Genetics Of Hypertension PDF Download
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| Author | : Anna F. Dominiczak |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 284 |
| Release | : 2007-01-01 |
| Genre | : Medical |
| ISBN | : 0444514562 |
Download Genetics of Hypertension Book in PDF, ePub and Kindle
Classic and modern tools of genetics have been applied to hypertension research for some 20 years. This volume in the Handbook of Hypertension series aims to go beyond a simple summary of discoveries and provides a critical commentary on many controversial issues. It will be particularly useful for clinician scientists at all stages of their careers, graduate students and post-doctoral scientists as well as all those interested in cardiovascular medicine and research throughout the entire spectrum from bench to bedside. As in every relatively young area of research, the initial excitement over the early positive observations has not always been confirmed by subsequent larger studies with greater statistical power. Issues related to current recommendations on design of studies and their analysis are therefore included. Pharmacogenetics and pharmacogenomics have been the subjects of many debates in recent years and are of particular importance in hypertension as life-long treatments, frequently with multiple drugs are given to millions of people world-wide. A critical appraisal of this controversial topic is provided. Several chapters on experimental genetics of hypertension with a special focus on physiological genomics are also included.
| Author | : Maria Dorobantu |
| Publisher | : Springer |
| Total Pages | : 408 |
| Release | : 2019-03-30 |
| Genre | : Medical |
| ISBN | : 3319933205 |
Download Hypertension and Heart Failure Book in PDF, ePub and Kindle
This book explains how hypertension affects 20-50% of the adult population in developed countries. Heart failure is the result of the hypertension's effects on the heart and it represents a growing public health problem. In this context the international scientific community is continuously struggling to develop better strategies in screening, diagnosing and treating hypertension and its deleterious effects. Thus, this field is continuously changing, with new important information being added constantly. This volume will offer both insights into the intimate mechanisms of transition from hypertension to heart failure and clinical practice advice on the prevention and treatment of heart failure in hypertensive population. The mechanisms which explain the progression from hypertension to heart failure will be also covered exhaustively by offering two chapters referring to the diagnosis of heart failure in hypertensive population and one regarding echocardiography which is the most frequently used imaging method in clinical practice. The reader will be also provided with information on cardiovascular magnetic resonance which has the unique advantage of differentiating hypertensive heart failure from other pathologies associated with increased myocardial thickness. This book is a useful tool for clinicians but also to the research community interested in heart failure and consequences of hypertension on heart who want to be up-to-date with the new developments in the field.
| Author | : Anna F. Dominiczak |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 284 |
| Release | : 2007-01-01 |
| Genre | : Medical |
| ISBN | : 0444514562 |
Download Genetics of Hypertension Book in PDF, ePub and Kindle
Classic and modern tools of genetics have been applied to hypertension research for some 20 years. This volume in the Handbook of Hypertension series aims to go beyond a simple summary of discoveries and provides a critical commentary on many controversial issues. It will be particularly useful for clinician scientists at all stages of their careers, graduate students and post-doctoral scientists as well as all those interested in cardiovascular medicine and research throughout the entire spectrum from bench to bedside. As in every relatively young area of research, the initial excitement over the early positive observations has not always been confirmed by subsequent larger studies with greater statistical power. Issues related to current recommendations on design of studies and their analysis are therefore included. Pharmacogenetics and pharmacogenomics have been the subjects of many debates in recent years and are of particular importance in hypertension as life-long treatments, frequently with multiple drugs are given to millions of people world-wide. A critical appraisal of this controversial topic is provided. Several chapters on experimental genetics of hypertension with a special focus on physiological genomics are also included.
| Author | : Xi Cheng |
| Publisher | : Biota Publishing |
| Total Pages | : 67 |
| Release | : 2015-08-01 |
| Genre | : Medical |
| ISBN | : 161504695X |
Download Genetics of Hypertension Book in PDF, ePub and Kindle
Hypertension, or elevated blood pressure, is a major risk factor for various cardiovascular, renal diseases, and stroke. The form of hypertension with no identifiable cause is referred to as Essential Hypertension. Familial studies indicate that Essential Hypertension is heritable and, thereby, classical genetic approaches have been applied on both human and other mammalian models of hypertension to map the locations of the allelic variants within quantitative trait loci for blood pressure. The post genome era has further elevated this area of research into large-scale genome-wide association studies of hypertension in humans. Collectively, these studies have resulted in the prioritization and cataloging of several genomic regions containing allelic variants as candidates linked or associated with essential hypertension. Further, they are providing evidence to suggest that the inheritance of hypertension is rather complex, encompassing multiple variants both within protein-coding and non-coding annotations, each of which may act independently or interactively with other genes and/or environmental factors to differentially regulate blood pressure. This book provides an overview of the various methods employed to study the genetics of hypertension and discuss the progress and prospects of this area of research that may contribute towards individualized clinical management of hypertension in the future.
