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Hypofractionated and Stereotactic Radiation Therapy

Hypofractionated and Stereotactic Radiation Therapy
Author: Orit Kaidar-Person
Publisher: Springer
Total Pages: 404
Release: 2018-07-31
Genre: Medical
ISBN: 3319928023

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This handbook summarizes the data and techniques for hypofractionation and stereotactic radiation in a clinically-accessible way. Hypofractionated radiation therapy, which consists of larger-dose radiation treatments that are given over a shorter time period compared to conventional radiation fraction sizes, is used to treat a variety of cancers, including prostate, breast, lung, and colorectal. Conventional radiation therapy and hypofractionated radiation therapy have different effectiveness rates for cancer treatment and have different impacts on normal tissues in terms of causing toxicity. There is a significant and growing body of literature on the use of different dosing regimens to treat a variety of cancers and radiation oncologists need to keep up with the various dosing schedules, the effect of each regimen on cancer control in different cancers, and how the different schedules affect each organ in terms of toxicity. The book thus provides concise information ranging from commonly-used dose-fractionation schemes for hypofractionated and stereotactic body radiotherapy to simulation and treatment specifications to published safety and efficacy data. Chapters additionally examine the biological rationales for the efficacy of hypofractionated radiation; present clinical studies that demonstrate the efficacy and safety of hypofractionated radiation treatment in a variety of cancers; and describe the advances in technology that have allowed hypofractionated radiation to be safely given. This is an ideal guide for radiation oncology clinicians and trainees.


Image-Guided Hypofractionated Stereotactic Radiosurgery

Image-Guided Hypofractionated Stereotactic Radiosurgery
Author: Arjun Sahgal
Publisher: CRC Press
Total Pages: 617
Release: 2021-07-21
Genre: Medical
ISBN: 1000392236

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• Discusses the pros and cons of hypofractionated SRT compared to single-fraction radiosurgery, providing a deeper understanding of radiosurgery and radiobiology. • Explains the toxicity and adverse effects of hypofractionated SRT including the 24 Gy in 2 spine SBRT fractionation scheme, aiding practitioners in communicating the risks and benefits of treatment and in obtaining their patients’ consent. • Outlines the current standards for safe practice, including checklists for implementation. • Explores new technologies for brain and spine tumours including LITT, MR Guided Focussed Ultrasound and Zap technology with chapters authored by well-recognized experts in the radiation, oncology, and neurosurgery communities, this book delivers a level of technological and clinical detail not available in journal papers.


Stereotactic Body Radiation Therapy

Stereotactic Body Radiation Therapy
Author: Simon S. Lo
Publisher: Springer Science & Business Media
Total Pages: 433
Release: 2012-08-28
Genre: Medical
ISBN: 364225604X

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Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.


Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy

Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy
Author: Stanley H. Benedict
Publisher: CRC Press
Total Pages: 408
Release: 2014-08-01
Genre: Medical
ISBN: 1439841985

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Written by internationally known experts in the field, Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy examines one of the fastest-developing subspecialties within radiation oncology. These procedures deliver large doses of radiation in one to five sessions to a precisely determined target. Often these techniques have proven to be


Stereotactic Body Radiation Therapy

Stereotactic Body Radiation Therapy
Author: Brian D. Kavanagh
Publisher: Lippincott Williams & Wilkins
Total Pages: 186
Release: 2005
Genre: Medical
ISBN: 9780781754200

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"Kavanaugh (radiation oncology, University of Colorado Comprehensive Cancer Center) and Timmerman (image guided stereotactic radiation therapeutics, University of Texas Southwestern Medical Center) demonstrate the power of stereotactic body radiation therapy (SBRT) as a weapon in the cancer-fighting arsenal, and give advice on building a clinical SBRT program. Intended as a primer for radiation oncologists, physicists, radiobiologists, dosimetrists, and other members of the cancer team, and the book covers the radiobiology, physics, and dosimetry of SBRT, and gives practical details on procedures for specific conditions. B&w photos and medical images are included. Annotation: 2004 Book News, Inc., Portland, OR (booknews.com)"--[source inconnue].


Handbook of Evidence-Based Stereotactic Radiosurgery and Stereotactic Body Radiotherapy

Handbook of Evidence-Based Stereotactic Radiosurgery and Stereotactic Body Radiotherapy
Author: Rajni A. Sethi
Publisher: Springer Nature
Total Pages: 303
Release: 2023-10-01
Genre: Medical
ISBN: 3031331567

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This handbook concisely summarizes state-of-the-art information about stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT), including the history and development of these modalities, the biologic rationale for these technologies, typical practices, and reported results. Developed as a companion to Handbook of Evidence-Based Radiation Oncology, edited by Eric Hansen and Mack Roach, III, it is organized by disease site and presents treatment techniques and recommended imaging; safety and quality assurance; toxicities and management; recommended follow-up; and supporting evidence. Inclusion of evidence-based guidelines is intended to help inform decisions regarding the appropriateness of SRS and SBRT and guide treatment and evaluation. This new edition is fully updated with the latest literature. A new chapter on dose constraints has also been added, along with additional content on SBRT for oligometastatic disease and prostate, and the integration of SBRT with systemic therapy, including chemotherapy, immunotherapy, targeted agents. Case examples are added, as well as additional images to highlight situations described. Handbook of Evidence-Based Stereotactic Radiosurgery and Stereotactic Body Radiotherapy, 2e can be easily referenced in the clinic and is a valuable guide for radiation oncology practitioners


Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy (SBRT)

Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy (SBRT)
Author: Dwight E. Heron, MD, MBA, FACRO, FACR
Publisher: Springer Publishing Company
Total Pages: 600
Release: 2018-09-28
Genre: Medical
ISBN: 0826168574

