Glycopolymers Polyelectrolyte Multilayers For Biomedical Applications PDF Download
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Author | : |
Publisher | : Scholar Press |
Total Pages | : 268 |
Release | : 2018-01-16 |
Genre | : |
ISBN | : 6202306238 |
Download Glycopolymers Polyelectrolyte Multilayers for Biomedical Applications Book in PDF, ePub and Kindle
The theoretical background of this work is concerning with the drug loaded polyelectrolyte multilayers (PEM) modified by the host-guest interaction of biocompatible hyperbranched core-shell glycopolymers. The glycopolymer in this work is the hyperbranched polyethyleneimine that was modified with maltose moieties using reductive amination. Thus, the use of glycohyperbranched polymers for drug delivery would allow the avoid naturally occurring drug resistance due to decreased transporter activity. Concerning preparative method, PEM was fabricated using layer-by-layer (LbL) processes involve the sequential deposition of two polyions that physically bond together. Control was taken on the stoichiometric ratio related to cationic and anionic repeating units, which was chosen close to zero for the final applied PEM. Concerning analytical methods, a couple of physical-chemical methods were applied to characterize colloid stability, adhesiveness, drug loading and release of fabricated PEM. In conclusion, a highly sable and sustainable PEM coats on a surface of an activated solid substrate has been fabricated with an efficient ability to recycle the charged molecule for more than 24 times.
Author | : Samaa Ragab Ali Ragab Salem |
Publisher | : |
Total Pages | : 0 |
Release | : 2015 |
Genre | : |
ISBN | : |
Download Glycopolymer Polyelectrolyte Multilayers Based on Maltose-modified Hyperbranched Poly(ethyleneimine) for Future Drug Delivery Coatings and Biomedical Applications Book in PDF, ePub and Kindle
Author | : Sukant K. Tripathy |
Publisher | : |
Total Pages | : 384 |
Release | : 2002 |
Genre | : Polyelectrolytes |
ISBN | : |
Download Handbook of Polyelectrolytes and Their Applications: Polyelectrolyte-based multilayers, self-assemblies and nanostructures Book in PDF, ePub and Kindle
Author | : Sukant K. Tripathy |
Publisher | : |
Total Pages | : 378 |
Release | : 2002 |
Genre | : Polyelectrolytes |
ISBN | : |
Download Handbook of Polyelectrolytes and Their Applications: Applications of polyelectrolytes and theoretical models Book in PDF, ePub and Kindle
Author | : Ravin Narain |
Publisher | : John Wiley & Sons |
Total Pages | : 416 |
Release | : 2011-03-01 |
Genre | : Technology & Engineering |
ISBN | : 1118002245 |
Download Engineered Carbohydrate-Based Materials for Biomedical Applications Book in PDF, ePub and Kindle
This book addresses the need for a comprehensive book on the design, synthesis, and characterization of synthetic carbohydrate-based polymeric materials along with their biological applications. The first two chapters cover the synthesis and self-assembly of glycopolymers and different techniques for creating these synthetic polymers. Subsequent chapters account for the preparation of block copolymers, branched glycopolymers, glycosurfaces, glycodendrimers, cationic glycopolymers, bioconjugates, glyconanoparticles and hydrogels. While these chapters comprehensively review the synthetic and characterization methods of those carbohydrate-based materials, their biological applications are discussed in detail.
