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Human Toxicology of Pesticides

Human Toxicology of Pesticides
Author: Fina P. Kaloyanova
Publisher: CRC Press
Total Pages: 310
Release: 2019-06-04
Genre: Medical
ISBN: 100001312X
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First Published in 1991, this book conducts a systematic analysis of existing information regarding the toxicological effects of pesticides on humans. The book identifies the negative health effects related to exposure to pesticides and the biological changes required to undertake biological monitoring. The book also discusses the importance and magnitude of the problem for different kinds of pesticide applications in different parts of the world, explains the toxicodynamics and clinical picture of acute and chronic intoxications resulting from exposure to different groups of pesticides and selected individual substances, and evaluates existing methods and limitations for assessing human exposure to pesticides. Pesticide manufacturers, occupational health professionals, epidemiologists, environmentalists, government agencies and others concerned with the effects of pesticides on human populations should consider this book essential reading.

Pesticides and Human Health

Pesticides and Human Health
Author: W.H. Hallenbeck
Publisher: Springer Science & Business Media
Total Pages: 172
Release: 2012-12-06
Genre: Technology & Engineering
ISBN: 1461250544
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The impetus for this book came from numerous requests by public and private agencies and citizens for information regarding the human health effects of pes ticide exposures. We have tried to compile a relatively complete, concise sum mary of the acute and chronic health effects and the toxicology of pesticides in a format that provides quick and easy access. This book was written to address the needs of the following groups: medical and public health professionals, tox icologists, environmentalists, industrial hygienists, regulators, producers and users of pesticides, public interest advocates, and the legal profession. Acknowledgments We are indebted to Mr. Christopher J. Wiant, Chief of the Environmental Chemistry Section of the Illinois Department of Public Health. The financial support provided by his office was essential in producing this book. We are also indebted to Dr. Charles Benbrook, former staff member, and Representative George E. Brown, Chairman of the Subcommittee on Depart ment Operations, Research and Foreign Agriculture of the Committee on Agri culture, United States House of Representatives, for their guidance in obtain ing pesticide toxicity data. In the Freedom of Information Office, Office of Pesticide Programs of the United States Environmental Protection Agency, the patience and assistance of Therese Murtagh and Virginia Salzman in obtaining documents are appreciated. Of the numerous individuals who participated in the production of this book, the following merit special recognition for the quality of their research, editing, and critical skills: Mark Loafman, Sue Ramirez, Steve Smith, Sally Burns, and Denise Steurer.

Human Toxicology of Pesticides

Human Toxicology of Pesticides
Author: Fina P. Kaloyanova
Publisher: CRC Press
Total Pages: 208
Release: 1991-10-07
Genre: Medical
ISBN: 9780849351921
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This book conducts a systematic analysis of existing information regarding the toxicological effects of pesticides on humans. The book identifies the negative health effects related to exposure to pesticides and the biological changes required to undertake biological monitoring. The book also discusses the importance and magnitude of the problem for different kinds of pesticide applications in different parts of the world, explains the toxicodynamics and clinical picture of acute and chronic intoxications resulting from exposure to different groups of pesticides and selected individual substances, and evaluates existing methods and limitations for assessing human exposure to pesticides. Pesticide manufacturers, occupational health professionals, epidemiologists, environmentalists, government agencies and others concerned with the effects of pesticides on human populations should consider this book essential reading.

Intentional Human Dosing Studies for EPA Regulatory Purposes

Intentional Human Dosing Studies for EPA Regulatory Purposes
Author: National Research Council
Publisher: National Academies Press
Total Pages: 226
Release: 2004-06-04
Genre: Science
ISBN: 0309166411
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The EPA commissioned The National Academies to provide advice on the vexing question of whether and, if so, under what circumstances EPA should accept and consider intentional human dosing studies conducted by companies or other sources outside the agency (so-called third parties) to gather evidence relating to the risks of a chemical or the conditions under which exposure to it could be judged safe. This report recommends that such studies be conducted and used for regulatory purposes only if all of several strict conditions are met, including the following: The study is necessary and scientifically valid, meaning that it addresses an important regulatory question that can't be answered with animal studies or nondosing human studies; The societal benefits of the study outweigh any anticipated risks to participants. At no time, even when benefits beyond improved regulation exist, can a human dosing study be justified that is anticipated to cause lasting harm to study participants; and All recognized ethical standards and procedures for protecting the interests of study participants are observed. In addition, EPA should establish a Human Studies Review Board (HSRB) to evaluate all human dosing studiesâ€"both at the beginning and upon completion of the experimentsâ€"if they are carried out with the intent of affecting the agency's policy-making.

