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Human Trophoblast Neoplasms

Human Trophoblast Neoplasms
Author: Ronald A. Pattillo
Publisher: Springer Science & Business Media
Total Pages: 500
Release: 2013-03-13
Genre: Medical
ISBN: 1468448110

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This book addresses neoplasms of the human trophoblast. The scant literature available on the epidemiology of trophoblast neoplasms suggests that they are as much as ten times more common in Africa, Asia, India, and much of the developing world than in Western countries. The stimulus for the book evolved out of a common interest to combine Western technology with the clinical experience in the developing world in a common pursuit of the study and eradication of trophoblast neoplasia. There is substantial evidence to contend that gene derepression as seen in trophoblastic disease may be a universal prerequisite to neoplastic transformation in general. The recent discovery that the tumor markers, human chorionic gonadotropin (hCG) or its subunits, are identifiable in over 90 percent of all extracted neoplasms suggests a critical role for this common denominator of gene derepression in neoplasia. This gene derepression concept in reproductive biology and neoplasia spans many of the basic parameters of human cell replication as related to endocrinology, immunology, biochemistry, electrophysiol ogy, genetics, and pharmacology. The International Society for the Study of Trophoblastic Disease focuses on the global aspects of trophoblast neoplasms. These global aspects include epidemiology and etiology of the disease, regional variations in treatment of trophoblastic neoplasms, and potential ways to adapt and apply Western technology to effective use in developing countries. It was this perspective that formed the basis for the First World Congress on Trophoblast Neoplasms, which convened in Nairobi in October, 1982.


Human Trophoblast Neoplasms

Human Trophoblast Neoplasms
Author: Ronald A Pattillo
Publisher:
Total Pages: 516
Release: 1984-08-01
Genre:
ISBN: 9781468448122

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Molecular Pathology of Gynecologic Cancer

Molecular Pathology of Gynecologic Cancer
Author: Antonio Giordano
Publisher: Springer Science & Business Media
Total Pages: 226
Release: 2007-10-05
Genre: Medical
ISBN: 1597453463

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This book focuses on putting successful molecular strategies into practice for the treatment of gynecologic cancer. It approaches research into the pathology and treatment of gynecologic oncology from both clinical and experimental perspectives. New insights made possible by the introduction of advanced technologies into the field are presented. This new volume will be necessary reading for clinicians and experimental researchers alike.


Diagnostic Molecular Pathology

Diagnostic Molecular Pathology
Author: William B. Coleman
Publisher: Academic Press
Total Pages: 846
Release: 2023-10-27
Genre: Science
ISBN: 0128229934

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Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing, Second Edition assembles a group of experts to discuss the molecular basis and mechanisms of major human diseases and disease processes and how the molecular features of disease can be harnessed to develop practical molecular tests for disease detection, diagnosis and prognosis. The book explains how molecular tests are utilized in the treatment of patients in personalized medicine, highlights new technologies and approaches of applied molecular pathology, and discusses how this discovery-based research yields new and useful biomarkers and tests. As it is essential to stay up-to-date on new molecular diagnostics in this changing field, this book covers critically important areas in the practice of personalized medicine and reflects our understanding of the pathology, pathogenesis and pathophysiology of human disease. Includes new material on mass spectrometry for infectious diseases, microbiome, homology-directed repair for PARPi, whole genome sequencing for constitutional testing, and much more Provides insights on the value of the molecular test in comparison to traditional methods, which include speed, precision, sensitivity and clinical impacts for the patient Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis and classification in the clinical workup of a patient Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for the prognostication of disease


Specialist Training in Oncology E-Book

Specialist Training in Oncology E-Book
Author: Thankamma V Ajithkumar
Publisher: Elsevier Health Sciences
Total Pages: 409
Release: 2011-10-28
Genre: Medical
ISBN: 0723437432

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This textbook of oncology is aimed at specialist registrars in the early phase of their training. The basic concepts of cancer practice is touched upon in undergraduate and junior postgraduate years, but new trainees frequently seek additional resources to boost their knowledge in the field of Oncology. This title offers a concise account of the multidisciplinary management of common cancers and cancer-related problems appropriate to doctors at the start of their careers in this specialty. The content of the book is based on latest available evidence and reflects the training guidelines. Readable and concise style, aimed at the beginner in this specialty. Well illustrated in colour with graphics, clinical photographs and radiographs. Section on research methodology. Approachable design in the ‘Specialist Training in...’ series style.


