Human Genetic Engineering PDF Download
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| Author | : The Royal Society |
| Publisher | : National Academies Press |
| Total Pages | : 239 |
| Release | : 2021-01-16 |
| Genre | : Medical |
| ISBN | : 0309671132 |
Download Heritable Human Genome Editing Book in PDF, ePub and Kindle
Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.
| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 329 |
| Release | : 2017-08-13 |
| Genre | : Medical |
| ISBN | : 0309452880 |
Download Human Genome Editing Book in PDF, ePub and Kindle
Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.
| Author | : John H. Evans |
| Publisher | : University of Chicago Press |
| Total Pages | : 316 |
| Release | : 2002 |
| Genre | : Science |
| ISBN | : 9780226222615 |
Download Playing God? Book in PDF, ePub and Kindle
AcknowledgmentsIntroduction1. Framework for Understanding the Thinning of a Public Debate2. Setting the Stage: The Eugenicists and the Challenge from Theologians3. Gene Therapy, Advisory Commissions, and the Birth of the Bioethics Profession4. The President's Commission: The "Neutral" Triumph of Formal Rationality5. Regaining Lost Jurisdictional Ground and the Triumph of the Bioethics Profession6. "Reproduction" as the New Jurisdictional Metaphor: Autonomy and the Internal Threat to the Bioethics/Science Jurisdiction7. Conclusion: The Future of Public Bioethics and the HGE DebateAppendix: Methods and TablesNotesWorks CitedIndex Copyright © Libri GmbH. All rights reserved.
| Author | : Pete Shanks |
| Publisher | : Nation Books |
| Total Pages | : 336 |
| Release | : 2005-05-20 |
| Genre | : Medical |
| ISBN | : 9781560256953 |
Download Human Genetic Engineering Book in PDF, ePub and Kindle
The debate over human Genetic Engineering (GE) is about to go mainstream. Not as a one-day wonder about cloning or a theological disagreement about embryos, but as a major political issue, driven in part by a grassroots movement of opposition. Human Genetic Engineering is a highly readable and entertaining guide. It explains in accessible language for a popular audience the essential questions that will arise in the future debates: What is human GE? Will it work? What perspectives should we remember? Who is doing what, and why?
| Author | : Jamie Metzl |
| Publisher | : Sourcebooks, Inc. |
| Total Pages | : 251 |
| Release | : 2019-04-23 |
| Genre | : Science |
| ISBN | : 1492670103 |
Download Hacking Darwin Book in PDF, ePub and Kindle
"A gifted and thoughtful writer, Metzl brings us to the frontiers of biology and technology, and reveals a world full of promise and peril." — Siddhartha Mukherjee MD, New York Times bestselling author of The Emperor of All Maladies and The Gene A groundbreaking exploration of genetic engineering and its impact on the future of our species from leading geopolitical expert and technology futurist, Jamie Metzl. At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race. Enter the laboratories where scientists are turning science fiction into reality. In this captivating and thought-provoking nonfiction science book, Jamie Metzl delves into the ethical, scientific, political, and technological dimensions of genetic engineering, and shares how it will shape the course of human evolution. Cutting-edge insights into the field of genetic engineering and its implications for humanity's future Explores the transformative power of genetic technologies and their potential to reshape human life Examines the ethical considerations surrounding genetic engineering and the choices we face as a species Engaging narrative that delves into the scientific breakthroughs and real-world applications of genetic technologies Provides a balanced perspective on the promises and risks associated with genetic engineering Raises thought-provoking questions about the future of reproduction, human health, and our relationship with nature Drawing on his extensive background in genetics, national security, and foreign policy, Metzl paints a vivid picture of a world where advancements in technology empower us to take control of our own evolution, but also cautions against the pitfalls and ethical dilemmas that could arise if not properly managed. Hacking Darwin is a must-read for anyone interested in the intersection of science, technology, and humanity's future.
| Author | : Andrea Boggio |
| Publisher | : Cambridge University Press |
| Total Pages | : 681 |
| Release | : 2020-01-09 |
| Genre | : Law |
| ISBN | : 1108499872 |
Download Human Germline Modification and the Right to Science Book in PDF, ePub and Kindle
A survey of the regulation of human germline genome modification in eighteen countries and the emerging international standards.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 254 |
| Release | : 2004-07-08 |
| Genre | : Science |
| ISBN | : 0309166152 |
Download Safety of Genetically Engineered Foods Book in PDF, ePub and Kindle
Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre- and post-market approaches to guide the assessment of unintended compositional changes that could result from genetically modified foods and research avenues to fill the knowledge gaps.
