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| Author | : Rolando Castro |
| Publisher | : |
| Total Pages | : 241 |
| Release | : 2017-11-06 |
| Genre | : |
| ISBN | : 9781973241270 |
Libro de texto para curso MECU 3031 (M�todos Cuantitativos) de la Universidad de Puerto Rico en Humacao.Repaso de �lgebra, aplicaciones de las ecuaciones, sistemas de ecuaciones, matem�ticas financieras
| Author | : Roger S. Pressman |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2019-09-09 |
| Genre | : Software engineering |
| ISBN | : 9781260548006 |
For almost four decades, Software Engineering: A Practitioner's Approach (SEPA) has been the world's leading textbook in software engineering. The ninth edition represents a major restructuring and update of previous editions, solidifying the book's position as the most comprehensive guide to this important subject.
| Author | : Sandeep Arora |
| Publisher | : CRC Press |
| Total Pages | : 342 |
| Release | : 2021-11-17 |
| Genre | : Medical |
| ISBN | : 100006493X |
This insightful volume opens new horizons for exploring modern therapeutic entities and emerging targets for combating the deadly disease of cancer. The authors provide a review of cancer along with descriptions of its molecular level mechanisms and emphasize the role of promising new therapies, including herbal therapies, that can be utilized for the treatment of metastatic diseases. The chapters look at specific approaches that have been researched and developed and that have almost reached the standardization stage, such as intracellular mechanisms, particularly phosphoprotein-enriched astrocytes and transthyretin proteins; CXCR4; autophagy-inhibiting drugs; spatiotemporal genetic analysis; tyrosine kinase inhibitors; and more. Also considered are advances in diagnostic systems like intra vital microscopy and molecular imaging.
| Author | : Clare Kelliher |
| Publisher | : Routledge |
| Total Pages | : 98 |
| Release | : 2019-04-26 |
| Genre | : Business & Economics |
| ISBN | : 1351128329 |
There is growing interest in flexible working, not only as a means to manage labour more efficiently and for greater agility, but also as a response to increasing concerns over well-being, work-life balance, and participation in the labour force of those with significant non-work commitments (e.g. parents, carers, older workers). As a result, a comprehensive stream of literature on the benefits and challenges of flexible working has developed and led to a body of evidence on the implementation and outcomes of different forms of flexible working arrangements. This book assesses the current state of this literature as follows: Background: the authors review the different definitions that have been proposed, policy developments, availability and uptake. Outcomes from flexible working: the main chapters focus on the outcomes for employers (e.g. performance, employee retention, organisational commitment etc.), as well as for individual employees (e.g. well-being, job satisfaction etc.). Evaluation of extant knowledge: the authors comment on the existing literature and consider the methodological approaches adopted in the literature. Conclusion: suggestions for future research are proposed. Of interest to students, academics and policy-makers, this book provides an expert overview of the empirical evidence and offers critical commentary on the state of knowledge in the field of flexible working and new forms of work.
| Author | : Lawrence Alderson |
| Publisher | : Shire Publications |
| Total Pages | : 40 |
| Release | : 2008-03-04 |
| Genre | : Technology & Engineering |
| ISBN | : 9780747805113 |
Breeds of livestock on British farms are changing constantly. New breeds emerge, foreign breeds are imported, while some native breeds lose popularity and become endangered. More than half the native breeds in Britain are rare and potentially threatened with extinction, yet they are an integral part of our history and heritage. Many of them are distinctive animals, and some possess special characteristics that could be of value to the livestock industry. A return to more traditional values was seen towards the end of the twentieth century, and this will serve to enhance the value of native breeds.
| Author | : Thomas N. Garavan |
| Publisher | : Springer Nature |
| Total Pages | : 194 |
| Release | : 2020-07-29 |
| Genre | : Business & Economics |
| ISBN | : 3030489000 |
This book offers an integrated and contextualised framework for learning and development (L&D) effectiveness that addresses both the nature of L&D and its antecedents and outcomes in organisations. Scholars and practitioners alike have recognised the important role that L&D plays in organisations, where the development of human capital is an essential component of individual employability, career advancement, organisational performance, and competitive advantage. The development of employees’ knowledge, skills, and attitudes constitutes one of the most important HR challenges that organisations face. The evidence indicates that organisations continue to invest in L&D programmes as part of their HR strategy. In addition, there has been an enormous growth in research on L&D in organisations; however, there is some ambiguity concerning the effectiveness of these activities and it largely remains unclear how they can be best implemented. This book seeks to address this gap in the literature. The authors propose a framework for L&D effectiveness based on key findings from reviews, empirical research, and meta-analyses, as well as previously established theoretical frameworks within the field. Combining theory and practice, the new framework this book offers provides key guidance for L&D practitioners and researches interested in the area.
