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Molecular Biology of The Cell

Molecular Biology of The Cell
Author: Bruce Alberts
Publisher:
Total Pages: 0
Release: 2002
Genre: Cytology
ISBN: 9780815332183

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Gene Activity in Early Development

Gene Activity in Early Development
Author: Bozzano G Luisa
Publisher: Elsevier
Total Pages: 695
Release: 2012-12-02
Genre: Science
ISBN: 0323138438

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The new third edition of Gene Activity in Early Development reflects the ten years of technological progress since the last edition. Providing a unique blend of classical and molecular knowledge, it discusses all major embryonic systems from both a comparative and mechanistic point of view. In deriving overall interpretations of developmental phenomena, it brings into play all the disparate forms of evidence, including genetic, molecular, and cytological.**This book is written for any serious student or scholar entering the field, whether his or her background is in genetics, molecular biology, or embryology.


The Regulatory Genome

The Regulatory Genome
Author: Eric H. Davidson
Publisher: Elsevier
Total Pages: 303
Release: 2010-07-19
Genre: Science
ISBN: 0080455573

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Gene regulatory networks are the most complex, extensive control systems found in nature. The interaction between biology and evolution has been the subject of great interest in recent years. The author, Eric Davidson, has been instrumental in elucidating this relationship. He is a world renowned scientist and a major contributor to the field of developmental biology. The Regulatory Genome beautifully explains the control of animal development in terms of structure/function relations of inherited regulatory DNA sequence, and the emergent properties of the gene regulatory networks composed of these sequences. New insights into the mechanisms of body plan evolution are derived from considerations of the consequences of change in developmental gene regulatory networks. Examples of crucial evidence underscore each major concept. The clear writing style explains regulatory causality without requiring a sophisticated background in descriptive developmental biology. This unique text supersedes anything currently available in the market. The only book in the market that is solely devoted to the genomic regulatory code for animal development Written at a conceptual level, including many novel synthetic concepts that ultimately simplify understanding Presents a comprehensive treatment of molecular control elements that determine the function of genes Provides a comparative treatment of development, based on principles rather than description of developmental processes Considers the evolutionary processes in terms of the structural properties of gene regulatory networks Includes 42 full-color descriptive figures and diagrams


Epigenetic Gene Expression and Regulation

Epigenetic Gene Expression and Regulation
Author: Suming Huang
Publisher: Academic Press
Total Pages: 484
Release: 2015-10-19
Genre: Science
ISBN: 0128004711

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Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples. Reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies Helps readers understand how epigenetic marks are targeted, and to what extent transgenerational epigenetic changes are instilled and possibly passed onto offspring Chapters are replete with clinical examples to empower the basic biology with translational significance Offers more than 100 illustrations to distill key concepts and decipher complex science


New Horizons in Health

New Horizons in Health
Author: National Research Council
Publisher: National Academies Press
Total Pages: 225
Release: 2001-03-09
Genre: Social Science
ISBN: 0309072964

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New Horizons in Health discusses how the National Institutes of Health (NIH) can integrate research in the social, behavioral, and biomedical sciences to better understand the causes of disease as well as interventions that promote health. It outlines a set of research priorities for consideration by the Office of Behavioral and Social Sciences Research (OBSSR), with particular attention to research that can support and complement the work of the National Institutes of Health. By addressing the range of interactions among social settings, behavioral patterns, and important health concerns, it highlights areas of scientific opportunity where significant investment is most likely to improve nationalâ€"and globalâ€"health outcomes. These opportunities will apply the knowledge and methods of the behavioral and social sciences to contemporary health needs, and give attention to the chief health concerns of the general public.


Gene Expression at the Beginning of Animal Development

Gene Expression at the Beginning of Animal Development
Author: M.L. DePamphilis
Publisher: Elsevier
Total Pages: 300
Release: 2002-09-30
Genre: Medical
ISBN: 9780444510488

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The beginning of life may be a miracle to some, and a mystery to others, but it is certainly one of the most exciting and perhaps controversial fields of scientific investigation in the 21st century. Among the metazoa, life begins when an egg is fertilized by a sperm. The sperm provides a genetic blueprint from the father and perhaps some critical proteins. The egg provides a genetic blueprint from the mother together with a large reservoir of mRNAs and proteins that are required for DNA replication, cell division and the onset of zygotic gene expression. All of the thousands of genes in these two mature gametes are transcriptionally silent and remain so until fertilization. This work focuses on three biological systems, providing the reader with a clear understanding of the current state of affairs, and the ability to identify common principles as well as critical differences that are responsible for beginning the process of animal development. The essays presented will be of practical value to all those who are interested in improving fertilization in vitro, in designing novel methods of contraception, in developing preimplantation genetic diagnosis for various diseases, in cloning animals by transplanting nuclei from adult cells to an enucleated egg, and in the application of embryonic stem cells to curing genetic diseases or replacing damaged tissues. But above all, this volume is offered to those who simply have an insatiable curiosity about life and its beginnings.


Developmental Genetics

Developmental Genetics
Author: Gurbachan S. Miglani
Publisher: I. K. International Pvt Ltd
Total Pages: 782
Release: 2013-12-30
Genre: Genetics
ISBN: 8188237590

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Development is behind what one looks like. It is directed by genes, the units of heredity, which are made up to deoxyribonucleic acid (DNA) in all animals (including man), plants, microorganisms and most of the viruses except in some viruses where ribonucleic acid (RNA) is the genetic material. Developmental Genetics integrates the two disciplines of development and genetics into one. Key Features: Each chapter begins with a brief introduction and historical background. The text explains both classical and recent material. Various phenomena of developmental genetics explained with examples of animals, plant, bacteria and viruses. Text explained with suitable examples, illustrations, tables and figures. List of references and review questions given at the end of each chapter Exhaustive glossary, author index and subject index given at the end of the book. This book is essential reading for postgraduate in developmental genetics, teachers teaching this subject and developmental biologists conducting research in this area. It is also suitable for candidates preparing for ARS/UGC NET examination.