Homeostatic Control Of Brain Function PDF Download
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Author | : Detlev Boison |
Publisher | : Oxford University Press |
Total Pages | : 657 |
Release | : 2016 |
Genre | : Medical |
ISBN | : 0199322295 |
Download Homeostatic Control of Brain Function Book in PDF, ePub and Kindle
Homeostatic Control of Brain Function offers a broad view of brain health and diverse perspectives for potential treatments, targeting key areas such as mitochondria, the immune system, epigenetic changes, and regulatory molecules such as ions, neuropeptides, and neuromodulators. Loss of homeostasis becomes expressed as a diverse array of neurological disorders. Each disorder has multiple comorbidities - with some crossing over several conditions - and often disease-specific treatments remain elusive. When current pharmacological therapies result in ineffective and inadequate outcomes, therapies to restore and maintain homeostatic functions can help improve brain health, no matter the diagnosis. Employing homeostatic therapies may lead to future cures or treatments that address multiple comorbidities. In an age where brain diseases such as Alzheimer's or Parkinson's are ever present, the incorporation of homeostatic techniques could successfully promote better overall brain health. Key Features include · A focus on the homeostatic controls that significantly depend on the way one lives, eats, and drinks. · Highlights from emerging research in non-pharmaceutical therapies including botanical medications, meditation, diet, and exercise. · Incorporation of homeostatic therapies into existing basic and clinical research paradigms. · Extensive scientific basic and clinical research ranging from molecules to disorders. · Emerging practical information for improving homeostasis. · Examples of homeostatic therapies in preventing and delaying dysfunction. Both editors, Detlev Boison and Susan Masino, bring their unique expertise in homeostatic research to the overall scope of this work. This book is accessible to all with an interest in brain health; scientist, clinician, student, and lay reader alike.
Author | : Detlev Boison |
Publisher | : Frontiers Media SA |
Total Pages | : 206 |
Release | : 2017-10-03 |
Genre | : Electronic book |
ISBN | : 2889452867 |
Download Metabolic Control of Brain Homeostasis Book in PDF, ePub and Kindle
Brain function is under metabolic control, which in turn determines the equilibrium of homeostatic systems that affect neuronal and glial networks on the molecular, cellular, and systems levels. The collection of articles ranges from molecules and mechanisms involved in regulating homeostasis and neuronal excitability to therapeutic mechanisms tailored to restore homeostatic function. It also features neurological diseases and novel treatment approaches that are based on metabolic and homeostatic interventions. Together, the collection of articles outlines novel strategies to restore brain function in neurology and highlights limitations of conventional pharmacological approaches. We suggest that restoration of molecular and biochemical networks could lead to a new era of therapeutic opportunities.
Author | : Eric John Parkins |
Publisher | : Routledge |
Total Pages | : 284 |
Release | : 2021-11-22 |
Genre | : Psychology |
ISBN | : 1000481123 |
Download Cerebellum and Cerebrum in Homeostatic Control and Cognition Book in PDF, ePub and Kindle
Cerebellum and Cerebrum in Homeostatic Control and Cognition presents a ground-breaking hybrid-brain psychology, proposing that the cerebellum and cerebrum operate in a complementary manner as equal cognitive partners in learning based control. The book synthesises contemporary neuroscience and psychology in terms of their common underlying control principle, homeostasis. Drawing on research and theory from neuroscience, psychology, AI and robotics, it provides a hybrid control systems interpretation of consciousness and self; unconscious mind; REM dream sleep; emotion; self-monitoring and self-control; memory, infantile amnesia; and, cognitive development. This is used to investigate different elements of cerebellum-cerebrum offline interaction; including attention and working memory, and explores cerebellar and cerebral contributions to various aspects of a number of disorders; including ADHD, ASD and schizophrenia. Presenting original ideas around neuropsychological architecture, the book will be of great interest to academics, researchers, and post-graduate students in the fields of neuropsychology, cognitive psychology, neuroscience and clinical psychology.
Author | : Wolfgang Walz |
Publisher | : Springer Science & Business Media |
Total Pages | : 429 |
Release | : 2001-12-26 |
Genre | : Medical |
ISBN | : 1592591086 |
Download The Neuronal Environment Book in PDF, ePub and Kindle
Leading neuroscience researchers offer a fresh perspective on neuronal function by examining all its many components-including their pertubation during major disease states-and relate each element to neuronal demands. Topics range from the dependency of neurons on metabolic supply, as well as on both ion and transmitter homeostasis, to their close interaction with the myelin sheath. Also addressed are the astrocytic signaling system that controls synaptic transmission, the extracellular matrix and space as communication systems, the role of blood flow regulation in neuronal demand and in blood-brain barrier function, and inflammation and the neuroimmune system. Insightful and integrative, The Neuronal Environment: Brain Homeostasis in Health and Disease demonstrates a clear new understanding that neurons do not work in isolation, that they need constant interactions with other brain components to process information, and that they are not the only information processing system in the brain.
