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Functional Metagenomics: Tools and Applications

Functional Metagenomics: Tools and Applications
Author: Trevor C. Charles
Publisher: Springer
Total Pages: 256
Release: 2017-10-09
Genre: Science
ISBN: 3319615106

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In this book, the latest tools available for functional metagenomics research are described.This research enables scientists to directly access the genomes from diverse microbial genomes at one time and study these “metagenomes”. Using the modern tools of genome sequencing and cloning, researchers have now been able to harness this astounding metagenomic diversity to understand and exploit the diverse functions of microorganisms. Leading scientists from around the world demonstrate how these approaches have been applied in many different settings, including aquatic and terrestrial habitats, microbiomes, and many more environments. This is a highly informative and carefully presented book, providing microbiologists with a summary of the latest functional metagenomics literature on all specific habitats.


The New Science of Metagenomics

The New Science of Metagenomics
Author: National Research Council
Publisher: National Academies Press
Total Pages: 170
Release: 2007-06-24
Genre: Science
ISBN: 0309106761

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Although we can't usually see them, microbes are essential for every part of human life-indeed all life on Earth. The emerging field of metagenomics offers a new way of exploring the microbial world that will transform modern microbiology and lead to practical applications in medicine, agriculture, alternative energy, environmental remediation, and many others areas. Metagenomics allows researchers to look at the genomes of all of the microbes in an environment at once, providing a "meta" view of the whole microbial community and the complex interactions within it. It's a quantum leap beyond traditional research techniques that rely on studying-one at a time-the few microbes that can be grown in the laboratory. At the request of the National Science Foundation, five Institutes of the National Institutes of Health, and the Department of Energy, the National Research Council organized a committee to address the current state of metagenomics and identify obstacles current researchers are facing in order to determine how to best support the field and encourage its success. The New Science of Metagenomics recommends the establishment of a "Global Metagenomics Initiative" comprising a small number of large-scale metagenomics projects as well as many medium- and small-scale projects to advance the technology and develop the standard practices needed to advance the field. The report also addresses database needs, methodological challenges, and the importance of interdisciplinary collaboration in supporting this new field.


Functional Metagenomics

Functional Metagenomics
Author: Maulin P Shah
Publisher: Elsevier
Total Pages: 246
Release: 2023-11-24
Genre: Science
ISBN: 0323986439

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Functional Metagenomics: Microbial Diversity, Interaction, and Application in Bioremediation uses a 20-chapter, easy-to-understand format to centralize the practical application ideas for functional metagenomics. This important resource not only includes chapters on next-generation sequencing technologies to study important biogeochemical cycles, degradation pathways and detoxification, but also gives insight into several tools that have been developed to integrate metadata and sequence data, allowing downstream comparative analyses of different datasets using several ecological indices.Content further explains the newly developed techniques for sequencing DNA; generating shorter fragments than Sanger sequencing techniques to quickly read larger sequences in a shorter amount of time. The content finally explores the role of metagenomics in studying microbial diversity, interaction and application in bioremediation studies and gives the reader overall detailed information regarding metagenomics, its application as well as techniques. Provides comprehensive information to readers on state-of-the-art applications in metagenomics Summarizes our current knowledge of the use of metagenomics and gives a novel and powerful insight into the already existing bioremediation process Gives an overall picture of metagenomics, its application, processes, and future prospects in the field of bioremediation


Microbial Metagenomics, Metatranscriptomics, and Metaproteomics

Microbial Metagenomics, Metatranscriptomics, and Metaproteomics
Author:
Publisher: Academic Press
Total Pages: 0
Release: 2013-10-08
Genre: Science
ISBN: 9780124078635

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This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers microbial metagenomics, metatranscriptomics, and metaproteomics, and includes chapters on such topics as in-solution FISH for single cell genome preparation, preparation of BAC libraries from marine microbial community DNA, and preparation of microbial community cDNA for metatranscriptomic analysis in marine plankton.


Metagenomics

Metagenomics
Author: Muniyandi Nagarajan
Publisher: Academic Press
Total Pages: 400
Release: 2017-10-29
Genre: Medical
ISBN: 0128134038

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Metagenomics: Perspectives, Methods, and Applications provides thorough coverage of the growing field of metagenomics. A diverse range of chapters from international experts offer an introduction to the field and examine methods for metagenomic analysis of microbiota, metagenomic computational tools, and recent metagenomic studies in various environments. The emphasis on application makes this text particularly useful for applied researchers, practitioners, clinicians and students seeking to employ metagenomic approaches to advance knowledge in the biomedical and life sciences. Case-study based application chapters examine topics ranging from viral metagenome profiling, metagenomics in oral disease and health, metagenomic insights into the human gut microbiome and metabolic syndromes, and more. Additionally, perspectives on future potential at the end of each chapter provoke new thought and motivations for continued study in this exciting and fruitful research area. Provides thorough coverage of the rapidly growing field of metagenomics, with an emphasis on applications of relevance to translational researchers, practitioners, clinicians and students Features a diverse range of chapters from international experts that offer an introduction to the field and examine methods for metagenomic analysis of microbiota, metagenomic computational tools and research pipelines Highlights perspectives on future potential at the end of each chapter to provoke new thought and motivations for continued study in this exciting and fruitful research area


Metagenomics for Microbiology

Metagenomics for Microbiology
Author: Jacques Izard
Publisher: Academic Press
Total Pages: 188
Release: 2014-11-07
Genre: Science
ISBN: 0124105084

