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Genes Unveiled

Genes Unveiled
Author: Elio Endless
Publisher: Elio Endless Publishers
Total Pages: 0
Release: 2023-10-12
Genre: Science
ISBN: 9787202973271

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Genes Unveiled: Exploring the Secrets of Hereditary Science Are you intrigued by the mysteries of heredity and the fascinating world of genetics? Dive into the captivating story of Gregor Mendel, a remarkable figure whose groundbreaking work in biology and botany revolutionized our understanding of how traits are inherited from one generation to the next. Discover the Life of Gregor Mendel A Multifaceted Genius: Gregor Johann Mendel, also known as Johann Mendel, was not just a scientist but also an Augustinian bishop and educator. His life was a unique blend of spirituality and scientific curiosity. Birthplace of Genius: Born in Heinzendorf (now known as Hynice in the Czech Republic) in 1822, Mendel's journey from a humble Austrian Empire village to a renowned scientist is nothing short of inspiring. A Name That Defined Him: In 1837, he chose the name "Gregor" as his preferred name, a symbol of his evolving identity and commitment to his scientific pursuits. The Journey of Discovery A Naturalist at Heart: Mendel's deep connection with the natural world ignited his quest to unravel the secrets of heredity. Science Meets Spirituality: His role as an Augustinian bishop allowed him to bridge the realms of religion and reason, enhancing the depth and uniqueness of his scientific work. Foundations of Genetics: Mendel's most significant contribution, Mendelism, laid the mathematical foundation for genetics. He introduced the concepts of dominant and recessive traits and formulated the laws of segregation and independent assortment through meticulous pea plant experiments. Pioneering Research: His groundbreaking research set the stage for modern genetics, offering profound insights into the complex mechanisms governing trait inheritance. Quantitative Analysis: Mendel's innovative approach integrated quantitative analysis and statistical rigor, transforming the field of biology and opening new avenues for future research. The Unrecognized Genius A Tragic Ending: Mendel passed away in 1884 in Brunn (now Brno, Czech Republic), without receiving full recognition for his pioneering findings. Legacy of Progress: It took subsequent generations of scientists to build upon Mendel's foundation and unlock the intricacies of genetics, driving the field into new frontiers. A Harmonious Coexistence Scientific Investigation and Spiritual Commitment: Mendel's life exemplifies the harmony between scientific exploration, spiritual dedication, and intellectual curiosity. Enduring Legacy: His meticulous investigations and mathematical discoveries illuminated the fundamental principles of heredity, laying the enduring foundation for the emerging field of genetics. Genes Unveiled offers a captivating journey through the life and work of Gregor Mendel, a visionary scientist whose legacy continues to shape our understanding of the intricate dynamics of life. Delve into this remarkable story and unlock the secrets of hereditary science.


Mapping and Sequencing the Human Genome

Mapping and Sequencing the Human Genome
Author: National Research Council
Publisher: National Academies Press
Total Pages: 128
Release: 1988-01-01
Genre: Science
ISBN: 0309038405

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There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.


Reflections of Our Past

Reflections of Our Past
Author: John H. Relethford
Publisher: Routledge
Total Pages: 308
Release: 2018-03-26
Genre: Social Science
ISBN: 0429891717

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The rise of the multi-billion dollar ancestry testing industry points to one immutable truth about us as human beings: we want to know where we come from and who our ancestors were. John H. Relethford and Deborah A. Bolnick explore this topic and many more in this second edition of Reflections of Our Past. Where did modern humans come from and how important are the biological differences among us? Are we descended from Neandertals? How should we understand the connections between genetic ancestry, race, and identity? Were Native Americans the first to inhabit the Americas? Can we see evidence of the Viking invasions of Ireland a millennium ago even in the Irish of today? Through engaging examination of issues such as these, and using non-technical language, Reflections of Our Past shows how anthropologists use genetic information to suggest answers to fundamental questions about human history. By looking at genetic variation in the world today and in the past, we can reconstruct the recent and remote events and processes that have created the variation we see, providing a fascinating reflection of our genetic past.


Mastering Biotechnology: Unveiling the Secrets of Genetic Engineering

Mastering Biotechnology: Unveiling the Secrets of Genetic Engineering
Author: Dominic Front
Publisher: Richards Education
Total Pages: 255
Release:
Genre: Science
ISBN:

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Unlock the boundless potential of biotechnology with "Mastering Biotechnology: Unveiling the Secrets of Genetic Engineering." This comprehensive guide navigates readers through the intricate realms of genetic manipulation, molecular biology, and bioprocessing, offering a treasure trove of knowledge essential for aspiring biotechnologists and seasoned professionals alike. From unraveling the mysteries of DNA to harnessing the power of synthetic biology, each chapter delves into key concepts and cutting-edge techniques, providing a roadmap to mastering the intricate tools of the trade. Explore the frontiers of agricultural innovation, delve into the realms of medical breakthroughs, and discover how biotechnology is reshaping our world, from the laboratory bench to the global marketplace. With a keen eye on ethical considerations and societal impacts, "Mastering Biotechnology" is more than a guidebook—it's a beacon of insight into the ethical, legal, and social dimensions of biotechnological advancement. Whether you're a student, researcher, or industry professional, embark on a journey of discovery and empowerment with this indispensable companion to the fascinating world of biotechnology.