Placental and Gestational Pathology with Online Resource

Placental and Gestational Pathology with Online Resource
Author: Raymond W. Redline
Publisher: Cambridge University Press
Total Pages: 367
Release: 2018-08-23
Genre: Medical
ISBN: 1316632539

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A guide to identifying disease processes in the placenta affecting pregnancy outcome, with current diagnostic criteria and clinical consequences.


Gestational Trophoblastic Disease

Gestational Trophoblastic Disease
Author: Aron E. Szulman
Publisher: Springer Science & Business Media
Total Pages: 274
Release: 2012-12-06
Genre: Medical
ISBN: 1461246989

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Gestational Trophoblastic Disease is a comprehensive survey by leading clinicians, pathologists, and basic scientists on the most significant developments in diagnosis and treatment of malignant trophoblastic disease ("molar pregnancy"). The book emphasizes partial and complete hydatidiform mole; invasive mole; choriocarcinoma; diagnostic applications of both ultrasonography and laboratory measurement of human chorionic gonadotropin; and chemotherapeutic modalities. The epidemiologic and immunologic aspects of gestational trophoblastic disease are explored, together with the psychological impact on patients and their families. Going beyond descriptive clinical symptomatology, the contributors present an up-to-date summary of knowledge derived from current research.


Gestational Trophoblastic Disease

Gestational Trophoblastic Disease
Author: Bhagyalaxmi Nayak
Publisher: Springer Nature
Total Pages: 163
Release: 2021-02-17
Genre: Medical
ISBN: 981334878X

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This book covers the entire spectrum of gestational trophoblastic disease from the most benign to the most malignant form. It addresses etiopathogenesis, molecular basis of the disease, risk assessment, management and follow-up. Management in the form of surgical, medical and supportive care is discussed in detail to help the practitioner in making treatment decisions. Special and rare varieties of the disease are be dealt separately. A separate section in each chapter covers critical conditions arising from the disease. Case based discussions make the chapters more lively and interesting. The recent trials and studies are also covered in the book. Topics such as fertility preservation, gestational trophoblastic diseases registry and development of voluntary organizations for supporting patients are value additions to this book. This book is meant for the general obstetrician and gynecologist and for the gynaecologic oncologist as well.


Gynaecological Oncology

Gynaecological Oncology
Author: Mahmood I. Shafi
Publisher: Cambridge University Press
Total Pages: 249
Release: 2009-12-03
Genre: Medical
ISBN: 0521730244

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Topics include epidemiology, screening and prevention, pathology, imaging, surgery, radiotherapy, systemic therapies, palliative care, ovarian cancer, endometrial cancer, cervical and vaginal cancer, vulvar cancer, gynaecological sarcomas, gestational trophoblastic disease, ovarian germ cell tumours and decision making in ovarian cancer.


Female Genital Tumours: Who Classification of Tumours

Female Genital Tumours: Who Classification of Tumours
Author: W. H. O. Classification WHO Classification of Tumours Editorial Board
Publisher:
Total Pages: 632
Release: 2020-09-30
Genre: Medical
ISBN: 9789283245049

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****When not purchasing directly from the official sales agents of the WHO, especially at online bookshops, please note that there have been issues with counterfeited copies. Buy only from known sellers and if there are quality issues, please contact the seller for a refund.***** Female Genital Tumours is the fourth volume in the 5th edition of the WHO series on the classification of human tumours. This series (also known as the WHO Blue Books) is regarded as the gold standard for the diagnosis of tumours and comprises a unique synthesis of histopathological diagnosis with digital and molecular pathology. These authoritative and concise reference books provide indispensable international standards for anyone involved in the care of patients with cancer or in cancer research, underpinning individual patient treatment as well as research into all aspects of cancer causation, prevention, therapy, and education. What's new in this edition? The 5th edition, guided by the WHO Classification of Tumours Editorial Board, will establish a single coherent cancer classification presented across a collection of individual volumes organized on the basis of anatomical site (digestive system, breast, soft tissue and bone, etc.) and structured in a systematic manner, with each tumour type listed within a taxonomic classification: site, category, family (class), type, and subtype. In each volume, the entities are now listed from benign to malignant and are described under an updated set of headings, including histopathology, diagnostic molecular pathology, staging, and easy-to-read essential and desirable diagnostic criteria. Who should read this book? - Pathologists - Oncologists - Cancer researchers - Surgeons - Epidemiologists - Cancer registrars This volume - Prepared by 191 authors and editors - Contributors from around the world - More than 850 high-quality images - More than 3100 references