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Handbook of Space Pharmaceuticals

Handbook of Space Pharmaceuticals
Author: Yashwant Pathak
Publisher: Springer
Total Pages: 0
Release: 2022-05-08
Genre: Medical
ISBN: 9783030055271

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This two-volume handbook, directed at medical professionals and students who are involved in developing the space industry or are academicians doing research in this area, covers current pharmaceutical knowledge about the difference in medication efficacy in space versus on Earth and includes trial results and best practices for the space research and travel industry. The well-known contributors come from an interdisciplinary background and address all aspects of the subject, from the physiological impact of spaceflight to the effects of radiation. As the commercial space industry expands its operations in industry and tourism, the field of space pharmaceuticals is growing commensurately. Existing pharmacological research from space is thoroughly covered in this book, and Earth applications are also described. Potential pharmacological solutions are posed along with the known challenges and examples from existing studies, which are detailed at length. This major reference work is a comprehensive and important medical resource for all space industry players.


Space Pharmacology

Space Pharmacology
Author: Virginia E. Wotring
Publisher: Springer Science & Business Media
Total Pages: 119
Release: 2012-03-18
Genre: Science
ISBN: 1461433959

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“Space Pharmacology” is a review of the current knowledge regarding the use of pharmaceuticals during spaceflights. It is a comprehensive review of the literature, addressing each area of pharmacokinetics and each major physiological system in turn. Every section begins with a topic overview, and is followed by a discussion of published data from spaceflight, and from ground experiments meant to model the spaceflight situation. Includes a discussion looking forward to the new medical challenges we are likely to face on longer duration exploration missions. This book is a snapshot of our current knowledge that also highlights areas of unknown.


Handbook of Modern Pharmaceutical Analysis

Handbook of Modern Pharmaceutical Analysis
Author: Satinder Ahuja
Publisher: Academic Press
Total Pages: 604
Release: 2010-11-11
Genre: Medical
ISBN: 0123759811

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Handbook of Modern Pharmaceutical Analysis, Second Edition, synthesizes the complex research and recent changes in the field, while covering the techniques and technology required for today's laboratories. The work integrates strategy, case studies, methodologies, and implications of new regulatory structures, providing complete coverage of quality assurance from the point of discovery to the point of use. Treats pharmaceutical analysis (PA) as an integral partner to the drug development process rather than as a service to it Covers method development, validation, selection, testing, modeling, and simulation studies combined with advanced exploration of assays, impurity testing, biomolecules, and chiral separations Features detailed coverage of QA, ethics, and regulatory guidance (quality by design, good manufacturing practice), as well as high-tech methodologies and technologies from "lab-on-a-chip" to LC-MS, LC-NMR, and LC-NMR-MS


Handbook of Pharmaceutical Wet Granulation

Handbook of Pharmaceutical Wet Granulation
Author: Ajit S. Narang
Publisher: Academic Press
Total Pages: 890
Release: 2018-08-31
Genre: Medical
ISBN: 0323481035

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Handbook of Pharmaceutical Wet Granulation: Theory and Practice in a Quality by Design Paradigm offers a single and comprehensive reference dedicated to all aspects of pharmaceutical wet granulation, taking a holistic approach by combining introductory principles with practical solutions. Chapters are written by international experts across industry, academic and regulatory settings, and cover a wide spectrum of relevant and contemporary wet granulation topics, techniques and processes. The books' focus on process analytical technology, quality by design principles, granulation equipment, modeling, scale-up, control and real time release makes it a timely and valuable resource for all those involved in pharmaceutical wet granulation. Discusses fundamentals of theory and current industrial practice in the field of wet granulation, including product and process design and role of material properties in wet granulation Examines the modern evolution of wet granulation through current topics such as established and novel process analytical technologies (PATs), and product development and scale-up paradigms Written for scientists working within the pharmaceutical industry, as well as academics, regulatory officials and equipment vendors who provide PAT tools and granulation equipment


Handbook of Polyester Drug Delivery Systems

Handbook of Polyester Drug Delivery Systems
Author: M. N. V. Ravi Kumar
Publisher: CRC Press
Total Pages: 401
Release: 2017-03-27
Genre: Medical
ISBN: 1315341166

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In the quest for innovative drug delivery systems attempting to meet the unmet needs in pharmaceutical space, research has taken a much more complicated path that poses a significant challenge for translation. Despite the progress made with novel materials, polyesters still remain at the helm of drug delivery technologies. This book provides a single source of reference of polyester drug delivery systems that covers a broad spectrum of materials design, manufacturing techniques, and applications.