Reflections Of Our Past

Reflections Of Our Past
Author: John H Relethford
Publisher: Routledge
Total Pages: 244
Release: 2018-03-09
Genre: Social Science
ISBN: 0429977360

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Where did modern humans come from and how important are the biological differences among us? Are we descended from Neanderthals? How many races of people are there? Were Native Americans the first settlers of the New World? How can we tell if Thomas Jefferson had a child with Sally Hemings? Through an engaging examination of issues such as these, and using non-technical language, Reflections of Our Past shows how anthropologists use genetic information to test theories and define possible answers to fundamental questions in human history. By looking at genetic variation in the world today, we can reconstruct the recent and remote events and processes that created the variation we see, providing a fascinating reflection of our genetic past. Reflections of Our Past is a W. W. Howells Book Prize Winner and Choice Outstanding Academic Title.


Plant Long Non-Coding RNAs

Plant Long Non-Coding RNAs
Author: Julia A. Chekanova
Publisher: Humana Press
Total Pages: 480
Release: 2019-04-20
Genre: Science
ISBN: 9781493990443

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This volume focuses on various approaches to studying long non-coding RNAs (lncRNAs), including techniques for finding lncRNAs, localization, and observing their functions. The chapters in this book cover how to catalog lncRNAs in various plant species; determining subcellular localization; protein interactions; structures; and RNA modifications. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and innovative, Plant Long Non-Coding RNAs: Methods and Protocols is a valuable resource that aids researchers in understanding the functions of lncRNAs in different plant species, and helps them explore currently uncharted facets of plant biology.


New Horizons in Health

New Horizons in Health
Author: National Research Council
Publisher: National Academies Press
Total Pages: 225
Release: 2001-03-09
Genre: Social Science
ISBN: 0309072964

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New Horizons in Health discusses how the National Institutes of Health (NIH) can integrate research in the social, behavioral, and biomedical sciences to better understand the causes of disease as well as interventions that promote health. It outlines a set of research priorities for consideration by the Office of Behavioral and Social Sciences Research (OBSSR), with particular attention to research that can support and complement the work of the National Institutes of Health. By addressing the range of interactions among social settings, behavioral patterns, and important health concerns, it highlights areas of scientific opportunity where significant investment is most likely to improve nationalâ€"and globalâ€"health outcomes. These opportunities will apply the knowledge and methods of the behavioral and social sciences to contemporary health needs, and give attention to the chief health concerns of the general public.


The Society of Genes

The Society of Genes
Author: Itai Yanai
Publisher: Harvard University Press
Total Pages: 295
Release: 2016-01-11
Genre: Science
ISBN: 0674425022

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Nearly four decades ago Richard Dawkins published The Selfish Gene, famously reducing humans to “survival machines” whose sole purpose was to preserve “the selfish molecules known as genes.” How these selfish genes work together to construct the organism, however, remained a mystery. Standing atop a wealth of new research, The Society of Genes now provides a vision of how genes cooperate and compete in the struggle for life. Pioneers in the nascent field of systems biology, Itai Yanai and Martin Lercher present a compelling new framework to understand how the human genome evolved and why understanding the interactions among our genes shifts the basic paradigm of modern biology. Contrary to what Dawkins’s popular metaphor seems to imply, the genome is not made of individual genes that focus solely on their own survival. Instead, our genomes comprise a society of genes which, like human societies, is composed of members that form alliances and rivalries. In language accessible to lay readers, The Society of Genes uncovers genetic strategies of cooperation and competition at biological scales ranging from individual cells to entire species. It captures the way the genome works in cancer cells and Neanderthals, in sexual reproduction and the origin of life, always underscoring one critical point: that only by putting the interactions among genes at center stage can we appreciate the logic of life.


The Gene

The Gene
Author: Siddhartha Mukherjee
Publisher: Simon and Schuster
Total Pages: 624
Release: 2016-05-17
Genre: Medical
ISBN: 1476733538

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The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).


Unveiling the Tumor Microenvironment by Machine Learning to Develop New Immunotherapeutic Strategies (Volume I.B)

Unveiling the Tumor Microenvironment by Machine Learning to Develop New Immunotherapeutic Strategies (Volume I.B)
Author: Nan Zhang
Publisher: Frontiers Media SA
Total Pages: 297
Release: 2023-10-24
Genre: Medical
ISBN: 2832536301

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The tumor microenvironment (TME) plays a critical role in tumor proliferation, progression, and therapeutic responses. TME is a complex network of cancer cells, stromal cells, and, most importantly, infiltrating immune cells. Cancer cells regulate numerous biological functions through direct or indirect interaction with TME components. Emerging evidence suggests that TME crucially influences the response to both chemotherapy and immunotherapy. As scientific research has entered the big data era with the fast development of high-throughput sequencing technologies, machine learning has been gradually widely applied to extract important knowledge from big data bioinformatics. Thus, characterizing the TME landscape in cancer and identifying different immune-related TME phenotypes using machine learning-based bioinformatics analyses, in vitro experiments, and in vivo experiments are of great interest and significance.