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Public Health Risk Assessment for Human Exposure to Chemicals

Public Health Risk Assessment for Human Exposure to Chemicals
Author: K. Asante-Duah
Publisher: Springer Science & Business Media
Total Pages: 352
Release: 2012-12-06
Genre: Medical
ISBN: 9401004811

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In fact, with the control and containment of most infectious conditions and diseases of the past millennium having been achieved in most developed countries, and with the resultant increase in life expectancies, much more attention seems to have shifted to degenerative health problems. Many of the degenerative health conditions have been linked to thousands of chemicals regularly encountered in human living and occupational/work environments. It is important, therefore, that human health risk assessments are undertaken on a consistent basis - in order to determine the potential impacts of the target chemicals on public health.


A Practical Guide to Toxicology and Human Health Risk Assessment

A Practical Guide to Toxicology and Human Health Risk Assessment
Author: Laura Robinson
Publisher: John Wiley & Sons
Total Pages: 400
Release: 2018-11-05
Genre: Science
ISBN: 1118881907

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Toxicology – the study of the adverse effects of chemicals on living organisms is the cornerstone to all aspects of chemical safety and knowledge of the subject is needed in a wide spectrum of fields from the chemical industry to medicine, emergency services, forensics, and regulatory science. Toxicology involves the study of symptoms, mechanisms, treatments and detection of poisoning ... especially the poisoning of people. The many problems arising from a poor understanding of toxicology and its applications in hazard communication and chemical safety motivated the author’s training courses and webinars, leading to this valuable book. Providing a practical and accessible guide, A Practical Guide to Toxicology and Human Health Risk Assessment enables readers to quickly build up knowledge and understanding of toxicology and its use in hazard identification, which is a fundamental part of chemical risk assessment. The book also covers current toxicological testing strategies and the use of physicochemical test data in hazard identification and exposure assessment. Examples are provided throughout the book to highlight important issues along with a summary of the key points that have been covered in each of the respective chapters. The book concludes with a listing of online resources on toxicology and risk assessment.


Occupational Health and Safety in the Care and Use of Nonhuman Primates

Occupational Health and Safety in the Care and Use of Nonhuman Primates
Author: National Research Council
Publisher: National Academies Press
Total Pages: 180
Release: 2003-06-13
Genre: Science
ISBN: 0309167949

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The field of occupational health and safety constantly changes, especially as it pertains to biomedical research. New infectious hazards are of particular importance at nonhuman-primate facilities. For example, the discovery that B virus can be transmitted via a splash on a mucous membrane raises new concerns that must be addressed, as does the discovery of the Reston strain of Ebola virus in import quarantine facilities in the U.S. The risk of such infectious hazards is best managed through a flexible and comprehensive Occupational Health and Safety Program (OHSP) that can identify and mitigate potential hazards. Occupational Health and Safety in the Care and Use of Nonhuman Primates is intended as a reference for vivarium managers, veterinarians, researchers, safety professionals, and others who are involved in developing or implementing an OHSP that deals with nonhuman primates. The book lists the important features of an OHSP and provides the tools necessary for informed decision-making in developing an optimal program that meets all particular institutional needs.


Possible Health Effects of Exposure to Residential Electric and Magnetic Fields

Possible Health Effects of Exposure to Residential Electric and Magnetic Fields
Author: National Research Council
Publisher: National Academies Press
Total Pages: 379
Release: 1997-03-18
Genre: Science
ISBN: 0309054478

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Can the electric and magnetic fields (EMF) to which people are routinely exposed cause health effects? This volume assesses the data and draws conclusions about the consequences of human exposure to EMF. The committee examines what is known about three kinds of health effects associated with EMF: cancer, primarily childhood leukemia; reproduction and development; and neurobiological effects. This book provides a detailed discussion of hazard identification, dose-response assessment, exposure assessment, and risk characterization for each. Possible Health Effects of Exposure to Residential Electric and Magnetic Fields also discusses the tools available to measure exposure, common types of exposures, and what is known about the effects of exposure. The committee looks at correlations between EMF exposure and carcinogenesis, mutagenesis, neurobehavioral effects, reproductive and developmental effects, effects on melatonin and other neurochemicals, and effects on bone healing and stimulated cell growth.


Quantitative Environmental Risk Analysis for Human Health

Quantitative Environmental Risk Analysis for Human Health
Author: Robert A. Fjeld
Publisher: John Wiley & Sons
Total Pages: 532
Release: 2023-08-29
Genre: Science
ISBN: 1119675405