Author | : Anne Palermo |
Publisher | : |
Total Pages | : 192 |
Release | : 2012 |
Genre | : |
ISBN | : |
Download Polyelectrolyte Multilayer Complexes Book in PDF, ePub and Kindle
Author | : Solar Candido Ademola Olugebefola |
Publisher | : |
Total Pages | : 155 |
Release | : 2007 |
Genre | : |
ISBN | : |
Download Polyelectrolyte Multilayers Incorporating Photocrosslinking Polymers for Controlling 2- and 3-dimensional Structure Book in PDF, ePub and Kindle
Polyelectrolyte multilayer (PEM) assembly is a technology for building thin films with a number of useful and novel functionalities. PEMs interact favorably with proteins and other biomolecules making them potentially valuable as biomaterials. Many systems of polymers have been studied for use in PEMs, including weak polyelectrolytes such as those containing poly(acrylic acid) (PAA) and poly(allyamine hydrochloride) (PAH), which exhibit pH-dependent behavior. Properties such as thickness, swellability, mechanical stiffness, porosity (and by extention optical properties), and ability to adsorb small molecules are all controlled by the charge density of these polymers in the film and their resultant binding state. Patterning covalent binding through photo-crosslinking in addition to electrostatic binding, can locally override the native tendency to change structure with changes in pH. To achieve this, poly(acrylic acid) was chemically modified through a halide esterification reaction to incorporate photo-crosslinkable vinylbenzyl side groups, making poly(acrylic acid-ran-vinylbenzyl acrylate) (PAArVBA). The chemical modification was characterized by nuclear magnetic resonance spectroscopy (NMR) and light spectroscopy.
Author | : Phuong Nguyen Tri |
Publisher | : Elsevier |
Total Pages | : 558 |
Release | : 2019-11-08 |
Genre | : Technology & Engineering |
ISBN | : 0128168919 |
Download Smart Nanocontainers Book in PDF, ePub and Kindle
Smart Nanocontainers explores the fundamental concepts and emerging applications of nanocontainers in biomedicine, pharmaceuticals and smart materials. In pharmaceuticals, nanocontainers have advantages over their micro-counterparts, including more efficient drug detoxification, higher intracellular uptake, better stability, less side effects and higher biocompatibility with tissue and cells. In materials science, such as coating technology, they help by making coatings smarter, stronger and more durable. This important reference will help anyone who wants to learn more on how nanocontainers are used to provide the controlled release of active agents, including their applications in smart coatings, corrosion, drug delivery, diagnosis, agri-food and gas storage. Discusses how the molecular design of nanocarriers can be optimized to increase performance Explores how nanocarriers are being used to produce a new generation of active coatings Explains how nanocarriers are being used to deliver more effective nanoscale drug delivery
Author | : |
Publisher | : John Wiley & Sons |
Total Pages | : 453 |
Release | : 2010-03-08 |
Genre | : Technology & Engineering |
ISBN | : 3527321551 |
Download Nanostructured Thin Films and Surfaces Book in PDF, ePub and Kindle
The book series Nanomaterials for the Life Sciences, provides an in-depth overview of all nanomaterial types and their uses in the life sciences. Each volume is dedicated to a specific material class and covers fundamentals, synthesis and characterization strategies, structure-property relationships and biomedical applications. The series brings nanomaterials to the Life Scientists and life science to the Materials Scientists so that synergies are seen and developed to the fullest. Written by international experts of various facets of this exciting field of research, the series is aimed at scientists of the following disciplines: biology, chemistry, materials science, physics, bioengineering, and medicine, together with cell biology, biomedical engineering, pharmaceutical chemistry, and toxicology, both in academia and fundamental research as well as in pharmaceutical companies. VOLUME 5 - Nanostructured Thin Films and Surfaces
Author | : Andreas Taubert |
Publisher | : John Wiley & Sons |
Total Pages | : 616 |
Release | : 2013-07-12 |
Genre | : Science |
ISBN | : 3527649638 |
Download Biomaterials Surface Science Book in PDF, ePub and Kindle
At the interface of biology, chemistry, and materials science, this book provides an overview of this vibrant research field, treating the seemingly distinct disciplines in a unified way by adopting the common viewpoint of surface science. The editors, themselves prolific researchers, have assembled here a team of top-notch international scientists who read like a "who's who" of biomaterials science and engineering. They cover topics ranging from micro- and nanostructuring for imparting functionality in a top-down manner to the bottom-up fabrication of gradient surfaces by self-assembly, from interfaces between biomaterials and living matter to smart, stimuli-responsive surfaces, and from cell and surface mechanics to the elucidation of cell-chip interactions in biomedical devices. As a result, the book explains the complex interplay of cell behavior and the physics and materials science of artificial devices. Of equal interest to young, ambitious scientists as well as to experienced researchers.