Genetic And Phenotypic Characterization Of Maternal Effect Sterile Genes In Caenorhabditis Elegans PDF Download
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Author | : Carol Marie Garvin |
Publisher | : |
Total Pages | : 222 |
Release | : 1996 |
Genre | : |
ISBN | : |
Download Genetic and Phenotypic Characterization of Maternal-effect Sterile Genes in Caenorhabditis Elegans Book in PDF, ePub and Kindle
Author | : Paula Ruth Martin |
Publisher | : |
Total Pages | : 182 |
Release | : 1991 |
Genre | : |
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Download Genetic and Phenotypic Analysis of Grandchildless Loci in Caenorhabditis Elegans Book in PDF, ePub and Kindle
Author | : Ryuji Minasaki |
Publisher | : |
Total Pages | : 59 |
Release | : 2007 |
Genre | : |
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Download Genetic and Molecular Characterization of Two Maternal Effect Genes Required for Caenorhabditis Elegans Development Book in PDF, ePub and Kindle
Author | : Patricia Leigh Graham |
Publisher | : |
Total Pages | : 394 |
Release | : 1992 |
Genre | : |
ISBN | : |
Download Genetic Characterization of Genes Regulating Germline Sex Determination in Caenorhabditis Elegans Book in PDF, ePub and Kindle
Author | : Joseph Veyhl |
Publisher | : |
Total Pages | : |
Release | : 2013 |
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Download The Characterization of a Novel Cell Migration Gene with a Maternal-effect and Temperature Sensitivity in Caenorhabditis Elegans Book in PDF, ePub and Kindle
Author | : Melinda Lee Moseley |
Publisher | : |
Total Pages | : 280 |
Release | : 1996 |
Genre | : |
ISBN | : |
Download Genetic and Molecular Characterization of Gut-2, a Gene Required for Early Blastomere Specification in Caenorhabditis Elegans Book in PDF, ePub and Kindle
Author | : Jason Burgess |
Publisher | : |
Total Pages | : 190 |
Release | : 2002 |
Genre | : Caenorhabditis elegans |
ISBN | : |
Download Phenotypic and Molecular Analysis of the Maternal Effect Associated with Mutations in the Clk-1 Gene of Caenorhabditis Elegans Book in PDF, ePub and Kindle
"Mutations in the Caenorhabditis elegans maternal-effect gene clk-1 result in a highly pleiotropic phenotype, characterized by a general slow down in embryonic and larval development, as well as a slowing down of adult behaviors including defecation, pharyngeal pumping and swimming. First generation homozygous clk-1 mutants descended from a heterozygous mother are fully rescued for these mutant phenotypes. It has been shown that CLK-1 protein is a hydroxylase that acts in the conversion of demethoxyubiquinone (DMQ) to 5-hydroxyubiquinone, in the ubiquinone (Q) biosynthesis pathway. Consequently, clk-1 mutants accumulate the Q9 precursor, DMQ9 (the subscript refers to the length of the isoprenoid side chain). Here, I show that the profound maternal rescue observed in clk-1 maternally rescued animals is due to presence of the CLK-1 protein throughout larval development, in sufficient amounts to catalyze the production of Q9. clk-1 mutants have been shown to have a dietary requirement for Q8 due to their inability to synthesize Q9. I demonstrate that clk-1 maternally rescued animals have sufficient amounts of Q 9 to complete larval development and produce an almost full brood when raised on a Q8 deficient E. coli strain. I also show that prolonged arrest at the first larval stage, which is likely to result in degradation of any maternally contributed mRNA or protein, brings about a Clk mutant phenotype in maternally rescued animals. Finally, I reveal that the Clk mutant phenotype can be rescued at any larval stage by ectopic expression of CLK-1, suggesting that there is no developmental window for the rescue of clk-1 mutants by CLK-1. These results identify perdurance of maternally contributed product throughout development as the mechanism that accounts for the maternal effect observed in clk-1 mutants." --
Author | : Niansheng N Cheng |
Publisher | : |
Total Pages | : 334 |
Release | : 1991 |
Genre | : |
ISBN | : |
Download Genetic and Developmental Analysis of Par-2, a Gene Required for Cytoplasmic Localization and Cleavage Patterning in Caenorhabditis Elegans Book in PDF, ePub and Kindle
Author | : Cathy Caron |
Publisher | : |
Total Pages | : 146 |
Release | : 1995 |
Genre | : |
ISBN | : |
Download Phenotypic and Molecular Analysis of Zyg-1 Book in PDF, ePub and Kindle
Author | : Cheryl Lynn Johnson |
Publisher | : |
Total Pages | : |
Release | : 2012 |
Genre | : |
ISBN | : 9780494971086 |
Download Regulation of Germ-line Expression of the Caenorhabditis Elegans Gene Fem-1 by Maternal Transcripts Book in PDF, ePub and Kindle