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Guidance Document on Application and Interpretation of Single-species Tests in Environmental Toxicology, EPS 1/RM/34, December 1999

Guidance Document on Application and Interpretation of Single-species Tests in Environmental Toxicology, EPS 1/RM/34, December 1999
Author:
Publisher:
Total Pages:
Release: 2000
Genre:
ISBN:

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This book is to provide guidance on using and interpreting single-species toxicity tests for protecting the environment. It focuses on the toxicity tests published by Environment Canada, and supplements the other documents of that department, which deal with sampling, testing, analyses. Aquatic tests receive most emphasis because they are in more frequent use, but tests with sediments and soil also receive coverage. Both lethal and sublethal tests are included.


Guidance Document on Control of Toxicity Test Precision Using Reference Toxicants

Guidance Document on Control of Toxicity Test Precision Using Reference Toxicants
Author: Canada. Environmental Protection Service
Publisher: Environment Canada
Total Pages: 104
Release: 1990
Genre: Aquatic biology
ISBN:

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A reference toxicant is a chemical used in toxicity tests to provide results that can be compared within a laboratory or among laboratories. This report describes the use of reference toxicants within a laboratory for control of toxicity test precision over time. Thirteen chemicals were evaluated for their suitability as reference toxicants. Procedures for chemical acquisition, safe handling and storage are presented and instructions are provided for establishing and interpreting control charts, as well as reporting data. Monitoring and interpreting duplicate test data are also discussed.


Guidance Document for Testing the Pathogenicity and Toxicity of New Microbial Substances to Aquatic and Terrestrial Organisms

Guidance Document for Testing the Pathogenicity and Toxicity of New Microbial Substances to Aquatic and Terrestrial Organisms
Author:
Publisher:
Total Pages: 0
Release: 2017
Genre: Biological assay
ISBN: 9780660070889

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The intent of this document is to provide guidance on preparing for and conducting single-species tests to measure and evaluate the pathogenicity and/or toxicity of new microbial substances to aquatic and terrestrial organisms. It focuses on the information requirements with respect to laboratory tests for measuring the potential ecological effects of new microbial substances on the following six categories of test (host) organisms, that might be required by Environment Canada as part of the New Substances Notification (NSN) Regulations under the Canadian Environmental Protection Act, 1999: (1) an aquatic plant; (2) an aquatic invertebrate; (3) an aquatic vertebrate; (4) a terrestrial plant; (5) a terrestrial invertebrate; and (6) a terrestrial vertebrate. The guidance herein is intended for notifiers, environmental consultants, study directors, and principal investigators. It will assist in the selection of an appropriate series of biological test methods for measuring the pathogenicity and/or toxicity of new microbial substances, as well as in the planning, execution, and reporting phases associated with each test.


Toxicity Testing for Assessment of Environmental Agents

Toxicity Testing for Assessment of Environmental Agents
Author: National Research Council
Publisher: National Academies Press
Total Pages: 270
Release: 2006-04-07
Genre: Nature
ISBN: 0309164869

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Toxicity testing in laboratory animals provides much of the information used by the Environmental Protection Agency (EPA) to assess the hazards and risks associated with exposure to environmental agents that might harm public health or the environment. The data are used to establish maximum acceptable concentrations of environmental agents in drinking water, set permissible limits of exposure of workers, define labeling requirements, establish tolerances for pesticides residues on food, and set other kinds of limits on the basis of risk assessment. Because the number of regulations that require toxicity testing is growing, EPA called for a comprehensive review of established and emerging toxicity-testing methods and strategies. This interim report reviews current toxicity-testing methods and strategies and near-term improvements in toxicity-testing approaches proposed by EPA and others. It identifies several recurring themes and questions in the various reports reviewed. The final report will present a long-range vision and strategic plan to advance the practices of toxicity testing and human health assessment of environmental contaminants.


Introduction to Environmental Toxicology

Introduction to Environmental Toxicology
Author: Wayne Landis
Publisher: CRC Press
Total Pages: 536
Release: 2010-12-16
Genre: Science
ISBN: 1439804109

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After fifteen years and three editions, Introduction to Environmental Toxicology: Molecular Substructures to Ecological Landscapes has become a standard that defines the field of environmental toxicology, and the fourth edition is no exception. The authors take an integrated approach to environmental toxicology that emphasizes scale and context as important factors in understanding effects and management options. New in the Fourth Edition: New author, Dr. Ruth M. Sofield 8-page color insert New chapter on fate and transport of contaminants Emphasis on the use of all types of models in understanding how nature works Revised sections on synergy and atrazine toxicity Updated coverage of the analysis of impacts to populations, communities and ecosystems Enlarged risk assessment chapter with an in-depth description of a regional scale risk assessment This edition benefits from the insight of a new author, Dr. Ruth M. Sofield, who prepared the new chapter on the fate and transport of contaminants. The relationship between structure and toxicological properties has been a major theme of this book since its inception and this new chapter expands this fundamental concept to include fate and transport. In the early chapters the use of models in science is discussed and this theme carries throughout the rest of the book. So much has changed in the fifteen years since the publication of the first edition. The mid-1990s seem so long ago, when our understanding of environmental toxicology was very basic. Ecological risk assessment was in its very early stages and the consideration of the effects of toxicants on landscapes was only beginning. Computation was still hard, genes stayed put, and it was only becoming recognized that xenobiotics could have hormonal effects — developments that are taken for granted in this edition. Written by authors who teach this subject, a feature that is reflected in their straightforward style, the book provides a foundation for understanding environmental toxicology and its application.


Small-scale Freshwater Toxicity Investigations

Small-scale Freshwater Toxicity Investigations
Author: Christian Blaise
Publisher: Springer Science & Business Media
Total Pages: 563
Release: 2006-01-16
Genre: Science
ISBN: 1402031203

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This broad review is the first to gather comprehensive information on the complete contemporary range of toxicity testing procedures and hazard assessment procedures, which is normally scattered and difficult to find. The two-volume set provides a consistent, template-based approach, linking relevant information on background, theory and practice to each bioassay. Volume 1 covers small-scale toxicity test methods. Includes extensive glossary.