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Hydrogels and Nanogels - Applications in Medicine

Hydrogels and Nanogels - Applications in Medicine
Author: Chukwuebuka Umeyor
Publisher: BoD – Books on Demand
Total Pages: 188
Release: 2024-01-31
Genre: Technology & Engineering
ISBN: 1837697930

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This book provides an overview of hydrogels and nanogels, including their manufacturing techniques, physicochemical and mechanical properties, and applications in medicine, as well as bioengineering strategies and their impacts on the functions of carrier systems. It explores the fundamentals of the synthesis, synthetic chemistry, and development of hydrogels and nanogels. It discusses the fabrication of stimuli-responsive hydrogels and nanogels and biomaterial requirements, as well as reviews the various classifications of hydrogels and nanogels and their self-assembly and gelation mechanisms. The book also highlights the mechanisms of drug encapsulation and release from hydrogels and nanogels and their biocompatibility with physiological membranes. Furthermore, it provides information on how to modify or engineer the surface of biomimetic systems for targeting purposes and the materials to be used to realize this objective. The book discusses factors to consider for the clinical translation of hydrogels and nanogels. Finally, it discusses the biomedical applications of hydrogels and nanogels, including in drug delivery, wound healing, and neurological and ophthalmic diseases.


Biomedical Applications of Hydrogels Handbook

Biomedical Applications of Hydrogels Handbook
Author: Raphael M. Ottenbrite
Publisher: Springer Science & Business Media
Total Pages: 438
Release: 2010-09-05
Genre: Technology & Engineering
ISBN: 144195919X

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Hydrogels are networks of polymer chains which can produce a colloidal gel containing over 99 per cent water. The superabsorbency and permeability of naturally occurring and synthetic hydrogels give this class of materials an amazing array of uses. These uses range from wound dressings and skin grafts to oxygen-permeable contact lenses to biodegradable delivery systems for drugs or pesticides and scaffolds for tissue engineering and regenerative medicine. Biomedical Applications of Hydrogels Handbook provides a comprehensive description of this diverse class of materials, covering both synthesis and properties and a broad range of research and commercial applications. The Handbook is divided into four sections: Stimuli-Sensitive Hydrogels, Hydrogels for Drug Delivery, Hydrogels for Tissue Engineering, and Hydrogels with Unique Properties. Key Features: Provides comprehensive coverage of the basic science and applications of a diverse class of materials Includes both naturally occurring and synthetic hydrogels Edited and written by world leaders in the field.


Nanogels for Biomedical Applications

Nanogels for Biomedical Applications
Author: Arti Vashist
Publisher: Royal Society of Chemistry
Total Pages: 322
Release: 2017-11-20
Genre: Medical
ISBN: 1782628622

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A comprehensive overview of nanogel-based systems and their applications in nanomedicine.


Nanogels for Biomedical Applications

Nanogels for Biomedical Applications
Author: Arti Vashist
Publisher: Royal Society of Chemistry
Total Pages: 322
Release: 2017-11-20
Genre: Science
ISBN: 1788012526

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Nanogel-based systems have gained tremendous attention due to their diverse range of applications in tissue engineering, regenerative medicine, biosensors, orthopaedics, wound healing and drug delivery. Nanogels for Biomedical Applications provides a comprehensive overview of nanogels and their use in nanomedicine. The book starts with the synthesis, methods and characterization techniques for nanogel-based smart materials followed by individual chapters demonstrating the different uses of the materials. Applications covered include anticancer therapy, tuberculosis diagnosis and treatment, tissue engineering, gene delivery and targeted drug delivery. The book will appeal to biologists, chemists, and nanotechnologists interested in translation research for personalized nanomedicine for health care.