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Concisely discussing the application of high throughput analysis to move forward our understanding of microbial principles, Metagenomics for Microbiology provides a solid base for the design and analysis of omics studies for the characterization of microbial consortia. The intended audience includes clinical and environmental microbiologists, molecular biologists, infectious disease experts, statisticians, biostatisticians, and public health scientists. This book focuses on the technological underpinnings of metagenomic approaches and their conceptual and practical applications. With the next-generation genomic sequencing revolution increasingly permitting researchers to decipher the coding information of the microbes living with us, we now have a unique capacity to compare multiple sites within individuals and at higher resolution and greater throughput than hitherto possible. The recent articulation of this paradigm points to unique possibilities for investigation of our dynamic relationship with these cellular communities, and excitingly the probing of their therapeutic potential in disease prevention or treatment of the future. Expertly describes the latest metagenomic methodologies and best-practices, from sample collection to data analysis for taxonomic, whole shotgun metagenomic, and metatranscriptomic studies Includes clear-headed pointers and quick starts to direct research efforts and increase study efficacy, eschewing ponderous prose Presented topics include sample collection and preparation, data generation and quality control, third generation sequencing, advances in computational analyses of shotgun metagenomic sequence data, taxonomic profiling of shotgun data, hypothesis testing, and mathematical and computational analysis of longitudinal data and time series. Past-examples and prospects are provided to contextualize the applications.


Introduction To Computational Metagenomics

Introduction To Computational Metagenomics
Author: Zhong Wang
Publisher: World Scientific
Total Pages: 210
Release: 2022-04-11
Genre: Science
ISBN: 9811242488

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Breakthroughs in high-throughput genome sequencing and high-performance computing technologies have empowered scientists to decode many genomes including our own. Now they have a bigger ambition: to fully understand the vast diversity of microbial communities within us and around us, and to exploit their potential for the improvement of our health and environment. In this new field called metagenomics, microbial genomes are sequenced directly from the habitats without lab cultivation. Computational metagenomics, however, faces both a data challenge that deals with tens of tera-bases of sequences and an algorithmic one that deals with the complexity of thousands of species and their interactions.This interdisciplinary book is essential reading for those who are interested in beginning their own journey in computational metagenomics. It is a prism to look through various intricate computational metagenomics problems and unravel their three distinctive aspects: metagenomics, data engineering, and algorithms. Graduate students and advanced undergraduates from genomics science or computer science fields will find that the concepts explained in this book can serve as stepping stones for more advanced topics, while metagenomics practitioners and researchers from similar disciplines may use it to broaden their knowledge or identify new research targets.


Antimicrobial Resistance in Wastewater Treatment Processes

Antimicrobial Resistance in Wastewater Treatment Processes
Author: Patricia L. Keen
Publisher: John Wiley & Sons
Total Pages: 501
Release: 2017-09-26
Genre: Science
ISBN: 1119192455

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Antimicrobial resistance is arguably the greatest threat to worldwide human health. This book evaluates the roles of human water use, treatment and conservation in the development and spread of antimicrobial resistance. Designed as a companion volume to Antimicrobial Resistance in the Environment (Wiley-Blackwell, 2012), this book is a multi-disciplinary synthesis of topics related to antimicrobial resistance and wastewater treatment processes. Antimicrobial Resistance in Wastewater Treatment Processes assembles detailed discussions written by many of the world's best-known experts in microbiology, civil engineering, chemistry, environmental science, public health and related fields. The book presents a collection of subjects that includes: Current knowledge of the role of the environment in development and spread of antimicrobial resistance Chemical analysis of antibiotics in environmental samples Molecular methods for analysis of antimicrobial resistance genes Advanced wastewater treatment processes and antimicrobial resistance effects Public perception of risk related to health consequences of antimicrobial resistance Public health implications of antimicrobial resistance with focus on wastewater treatment processes Antimicrobial resistance has gained a foothold in the global consciousness as a serious public health threat. There is a much greater appreciation for the role of the environment in the dissemination of antimicrobial resistance and the effects of pollutants that can potentially promote development of resistance in bacteria. Contaminants released from wastewater treatment plants are a concern. In Antimicrobial Resistance in Wastewater Treatment Processes, readers will be guided through examinations of the current science related to this important health issue.


Microbiome Drivers of Ecosystem Function

Microbiome Drivers of Ecosystem Function
Author: Javid A. Parray
Publisher: Elsevier
Total Pages: 490
Release: 2024-01-01
Genre: Science
ISBN: 044322398X

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Microbiome Drivers of Ecosystem Function focuses on the advancements in microbial technologies towards harnessing the microbiome for improved crop productivity and health that are at the frontier of agricultural sciences. It provides insights into the diversity of endophytic microbiomes and their potential utility in agricultural production.Increased crop yield through chemical interventions have limit thresholds and alternative, natural and/or integrated approaches are increasingly needed. Microbial inoculants among the ways in which food production efficiency can be improved. Plant growth-promoting soil organisms increase net crop uptake of soil nutrients, resulting in larger crops and higher yields of harvested food. These and other symbiotic associations between plants and microbes can ultimately be exploited for the increased food production necessary to feed the world, in addition to creating safer farming techniques that minimize ecological disruption.As a volume in the Microbiome Research in Plants and Soil series, Microbiome Drivers of Ecosystem Function serves as an ideal reference for researchers and students in the fields of agricultural biotechnology, biochemistry, environmental science, plant biology, agricultural sciences, and agricultural engineering. Provides insights on engineered microbes in sustainable agriculture, recent biotechnological developments, and future prospects Introduces microbes as chief ecological engineers in reinstating equilibrium in degraded ecosystems Presents the current state and development, as well as future challenges in studying plant-microbe interactions Discusses endophytic microbiomes and other microbial consortium with multifunctional plant growth-promoting attributes