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A Practical Guide to Global Point-of-Care Testing

A Practical Guide to Global Point-of-Care Testing
Author: Mark Shephard OAM
Publisher: CSIRO PUBLISHING
Total Pages: 650
Release: 2016-11-01
Genre: Medical
ISBN: 1486305202

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Point-of-care testing (POCT) refers to pathology testing performed in a clinical setting at the time of patient consultation, generating a rapid test result that enables informed and timely clinical action to be taken on patient care. It offers patients greater convenience and access to health services and helps to improve clinical outcomes. POCT also provides innovative solutions for the detection and management of chronic, acute and infectious diseases, in settings including family practices, Indigenous medical services, community health facilities, rural and remote areas and in developing countries, where health-care services are often geographically isolated from the nearest pathology laboratory. A Practical Guide to Global Point-of-Care Testing shows health professionals how to set up and manage POCT services under a quality-assured, sustainable, clinically and culturally effective framework, as well as understand the wide global scope and clinical applications of POCT. The book is divided into three major themes: the management of POCT services, a global perspective on the clinical use of POCT, and POCT for specific clinical settings. Chapters within each theme are written by experts and explore wide-ranging topics such as selecting and evaluating devices, POCT for diabetes, coagulation disorders, HIV, malaria and Ebola, and the use of POCT for disaster management and in extreme environments. Figures are included throughout to illustrate the concepts, principles and practice of POCT. Written for a broad range of practicing health professionals from the fields of medical science, health science, nursing, medicine, paramedic science, Indigenous health, public health, pharmacy, aged care and sports medicine, A Practical Guide to Global Point-of-Care Testing will also benefit university students studying these health-related disciplines.


Point of Care Diagnostics

Point of Care Diagnostics
Author: Great Britain. Department of Trade and Industry
Publisher:
Total Pages: 60
Release: 2004
Genre:
ISBN:

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Mobile Point-of-Care Monitors and Diagnostic Device Design

Mobile Point-of-Care Monitors and Diagnostic Device Design
Author: Walter Karlen
Publisher: CRC Press
Total Pages: 190
Release: 2018-09-03
Genre: Medical
ISBN: 1351831615

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Efficient mobile systems that allow for vital sign monitoring and disease diagnosis at the point of care can help combat issues such as rising healthcare costs, treatment delays in remote and resource-poor areas, and the global shortage of skilled medical personnel. Covering everything from sensors, systems, and software to integration, usability, and regulatory challenges, Mobile Point-of-Care Monitors and Diagnostic Device Design offers valuable insight into state-of-the-art technologies, research, and methods for designing personal diagnostic and ambulatory healthcare devices. Presenting the combined expertise of contributors from various fields, this multidisciplinary text: Gives an overview of the latest mobile health and point-of-care technologies Discusses portable diagnostics devices and sensors, including mobile-phone-based health systems Explores lab-on-chip systems as well as energy-efficient solutions for mobile point-of-care monitors Addresses computer vision and signal processing for real-time diagnostics Considers interface design for lay healthcare providers and home users Mobile Point-of-Care Monitors and Diagnostic Device Design provides important background information about the design process of mobile health and point-of-care devices, using practical examples to illustrate key aspects related to instrumentation, information processing, and implementation.


Revolutionizing Tropical Medicine

Revolutionizing Tropical Medicine
Author: Kerry Atkinson
Publisher: John Wiley & Sons
Total Pages: 768
Release: 2019-05-23
Genre: Science
ISBN: 1119282659

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A comprehensive resource describing innovative technologies and digital health tools that can revolutionize the delivery of health care in low- to middle-income countries, particularly in remote rural impoverished communities Revolutionizing Tropical Medicine offers an up-to-date guide for healthcare and other professionals working in low-resource countries where access to health care facilities for diagnosis and treatment is challenging. Rather than suggesting the expensive solution of building new bricks and mortar clinics and hospitals and increasing the number of doctors and nurses in these deprived areas, the authors propose a complete change of mindset. They outline a number of ideas for improving healthcare including rapid diagnostic testing for infectious and non-infectious diseases at a point-of-care facility, together with low cost portable imaging devices. In addition, the authors recommend a change in the way in which health care is delivered. This approach requires task-shifting within the healthcare provision system so that nurses, laboratory technicians, pharmacists and others are trained in the newly available technologies, thus enabling faster and more appropriate triage for people requiring medical treatment. This text: Describes the current burden of communicable and non-communicable diseases in low- to middle-income countries throughout the world Describes the major advances in healthcare outcomes in low-to middle-income countries derived from implementation of the United Nations/World Health Organisation’s 2000 Millennium Development Goals Provides a review of inexpensive rapid diagnostic point-of-care tests for infectious diseases in low-resource countries, particularly for people living in remote rural areas Provides a review of other rapid point-of-care services for assessing hematological function, biochemical function, renal function, hepatic function and status including hepatitis, acid-base balance, sickle cell disease, severe acute malnutrition and spirometry Explores the use of low-cost portable imaging devices for use in remote rural areas including a novel method of examining the optic fundus using a smartphone and the extensive value of portable ultrasound scanning when x-ray facilities are not available Describes the use of telemedicine in the clinical management of both children and adults in remote rural settings Looks to the future of clinical management in remote impoverished rural settings using nucleic acid identification of pathogens, the use of nanoparticles for water purification, the use of drones, the use of pulse oximetry and the use of near-infrared spectroscopy Finally, it assesses the potential for future healthcare improvement in impoverished areas and how the United Nations/World Health Organization 2015 Sustainable Development Goals are approaching this. Written for physicians, infectious disease specialists, pathologists, radiologists, nurses, pharmacists and other health care workers, as well as government healthcare managers, Revolutionizing Tropical Medicine is a new up-to-date essential and realistic guide to treating and diagnosing patients in low-resource tropical countries based on new technologies.


