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| Author | : Beth N. Peshkin |
| Publisher | : IOS Press |
| Total Pages | : 160 |
| Release | : 2007 |
| Genre | : Breast |
| ISBN | : 9781586037932 |
A testament to how far the field of genetic counseling for breast cancer susceptibility has advanced since the mid-1990s, following the cloning of two major breast (and ovarian) cancer susceptibility genes, BRCA1 and BRCA2.
| Author | : Katherine A. Schneider |
| Publisher | : John Wiley & Sons |
| Total Pages | : 498 |
| Release | : 2011-10-26 |
| Genre | : Medical |
| ISBN | : 1118119916 |
Important scientific discoveries and ever-changing guidelines for how to identify and manage patients with hereditary cancer syndromes are constantly evolving. This Third Edition of Counseling About Cancer is completely updated and expanded to feature five entirely new chapters on breast cancer, colon cancer, other solid tumors, clients and families, and genetic test results and follow-up. This is the only reference and clinical book on the market for cancer genetics counselors and other healthcare providers who must quickly assimilate complex and ever-changing data on the hereditary risk for cancer.
| Author | : Katherine A. Schneider |
| Publisher | : John Wiley & Sons |
| Total Pages | : 548 |
| Release | : 2023-05-15 |
| Genre | : Medical |
| ISBN | : 1119466466 |
Counseling About Cancer A key resource for all genetic counselors and other healthcare providers, this comprehensive reference has been completely updated and reorganized for its fourth edition Over 50 hereditary cancer predisposition genes have now been identified. Genetic testing can be a powerful tool in assessing individual cancer risk and creating robust medical plans, but can also be a complex process, with personal and familial factors carrying real emotional weight. As such, genetic counseling for patients and their families during the process of genetic testing is critical. Counseling about Cancer: Strategies for Genetic Counseling is the only comprehensive resource available for clinicians who want to understand and apply these dimensions of patient care. This updated and reorganized edition provides detailed information designed to be incorporated in a variety of clinical and health-care contexts. Updated with the latest guidance and research, it promises to continue as the indispensable guide to this challenging subject. Readers of the fourth edition of Counseling about Cancer will also find: New chapters analyzing pediatric cancer syndromes, genetic testing technology, and more Increased focus on gynecological cancer syndromes and related genes Detailed case studies to reinforce themes of each chapter Counseling about Cancer is a useful reference for genetic counselors and other healthcare providers looking to familiarize themselves with best practices of patient counseling and care.
| Author | : Claudine Isaacs |
| Publisher | : CRC Press |
| Total Pages | : 402 |
| Release | : 2007-09-19 |
| Genre | : Medical |
| ISBN | : 1420020366 |
Intended for medical oncologists, surgeons, obstetricians, gynecologists, geneticists, genetic counselors, and primary care physicians, this text presents the epidemiological, biological, and clinical issues associated with hereditary breast cancer. It offers clear guidance on the application and utilization of cancer risk assessment models, geneti
| Author | : Seigo Nakamura |
| Publisher | : Springer Nature |
| Total Pages | : 324 |
| Release | : 2021-10-20 |
| Genre | : Medical |
| ISBN | : 9811645213 |
This highly informative and clearly written book presents the basic science and the latest data on hereditary breast and ovarian cancer (HBOC) to provide an up-to-date and holistic overview of the disease. It starts off by presenting the molecular mechanisms, genetic testing and counseling, and variants of unknown significance (VUS) to help readers understand the contemporary interpretation of the disease. Further chapters focus on the surveillance, diagnosis and treatment, including chemoprevention, risk reduction and drug development based on molecular mechanisms. It also includes a chapter on the latest findings from the HBOC database, ethical issues and the parp inhibitors, and discusses innovative thinking to manage and understand the disease. Hereditary Breast and Ovarian Cancer - Molecular Mechanism and Clinical Practice offers breast surgeons, medical oncologists, gynecological oncologists and genetic counselors a comprehensive overview of the disease. Providing insights into recent scientific findings and further avenues for investigation, it is also a thought-provoking and informative read for researchers and scholars.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 34 |
| Release | : 2001-06-04 |
| Genre | : Medical |
| ISBN | : 0309075505 |
X-ray mammography screening is the current mainstay for early breast cancer detection. It has been proven to detect breast cancer at an earlier stage and to reduce the number of women dying from the disease. However, it has a number of limitations. These current limitations in early breast cancer detection technology are driving a surge of new technological developments, from modifications of x-ray mammography such as computer programs that can indicate suspicious areas, to newer methods of detection such as magnetic resonance imaging (MRI) or biochemical tests on breast fluids. To explore the merits and drawbacks of these new breast cancer detection techniques, the Institute of Medicine of the National Academy of Sciences convened a committee of experts. During its year of operation, the committee examined the peer-reviewed literature, consulted with other experts in the field, and held two public workshops. In addition to identifying promising new technologies for early detection, the committee explored potential barriers that might prevent the development of new detection methods and their common usage. Such barriers could include lack of funding from agencies that support research and lack of investment in the commercial sector; complicated, inconsistent, or unpredictable federal regulations; inadequate insurance reimbursement; and limited access to or unacceptability of breast cancer detection technology for women and their doctors. Based on the findings of their study, the committee prepared a report entitled Mammography and Beyond: Developing Technology for Early Detection of Breast Cancer, which was published in the spring of 2001. This is a non-technical summary of that report.