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QUANTITATIVE ENVIRONMENTAL RISK ANALYSIS FOR HUMAN HEALTH An updated edition of the foundational guide to environmental risk analysis Environmental risk analysis is a systematic process essential for the evaluation, management, and communication of the human health risk posed by the release of contaminants to the environment. Performed correctly, risk analysis is an essential tool in the protection of the public from the health hazards posed by chemical and radioactive contaminants. Cultivating the quantitative skills required to perform risk analysis competently is a critical need. Quantitative Environmental Risk Analysis for Human Health meets this need with a thorough, comprehensive coverage of the fundamental knowledge necessary to assess environmental impacts on human health. It introduces readers to a robust methodology for analyzing environmental risk, as well as to the fundamental principles of uncertainty analysis and the pertinent environmental regulations. Now updated to reflect the latest research and new cutting-edge methodologies, this is an essential contribution to the practice of environmental risk analysis. Readers of the second edition of Quantitative Environmental Risk Analysis for Human Health will also find: Detailed treatment of source and release characterization, contaminant migration, exposure assessment, and more New coverage of computer-based analytical methods A new chapter of case studies providing actual, real-world examples of environmental risk assessments Quantitative Environmental Risk Analysis for Human Health is must-have for graduate and advanced undergraduate students in civil engineering, environmental engineering, and environmental science, as well as for risk analysis practitioners in industry, environmental consultants, and regulators.


Science and Judgment in Risk Assessment

Science and Judgment in Risk Assessment
Author: National Research Council
Publisher: National Academies Press
Total Pages: 668
Release: 1994-01-01
Genre: Science
ISBN: 030904894X

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The public depends on competent risk assessment from the federal government and the scientific community to grapple with the threat of pollution. When risk reports turn out to be overblownâ€"or when risks are overlookedâ€"public skepticism abounds. This comprehensive and readable book explores how the U.S. Environmental Protection Agency (EPA) can improve its risk assessment practices, with a focus on implementation of the 1990 Clean Air Act Amendments. With a wealth of detailed information, pertinent examples, and revealing analysis, the volume explores the "default option" and other basic concepts. It offers two views of EPA operations: The first examines how EPA currently assesses exposure to hazardous air pollutants, evaluates the toxicity of a substance, and characterizes the risk to the public. The second, more holistic, view explores how EPA can improve in several critical areas of risk assessment by focusing on cross-cutting themes and incorporating more scientific judgment. This comprehensive volume will be important to the EPA and other agencies, risk managers, environmental advocates, scientists, faculty, students, and concerned individuals.


Human and Ecological Risk Assessment

Human and Ecological Risk Assessment
Author: Dennis J. Paustenbach
Publisher: John Wiley & Sons
Total Pages: 1476
Release: 2017-05-22
Genre: Science
ISBN: 1119441331

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Human and Ecological Risk Assessment: Theory and Practice assembles the expertise of more than fifty authorities from fifteen different fields, forming a comprehensive reference and textbook on risk assessment. Containing two dozen case studies of environmental or human health risk assessments, the text not only presents the theoretical underpinnings of the discipline, but also serves as a complete handbook and "how-to" guide for individuals conducting or interpreting risk assessments. In addition, more than 4,000 published papers and books in the field are cited. Editor Dennis Paustenbach has assembled chapters that present the most current methods for conducting hazard identification, dose-response and exposure assessment, and risk characterization components for risk assessments of any chemical hazard to humans or wildlife (fish, birds, and terrestrials). Topics addressed include hazards posed by: Air emissions Radiological hazards Contaminated soil and foods Agricultural hazards Occupational hazards Consumer products and water Hazardous waste sites Contaminated air and water The bringing together of so many of the world's authorities on these topics, plus the comprehensive nature of the text, promises to make Human and Ecological Risk Assessment the text against which others will be measured in the coming years.


Quantitative Health Risk Analysis Methods

Quantitative Health Risk Analysis Methods
Author: Louis Anthony Cox Jr.
Publisher: Springer Science & Business Media
Total Pages: 363
Release: 2006-03-17
Genre: Medical
ISBN: 0387261184

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This book grew out of an effort to salvage a potentially useful idea for greatly simplifying traditional quantitative risk assessments of the human health consequences of using antibiotics in food animals. In 2001, the United States FDA’s Center for Veterinary Medicine (CVM) (FDA-CVM, 2001) published a risk assessment model for potential adverse human health consequences of using a certain class of antibiotics, fluoroquinolones, to treat flocks of chickens with fatal respiratory disease caused by infectious bacteria. CVM’s concern was that fluoroquinolones are also used in human medicine, raising the possibility that fluoroquinolone-resistant strains of bacteria selected by use of fluoroquinolones in chickens might infect humans and then prove resistant to treatment with human medicines in the same class of antibiotics, such as ciprofloxacin. As a foundation for its risk assessment model, CVM proposed a dramatically simple approach that skipped many of the steps in traditional risk assessment. The basic idea was to assume that human health risks were directly proportional to some suitably defined exposure metric. In symbols: Risk = K × Exposure, where “Exposure” would be defined in terms of a metric such as total production of chicken contaminated with fluoroquinolone-resistant bacteria that might cause human illnesses, and “Risk” would describe the expected number of cases per year of human illness due to fluoroquinolone-resistant bacterial infections caused by chicken and treated with fluoroquinolones.


Science and Decisions

Science and Decisions
Author: National Research Council
Publisher: National Academies Press
Total Pages: 422
Release: 2009-03-24
Genre: Political Science
ISBN: 0309120462

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Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.