Glycosylation And Cancer PDF Download
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Author | : Ajit Varki |
Publisher | : CSHL Press |
Total Pages | : 694 |
Release | : 1999 |
Genre | : Medical |
ISBN | : 9780879696818 |
Download Essentials of Glycobiology Book in PDF, ePub and Kindle
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Author | : Ajit Varki |
Publisher | : |
Total Pages | : 680 |
Release | : 1999 |
Genre | : Medical |
ISBN | : |
Download Essentials of Glycobiology Book in PDF, ePub and Kindle
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Author | : Ajit Varki |
Publisher | : |
Total Pages | : 653 |
Release | : 1999-01-01 |
Genre | : Science |
ISBN | : 9780879695606 |
Download Essentials of Glycobiology Book in PDF, ePub and Kindle
Glycobiology has its roots in the nineteenth century, when chemists first began to analyze sugar and polysaccharides. Advances in this area continued at a steady rate during most of this century, but the past 20 years has witnessed an unparalleled explosion of new knowledge that has transformed the field. This monograph contains the basic information needed to understand the field of glycobiology along with the most current work at the forefront of the field.
Author | : |
Publisher | : Academic Press |
Total Pages | : 418 |
Release | : 2015-02-26 |
Genre | : Science |
ISBN | : 0128016140 |
Download Glycosylation and Cancer Book in PDF, ePub and Kindle
Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. Provides information on cancer research Outstanding and original reviews Suitable for researchers and students
Author | : Minoru Fukuda |
Publisher | : CRC Press |
Total Pages | : 342 |
Release | : 1991-12-13 |
Genre | : Science |
ISBN | : 9780849364358 |
Download Cell Surface Carbohydrates and Cell Development Book in PDF, ePub and Kindle
Cell Surface Carbohydrates and Cell Development summarizes knowledge on the structure and function of cell surface carbohydrates in development and differentiation. The chapters include reviews on the expression of cell type-specific carbohydrates and their roles in cell-cell interaction. In particular, the role of cell surface carbohydrates in immune cell response, malignant transformation, fertilization, and neural cell development are addressed. This includes the exciting discovery about the role of adhesive molecules in leukocyte-endothellium interaction. Cell Surface Carbohydrates and Cell Development also summarizes the latest knowledge on structure and biosynthesis of carbohydrates, the role of specific carbohydrate modification, and animal lectins. The book will be useful to researchers and students interested in the biology of glycoproteins and biotechnology.
Author | : Marija Pezer |
Publisher | : Springer Nature |
Total Pages | : 588 |
Release | : 2021-10-22 |
Genre | : Medical |
ISBN | : 3030769127 |
Download Antibody Glycosylation Book in PDF, ePub and Kindle
This book summarizes recent advances in antibody glycosylation research. Covering major topics relevant for immunoglobulin glycosylation - analytical methods, biosynthesis and regulation, modulation of effector functions - it provides new perspectives for research and development in the field of therapeutic antibodies, biomarkers, vaccinations, and immunotherapy. Glycans attached to both variable and constant regions of antibodies are known to affect the antibody conformation, stability, and effector functions. Although it focuses on immunoglobulin G (IgG), the most explored antibody in this context, and unravels the natural phenomena resulting from the mixture of IgG glycovariants present in the human body, the book also discusses other classes of human immunoglobulins, as well as immunoglobulins produced in other species and production systems. Further, it reviews the glycoanalytical methods applied to antibodies and addresses a range of less commonly explored topics, such as automatization and bioinformatics aspects of high-throughput antibody glycosylation analysis. Lastly, the book highlights application areas ranging from the ones already benefitting from antibody glycoengineering (such as monoclonal antibody production), to those still in the research stages (such as exploration of antibody glycosylation as a clinical or biological age biomarker), and the potential use of antibody glycosylation in the optimization of vaccine production and immunization protocols. Summarizing the current knowledge on the broad topic of antibody glycosylation and its therapeutic and biomarker potential, this book will appeal to a wide biomedical readership in academia and industry alike. Chapter 4 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Author | : Koichi Furukawa |