| Author | : Barbara T. Zimmerman |
| Publisher | : Univ. Press of Mississippi |
| Total Pages | : 128 |
| Release | : 2009-09-18 |
| Genre | : Health & Fitness |
| ISBN | : 1604730447 |
This book by a scientist whose background is in cellular and molecular biology examines the fearsome disease that strikes one in eight women in the United States. Although women are more likely to die of heart disease or of lung cancer, a diagnosis of breast cancer is the medical pronouncement that a woman is most likely to fear. It kills more than 40,000 Americans annually. Why are some women more vulnerable than others? The interplay between genetics and environment is suspected. Thus this book for general readers will help them understand the genetic basis of both sporadic and inherited breast cancers. Although only five to ten percent of breast cancer patients have inherited mutations in these genes, all women need to understand the genetic implications of the disease. In clear, concise language Barbara T. Zimmerman guides the reader through the complexities, discussing in detail the genes that are known to increase susceptibility and the ways they are passed on. Examining the general biology of breast cancer, Zimmerman describes how sporadic and inherited forms of the disease arise and how the location of the tumors can affect the body. She discusses genetic mutations and their roles in the development of tumors and tells how these potentially cancer-inducing genes were discovered. Covered too are the issues of risk, prevention, screening, diagnosis, therapy, and genetic testing and counseling. Zimmerman concludes with a comprehensive analysis of current research and with an emphasis on how a woman's understanding of inherited breast cancer can help doctors seeking to design better methods for prevention and therapy. A useful list of resources for further information about the genetic causes of breast cancer is included.
| Author | : |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 1999 |
| Genre | : |
| ISBN | : |
The present study aims to increase a woman's knowledge of: (1) the factors that determine genetic predisposition to breast/ovarian cancer, (2) personal family history and other risk factors, (3) the benefits and drawbacks of genetic testing for breast/ovarian cancer, (4) the range of surveillance and preventive behaviors available and, (5) the process of genetic testing. Participants will be 200 women who have contacted the Cancer Information Service (CIS) requesting information on inherited breast/ovarian cancer. Women will be randomly assigned to a standard or enhanced intervention testing the effectiveness of the CIS in increasing a woman's knowledge of inherited disease, risk assessment and genetic testing. As planned, this first year was dedicated to a formative evaluation of the informational/emotional needs of women pursuing risk assessment services. The structured interviews and focus groups conducted with women from the lay population, women at high risk and genetic counselors informed the development of the enhanced intervention. The interviews/groups supported previous research demonstrating that women are unprepared for and have limited knowledge about the process and outcomes of risk assessment for genetic predisposition to breast/ovarian cancer. A comprehensive training program and formalized standard protocol will ensure competence and consistency when accrual begins in the Pall.
| Author | : Sue Friedman |
| Publisher | : JHU Press |
| Total Pages | : 320 |
| Release | : 2012-03-01 |
| Genre | : Health & Fitness |
| ISBN | : 1421404451 |
"Be informed. Be empowered. Be well." If you are concerned that the cancer in your family is hereditary, you face difficult choices. Should you have a blood test that may reveal whether you have a high likelihood of disease? Do you preemptively treat a disease that may never develop? How do you make decisions now that will affect the rest of your life? This helpful, informative guide answers your questions as you confront hereditary breast and ovarian cancer. Developed by Facing Our Risk of Cancer Empowered (FORCE), the nation’s only nonprofit organization dedicated to supporting families affected by hereditary breast and ovarian cancer, this book stands alone among breast and ovarian cancer resources. Equal parts health guide and memoir, it defines complex issues facing previvors and survivors and provides solutions with a fresh, authoritative voice. Written by three passionate advocates for the hereditary cancer community who are themselves breast cancer survivors, Confronting Hereditary Breast and Ovarian Cancer dispels myths and misinformation and presents practical risk-reducing alternatives and decision-making tools. Including information about genetic counseling and testing, preventive surgery, and fertility and family planning, as well as explanations of health insurance coverage and laws protecting genetic privacy, this resource tackles head-on the challenges of living in a high-risk body. Confronting hereditary cancer is a complex, confusing, and highly individual journey. With its unique combination of the latest research, expert advice, and compelling personal stories, this book gives previvors, survivors, and their family members the guidance they need to face the unique challenges of hereditary cancer.
| Author | : Gail L. Shaw |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 209 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 1461546990 |
Cancer genetics is a quickly growing field within oncology. The ability to identify individuals at high risk for cancer improves the chance of early prevention and detection of cancer. The results of genetic testing affect quality of life, employment, and ability to be insured. This volume will provide an overview of cancer genetics, inherited cancer susceptibility, and available services and testing, including both the risks and benefits of testing. Some of the topics covered include: genetics of breast and ovarian cancer, testing minors for inherited cancer risk, chemoprevention of heritable cancer risk, genetics of colorectal cancer, insurance issues in genetic testing for cancer, ethical and legal issues in genetic testing for cancer susceptibility, testing for breast cancer risk in the Ashkenazim, estimating individualized risk of breast cancer, genetic counseling for the individual with inherited cancer susceptibility, and components of a genetic cancer risk clinic. While heritable cancers account for between five and ten percent of all cancer cases, molecular alterations attributable to specific inherited cancer susceptibility may give us important clues into the mechanism by which cancer occurs, not only in predisposed individuals, but also for sporadic cases.
