The Hereditary Hemolytic Anemias
Author | : William C. Mentzer |
Publisher | : |
Total Pages | : 496 |
Release | : 1989 |
Genre | : Medical |
ISBN | : |
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Author | : William C. Mentzer |
Publisher | : |
Total Pages | : 496 |
Release | : 1989 |
Genre | : Medical |
ISBN | : |
Author | : Richard Van Wijk |
Publisher | : Frontiers Media SA |
Total Pages | : 141 |
Release | : 2020-12-23 |
Genre | : Science |
ISBN | : 2889662705 |
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author | : Source Wikipedia |
Publisher | : Booksllc.Net |
Total Pages | : 30 |
Release | : 2013-09 |
Genre | : |
ISBN | : 9781230823027 |
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Pages: 28. Chapters: Alpha-thalassemia, Beta-thalassemia, Congenital hemolytic anemia, Delta-thalassemia, Glucose-6-phosphate dehydrogenase deficiency, Hemoglobinopathy, Hereditary elliptocytosis, Hereditary persistence of fetal hemoglobin, Hereditary spherocytosis, Hereditary stomatocytosis, Hexokinase deficiency, Minkowski-Chauffard syndrome, Pyruvate kinase deficiency, Sickle-cell disease, Sickle cell trait, Southeast Asian ovalocytosis, Triosephosphate isomerase deficiency. Excerpt: Sickle-cell disease (SCD), or sickle-cell anaemia (SCA) or drepanocytosis, is an autosomal recessive genetic blood disorder with overdominance, characterized by red blood cells that assume an abnormal, rigid, sickle shape. Sickling decreases the cells' flexibility and results in a risk of various complications. The sickling occurs because of a mutation in the hemoglobin gene. Life expectancy is shortened. In 1994, in the US, the average life expectancy of persons with this condition was estimated to be 42 years in males and 48 years in females, but today, thanks to better management of the disease, patients can live into their 80s or beyond. Sickle-cell disease occurs more commonly among people whose ancestors lived in tropical and sub-tropical sub-saharan regions where malaria is or was common. Where malaria is common, carrying a single sickle-cell gene (sickle cell trait) confers a fitness. Specifically, humans with one of the two alleles of sickle-cell disease show less severe symptoms when infected with malaria. Sickle-cell anaemia is a form of sickle-cell disease in which there is homozygosity for the mutation that causes HbS. Sickle-cell anaemia is also referred to as "HbSS," "SS disease," "haemoglobin S" or permutations of those names. In heterozygous people, that is, those who have only one sickle gene and one normal adult haemoglobin gene, the...
Author | : Martha Pritchett Mims, MD, PhD |
Publisher | : Springer Publishing Company |
Total Pages | : 555 |
Release | : 2019-12-11 |
Genre | : Medical |
ISBN | : 0826149871 |
Handbook of Benign Hematology is a practical guide to the diagnosis and management of benign hematologic conditions. The book begins with a chapter on normal hematopoiesis and follows with chapters devoted to groups of blood disorders and syndromes including neutrophil disorders, nonmalignant myeloid disorders, bone marrow failure syndromes, myeloproliferative disorders, anemias, iron metabolism disorders, platelet disorders, hemostasis and coagulation defects, and thrombosis. Each disorder subtype covered features a clinical case, an introduction to the condition, details on diagnosis including applicable criteria and lab work needed, key diagnostic dilemmas, prognosis, treatment options, details on clinical trials and emerging clinical strategies, and bulleted key points to highlight clinical pearls and common pitfalls. The final chapters provide best practices for transfusion medicine and a guide to pharmacologic agents and their uses in clinical practice for adult and pediatric patients. The handbook is filled with tables and illustrations which highlight FDA-approved drug information, clinical trials data, hematopathologic characteristics of different disorders, important management criteria and more, making it the ideal handbook for those in practice or for review. The Editors and chapter authors are experienced academic practitioners in the fields of adult and pediatric hematology, pathology, blood banking, and pharmacology. Emphasizing best practices for patient management, this handbook is essential for oncologists, hematologists, trainees, and other practitioners who regularly or increasingly receive referrals to diagnose and treat adults or children with nonmalignant hematologic conditions. Key Features: Includes dozens of clinical cases covering all nonmalignant blood disorders Emphasizes patient management and best practices for disorders seen in adults and children Contains over 30 color images and numerous tables for quick reference Presents important details of all pharmacologic agents used to treat or manage hematologic disorders and their complications Purchase includes access to the ebook for use on most mobile devices or computers
Author | : Sue Pavord |
Publisher | : Cambridge University Press |
Total Pages | : 362 |
Release | : 2018-02-08 |
Genre | : Medical |
ISBN | : 1108548377 |
Understand the rapidly growing complexities of obstetric hematology and high-risk pregnancy management, with experts in the field. Now in its second edition, this comprehensive and essential guide focuses on providing the best support for patients and clinical staff, to prevent serious complications in pregnancy and the post-partum period for both mother and baby. Wide-ranging and detailed, the guide offers discussions on basic principles of best care, through to tackling lesser-known hematological conditions, such as cytopenias and hemoglobinopathies. Updated with color illustrations, cutting-edge research, accurate blood film reproductions, and practical case studies, the revised edition places invaluable advice into everyday context. This unique resource is essential reading for trainees and practitioners in obstetrics, anesthesia, and hematology, as well as midwives, nurses, and laboratory staff. Clarifying difficult procedures for disease prevention, the guide ensures safety when the stakes are high. Reflecting current evidence-based guidelines, the updated volume is key to improving pregnancy outcomes worldwide.
