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Genes, Enzymes, and Populations

Genes, Enzymes, and Populations
Author: Adrian Srb
Publisher: Springer Science & Business Media
Total Pages: 357
Release: 2012-12-06
Genre: Medical
ISBN: 1468428802

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The present volume includes the large majority of papers given at the symposium entitled "Fundamental Approaches to Plant and Animal Improvement," held at Cali, Colombia, in November, 1972. The primary focal points were on various genetic mechanisms, including gene action and mutation, the development of phenotypic attributes, and on evolution, including that controlled by man for agricultural purposes. In fact, very little referring in any particular way to animal improvement was included, while a great deal of attention was paid to higher plants and to microorganisms. On the other hand, both the population genetics of insects and insect control were considered. Thus Genes, Enzymes, and Populations, the title given to this published work, seems to me to represent somewhat more fairly the contents than does the original symposium title. Given the intent of the symposium, which is expressed in the original title, the published record cannot be expected to be a neatly packaged presentation of some highly defined subject matter. Indeed the diverse subjects represent some, but by no means all, of the varied and dynamic scientific activities that need to be components in the improvement and production of agriculturally Significant plants at a time when world populations are rapidly increasing and shortages of food occurring. In any case, the organizers of the symposium wisely decided that considerations of environment as well as of genetics should be introduced into the thinking of the group and that physiology and molecular biology could not be ignored.


Proteins, Enzymes, Genes

Proteins, Enzymes, Genes
Author:
Publisher: Yale University Press
Total Pages: 814
Release:
Genre: Biochemistry
ISBN: 9780300153590

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In this book a distinguished scientist-historian offers a critical account of how biochemistry and molecular biology emerged as major scientific disciplines from the interplay of chemical and biological ideas and practice. Joseph S. Fruton traces the historical development of these disciplines from antiquity to the present time, examines their institutional settings, and discusses their impact on medical, pharmaceutical, and agricultural practice.


Genetics of Populations

Genetics of Populations
Author: Philip W. Hedrick
Publisher: Gareth Stevens Publishing
Total Pages: 654
Release: 1983
Genre: Science
ISBN:

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Selection in Natural Populations

Selection in Natural Populations
Author: Jeffry B. Mitton
Publisher:
Total Pages: 240
Release: 1997
Genre: Enzymes
ISBN:

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In this book, Jeff Mitton explains the questions that geneticists hoped to answer by studying protein variation. He reviews the extensive literature on protein variation, describes the successes and failures of the research program, and evaluates the results of a rich and controversial body of research. The laboratory and field studies using protein polymorphisms revealed dynamic interactions among genotypes, fitness differentials, and fluctuating environmental conditions, and inadvertently wedded the fields of physiological ecology and population biology. Mitton's book is a useful analysis for all scientists interested in the genetic structure and evolution of populations.


The Evaluation of Forensic DNA Evidence

The Evaluation of Forensic DNA Evidence
Author: National Research Council
Publisher: National Academies Press
Total Pages: 271
Release: 1997-01-12
Genre: Science
ISBN: 0309121949

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In 1992 the National Research Council issued DNA Technology in Forensic Science, a book that documented the state of the art in this emerging field. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. J. Simpson. The Evaluation of Forensic DNA Evidence reports on developments in population genetics and statistics since the original volume was published. The committee comments on statements in the original book that proved controversial or that have been misapplied in the courts. This volume offers recommendations for handling DNA samples, performing calculations, and other aspects of using DNA as a forensic toolâ€"modifying some recommendations presented in the 1992 volume. The update addresses two major areas: Determination of DNA profiles. The committee considers how laboratory errors (particularly false matches) can arise, how errors might be reduced, and how to take into account the fact that the error rate can never be reduced to zero. Interpretation of a finding that the DNA profile of a suspect or victim matches the evidence DNA. The committee addresses controversies in population genetics, exploring the problems that arise from the mixture of groups and subgroups in the American population and how this substructure can be accounted for in calculating frequencies. This volume examines statistical issues in interpreting frequencies as probabilities, including adjustments when a suspect is found through a database search. The committee includes a detailed discussion of what its recommendations would mean in the courtroom, with numerous case citations. By resolving several remaining issues in the evaluation of this increasingly important area of forensic evidence, this technical update will be important to forensic scientists and population geneticistsâ€"and helpful to attorneys, judges, and others who need to understand DNA and the law. Anyone working in laboratories and in the courts or anyone studying this issue should own this book.


