Hplc Methods On Drug Analysis PDF Download
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| Author | : Mantu K. Ghosh |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 599 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 3642765068 |
Download HPLC Methods on Drug Analysis Book in PDF, ePub and Kindle
The dramatic development of chromatographic techniques, specially high per formance or high pressure liquid chromatography (HPLC) has made possible the easy analysis of organic compounds, including drugs and drug components, for last two decades. This rapid increase and improvement of analytical methodology with HPLC has enabled researchers and scientists to cope with other scientific and instru mental developments in their fields of work. Thousands of impressive and original scientific publications, text books and monographs describe the techniques for drug analysis with high performance liquid chromatography. However, no concise presentation of the general proper ties of the drugs and their HPLC methodology exists together in the market. This work contains the general properties necessary for the analysis of 232 drugs as well as the HPLC methods for many other drugs and drug components. It is hoped that it will fill a gap and provide a precise survey of the HPLC methods for drug analysis. It is intended as an immediate guide in the laboratory and will be of help to the scientists, researchers and technicians in the field of analysis.
| Author | : Hermann Mascher |
| Publisher | : John Wiley & Sons |
| Total Pages | : 0 |
| Release | : 2012-02-13 |
| Genre | : Science |
| ISBN | : 3527331298 |
Download HPLC Methods for Clinical Pharmaceutical Analysis Book in PDF, ePub and Kindle
Filling a gap in the literature for a hands-on guide focusing on everyday laboratory challenges, this English edition has been expanded and revised using the feedback received on the successful German precursor. Throughout the book, Professor Mascher draws on his 30 years of experience and provides abundant practical advice, troubleshooting and other hints highlighted in boxes, as well as a broad selection of walkthrough case studies. Based on a course taught by the author, the first part of the book intuitively explains all steps of routine bioanalysis and explains how to set up a robust, inexpensive and effi cient method for a given substance. In the second part he includes 20 worked example cases that highlight common challenges and how to overcome them. With its appendix containing tried-and-tested analytical methods for 100 clinically relevant substances from the author`s own laboratory, complete with spectral and MS data as well as literature references and basic pharmacokinetic information, this is a life-long companion for everyone working in clinical, pharmaceutical and biochemical analysis. Comments to the German book: "The book comes to life through its examples, showing not only what did work in the author's laboratory, but also what didn't." ChemieReport "Indispensable for novices, while even old hands will be able to expand their knowledge. A collection of analytical data for ca. 100 substances completes the book's offering, leaving almost nothing to be desired." pharmind
| Author | : George Lunn |
| Publisher | : Wiley-Interscience |
| Total Pages | : 0 |
| Release | : 2000-01-21 |
| Genre | : Science |
| ISBN | : 9780471332961 |
Download HPLC Methods for Pharmaceutical Analysis, Volumes 2-4 Book in PDF, ePub and Kindle
The most commonly used method for analyzing substances, and the first method most researchers turn to, is high performance liquid chromatography (HPLC). Following up on a best-seller, volumes 2-4 continue to provide an easily-accessible collection of procedures for analyzing pharmaceuticals using HPLC.
| Author | : Quanyun A. Xu |
| Publisher | : Pharmaceutical Press |
| Total Pages | : 936 |
| Release | : 2008 |
| Genre | : Medical |
| ISBN | : |
Download Stability-indicating HPLC Methods for Drug Analysis Book in PDF, ePub and Kindle
Stability-Indicating HPLC Methods for Drug Analysis compiles summaries of stability-indicating HPLC analytical methods that have appeared in the published literature. A first stop for pharmaceutical scientists, analytical chemists, and librarians in the quest for information about the stability of drugs. Co-published by the American Pharmaceutical Association and the Pharmaceutical Press, a division of the Royal Pharmaceutical Society of Great Britain.