Hydrogels

Hydrogels
Author: Thakur Raghu Raj Singh
Publisher: CRC Press
Total Pages: 289
Release: 2018-02-28
Genre: Medical
ISBN: 1351648276

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Hydrogels are crosslinked, macromolecular polymeric materials arranged in a three-dimensional network, which can absorb and retain large amounts of water. Hydrogels are commonly used in clinical practice and experimental medicine for a wide range of applications, including drug delivery, tissue engineering and regenerative medicine, diagnostics, cellular immobilization, separation of biomolecules or cells, and barrier materials to regulate biological adhesions. This book elucidates the underlying concepts and emerging applications of hydrogels and will provide key case studies and critical analysis of the existing research.


Tunable Hydrogels

Tunable Hydrogels
Author: Antonina Lavrentieva
Publisher: Springer Nature
Total Pages: 256
Release: 2021-05-31
Genre: Science
ISBN: 3030767698

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This book reviews the current knowledge on tunable hydrogels, including the range of different materials and applications, as well as the existing challenges and limitations in the field. It covers various aspects of the material design, particularly highlighting biological responsiveness, degradability and responsiveness to external stimuli. In this book, readers will discover original research data and state-of-the-art reviews in the area of hydrogel technology, with a specific focus on biotechnology and medicine. Written by leading experts, the contributions outline strategies for designing tunable hydrogels and offer a detailed evaluation of the physical and synthetic methods currently employed to achieve specific hydrogel properties and responsiveness. This highly informative book provides important theoretical and practical insights for scholars and researchers working with hydrogels for biomedical and biotechnological applications.


Nanocellulose and Nanohydrogel Matrices

Nanocellulose and Nanohydrogel Matrices
Author: Mohammad Jawaid
Publisher: John Wiley & Sons
Total Pages: 424
Release: 2017-05-09
Genre: Technology & Engineering
ISBN: 3527803858

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This first book on nanocellulose and nanohydrogels for biomedical applications is unique in discussing recent advancements in the field, resulting in a comprehensive, well-structured overview of nanocellulose and nanohydrogel materials based nanocomposites. The book covers different types of nanocellulose materials and their recent developments in the drug delivery and nanomedicine sector, along with synthesis, characterization, as well as applications in the biotechnological and biomedical fields. The book also covers the current status and future perspectives of bacterial cellulose and polyester hydrogel matrices, their preparation, characterization, and tissue engineering applications of water soluble hydrogel matrices obtained from biodegradable sources. In addition, the chitosan-based hydrogel and nanogel matrices, their involvement in the current biofabrication technologies, and influencing factors towards the biomedical sector of biosensors, biopharmaceuticals, tissue engineering appliances, implant materials, diagnostic probes and surgical aids are very well documented. Further, the history of cellulose-based and conducting polymer-based nanohydrogels, their classification, synthesis methods and applicability to different sectors, the challenges associated with their use, recent advances on the inhibitors of apoptosis proteins are also included. The recent developments and applications in the drug delivery sector gives an overview of facts about the nanofibrillated cellulose and copoly(amino acid) hydrogel matrices in the biotechnology and biomedicine field. This book serves as an essential reference for researchers and academics in chemistry, pharmacy, microbiology, materials science and biomedical engineering.


Hydrogel Micro and Nanoparticles

Hydrogel Micro and Nanoparticles
Author: L. Andrew Lyon
Publisher: John Wiley & Sons
Total Pages: 633
Release: 2012-09-24
Genre: Technology & Engineering
ISBN: 3527646442

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The book provides experienced as well as young researchers with a topical view of the vibrant field of soft nanotechnology. In addition to elucidating the underlying concepts and principles that drive continued innovation, major parts of each chapter are devoted to detailed discussions of potential and already realized applications of micro- and nanogel- based materials. Examples of the diverse areas impacted by these materials are biocompatible coatings for implants, films for controlled drug release, self-healing soft materials and responsive hydrogels that react to varying pH conditions, temperature or light.