Handbook of Pharmaceutical Analysis by HPLC

Handbook of Pharmaceutical Analysis by HPLC
Author: Satinder Ahuja
Publisher: Elsevier
Total Pages: 679
Release: 2005-02-09
Genre: Medical
ISBN: 0080455182

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High pressure liquid chromatography–frequently called high performance liquid chromatography (HPLC or, LC) is the premier analytical technique in pharmaceutical analysis and is predominantly used in the pharmaceutical industry. Written by selected experts in their respective fields, the Handbook of Pharmaceutical Analysis by HPLC Volume 6, provides a complete yet concise reference guide for utilizing the versatility of HPLC in drug development and quality control. Highlighting novel approaches in HPLC and the latest developments in hyphenated techniques, the book captures the essence of major pharmaceutical applications (assays, stability testing, impurity testing, dissolution testing, cleaning validation, high-throughput screening). A complete reference guide to HPLC Describes best practices in HPLC and offers 'tricks of the trade' in HPLC operation and method development Reviews key HPLC pharmaceutical applications and highlights currents trends in HPLC ancillary techniques, sample preparations, and data handling


Handbook of Drug Screening

Handbook of Drug Screening
Author: Ramakrishna Seethala
Publisher: CRC Press
Total Pages: 619
Release: 2001-07-24
Genre: Medical
ISBN: 0824741447

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A presentation of screening techniques, modern technologies, and high-capacity instrumentation for increased productivity in the development and discovery of new drugs, chemical compounds, and targeted delivery of pharmaceuticals. It contains practical applications and examples of strategies in cell-based and cell-free screens as well as homogeneous, fluorescence, chemiluminescence, and radioactive-based technologies.


Handbook of Isolation and Characterization of Impurities in Pharmaceuticals

Handbook of Isolation and Characterization of Impurities in Pharmaceuticals
Author: Satinder Ahuja
Publisher: Elsevier
Total Pages: 432
Release: 2003-06-26
Genre: Medical
ISBN: 008050776X

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The United States Food and Drug Administration (FDA) and other regulatory bodies around the world require that impurities in drug substance and drug product levels recommended by the International Conference on Harmonisation (ICH) be isolated and characterized. Identifying process-related impurities and degradation products also helps us to understand the production of impurities and assists in defining degradation mechanisms. When this process is performed at an early stage, there is ample time to address various aspects of drug development to prevent or control the production of impurities and degradation products well before the regulatory filing and thus assure production of a high-quality drug product.This book, therefore, has been designed to meet the need for a reference text on the complex process of isolation and characterization of process-related (synthesis and formulation) impurities and degradation products to meet critical requlatory requirements.It's objective is to provide guidance on isolating and characterizing impurities of pharmaceuticals such as drug candidates, drug substances, and drug products. The book outlines impurity identification processes and will be a key resource document for impurity analysis, isolation/synthesis, and characterization. - Provides valuable information on isolation and characterization of impurities. - Gives a regulatory perspective on the subject. - Describes various considerations involved in meeting regulatory requirements. - Discusses various sources of impurities and degredation products.


In-Space Manufacturing and Resources

In-Space Manufacturing and Resources
Author: Volker Hessel
Publisher: John Wiley & Sons
Total Pages: 436
Release: 2022-07-04
Genre: Technology & Engineering
ISBN: 352783091X

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Comprehensive resource covering all in-space manufacturing and planetary resource exploration endeavors. The space economy is developing quickly, and pivotal events have brought us to a strong inflection point. This unique book includes fundamental and ground-breaking innovations in the field and is meant to quickly get readers up to speed on many different facets of space and planetary resource exploration, such as: Space health & medicine Space biology & space farming Space chemistry & space mining Space construction & advanced materials production Space policy, law & economics Presenting a snapshot of the expanding space economy and manufacturing applications in low-Earth orbit, along with resource utilization capabilities in development for Moon and Mars missions, this an indispensable source for all researchers and commercial companies working on space and planetary resource exploration.