Population Genetics and Evolution

Population Genetics and Evolution
Author: Lawrence E. Mettler
Publisher: Prentice Hall
Total Pages: 232
Release: 1969
Genre: Science
ISBN:

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Genetics of Human Populations

Genetics of Human Populations
Author: Albert Jacquard
Publisher: Gareth Stevens Publishing
Total Pages: 202
Release: 1978
Genre: Medical
ISBN:

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Genetic Twists of Fate

Genetic Twists of Fate
Author: Stanley Fields
Publisher: MIT Press
Total Pages: 236
Release: 2013-02-08
Genre: Science
ISBN: 0262518643

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How tiny variations in our personal DNA can determine how we look, how we behave, how we get sick, and how we get well. News stories report almost daily on the remarkable progress scientists are making in unraveling the genetic basis of disease and behavior. Meanwhile, new technologies are rapidly reducing the cost of reading someone's personal DNA (all six billion letters of it). Within the next ten years, hospitals may present parents with their newborn's complete DNA code along with her footprints and APGAR score. In Genetic Twists of Fate, distinguished geneticists Stanley Fields and Mark Johnston help us make sense of the genetic revolution that is upon us. Fields and Johnston tell real life stories that hinge on the inheritance of one tiny change rather than another in an individual's DNA: a mother wrongly accused of poisoning her young son when the true killer was a genetic disorder; the screen siren who could no longer remember her lines because of Alzheimer's disease; and the president who was treated with rat poison to prevent another heart attack. In an engaging and accessible style, Fields and Johnston explain what our personal DNA code is, how a few differences in its long list of DNA letters makes each of us unique, and how that code influences our appearance, our behavior, and our risk for such common diseases as diabetes or cancer.


Gene Drives on the Horizon

Gene Drives on the Horizon
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 231
Release: 2016-08-28
Genre: Science
ISBN: 0309437873

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Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impact low and middle income countries. However, due to their intrinsic qualities of rapid spread and irreversibility, gene drive systems raise many questions with respect to their safety relative to public and environmental health. Because gene drive systems are designed to alter the environments we share in ways that will be hard to anticipate and impossible to completely roll back, questions about the ethics surrounding use of this research are complex and will require very careful exploration. Gene Drives on the Horizon outlines the state of knowledge relative to the science, ethics, public engagement, and risk assessment as they pertain to research directions of gene drive systems and governance of the research process. This report offers principles for responsible practices of gene drive research and related applications for use by investigators, their institutions, the research funders, and regulators.


Modern Biocatalysis

Modern Biocatalysis
Author: Gavin Williams
Publisher: Royal Society of Chemistry
Total Pages: 594
Release: 2018-05-31
Genre: Science
ISBN: 1788014537

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The synergy between synthetic biology and biocatalysis is emerging as an important trend for future sustainable processes. This book reviews all modern and novel techniques successfully implemented in biocatalysis, in an effort to provide better performing enzymatic systems and novel biosynthetic routes to (non-)natural products. This includes the use of molecular techniques in protein design and engineering, construction of artificial metabolic pathways, and application of computational methods for enzyme discovery and design. Stress is placed on current ‘hot’ topics in biocatalysis, where recent advances in research are defining new grounds in enzyme-catalyzed processes. With contributions from leading academics around the world, this book makes a ground-breaking contribution to this progressive field and is essential reading for graduates and researchers investigating (bio)catalysis, enzyme engineering, chemical biology, and synthetic biology.