Publisher | : Springer |
Total Pages | : 219 |
Release | : 2016-01-26 |
Genre | : Science |
ISBN | : 4431559396 |
Download Glycosignals in Cancer: Mechanisms of Malignant Phenotypes Book in PDF, ePub and Kindle
This book is a collection of cutting-edge studies on the functions and mechanisms of glycosylation in cancers. Along with progress in genomics and proteomics, new findings in the significance of these complex carbohydrates, through the regulation of cell signals, have been elucidated in a wide variety of biological events. This volume provides a comprehensive summary of glycosignals and their involvement in cancer, covering numerous topics such as glycosylation machineries, regulation of phenotypes, cell signaling, immune regulation, complex carbohydrate organization, and clinical applications. The contents have been organized to promote ready understanding, covering basic to clinical research and studies on micromolecules, to animal/human cells and tissues. This book is an essential read for students and young researchers interested in cancers and carbohydrates. Specialists in glycobiology will also benefit from the new results and approaches detailed here, which provide insights into future directions of functional studies of sugar chains in both basic and applied research.
Author | : John R. Griffiths |
Publisher | : John Wiley & Sons |
Total Pages | : 414 |
Release | : 2016-11-07 |
Genre | : Science |
ISBN | : 1119045851 |
Download Analysis of Protein Post-Translational Modifications by Mass Spectrometry Book in PDF, ePub and Kindle
Covers all major modifications, including phosphorylation, glycosylation, acetylation, ubiquitination, sulfonation and and glycation Discussion of the chemistry behind each modification, along with key methods and references Contributions from some of the leading researchers in the field A valuable reference source for all laboratories undertaking proteomics, mass spectrometry and post-translational modification research
Author | : Naoyuki Taniguchi |
Publisher | : Springer Science & Business Media |
Total Pages | : 668 |
Release | : 2011-06-28 |
Genre | : Science |
ISBN | : 4431678778 |
Download Handbook of Glycosyltransferases and Related Genes Book in PDF, ePub and Kindle
The so-called postgenomic research era has now been launched, and the field of gly cobiology and glycotechnology has become one of the most important areas in life science because glycosylation is the most common post-translational modification reaction of proteins in vivo. On the basis of Swiss-Prot data, over 50% proteins are known to undergo glycosylation, but in fact the actual functions of most of the sugar chains in the glycoconjugates remain unknown. The complex carbohydrate chains of glycoproteins, glycolipids, and proteoglycans represent the secondary gene products formed through the reactions of glycosyl transferases. The regulation of the biosynthesis of sugar chains is under the control of the expression of glycosyltransferases, their substrate specificity, and their local ization in specific tissue sites. There is a growing body of evidence to suggest that these enzymes play pivotal roles in a variety of important cellular differentiation and developmental events, as well as in disease processes. Over 300 glycosyltransferases appear to exist in mammalian tissues. If the genes that have been purified and cloned from various species such as humans, cattle, pigs, rats and mice are counted as one, approximately 110 glycogenes that encode glycosyltransferases and related genes have been cloned at present, and this number continues to grow each day. However, most of the functions of the glycosyltransferase genes and related genes are unknown. This fact has stimulated numerous new and interesting approaches in molecular biologi cal investigations.
Author | : Joëlle Roche |
Publisher | : MDPI |
Total Pages | : 261 |
Release | : 2018-04-09 |
Genre | : Electronic book |
ISBN | : 3038427934 |
Download The Epithelial-to-Mesenchymal Transition (EMT) in Cancer Book in PDF, ePub and Kindle
This book is a printed edition of the Special Issue "The Epithelial-to-Mesenchymal Transition (EMT) in Cancer" that was published in Cancers