HIV Molecular Immunology 2001
Author | : |
Publisher | : DIANE Publishing |
Total Pages | : 915 |
Release | : 2001 |
Genre | : |
ISBN | : 1428918140 |
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Author | : |
Publisher | : DIANE Publishing |
Total Pages | : 915 |
Release | : 2001 |
Genre | : |
ISBN | : 1428918140 |
Author | : |
Publisher | : |
Total Pages | : 694 |
Release | : 2003 |
Genre | : AIDS (Diseases) |
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Author | : |
Publisher | : |
Total Pages | : 754 |
Release | : 1998 |
Genre | : AIDS (Disease) |
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Author | : |
Publisher | : |
Total Pages | : 3301 |
Release | : 2015 |
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HIV Molecular Immunology is a companion volume to HIV Sequence Compendium. This publication, the 2014 edition, is the PDF version of the web-based HIV Immunology Database (http://www.hiv.lanl.gov/content/immunology/). The web interface for this relational database has many search options, as well as interactive tools to help immunologists design reagents and interpret their results. In the HIV Immunology Database, HIV-specific B-cell and T-cell responses are summarized and annotated. Immunological responses are divided into three parts, CTL, T helper, and antibody. Within these parts, defined epitopes are organized by protein and binding sites within each protein, moving from left to right through the coding regions spanning the HIV genome. We include human responses to natural HIV infections, as well as vaccine studies in a range of animal models and human trials. Responses that are not specifically defined, such as responses to whole proteins or monoclonal antibody responses to discontinuous epitopes, are summarized at the end of each protein section. Studies describing general HIV responses to the virus, but not to any specific protein, are included at the end of each part. The annotation includes information such as crossreactivity, escape mutations, antibody sequence, TCR usage, functional domains that overlap with an epitope, immune response associations with rates of progression and therapy, and how specific epitopes were experimentally defined. Basic information such as HLA specificities for T-cell epitopes, isotypes of monoclonal antibodies, and epitope sequences are included whenever possible. All studies that we can find that incorporate the use of a specific monoclonal antibody are included in the entry for that antibody. A single T-cell epitope can have multiple entries, generally one entry per study. Finally, maps of all defined linear epitopes relative to the HXB2 reference proteins are provided.
Author | : |
Publisher | : |
Total Pages | : 582 |
Release | : 2005 |
Genre | : AIDS (Disease) |
ISBN | : |
Author | : |
Publisher | : |
Total Pages | : |
Release | : 2000 |
Genre | : AIDS (Disease) |
ISBN | : |
Author | : |
Publisher | : DIANE Publishing |
Total Pages | : 940 |
Release | : 2002 |
Genre | : |
ISBN | : 1428918132 |
Author | : |
Publisher | : |
Total Pages | : 702 |
Release | : 2006 |
Genre | : AIDS (Disease) |
ISBN | : |
Author | : Guido Silvestri |
Publisher | : Springer |
Total Pages | : 248 |
Release | : 2018-10-11 |
Genre | : Medical |
ISBN | : 303002816X |
This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.
Author | : Steven A. Frank |
Publisher | : Princeton University Press |
Total Pages | : 364 |
Release | : 2002-07-21 |
Genre | : Medical |
ISBN | : 9780691095950 |
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