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Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy (SBRT) is a comprehensive guide for the practicing physician and medical physicist in the management of complex intracranial and extracranial disease. It is a state-of-the-science book presenting the scientific principles, clinical background and procedures, treatment planning, and treatment delivery of SRS and SBRT for the treatment of tumors throughout the body. This unique textbook is enhanced with supplemental video tutorials inclusive to the resource. Beginning with an overview of SRS and SBRT, Part I contains insightful coverage on topics such as the evolving radiobiological principles that govern treatment, imaging, the treatment planning process, technologies and equipment used, as well as focused chapters on quality assurance, quality management, and patient safety. Part II contains the clinical application of SRS and SBRT for tumors throughout the body including those in the brain, head and neck, lung, pancreas, adrenal glands, liver, prostate, cervix, spine, and in oligometastatic disease. Each clinical chapter includes an introduction to the disease site, followed by a thorough review of all indications and exclusion criteria, in addition to the important considerations for patient selection, treatment planning and delivery, and outcome evaluation. These chapters conclude with a detailed and site-specific dose constraints table for critical structures and their suggested dose limits. International experts on the science and clinical applications of these treatments have joined together to assemble this must-have book for clinicians, physicists, and other radiation therapy practitioners. It provides a team-based approach to SRS and SBRT coupled with case-based video tutorials in disease management, making this a unique companion for the busy radiosurgical team. Key Features: Highlights the principles of radiobiology and radiation physics underlying SRS and SBRT Presents and discusses the expected patient outcomes for each indicated disease site and condition including a detailed analysis of Quality of Life (QOL) and Survival Includes information about technologies used for the treatment of SRS and SBRT Richly illustrated with over 110 color images of the equipment, process flow diagrams and procedures, treatment planning techniques and dose distributions 7 high-quality videos reviewing anatomy, staging, treatment simulation and planning, contouring, and management pearls Dose constraint tables at the end of each clinical chapter listing critical structures and their appropriate dose limits Includes access to the fully-searchable downloadable eBook


Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy

Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy
Author: Daniel M. Trifiletti
Publisher: Springer
Total Pages: 435
Release: 2019-06-27
Genre: Medical
ISBN: 3030169243

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This book is a comprehensive review of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT): its physics, clinical evidence, indications, and future directions. The utilization of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) is increasing internationally because of several factors. First, it offers patients a local treatment option that has demonstrated effectiveness similar to traditional surgery without the morbidity of general anesthesia and open surgical resection. Second, recent advancements in the quality of scientific evidence supporting a SRS or SBRT-containing approach in patients continues to evolve and demonstrate favorable disease-specific outcomes with little, if any, toxicity in various anatomic disease sites and for various conditions including cancer, benign tumors, and other psychiatric and neurologic conditions. Third, and most provocatively, is the notion that definitive local therapy (i.e. SRS or SBRT) in patients with cancer can boost the immune system to fight cancer in other sites throughout the body. While traditional medical knowledge would suggest that all patients with metastatic cancer are incurable, there is a mounting body of evidence that there is a subset of these patients that can be cured with definitive SRS or SBRT. This volume thus delves into each of these benefits and aspects of treatment, guiding physicians to the best treatment plan for their patients. Expert, international authors provide guidelines for SRS and SBRT use by clinicians. Chapters are divided into six main sections: Radiobiology of Radiosurgery and Stereotactic Body Radiation Therapy, Intracranial Radiosurgery Technique, Intracranial Radiosurgery by Indication, Stereotactic Body Radiation Therapy Technique, Stereotactic Body Radiation Therapy by Indication, The Future of Radiosurgery and SBRT. Overall physics are explained, as well as specific considerations for particular surgical tools (including the Leksell Gamma Knife and Accuray CyberKnife), techniques (including fractionated and charged particle radiosurgery), and anatomic sites (including brain metastases, pituitary tumors, and the prostate). Detailed images and charts enhance the chapters. This book provides physicians with a single, practical resource incorporating both of these broad categories of treatment, SRS and SBRT, and better defines the current role and the direction of radiosurgery.


Stereotactic Body Radiation Therapy

Stereotactic Body Radiation Therapy
Author: Yasushi Nagata
Publisher: Springer
Total Pages: 246
Release: 2015-08-06
Genre: Medical
ISBN: 4431548831

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This book serves as a practical guide for the use of stereotactic body radiation therapy in clinics. On the basis of more than 10 years of clinical experience with lung cancer, liver cancer and other cancers, a remarkable volume of knowledge has been accumulated. At the same time, great progress in techniques has been achieved. Various new fixing apparatuses, new respiratory regulation techniques, new dose fractionation schedules and new image-guided radiation therapy machines have been developed. This book reviews the history of those developments and reports on various types of toxicities. Review of recent clinical studies is also included. The authors were key members of the JCOG 0403 clinical trials on stereotactic body radiation therapy (SBRT) for both inoperable and operableT1N0M0 primary lung cancer. Readers will learn of the superior outcomes obtained with SBRT for lung cancer and other cancers in terms of local control and toxicities. With its practical focus, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists and senior nurses as well as medical oncologists and surgical oncologists who are interested in radiotherapy.


Stereotactic Body Radiotherapy

Stereotactic Body Radiotherapy
Author: Andrew Gaya
Publisher: Springer
Total Pages: 336
Release: 2015-01-24
Genre: Medical
ISBN: 0857295977

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This is a single, comprehensive handbook for clinical oncology trainees and consultants, covering the basic aspects of stereotactic radiotherapy systems and treatment.