| Author | : Jonathan Elliott |
| Publisher | : Springer Nature |
| Total Pages | : 374 |
| Release | : 2020-01-29 |
| Genre | : Science |
| ISBN | : 3030330206 |
Download Hypertension in the Dog and Cat Book in PDF, ePub and Kindle
This book provides an in-depth review on various aspects of canine and feline hypertension. Physiology, pathophysiology, epidemiology and pathological consequences of high blood pressure in cats and dogs are discussed. A comparative approach is taken, the underpinning research is critically evaluated and knowledge gaps identified. In addition, the reader is presented with evidence-based treatment strategies. The book targets researchers, graduate students and clinical specialists in small animal internal medicine as well as veterinary clinicians with interest in nephrology, cardiology, neurology and ophthalmology.
| Author | : Toshio Nakanishi |
| Publisher | : Springer Nature |
| Total Pages | : 374 |
| Release | : 2020-02-28 |
| Genre | : Medical |
| ISBN | : 9811511853 |
Download Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension Book in PDF, ePub and Kindle
This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.
| Author | : Madhu Khullar |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 250 |
| Release | : 2012-03-09 |
| Genre | : Medical |
| ISBN | : 9535102826 |
Download Genetics and Pathophysiology of Essential Hypertension Book in PDF, ePub and Kindle
This book, authored by renowned researchers in the field of Hypertension Research, details the state of the art knowledge in genetics, genomics and pathophysiology of Essential hypertension, specifically the genetic determinants of hypertension and role of gene variants in response to anti-hypertensive therapy. Two chapters describe mitochondrial mutations in Essential hypertension and in hypertension associated Left ventricular hypertrophy, one chapter reviews in detail the global gene expression in hypertension, and an up to date treatise on pathophysiology of resistant hypertension is detailed in another chapter. Other topics included in the book are end organ damage, baroreceptor sensitivity and role of music therapy in essential hypertension.
| Author | : Norman M. Kaplan |
| Publisher | : Lippincott Williams & Wilkins |
| Total Pages | : 480 |
| Release | : 2010 |
| Genre | : Medical |
| ISBN | : 1605475033 |
Download Kaplan's Clinical Hypertension Book in PDF, ePub and Kindle
Listed as the #1 reference book for hypertension by the American Society for Hypertension in 2006, this new edition presents up-to-date, practical, evidence-based recommendations for treatment and prevention of all forms of hypertension.
| Author | : Gill Rumsby |
| Publisher | : Garland Science |
| Total Pages | : 319 |
| Release | : 2020-07-26 |
| Genre | : Science |
| ISBN | : 1000144690 |
Download Molecular Endocrinology Book in PDF, ePub and Kindle
This volume in the Human Molecular Genetics series is an invaluable text for endocrinologists wishing to update their knowledge. It also provides an excellent grounding in the basic genetics of molecular endocrinology and relevant analytical techniques.
| Author | : George L. Bakris |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 544 |
| Release | : 2017-01-03 |
| Genre | : Medical |
| ISBN | : 0323508766 |
Download Hypertension: A Companion to Braunwald's Heart Disease E-Book Book in PDF, ePub and Kindle
The third edition of Hypertension: A Companion to Braunwald's Heart Disease, by Drs. George L. Bakris and Matthew Sorrentino, focuses on every aspect of managing and treating patients who suffer from hypertensive disorders. Designed for cardiologists, endocrinologists and nephrologists alike, this expansive, in-depth review boasts expert guidance from contributors worldwide, keeping you abreast of the latest developments from basic science to clinical trials and guidelines. Features expert guidance from worldwide contributors in cardiology, endocrinology, neurology and nephrology. Covers behavior management as an integral part of treatment plans for hypertensives and pre-hypertensives. Covers new developments in epidemiology, pathophysiology, immunology, clinical findings, laboratory testing, invasive and non-invasive testing, risk stratification, clinical decision-making, prognosis, and management. Includes chapters on hot topics such as hypertension as an immune disease; sleep disorders including sleep apnea, a major cause of hypertension; a novel chapter on environmental pollution and its contribution to endothelial dysfunction, and more! Equips you with the most recent guidelines from the major societies. Updates sourced from the main Braunwald's Heart Disease text. Highlights new combination drug therapies and the management of chronic complications of hypertension.