Implementation and Scale Up of Point of Care (POC) Diagnostics in Resource-Limited Settings

Implementation and Scale Up of Point of Care (POC) Diagnostics in Resource-Limited Settings
Author: Tivani Mashamba-Thompson
Publisher:
Total Pages: 154
Release: 2020-10-13
Genre:
ISBN: 9783039431700

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Scale up and implementation of new point-of-care (POC) diagnostics is a global health priority to enable the adoption of new evidence-based POC diagnostics and to replicate and extend the reach of POC diagnostics. Global private and public sector agencies have significantly increased their investment in the development of POC diagnostics to meet the unmet needs of patients in resource-limited settings, particularly disease burdened settings with limited access to laboratory infrastructure. However, previous research has demonstrated that the availability of health technologies in these settings does not always guarantee patient-centered outcomes. The applicability, effectiveness and sustainability of diagnostic technologies is affected by the involvement of all stakeholders during planning and implementation, which must be relevant to each specific context and sensitive to local culture. Factors such as infrastructure, resources, values and characteristics of participants can influence the implementation, scalability and sustainability of health interventions such as POC diagnostics. This book, "Implementation and Scale up of Point of Care (POC) Diagnostics in Resource-Limited Settings", presents literature reviews and primary research studies focusing on the implementation and scale up of POC diagnostics in resource-limited settings.


Development of Point-of-care Diagnostic Technologies for Global and Mental Health

Development of Point-of-care Diagnostic Technologies for Global and Mental Health
Author: Elizabeth Grace Rey
Publisher:
Total Pages: 120
Release: 2019
Genre:
ISBN:

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Access to diagnostic testing and screening technologies helps to improve patient care by enabling early treatment and monitoring of patient condition. Most of these technologies, however, rely on laboratory infrastructure and are expensive and time-consuming. In many limited-resource settings, these challenges are too great to overcome, preventing patient access to early diagnosis and screening. Point-of-care diagnostic technologies are designed to fill this need, providing low-cost, easy-to-use, and rapid testing. Lateral flow assays (LFAs) represent a simple platform for biomarker-based point-of-care diagnostics with very low cost and a rapid result. Antigen-antibody binding forms the basis of these tests, with labeled antibodies or proteins typically providing an optical signal that can either be seen by eye or analyzed using imaging devices. Microfluidic assays are another form of biomarker analysis that can be designed to incorporate more complex assays with more steps than a traditional LFA. In this work, we describe our efforts to develop novel and improved immunoassays for use at the point of care based on LFA and microfluidic technologies. The first three chapters of this dissertation describe our work on three different applications of lateral flow technology. We will first discuss our improvements to the detection range of an LFA through periodic measurement of the developing signal and kinetic analysis of the result. This work demonstrated our ability to overcome the high-dose hook effect without altering the LFA or the steps required by the user. Next, we present our point-of-care system for determination of folate status in serum. This technology provides a method for measuring folate concentration in serum without the use of complex technology. Our third lateral flow technology is an LFA to measure cortisol concentration in saliva. This LFA was validated in saliva samples from a human study that analyzed participant alertness and cortisol levels. Our final work describes the design of a microfluidic system for improved sensitivity in measurement of cortisol concentration in saliva. This system incorporates sample collection, filtration, treatment, and transfer to the microfluidic assay. An all-in-one device interacts with a disposable cassette to pump saliva into the microfluidic chip and provide a result.


Global Point of Care

Global Point of Care
Author: Gerald J. Kost
Publisher:
Total Pages:
Release: 2014-07
Genre:
ISBN: 9781594251726

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Point of Care Diagnostics

Point of Care Diagnostics
Author:
Publisher:
Total Pages: 60
Release: 2004
Genre: Diagnosis
ISBN:

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Improving Diagnosis in Health Care

Improving Diagnosis in Health Care
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 473
Release: 2015-12-29
Genre: Medical
ISBN: 0309377722

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Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care, a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001), finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€"has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety.


In-Vitro Diagnostic Devices

In-Vitro Diagnostic Devices
Author: Chao-Min Cheng
Publisher: Springer
Total Pages: 111
Release: 2015-07-16
Genre: Technology & Engineering
ISBN: 3319197371

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Addressing the origin, current status, and future development of point-of-care diagnostics, and serving to integrate knowledge and tools from Analytical Chemistry, Bioengineering, Biomaterials, and Nanotechnology, this book focusses on addressing the collective and combined needs of industry and academia (including medical schools) to effectively conduct interdisciplinary research. In addition to summarizing and detailing developed diagnostic devices, this book will attempt to point out the possible future trends of development for point-of-care diagnostics using both scientifically based research and practical engineering needs with the aim to help novices comprehensively understand the development of point-of-care diagnostics. This includes demonstrating several common but critical principles and mechanisms used in point-of-care diagnostics that address practical needs (e.g., disease or healthcare monitoring) using two well-developed examples so far: 1) blood glucose meters (via electrochemistry); and, 2) pregnancy tests (via lateral flow assay). Readers of this book will come to fully comprehend how to develop point-of-care diagnostics devices, and will be inspired to contribute to a critical global cause – the development of inexpensive, effective, and portable in vitro diagnostics tools (for any purpose) that can be used either at home or in resource limited areas.