Pesticide Toxicology

Pesticide Toxicology
Author: Eugenia Gallardo
Publisher:
Total Pages:
Release: 2022
Genre: Electronic books
ISBN: 9781071619285
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This detailed volume explores practical procedures on the identification and quantification of pesticides in a variety of samples. Chapters guide the reader through methods and protocols for the extraction of pesticides from biological and non-biological samples, pitfalls in dosing techniques and structures identification, and also provide an overview of the problems that these pesticides cause in human populations. As part of the Methods in Pharmacology and Toxicology series, chapters include introductions to their respective topics, lists of reagents and materials, step-by-step guides and reproducible lab protocols, as well as valuable tips on addressing common problems and avoiding known pitfalls. Authoritative and practical, Pesticide Toxicology is an ideal reference for academia, analysts, toxicologists, environmentalists, and health and industry professionals aiming to understand the associated risks and to limit the use of these substances and minimize their potential damage to human health and the environment.

Pesticides in the Diets of Infants and Children

Pesticides in the Diets of Infants and Children
Author: National Research Council
Publisher: National Academies Press
Total Pages: 402
Release: 1993-02-01
Genre: Science
ISBN: 0309048753
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Many of the pesticides applied to food crops in this country are present in foods and may pose risks to human health. Current regulations are intended to protect the health of the general population by controlling pesticide use. This book explores whether the present regulatory approaches adequately protect infants and children, who may differ from adults in susceptibility and in dietary exposures to pesticide residues. The committee focuses on four major areas: Susceptibility: Are children more susceptible or less susceptible than adults to the effects of dietary exposure to pesticides? Exposure: What foods do infants and children eat, and which pesticides and how much of them are present in those foods? Is the current information on consumption and residues adequate to estimate exposure? Toxicity: Are toxicity tests in laboratory animals adequate to predict toxicity in human infants and children? Do the extent and type of toxicity of some chemicals vary by species and by age? Assessing risk: How is dietary exposure to pesticide residues associated with response? How can laboratory data on lifetime exposures of animals be used to derive meaningful estimates of risk to children? Does risk accumulate more rapidly during the early years of life? This book will be of interest to policymakers, administrators of research in the public and private sectors, toxicologists, pediatricians and other health professionals, and the pesticide industry.

Hayes' Handbook of Pesticide Toxicology

Hayes' Handbook of Pesticide Toxicology
Author:
Publisher: Academic Press
Total Pages: 2407
Release: 2010-02-15
Genre: Medical
ISBN: 0080922015
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The Handbook of Pesticide Toxicology is a comprehensive, two-volume reference guide to the properties, effects, and regulation of pesticides that provides the latest and most complete information to researchers investigating the environmental, agricultural, veterinary, and human-health impacts of pesticide use. Written by international experts from academia, government, and the private sector, the Handbook of Pesticide Toxicology is an in-depth examination of critical issues related to the need for, use of, and nature of chemicals used in modern pest management. This updated 3e carries on the book’s tradition of serving as the definitive reference on pesticide toxicology and recognizes the seminal contribution of Wayland J. Hayes, Jr., co-Editor of the first edition. Feature: Presents a comprehensive look at all aspects of pesticide toxicology in one reference work. Benefit: Saves researchers time in quickly accessing the very latest definitive details on toxicity of specific pesticides as opposed to searching through thousands of journal articles. Feature: Clear exposition of hazard identification and dose response relationships in each chapter featuring pesticide agents and actions Benefit: Connects the experimental laboratory results to real-life applications in human health, animal health and the environment. Feature: All major classes of pesticide considered. Benefit: Provides relevance to a wider variety of researchers who are conducting comparative work in pesticides or their health impacts. Feature: Different routes of exposure critically evaluated. Benefit: Connects the loop between exposure and harmful affects to those who are researching the affects of pesticides on humans or wildlife.