Multifunctional Hydrogels

Multifunctional Hydrogels
Author: José García-Torres
Publisher: CRC Press
Total Pages: 413
Release: 2024-04-19
Genre: Technology & Engineering
ISBN: 1040009999

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Hydrogels are important polymer-based materials with innate fascinating properties and applications: they are three-dimensional, hydrophilic, polymeric networks that can absorb large amounts of water or aqueous fluids and are biocompatible, mechanically flexible, and soft. The incorporation of functionalities to develop smart and bioactive platforms has led to a myriad of applications. This book offers a comprehensive overview of multifunctional hydrogels, covering fundamentals, properties, and advanced applications in a progressive way. While each chapter can be read stand-alone, together they clearly describe the fundamental concepts of design, synthesis, and fabrication, as well as properties and performances of smart multifunctional hydrogels and their advanced applications in the biomedical, environmental, and robotics fields. This book: • Introduces readers to different hydrogel materials and the polymer types used to fabricate them. • Discusses conducting polymer hydrogels, nanocomposite hydrogels, and self-healing hydrogels. • Covers synthesis methodologies and fabrication techniques commonly used to confer certain structures and/or architectures. • Shows how hydrogels can be modified to incorporate new functionalities able to respond to physical and/or chemical changes. • Examines applications including bioelectronics, sensors and biosensors, tissue engineering, drug delivery, antipathogen applications, cancer theranostics, environmental applications, and soft robotics, with chapters showcasing the main advances achieved up to date in every field. Multifunctional Hydrogels: From Basic Concepts to Advanced Applications serves as a valuable resource for academic and industry researchers from interdisciplinary fields including materials science, chemistry, chemical engineering, bioengineering, physics, and pharmaceutical engineering.


Intelligent Hydrogels in Diagnostics and Therapeutics

Intelligent Hydrogels in Diagnostics and Therapeutics
Author: Anujit Ghosal
Publisher: CRC Press
Total Pages: 164
Release: 2020-05-27
Genre: Technology & Engineering
ISBN: 1000056147

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This book explores the potential of hydrogels as a multiutility system and their benefits (biocompatibility, degradability, and supporting scaffolds) for a wide range of applications in diagnostics and therapeutics. It also discusses the future prospects and challenges facing hydrogels. A wide variety of smart hydrogels (conducting, stimuli responsive, and others) with possible biomedical applications are elaborated. The book demonstrates the effectiveness of hydrogels in diagnostics of diseases in various in vivo and in vitro environments and highlights the engineering/functionalization of hydrogels for everyday drug dosage as an efficient drug carrier, scaffold, and sensing application. Explores the potential of hydrogels as a multifunctional system and their benefits, particularly for biomedical applications in diagnostics as well as therapeutics. Highlights the designing and engineering of hydrogels for everyday drug dosage and possible functionalization to fabricate an efficient drug carrier. Examines the significance of biopolymer-based hydrogels and their responsiveness in different physiological fluids. Demonstrates the effectiveness of hydrogels in diagnostics of diseases in various in,vivo and in,vitro environments. Presents challenges associated with the hydrogels and discusses possible in-hand modifications at length. Dr. Anujit Ghosal worked in the School of Biotechnology, Jawaharlal Nehru University, India. Currently, he is affiliated with the School of Life Sciences, Beijing Institute of Technology, Beijing, PRC. Dr. Ghosal researches in biochemistry, polymer chemistry, and nanotechnology. He has been the recipient of prestigious fellowships throughout his research career. His research ability is proven by his published peer-reviewed research and review articles and contributed book chapters. Dr. Ajeet Kaushik works as an assistant professor of chemistry and is exploring advanced electrochemical sensing systems and nanomedicine for personalized health wellness at the Department of Natural Sciences of the Division of Science, Arts, and Mathematics at Florida Polytechnic University, Lakeland, US. He is the recipient of various reputed awards for his service in the area of nanobiotechnology for health care. His excellent research credentials are reflected by his four edited books, 100 international research peer-reviewed publications, and three patents in the area of nanomedicine and smart biosensors for personalized health care.