| Author | : Jeremy M. Wilson |
| Publisher | : Rand Corporation |
| Total Pages | : 130 |
| Release | : 2010 |
| Genre | : Law |
| ISBN | : 9780833050175 |
Many police departments report difficulties in creating a workforce that represents community demographics, is committed to providing its employees the opportunity for long-term police careers, and effectively implements community policing. This book summarizes lessons on recruiting and retaining effective workforces.
| Author | : Edoardo Ales |
| Publisher | : Springer |
| Total Pages | : 302 |
| Release | : 2018-05-28 |
| Genre | : Business & Economics |
| ISBN | : 3319773291 |
Contributing to recent debate on the emergence of digital and agile work, this book explores the implications for labour and employment relations within and beyond organizational boundaries. Taking a multidisciplinary approach to the key issues and challenges of digitalization, this collection covers topics such as the gig economy, crowdworking and Industry 4.0. Theory and analysis are combined as the authors examine the impact of digital and smart work on organization, HRM and labour law. With comprehensive empirical evidence for those interested in understanding the more complex trajectories of today’s transforming work relationships, this book will not only appeal to students and academics but also to policy-makers, trade unionists and employers’ organizations.
| Author | : |
| Publisher | : |
| Total Pages | : 52 |
| Release | : 1993 |
| Genre | : Government publications |
| ISBN | : |
This document surveys the research on the effectiveness of 'high performance work practices'... [which] are designed to provide employees with skills, incentives, information, and decision-making responsibility that improve business performance and facilitate innovation.
| Author | : Fazlul H. Sarkar |
| Publisher | : Springer |
| Total Pages | : 0 |
| Release | : 2013-06-12 |
| Genre | : Medical |
| ISBN | : 9789400766112 |
Overall, this book illustrates the complexities of the regulation and deregulation of genes mediated through epigenetics in the development and progression of human malignancies. All the articles have been carefully chosen to represent several cancer systems with state of our knowledge on the role of epigenetic deregulation of microRNAs (miRNAs) and their target mRNAs along with epigenetic deregulation of mRNAs. This book also illustrates the role of several dietary agents, collectively called nutraceuticals or natural agents in modulating the epigenetic reprogramming of miRNAs and mRNAs for the prevention and/or treatment of human malignancies. It is well known that genetic aberrations, especially inherited through parents (somatic genetic alterations) contribute to the development of less than 10% of all cancer yet epigenetic alterations in genes especially through selective methylation and acetylation appears to be responsible for the development and progression of the vast majority of all cancers. Therefore, understanding the role of epigenetics in the regulation of genes especially through deregulated expression of miRNAs as presented in this book will allow scientists to devise targeted therapeutic strategies for re-expression of the lost genes or down-regulate the genes that are over-expressed in order to eradicate cancer. It is hoped that targeting epigenetics will not only target cancer cells but it will also target the tumor microenvironment (more like the entire tumor environment such as the entire host) for achieving better treatment outcomes for patients diagnosed with cancer which will lead to achieve the long-term objective for complete eradication of cancer. This book contains fifteen chapters which begins with the concept of systems and network biology for investigating the epigenetics of cancer followed by a series of articles on the role of miRNAs and their target genes in the biology of pancreatic cancer and other cancers such as breast, kidney, prostate and and colon. Since it is becoming increasingly clear that cancer stem cells (CSCs) are important in the development and progression of cancer, and CSCs are important in therapeutic resistance, treatment failure and tumor recurrence, thus the importance of CSCs and epigenetics has been highlighted by a very timely article on epigenetic variations of stem cell markers in cancer including miRNAs. Moreover, just targeting heterogeneous cancer cell populations may not be optimal to eradicate tumors and for which one must take a holistic approach for developing drugs that could also target the tumor microenvironment and tumor dormancy that are regulated through epigenetics. Keeping abreast with this thought process the concluding chapter provides a concept towards curative cancer therapy with maspin, which could be a unique window of opportunity to target tumor dormancy. Therefore, it suggest that targeting the tumor dormancy and the tumor microenvironment using novel therapeutics specifically by targeting epigenetics would become the future of medicine.