| Author | : Michael J Sandel |
| Publisher | : Harvard University Press |
| Total Pages | : 177 |
| Release | : 2009-06-30 |
| Genre | : Philosophy |
| ISBN | : 0674043065 |
Download The Case against Perfection Book in PDF, ePub and Kindle
Breakthroughs in genetics present us with a promise and a predicament. The promise is that we will soon be able to treat and prevent a host of debilitating diseases. The predicament is that our newfound genetic knowledge may enable us to manipulate our nature—to enhance our genetic traits and those of our children. Although most people find at least some forms of genetic engineering disquieting, it is not easy to articulate why. What is wrong with re-engineering our nature? The Case against Perfection explores these and other moral quandaries connected with the quest to perfect ourselves and our children. Michael Sandel argues that the pursuit of perfection is flawed for reasons that go beyond safety and fairness. The drive to enhance human nature through genetic technologies is objectionable because it represents a bid for mastery and dominion that fails to appreciate the gifted character of human powers and achievements. Carrying us beyond familiar terms of political discourse, this book contends that the genetic revolution will change the way philosophers discuss ethics and will force spiritual questions back onto the political agenda. In order to grapple with the ethics of enhancement, we need to confront questions largely lost from view in the modern world. Since these questions verge on theology, modern philosophers and political theorists tend to shrink from them. But our new powers of biotechnology make these questions unavoidable. Addressing them is the task of this book, by one of America’s preeminent moral and political thinkers.
| Author | : Roberta M. Berry |
| Publisher | : Routledge |
| Total Pages | : 282 |
| Release | : 2013-05-13 |
| Genre | : Medical |
| ISBN | : 1135195919 |
Download The Ethics of Genetic Engineering Book in PDF, ePub and Kindle
Human genetic engineering may soon be possible. The gathering debate about this prospect already threatens to become mired in irresolvable disagreement. After surveying the scientific and technological developments that have brought us to this pass, The Ethics of Genetic Engineering focuses on the ethical and policy debate, noting the deep divide that separates proponents and opponents. The book locates the source of this divide in differing framing assumptions: reductionist pluralist on one side, holist communitarian on the other. The book argues that we must bridge this divide, drawing on the resources from both encampments, if we are to understand and cope with the distinctive problems posed by genetic engineering. These problems, termed "fractious problems," are novel, complex, ethically fraught, unavoidably of public concern, and unavoidably divisive. Berry examines three prominent ethical and political theories – utilitarianism, Kantianism, and virtue ethics – to consider their competency in bridging the divide and addressing these fractious problems. The book concludes that virtue ethics can best guide parental decision making and that a new policymaking approach sketched here, a "navigational approach," can best guide policymaking. These approaches enable us to gain a rich understanding of the problems posed and to craft resolutions adequate to their challenges.
| Author | : Donald Bruce |
| Publisher | : Routledge |
| Total Pages | : 354 |
| Release | : 2014-01-27 |
| Genre | : Medical |
| ISBN | : 1317972384 |
Download Engineering Genesis Book in PDF, ePub and Kindle
Few issues have aroused so much public attention and controversy as recent developments in biotechnology. How can we make sound judgements of the cloning of Dolly the sheep, genetically altered foodstuffs, or the prospect of transplanting pigs' hearts into humans? Are we 'playing God' with nature? What is driving these developments, and how can they be made more accountable to the public? Engineering Genesis provides a uniquely informed, balanced and varied insight into these and many other key issues from a working group of distinguished experts - in genetics, agriculture, animal welfare, ethics, theology, sociology and risk - brought together by the Society, Religion and Technology Project of the Church of Scotland. A number of case studies present all the main innovations: animal cloning, pharmaceutical production from animals, cross-species transplants, and, genetically modified foods. From these the authors develop a careful analysis of the ethical and social implications - offering contrasting perspectives and insightful arguments which, above all, will enable readers to form their own judgements on these vital questions.