Pesticide Toxicology and International Regulation

Pesticide Toxicology and International Regulation
Author: Timothy T. Marrs
Publisher: John Wiley & Sons
Total Pages: 592
Release: 2004-04-21
Genre: Medical
ISBN: 0470091665
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This book brings together key features of the toxicology and occupational hazards of pesticides and the way their use is regulated in the main trading regions of the world. There are chapters on each of the main groups of insecticides, namely organochlorines, anticholinesterases and pyrethrins and pyrethroids. The book also covers fungicides and herbicides, as well as more specialised agents such as microbial pesticides. The risks and hazards to humans are considered, both occupational and through the consumption of contaminated foodstuffs. Additionally, clinical aspects of pesticide poisoning are discussed. The possibility of harm from pesticide exposure has led to the development of national and international regulations governing the application of pesticides. The book describes the regulatory systems in three major economic areas: the North American Free Trade Area (USA, Canada and Mexico), the European Union and Japan. This book should be of interest to all individuals working on the development and application of pesticides anywhere in the world. All those involved in the manufacture, regulation and toxicology of pesticides should also benefit from reading this book.

Toxicology of Pesticides

Toxicology of Pesticides
Author: Lucio G. Costa
Publisher: Springer Science & Business Media
Total Pages: 316
Release: 2013-06-29
Genre: Science
ISBN: 3642708986
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The protection of human health and food and fiber resources against the ravages of pests of many sorts is a continuous struggle by all people in the world. The use of chemical pesticides as an aid in this struggle is now also global. These chemicals are deliberately added to the environment for the purpose of killing or injuring some form of life. Because pesticides are generally less selectively toxic than would be desired, non-target species, including humans, must be protected from injury by these chemicals. This can only be achieved by thorough understanding of the comparative toxicology of these compounds, and by minimizing human (and other desirable species) exposure. The latter can only be achieved by sound regulatory policies that utilize scientific principles and data, properly tempered by both gaps in that data and sociologic and economic considerations. This book contains the proceedings of the NATO Advanced Study Institute on "Toxicology of Pesticides: Experimental, Clinical and Regulatory Perspectives" held in Riva del Garda on October 6-15, 1986. This NATO-ASI has been promoted by the School of Public Health and Community Medicine, University of Washington at Seattle, by the Institute of Pharmacological Sciences, University of Milano and by the Giovanni Lorenzini Foundation, and has been sponsored by both the Society of Toxicology (USA) and the Italian Society of Toxicology.

Mode of Action, Metabolism and Toxicology

Mode of Action, Metabolism and Toxicology
Author: S. Matsunaka
Publisher: Elsevier
Total Pages: 582
Release: 2013-10-22
Genre: Science
ISBN: 1483150453
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Pesticide Chemistry: Human Welfare and the Environment, Volume 3: Mode of Action, Metabolism and Toxicology covers the proceeding of the Fifth International Congress of Pesticide Chemistry. This book is organized into three parts that tackle relevant issues regarding the use of pesticide. The opening part tackles topics relevant to the biochemistry of pests and mode of action of pesticides, such as influence of chlorinated and parathyroid insecticide on cellular calcium regulatory mechanisms; behavioral and lethal actions of amidines on invertebrates; and insect chitin synthetase as biochemical probe for insecticidal compounds. The second part encompasses metabolism and degradation of pesticides and xenobiotics and includes topics on propesticides; selective toxicity conferred by activation; and comparative biochemistry of animal, plant, and microorganism oxidases. The last part covers the toxicology of pesticides and xenobiotics, including the role of biochemical studies in modern toxicological assessment of pesticides; neurophysiological and behavioral assessment of pesticide toxicity; and genetic toxicology applied to the assessment of mutagenic, carcinogenic, and teratogenic action of pesticides and related compounds. This book will be of great interest to chemists, biologists, botanists, and entomologists or professionals whose line of work involves the use of pesticides and who are concerned with pesticide side-effects to the users and the environment.