Author | : Hillard M. Lazarus |
Publisher | : Springer |
Total Pages | : 542 |
Release | : 2018-11-15 |
Genre | : Medical |
ISBN | : 331997873X |
This text provides a comprehensive overview of the essential concepts and malignancies of hematology. Now in its second edition, the book reviews every major hematologic disorder and disease entity in thorough detail, from incidence and prevalence to patient and treatment-related issues. Formatted in an organized and easy-to-read outline style to facilitate rapid learning and information processing, the book allows readers to easily locate topics of immediate interest without wading through entire sections to obtain the desired data. Written by a diverse range of experts in the field, Concise Guide to Hematology, Second Edition is a valuable resource for clinicians, residents, trainees, and entry-level fellows who work in or are just entering the field of hematology.
Author | : Pedro A. de Alarcón |
Publisher | : Cambridge University Press |
Total Pages | : 501 |
Release | : 2021-02-18 |
Genre | : Medical |
ISBN | : 1108488986 |
An essential guide to the pathogenesis, diagnosis and management of hematologic problems in the neonate, covering erythrocyte disorders, leukocyte disorders, immunologic disorders and hemostatic disorders. Guidance is practical, including blood test interpretation, advice on transfusions and reference ranges for hematological values.
Author | : Robert T. Means Jr. |
Publisher | : Springer |
Total Pages | : 219 |
Release | : 2018-11-13 |
Genre | : Medical |
ISBN | : 3319964879 |
This text provides a concise yet comprehensive overview of anemia in the young and old. The first section of the volume features age-specific diagnostic approaches to anemia, from the perinatal period to the elderly, with a particular emphasis on age-specific epidemiology, differential diagnosis, and testing. The second section focuses on specific anemia disorders, including inherited bone marrow failure syndromes, iron deficiency anemia, renal anemia, pure red cell anemia, and anemia of inflammation and chronic disease. Each chapter in this section revolves around a specific syndrome or group of syndromes, and addresses pathophysiology, diagnostic issues, natural history/prognosis, and treatment. Written by experts in the field, Anemia in the Young and Old: Diagnosis and Management is a valuable resource for clinicians and practitioners who treat the pediatric and elderly patient population afflicted with anemia.
Author | : Sir John Vivian Dacie |
Publisher | : |
Total Pages | : 460 |
Release | : 1985 |
Genre | : Hemolytic anemia |
ISBN | : |
Author | : Isam Jaber Al-Zwaini |
Publisher | : BoD – Books on Demand |
Total Pages | : 140 |
Release | : 2018-07-11 |
Genre | : Medical |
ISBN | : 1789233666 |
Thalassemia is a very common disease first described by pediatrician Thomas Benton Cooley in 1925 who described it in a patient of Italian origin. At that time, it was designated as Cooley's anemia. George Hoyt Whipple, a Nobel prize winner, and W. L. Bradford, a professor of pediatrics at the University of Rochester, coined the term thalassemia in 1936, which in Greek means anemia of the sea (Thalassa means "sea", and emia means "blood"), due to the fact that it is very common in the area of the Mediterranean Sea. This name is actually misleading because it can occur everywhere in the world. Thalassemia is not a single disease; it is rather a group of hereditary disorders of the production of globulin chain of the hemoglobin. Throughout the world, thalassemia affects approximately 4.4 of every 10,000 live births. It represents a major social and emotional impact on the patient and his family and a major burden on health services where the prevalence is high.