Author | : National Research Council |
Publisher | : National Academies Press |
Total Pages | : 285 |
Release | : 2000-04-18 |
Genre | : Social Science |
ISBN | : 0309172195 |
Download The Aging Mind Book in PDF, ePub and Kindle
Possible new breakthroughs in understanding the aging mind that can be used to benefit older people are now emerging from research. This volume identifies the key scientific advances and the opportunities they bring. For example, science has learned that among older adults who do not suffer from Alzheimer's disease or other dementias, cognitive decline may depend less on loss of brain cells than on changes in the health of neurons and neural networks. Research on the processes that maintain neural health shows promise of revealing new ways to promote cognitive functioning in older people. Research is also showing how cognitive functioning depends on the conjunction of biology and culture. The ways older people adapt to changes in their nervous systems, and perhaps the changes themselves, are shaped by past life experiences, present living situations, changing motives, cultural expectations, and emerging technology, as well as by their physical health status and sensory-motor capabilities. Improved understanding of how physical and contextual factors interact can help explain why some cognitive functions are impaired in aging while others are spared and why cognitive capability is impaired in some older adults and spared in others. On the basis of these exciting findings, the report makes specific recommends that the U.S. government support three major new initiatives as the next steps for research.
Author | : Laurival Antonio De Luca Jr. |
Publisher | : CRC Press |
Total Pages | : 340 |
Release | : 2013-10-01 |
Genre | : Science |
ISBN | : 1466506938 |
Download Neurobiology of Body Fluid Homeostasis Book in PDF, ePub and Kindle
A timely symposium entitled Body-Fluid Homeostasis: Transduction and Integration was held at Araraquara, São Paulo, Brazil in 2011. This meeting was convened as an official satellite of a joint gathering of the International Society for Autonomic Neuroscience (ISAN) and the American Autonomic Society (AAS) held in Buzios, Rio de Janeiro. Broad international participation at this event generated stimulating discussion among the invited speakers, leading to the publication of Neurobiology of Body Fluid Homeostasis: Transduction and Integration. Drawn from the proceedings and filled with rich examples of integrative neurobiology and regulatory physiology, this volume: Provides updated research using human and animal models for the control of bodily fluids, thirst, and salt appetite Explores neural and endocrine control of body fluid balance, arterial pressure, thermoregulation, and ingestive behavior Discusses recent developments in molecular genetics, cell biology, and behavioral plasticity Reviews key aspects of brain serotonin and steroid and peptide control of fluid consumption and arterial pressure The book highlights research conducted by leading scientists on signal transduction and sensory afferent mechanisms, molecular genetics, perinatal and adult long-term influences on regulation, central neural integrative circuitry, and autonomic/neuroendocrine effector systems. The findings discussed by the learned contributors are relevant for a basic understanding of disorders such as heat injury, hypertension, and excess salt intake. A unique reference on the neurobiology of body fluid homeostasis, this volume is certain to fuel additional research and stimulate further debate on the topic.
Author | : J. Gordon Betts |
Publisher | : |
Total Pages | : 0 |
Release | : 2013-04-25 |
Genre | : |
ISBN | : 9781947172807 |
Download Anatomy and Physiology Book in PDF, ePub and Kindle
Author | : Robert Vink |
Publisher | : University of Adelaide Press |
Total Pages | : 354 |
Release | : 2011 |
Genre | : Medical |
ISBN | : 0987073052 |
Download Magnesium in the Central Nervous System Book in PDF, ePub and Kindle
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Author | : William R. Lovallo |
Publisher | : SAGE Publications |
Total Pages | : 366 |
Release | : 2015-01-29 |
Genre | : Psychology |
ISBN | : 1483378284 |
Download Stress and Health Book in PDF, ePub and Kindle
Stress and Health: Biological and Psychological Interactions is a brief and accessible examination of psychological stress and its psychophysiological relationships with cognition, emotions, brain functions, and the peripheral mechanisms by which the body is regulated. Updated throughout, the Third Edition covers two new and significant areas of emerging research: how our early life experiences alter key stress responsive systems at the level of gene expression; and what large, normal, and small stress responses may mean for our overall health and well-being.
Author | : Carl Faingold |
Publisher | : Academic Press |
Total Pages | : 537 |
Release | : 2013-12-26 |
Genre | : Medical |
ISBN | : 0124158641 |
Download Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics Book in PDF, ePub and Kindle
Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: How the brain carries out important tasks via networks How these networks interact in normal brain function Major mechanisms that control network function The interaction of the normal networks to produce more complex behaviors How brain disorders can result from abnormal interactions How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders. Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available