Glucose Metabolism In The Brain PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Glucose Metabolism In The Brain PDF full book. Access full book title Glucose Metabolism In The Brain.
Author | : |
Publisher | : Elsevier |
Total Pages | : 570 |
Release | : 2002-11-04 |
Genre | : Medical |
ISBN | : 0080491596 |
Download Glucose Metabolism in the Brain Book in PDF, ePub and Kindle
Regulation of glucose at the biochemical level affects every area of the brain, and has impact from cellular to behavioral brain function. It plays an important role in diseases such as diabetes, stroke, schizophrenia and drug abuse as well as in normal and dysfunctional memory and cognition. This volume represents a thorough examination of all the major issues that are relevant to glucose metabolism by brain cells in relation to disease, combining basic research and clinical findings in a single, indispensable reference. Serves as an essential reference on glucose metabolism in the brain Presents authoritative accounts by leading researchers in the field Includes thorough reviews with provocative sections on future directions
Author | : Donard S.. Dwyer |
Publisher | : |
Total Pages | : 0 |
Release | : 2002 |
Genre | : |
ISBN | : |
Download Glucose Metabolism in the Brain Book in PDF, ePub and Kindle
Author | : Chris D. Geddes |
Publisher | : Springer Science & Business Media |
Total Pages | : 460 |
Release | : 2007-12-29 |
Genre | : Science |
ISBN | : 0387330151 |
Download Glucose Sensing Book in PDF, ePub and Kindle
An essential reference for any laboratory working in the analytical fluorescence glucose sensing field. The increasing importance of these techniques is typified in one emerging area by developing non-invasive and continuous approaches for physiological glucose monitoring. This volume incorporates analytical fluorescence-based glucose sensing reviews, specialized enough to be attractive to professional researchers, yet appealing to a wider audience of scientists in related disciplines of fluorescence.
Author | : Johannes Hirrlinger |
Publisher | : Humana Press |
Total Pages | : 0 |
Release | : 2014-09-16 |
Genre | : Medical |
ISBN | : 9781493910588 |
Download Brain Energy Metabolism Book in PDF, ePub and Kindle
Brain Energy Metabolism addresses its challenging subject by presenting diverse technologies allowing for the investigation of brain energy metabolism on different levels of complexity. Model systems are discussed, starting from the reductionist approach like primary cell cultures which allow assessing of the properties and functions of a single brain cell type with many different types of analysis, however, at the expense of neglecting the interaction between cell types in the brain. On the other end, analysis in animals and humans in vivo is discussed, maintaining the full complexity of the tissue and the organism but making high demands on the methods of analysis. Written for the popular Neuromethods series, chapters include the kind of detailed description and key implementation advice that aims to support reproducible results in the lab. Meticulous and authoritative, Brain Energy Metabolism provides an ideal guide for researchers interested in brain energy metabolism with the hope of stimulating more research in this exciting and very important field.
Author | : David Bihari |
Publisher | : Springer Science & Business Media |
Total Pages | : 449 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 3642839290 |
Download Brain Failure Book in PDF, ePub and Kindle
This book proves essential to understanding the problem of brain failure by emphasizing the various therapeutic approaches which have previously been somewhat neglected. The book summarizes the mechanisms involved in the pathogenesis of the various forms of brain failure, examining in detail structural and examining metabolic causes. Special consideration has been given to patients with severe head trauma, stroke, subarachnoid haemorrhage and to a variety of metabolic causes of coma. The relationship between cerebral blood flow and cerebral metabolic rate is explored, providing important conclusions with regard to therapy. New techniques of monitoring brain failure are described and their clinical usefulness defined, providing intensive care physicians, anaesthesiologists and neurologists a solid basis on which to build their knowledge of the brain-failure patient.
Author | : Laszlo Zaborszky |
Publisher | : Springer Science & Business Media |
Total Pages | : 429 |
Release | : 2013-03-09 |
Genre | : Medical |
ISBN | : 1475720556 |
Download Neuroanatomical Tract-Tracing Methods 2 Book in PDF, ePub and Kindle
This new edition presents readers with the latest information on neuroscience. This book explores the advances in molecular techniques, genomics and proteomics and the progress in fluorescence.
