumor may potentially improve survival rates. Because the treatment complexity, a great deal of work is required from the dosimetry staff and physicists to ensure quality of care. Preliminary clinical results with IGRT are encouraging but more prospective studies should be performed in the future to assess the effectiveness of IGRT in improving patient quality of life and local control. In this Frontiers Research Topic, we encourage submission of original papers and reviews dealing with imaging for radiotherapy planning, the physics and dosimetry associated with IGRT, as well as the clinical outcomes for cancer treatment with IGRT for all tumor sites.


Image-Guided Radiation Therapy in Lymphoma Management

Image-Guided Radiation Therapy in Lymphoma Management
Author: Roger M. Macklis
Publisher: CRC Press
Total Pages: 96
Release: 2016-04-19
Genre: Medical
ISBN: 1420058754

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An ideal text for radiation oncologists, hematologist-oncologists, and radiologists, Image-Guided Radiotherapy and Functional Imaging in Modern Lymphoma Management is the foremost source for information on the increasingly important subject of image guided radiation therapy (IGRT) and its crucial role in the clinical evolution of high-precision ion


Image-Guided IMRT

Image-Guided IMRT
Author: Thomas Bortfeld
Publisher: Springer Science & Business Media
Total Pages: 452
Release: 2006-05-28
Genre: Medical
ISBN: 3540303561

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Intensity-modulated radiation therapy (IMRT), one of the most important developments in radiation oncology in the past 25 years, involves technology to deliver radiation to tumors in the right location, quantity and time. Unavoidable irradiation of surrounding normal tissues is distributed so as to preserve their function. The achievements and future directions in the field are grouped in the three sections of the book, each suitable for supporting a teaching course. Part 1 contains topical reviews of the basic principles of IMRT, part 2 describes advanced techniques such as image-guided and biologically based approaches, and part 3 focuses on investigation of IMRT to improve outcome at various cancer sites.


Image-Guided and Adaptive Radiation Therapy

Image-Guided and Adaptive Radiation Therapy
Author: Robert D. Timmerman
Publisher: Lippincott Williams & Wilkins
Total Pages: 384
Release: 2012-10-09
Genre: Medical
ISBN: 1469801876

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This book provides detailed, state-of-the-art information and guidelines on the latest developments, innovations, and clinical procedures in image-guided and adaptive radiation therapy. The first section discusses key methodological and technological issues in image-guided and adaptive radiation therapy, including use of implanted fiducial markers, management of respiratory motion, image-guided stereotactic radiosurgery and stereotactic body radiation therapy, three-dimensional conformal brachytherapy, target definition and localization, and PET/CT and biologically conformal radiation therapy. The second section provides practical clinical information on image-guided adaptive radiation therapy for cancers at all common anatomic sites and for pediatric cancers. The third section offers practical guidelines for establishing an effective image-guided adaptive radiation therapy program.


Clinical Radiation Oncology

Clinical Radiation Oncology
Author: Leonard L. Gunderson, MD, MS, FASTRO
Publisher: Elsevier Health Sciences
Total Pages: 2253
Release: 2015-08-26
Genre: Medical
ISBN: 0323240984

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Perfect for radiation oncology physicians and residents needing a multidisciplinary, treatment-focused resource, this updated edition continues to provide the latest knowledge in this consistently growing field. Not only will you broaden your understanding of the basic biology of disease processes, you'll also access updated treatment algorithms, information on techniques, and state-of-the-art modalities. The consistent and concise format provides just the right amount of information, making Clinical Radiation Oncology a welcome resource for use by the entire radiation oncology team. Content is templated and divided into three sections -- Scientific Foundations of Radiation Oncology, Techniques and Modalities, and Disease Sites - for quick access to information. Disease Sites chapters summarize the most important issues on the opening page and include a full-color format, liberal use of tables and figures, a closing section with a discussion of controversies and problems, and a treatment algorithm that reflects the treatment approach of the authors. Chapters have been edited for scientific accuracy, organization, format, and adequacy of outcome data (such as disease control, survival, and treatment tolerance). Allows you to examine the therapeutic management of specific disease sites based on single-modality and combined-modality approaches. Features an emphasis on providing workup and treatment algorithms for each major disease process, as well as the coverage of molecular biology and its relevance to individual diseases. Two new chapters provide an increased emphasis on stereotactic radiosurgery (SRS) and stereotactic body irradiation (SBRT). New Associate Editor, Dr. Andrea Ng, offers her unique perspectives to the Lymphoma and Hematologic Malignancies section. Key Points are summarized at the beginning of each disease-site chapter, mirroring the template headings and highlighting essential information and outcomes. Treatment algorithms and techniques, together with discussions of controversies and problems, reflect the treatment approaches employed by the authors. Disease Site Overviews allow each section editor to give a unique perspective on important issues, while online updates to Disease Site chapters ensure your knowledge is current. Disease Site chapters feature updated information on disease management and outcomes. Four videos accessible on Expert Consult include Intraoperative Irradiation, Prostate Brachytherapy, Penile Brachytherapy, and Ocular Melanoma. Thirty all-new anatomy drawings increase your visual understanding. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.


Image-guided Radiation Therapy

Image-guided Radiation Therapy
Author: Arno J. Mundt
Publisher: PMPH-USA
Total Pages: 672
Release: 2010-12-31
Genre: Medical
ISBN: 9781607950424

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Image Guided Radiation Therapy (IGRT) is a true revolution in the field of radiation oncology. IGRT provides the unprecedented means of conforming does to the shape of the target tissues in 3-dimensions reducing the risk of complications thereby improving the quality of life of irradiated patients. Moreover, IGRT provides the means to deliver higher than conventional doses thus improving the chance of cure in these patients. Despite its established benefits, several barriers exist to the widespread clinical implementation of IGRT. In the past, great concerns existed regarding the large capital outlay needed for both software and hardware. This barrier is less relevant today given the increased reimbursements possible with IGRT. Today, the most significant barrier is education. IGRT is a fundamentally new approach to both treatment planning and delivery. Adoption of the IGRT approach entails new ways of thinking in regard to patient selection, treatment planning and quality assurance measures. Unfortunately, apart from a few University-based short courses, limited resources are available for the physician and physicist interested in learning IGRT.