| Author | : Satinder Ahuja |
| Publisher | : Elsevier |
| Total Pages | : 679 |
| Release | : 2005-02-09 |
| Genre | : Medical |
| ISBN | : 0080455182 |
Download Handbook of Pharmaceutical Analysis by HPLC Book in PDF, ePub and Kindle
High pressure liquid chromatography–frequently called high performance liquid chromatography (HPLC or, LC) is the premier analytical technique in pharmaceutical analysis and is predominantly used in the pharmaceutical industry. Written by selected experts in their respective fields, the Handbook of Pharmaceutical Analysis by HPLC Volume 6, provides a complete yet concise reference guide for utilizing the versatility of HPLC in drug development and quality control. Highlighting novel approaches in HPLC and the latest developments in hyphenated techniques, the book captures the essence of major pharmaceutical applications (assays, stability testing, impurity testing, dissolution testing, cleaning validation, high-throughput screening). A complete reference guide to HPLC Describes best practices in HPLC and offers 'tricks of the trade' in HPLC operation and method development Reviews key HPLC pharmaceutical applications and highlights currents trends in HPLC ancillary techniques, sample preparations, and data handling
| Author | : Satinder Ahuja |
| Publisher | : Elsevier |
| Total Pages | : 532 |
| Release | : 2011-09-21 |
| Genre | : Medical |
| ISBN | : 0080554199 |
Download HPLC Method Development for Pharmaceuticals Book in PDF, ePub and Kindle
High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective. HPLC Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge. Covers the requirements for HPLC in a pharmaceutical setting including strategies for software and hardware validation to allow for use in a regulated laboratory Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities) Discusses how HPLC is used in each phase of pharmaceutical development and how methods are developed to support activities in each phase
| Author | : Oona McPolin |
| Publisher | : Lulu.com |
| Total Pages | : 150 |
| Release | : 2009-03-01 |
| Genre | : Medical |
| ISBN | : 0956152805 |
Download An Introduction to HPLC for Pharmaceutical Analysis Book in PDF, ePub and Kindle
If you are new to HPLC, this book provides an invaluable guide to how HPLC is actually used when analysing pharmaceuticals. It is full of practical advice on the operation of HPLC systems combined with the necessary theoretical knowledge to ensure understanding of the technique. Key features include: A thorough discussion of the stationary phase enabling the reader to make sense of the many parameters used to describe a HPLC column; Practical advice and helpful hints for the preparation and use of mobile phase; A complete overview of each of the different components which together make up a HPLC system; A description of the contents of a typical HPLC analytical method and how to interpret these; A step-by-step guide on how to follow a method and set up a HPLC analysis; A discussion of system suitability criteria and how to interpret the values obtained during an analysis; Explanation of the common methods of calibration and quantification used for pharmaceutical analysis.
| Author | : George Lunn |
| Publisher | : John Wiley & Sons |
| Total Pages | : 743 |
| Release | : 2005-05-06 |
| Genre | : Science |
| ISBN | : 0471711675 |
Download HPLC Methods for Recently Approved Pharmaceuticals Book in PDF, ePub and Kindle
An indispensable resource for busy researchers Your time is valuable-too valuable to spend hunting through the technical literature in search of the right HPLC assay techniques for your projects. With HPLC Methods for Recently Approved Pharmaceuticals, you'll quickly identify and replicate the ideal procedures for your project needs, without having to refer to original source publications. More of your time can then be spent in the lab, not the library. Covering the relevant world literature through 2003, this book picks up where Dr. Lunn's acclaimed HPLC Methods for Pharmaceutical Analysis left off. It arms you with established HPLC assay techniques for hundreds of newly approved drugs, as well as drugs for which assay methods were only recently developed. Combining detailed descriptions of procedures with specially annotated references, this practical handbook gives you: * HPLC methods for 390 commonly prescribed pharmaceutical compounds * Various procedures for each drug listed together-making it easy to mix and match for customized approaches * Methods for drugs in biological fluids and for bulk and formulated drugs * Chemical structures, molecular weights and formulas, and CAS Registry Numbers * Cross-references to The Merck Index * Retention times of other drugs that can be assayed using the same methods
| Author | : Yuri V. Kazakevich |
| Publisher | : John Wiley & Sons |
| Total Pages | : 1136 |
| Release | : 2007-02-16 |
| Genre | : Science |
| ISBN | : 0470087943 |
Download HPLC for Pharmaceutical Scientists Book in PDF, ePub and Kindle
HPLC for Pharmaceutical Scientists is an excellent book for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. It provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry. In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided. This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development. The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed.
| Author | : George Lunn |
| Publisher | : Wiley-Interscience |
| Total Pages | : 1906 |
| Release | : 1997 |
| Genre | : Medical |
| ISBN | : |
Download HPLC Methods for Pharmaceutical Analysis Book in PDF, ePub and Kindle
Full text included in Knovel Library within the subject area of Chemistry and Chemical Engineering.