Author | : Fei Yin |
Publisher | : Frontiers Media SA |
Total Pages | : 161 |
Release | : 2017-08-16 |
Genre | : |
ISBN | : 2889452530 |
Download The Metabolic-Inflammatory Axis in Brain Aging and Neurodegeneration Book in PDF, ePub and Kindle
Impairment of energy metabolism is a hallmark of brain aging and several neurodegenerative diseases, such as the Alzheimer’s disease (AD). Age- and disease-related hypometabolism is commonly associated with oxidative stress and they are both regarded as major contributors to the decline in synaptic plasticity and cognition. Neuroinflammatory changes, entailing microglial activation and elevated expression of inflammatory cytokines, also correlate with age-related cognitive decline. It is still under debate whether the mitochondrial dysfunction-induced metabolic deficits or the microglia activation-mediated neuroinflammation is the initiator of the cognitive changes in aging and AD. Nevertheless, multiple lines of evidence support the notion that mitochondrial dysfunction and chronic inflammation exacerbate each other, and these mechanistic diversities have cellular redox dysregulation as a common denominator. This research topic focuses on the role of a metabolic-inflammatory axis encompassing the bioenergetic activity, brain inflammatory responses and their redox regulation in healthy brain aging and neurodegenerative diseases. Dynamic interactions among these systems are reviewed in terms of their causative or in-tandem occurrence and how the systemic environment, –e.g., insulin resistance, diabetes, and systemic inflammation–, impacts on brain function.
Author | : |
Publisher | : Elsevier |
Total Pages | : 447 |
Release | : 1972-01-01 |
Genre | : Medical |
ISBN | : 0080861601 |
Download Cerebral Blood Flow Book in PDF, ePub and Kindle
Progress in Brain Research is the most acclaimed and accomplished series in neuroscience. The serial is well-established as an extensive documentation of contemporary advances in the field. The volumes contain authoritative reviews and original articles by invited specialists. The rigorous editing of the volumes assures that they will appeal to all laboratory and clinical brain research workers in the various disciplines: neuroanatomy, neurophysiology, neuropharmacology, neuroendocrinology, neuropathology, basic neurology, biological psychiatry and the behavioral sciences.
Author | : Alan A. Boulton |
Publisher | : Humana |
Total Pages | : 383 |
Release | : 2013-08-14 |
Genre | : Medical |
ISBN | : 9781489941039 |
Download Carbohydrates and Energy Metabolism Book in PDF, ePub and Kindle
The mammalian central nervous system depends almost - clusively on glucose as its major energy source. In addition, g- cose participates in other cerebral metabolic functions including the biosynthesis of neurotransmitters, such as acetylcholine and the amino acids. This volume of Neuromethods assembles currently available methods for the study of cerebral glucose and energy metabolism in vitro and in mm. In the first chapter, Lust et al. describe the various methods available for the appropriate fixation of brain tissue necessary for the study of cerebral energy metabolism. Different fixation methods are compared, and some concerns raised by the USDHHS in their guidelines for the care and use of laboratory animals are addressed. Specific fixation methods pertinent to the various measurements are also covered in other chapters. In vitro p- parations have, despite certain limitations, been found to be useful in the study of brain metabolism, since the biochemical envir- ment is amenable to rapid, controlled manipulation. The chapter by Lai and Clark describes methods for the isolation and characterization of metabolically active preparations of synaptic and non-synaptic mitochondria from brain, and studies of - zymes involved in glucose metabolism and glucose-derived neurotransmitter synthesis in these preparations are summarized. The chapter by Whittingham discusses methods of preparations of hippocampal slices for use in the study of energy metabolism. Measurement of glucose and of glycolytic and dicarboxylic acid cycle intermediates in neural tissues are described in the chapter by Bachelard.
Author | : Anne Le |
Publisher | : Springer |
Total Pages | : 186 |
Release | : 2018-06-26 |
Genre | : Medical |
ISBN | : 331977736X |
Download The Heterogeneity of Cancer Metabolism Book in PDF, ePub and Kindle
Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.